Basic Information

Insect: Tinea trinotella
Gene Symbol: ZFHX3
Assembly: GCA_905220615.1
Location: HG992317.1:8415515-8422117[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.61 34 5.4 4.2 1 23 73 96 73 96 0.95

2 15 0.0043 0.24 12.2 0.1 1 23 103 126 103 126 0.95

3 15 0.0037 0.21 12.4 2.6 2 21 181 200 181 204 0.91

4 15 0.26 15 6.6 0.6 1 23 216 241 216 241 0.94

5 15 0.012 0.7 10.7 1.3 1 23 259 281 259 281 0.97

6 15 0.00078 0.044 14.5 0.4 2 23 288 310 287 310 0.96

7 15 0.00027 0.015 16.0 3.1 1 23 416 440 416 440 0.92

8 15 0.011 0.62 10.9 0.7 1 22 460 481 460 484 0.89

9 15 0.0011 0.062 14.0 0.2 1 23 531 555 531 555 0.93

10 15 3.4 1.9e+02 3.1 0.1 3 21 630 648 629 649 0.91

11 15 0.81 46 5.0 3.5 2 19 739 756 738 761 0.91

12 15 2.9e-05 0.0016 19.0 2.9 1 23 1270 1292 1270 1292 0.99

13 15 0.00075 0.042 14.6 0.3 1 23 1382 1404 1382 1404 0.98

14 15 0.0071 0.4 11.5 0.4 2 23 1542 1564 1541 1564 0.97

15 15 0.22 13 6.8 1.4 2 22 1790 1810 1789 1813 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.61	34	5.4	4.2	1	23	73	96	73	96	0.95
2	15	0.0043	0.24	12.2	0.1	1	23	103	126	103	126	0.95
3	15	0.0037	0.21	12.4	2.6	2	21	181	200	181	204	0.91
4	15	0.26	15	6.6	0.6	1	23	216	241	216	241	0.94
5	15	0.012	0.7	10.7	1.3	1	23	259	281	259	281	0.97
6	15	0.00078	0.044	14.5	0.4	2	23	288	310	287	310	0.96
7	15	0.00027	0.015	16.0	3.1	1	23	416	440	416	440	0.92
8	15	0.011	0.62	10.9	0.7	1	22	460	481	460	484	0.89
9	15	0.0011	0.062	14.0	0.2	1	23	531	555	531	555	0.93
10	15	3.4	1.9e+02	3.1	0.1	3	21	630	648	629	649	0.91
11	15	0.81	46	5.0	3.5	2	19	739	756	738	761	0.91
12	15	2.9e-05	0.0016	19.0	2.9	1	23	1270	1292	1270	1292	0.99
13	15	0.00075	0.042	14.6	0.3	1	23	1382	1404	1382	1404	0.98
14	15	0.0071	0.4	11.5	0.4	2	23	1542	1564	1541	1564	0.97
15	15	0.22	13	6.8	1.4	2	22	1790	1810	1789	1813	0.88

Sequence Information

Coding Sequence: ATGGTCATTTGTTTGTCCTCAGATCACAAAGAGCCCATTGATCAGAAGCCTGAATTAACACATGAGCAGAAAATGATGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATTTCACTAAAACTGAAAGAGAAGAGGAAAGAGAACGTGAACGAGAGCTTGATACCCCTGGCACCCATTCGTGCCCCTATTGCAATTTCAGCTGCAATAGCGAGATAAGATTACATGCCCATGTAGCAACGACTCATGGGGATTCTAGTCGTCATTTCATGTGTCCTCTTTGCCAAGATGCGTTTAAAGATCGCACAGCACTTGAACGACATGTAATGCAGATTCATTCTGTAAACTCTGAAGGTTTGCAACGATTACTATTATTAGTAGACCAAAGTCACTGGCTTAATGGTGGCAATCAAGCTCAAAGAGATGAAACACGACAGCAAGAAGACGAACGTGAAATATCTTCGCCAAGATCTGAGGGAAGCGCTGATGGAGAAATGGAAAGATGCTCCACATGTAATAGAACTTTCAGGAATGTTGATGAGCTATGTCAACACCAAAATGATTCTGGTCATCTCGAATTAAAACAAACACCGCAAGGGCCGGGATATGTGTGCTGGAAGAAAGGCTGTAACCGATATTTTGAAGCCGCTCACGCTCTACAAAACCATTTCCGTGAGGCTCACGCTCGAAACTCAATTGCTAATATGTCGGTTTCAGAAAAACATGTATATAAATACCGGTGTAATCAATGTAGTCTTGCCTTTAAAACAATTGAAAAACTTCAATTACATTCTCAATATCATGTCATTCGCGATGCAACCAAATGTGTTCTATGTGGACGAAGCTTTAGATCCGTATTAGCTCTTCAGAAACATTTGGAAACTTCTCACTCCGAATTAACTGAAGAGGAATTAACAACTTTTAAGCGTAATATTGCTTCAAACCCACTGTTACAATCGGGTCTCGGAACAGCTTTAGATGCTGCAACTGCAGAGCTTTTACGTAAAGAAACACTTAGAACACCAGAAGACGATATGGCCGAAATGGAGGATAGAGATTCAAGTGCAACAGCGGCTGATGAGTCTGGACATAATGACGCTGAGAATTCAGATGATTCTATAATTTACAAAGATCAACAGTTCCTAGAAGATTATTTAAATTCACAGGCGATGGCTGAAGATTCTTATAATGATCCTAATAGAAAATATAAATGCCACCGTTGTAAAGTGGCTTTTACTAGACAGTCATACTTAACTGCTCATAATAAAACACTACTTCATCGAAAAGGTGAGAAGCTAACATATCCAATGGAAAAATATCTTGATCCCAATCGACCATTTAAATGTGATGTATGCAAAGAATCTTTTACACAAAAAAATATTCTTCTTGTTCATTACAACAGTGTTAGTCATTTGCATAAATTAAAACGAGCAATGCAGGAACAACAAAATAATAACAATCAACCTGTCTCACCAGGCGCTGGCTCGGCCCCATCGAACCTCACGCTAACACCCAAGAGTACATCTAGTGAAGAAGATGACCGAAAAAGATACAAGTGCAATATTTGCAAAGTCGCCTACACTCAGGGTAGTACATTAGACATACACATGAGGTCAGTTTTACATCAAACGCGAGCTGGGAAGTTGCAAGAATTGGCTGCGGCTGGGCATGTGGACTTGTCACGGCCACTTGTAGAACAACCAGACAGGACGGACCCTTCGAAAATCTTACAAGACGTATTGTCGCCGAAAAACACATCCCCATCTTCAACAAGCAGCGGGTGTCCGCGTTCGTCACCCCCCGCCCGACCCAGTAGCCCACGGTCCCCTCGCACAGGTAGCGCCGCATGCGATCGTTGCCACGCGTCATTCCCGTCCGGGGAACTATTAGACGCACATCGCACGACATCTTGCCCGTTCGGCGATGCGTCGACGCACTCGCCGTTAGCTGATGCAGAGGCAGCTGCTTTTGACGAAATGGTCGCAAAGGGTAATCCGCCCAAACGAAATCCACAAATGTATAAACAATTATTAGAGACTTTTGGATTTGACCTCGTCATGCAATACAATGAAAACCAACGTCGCAAAATGCAAGAAGAGCGCGAAATGGCGAGAGCTCCGAGTCCTCCGCCTCCACCACCAGAGGAAAAGCCTCCCGATAGTGAAATTAAATCCACGTGCCAACATTGCAATAAAGAGTTTTCGAGTGTATTTGTGTTAAAAACGCACTGTGAAGAAGTGCATAAAGATAAAGTGCCGTTAGAGTTTTTAGAACAGTTCGCGGAACAATTCAAATCTGAATATGAGAGGAAATCTGGTGCACCGAACTCACCACGAGCGGCGTCTCCCGCACCTCAAAGCGAACGGTCCTCTTCACCACGTGCTGATGGTGCCGGCAGTGTCAATTGCGAAACACCAAATGGATCTGGAGAGGCTCAAGCTGGAGCTATTCTGGCAGCGCAAGTTCAAGAAATGCAAGCAGCGCTTAACATGCTTCAGCTTCAGCAGCAACTTGGGCAACTGCATCCGATGGTAGCTCAGATGCTATCGTTAGGTCTCCCACTTGGATTAAATATGGGCGCACTTGCTGCTATGAATCTACAACCACCTCTTGTGCCACTGATGCTGCCTCCACCACCATTTGATTCTATGCCCTTTTCTGGTCATGATGCACAGATGAAACAACAGCAATTATTGCAACAACAACAGCAGGCTAACGCTGCATCTGGTCAGAAACGAGCCCGTACACGCATCACCGATGATCAACTAAAAATATTGCGAGCACATTTTGATATCAACAATTCACCAAGTGATGAAGCTATTGCAAAAATGGCTAAAACATCTGGCTTAGCAACTAAAGTGATCAAGCATTGGTTCCGTAATACTCTATTTAAAGAAAGACAAAGAAACAAGGATTCTCCTTATAACTTTAATAATCCTCCATCCACAACACTCAATTTAGAGGAATATGAAAAAACTGGTGAGGCCAAAGTCACTCCACTAGACTCGTCAGCAAGTTCTGATGAAGGTAAACCACCACCTGAAAAGAAGCTTAAAACTGAAGATGATATGTCTCTTAATAATAGTCATCATGAAGTCAAGTCAGAACCAAGCGATGAACCTACAATAGAAGACAAATACTTATCTTATGATGACCGTCATCAAGAGGACAAGAGCTTTATATTCCCAGTTCCATCTCATAGTCCCCATTCGACTATCGGGAACTCTGACCATCATATAAATATCTCGAGACCGTCAACTCCCACACATTTATCACTGAATTCGCTTATACAATCACAATTAGATTCTATACCAGCGACAAGTATACCGCAACCACATCCATCAATGTTGCCACCGAAATTAAATCCAAATTTCACGTCCCCAAACTCCGCGCCCCCGAACGTCCTACCTTTGACCCCAAATCGGAGCCTAAGTCCTGGGAGAGGACCGGCCGATTTCGGACTTTCCGGGGGCAACTCGAACGGATCCAACAGCTCGGGGTCTTCTGGCAAACGCGCCAACAGAACTAGATTCACAGATTATCAGATTAAAGTATTACAAGAATTCTTTGAAAATAATGCTTATCCAAAAGACGATGATCTCGAATATCTATCTAAATTACTTGGACTCAGTCCTAGAGTAATTGTTGTTTGGTTTCAAAATGCAAGACAAAAAGCCAGAAAAGTTTATGAAAATCAACCTGCTGCAGAGCCACCTACTGGAGCTGCGGACGATGCCAACAGATTTCAACGTACACCAGGTCTGAACTATCAATGTAAGAAATGTCAACTTGTTTTTCAAAGATATTACGAATTAATAAGACATCAAAAAACTCACTGTTTTAAGGAAGAAGATGCTAAGCGGTCAGCCCAAGCACAAGCTGCTGCTGCTCAAGTTGCAGCGACCCTAAGTAGCGAAGATTCGAATTCAAGCACAGTTGATCATCATGGTCCTCACGTGGCTGTGTCACCAGCGCCGCCGCGTACTCCAACACCAGCTGCACCAAATTATCCTGTTTCCCCAGCGCCAAGTACGCCCCATACTCCAGTAACACCTATGACCCCTTTATCTCATGTTGTACCCCGAGAGGAGAAAGATGGAAACTTCCAATGCGATAAATGTAACTTAGTTTTTCCACGCTTTGATCTTTGGCGTGAACATCAATTGGTTCACATTATGAACCCTAATCTTTTTCCCACCTATGCACCTGATTCCCCTTTTGGAATATTACAACAACATGCTCAGCTACAACAATTGAATGCTAGTCTTGGTGGAGACGATGCTCGACATCCTTTAGTTGCAGCACTAAATCAACAAGCAGCTAAAAGAAAATTTGACGAGTATGAAGAAATCGATACAGGGGAACAACCAAAAGATAAGCGGCTAAGAACAACTATATTGCCGGAACAGCTAGATTATCTGTATCAGAAATATCAAATTGAGTCCAACCCATCTCGAAAAATGCTAGAAAACATTGCACGTGAAGTTGGTTTAAAAAAACGTGTTGTACAAGTATGGTTCCAAAATACAAGAGCGCGTGAAAGAAAAGGACAATTCCGTGCTCATGCACAAGTTATAAATAAACGCTGTCCATTTTGTCCAGCATTATTTAAAGTTAAAAGTGCACTCGAGAGCCATTTAAGCACAAAACATGCTGACCAATGTGCACGAGGAGAGATAAATGTTGACGCTTTACCTGACGAAGAGTTAAGCACTGAATCAACGCCAAGTTTTGGATCCCAACAAAGTGACAGACAGCAAAATTTTTCGCAAACGGGGGCCCCTATGTTGCCCCCTATATTCCCTCCTTTTCATTCGGACATGGAGAAGTTTATTAAGCAATATAGCGAAGAATCTATGAAGCGATACGTCAGCGAACTTCAAGCACATGCTGTCGCACAACAAAACGGCAATAGCGACCAAAATGAGAGACCTGAAGGTGGCAAAACTGAAATTCCTCTAGATCTGAGCAAACCTGTAGACTTATCGCGACCTGGATCTGATGCTGATGAAAGATCAGATACCGCTTCAGAAACAATGGAATTTTACGAAGAAGATGAACCTAGTTCGCCTATTCCTGGACAGCAGCATCCTCGATCTCAAGGTAAACGATTCCGAACGCAAATGTCTTCACTACAAGTAAAAATAATGAAATCTTTATTCAATGATTATAAAACACCAACTATGGCTGAATGTGAAGCTCTTGGTCGTGAAATCGGTCTACCCAAAAGAGTTGTGCAAGTATGGTTTCAAAACGCACGTGCAAAAGAGAAAAAGGCACGCCTAGCAGCTGGGTTGACAGAAATATCAGATGCACCACCACCAGATGAGTGTCGCGTTTGTGATTTTAAATATAGTCACAAATATTCCGTGCAAGATCATGTGTTCACGCGTGGCCACATTGCCACTGTCAGGGCCCGACTGGAAAGTAGTGCTATGACTGGAGATGAAGGAACACTCGCCCTGATGCAGATGGCGGCTCGACTGGAGAGTGGCGGCCTCAGCGGCAGCGGGGATCTCCACAACGCTTTCCTGCGCCCACAACTCGCTGGCAATGGTGAGTGTACGACTTGA
Protein Sequence: MVICLSSDHKEPIDQKPELTHEQKMMXXXXXXXXXXXXXXXXXXXXXXXXXFTKTEREEERERERELDTPGTHSCPYCNFSCNSEIRLHAHVATTHGDSSRHFMCPLCQDAFKDRTALERHVMQIHSVNSEGLQRLLLLVDQSHWLNGGNQAQRDETRQQEDEREISSPRSEGSADGEMERCSTCNRTFRNVDELCQHQNDSGHLELKQTPQGPGYVCWKKGCNRYFEAAHALQNHFREAHARNSIANMSVSEKHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRDATKCVLCGRSFRSVLALQKHLETSHSELTEEELTTFKRNIASNPLLQSGLGTALDAATAELLRKETLRTPEDDMAEMEDRDSSATAADESGHNDAENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNQPVSPGAGSAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSTLDIHMRSVLHQTRAGKLQELAAAGHVDLSRPLVEQPDRTDPSKILQDVLSPKNTSPSSTSSGCPRSSPPARPSSPRSPRTGSAACDRCHASFPSGELLDAHRTTSCPFGDASTHSPLADAEAAAFDEMVAKGNPPKRNPQMYKQLLETFGFDLVMQYNENQRRKMQEEREMARAPSPPPPPPEEKPPDSEIKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYERKSGAPNSPRAASPAPQSERSSSPRADGAGSVNCETPNGSGEAQAGAILAAQVQEMQAALNMLQLQQQLGQLHPMVAQMLSLGLPLGLNMGALAAMNLQPPLVPLMLPPPPFDSMPFSGHDAQMKQQQLLQQQQQANAASGQKRARTRITDDQLKILRAHFDINNSPSDEAIAKMAKTSGLATKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLDSSASSDEGKPPPEKKLKTEDDMSLNNSHHEVKSEPSDEPTIEDKYLSYDDRHQEDKSFIFPVPSHSPHSTIGNSDHHINISRPSTPTHLSLNSLIQSQLDSIPATSIPQPHPSMLPPKLNPNFTSPNSAPPNVLPLTPNRSLSPGRGPADFGLSGGNSNGSNSSGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAAEPPTGAADDANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSTVDHHGPHVAVSPAPPRTPTPAAPNYPVSPAPSTPHTPVTPMTPLSHVVPREEKDGNFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYAPDSPFGILQQHAQLQQLNASLGGDDARHPLVAALNQQAAKRKFDEYEEIDTGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINVDALPDEELSTESTPSFGSQQSDRQQNFSQTGAPMLPPIFPPFHSDMEKFIKQYSEESMKRYVSELQAHAVAQQNGNSDQNERPEGGKTEIPLDLSKPVDLSRPGSDADERSDTASETMEFYEEDEPSSPIPGQQHPRSQGKRFRTQMSSLQVKIMKSLFNDYKTPTMAECEALGREIGLPKRVVQVWFQNARAKEKKARLAAGLTEISDAPPPDECRVCDFKYSHKYSVQDHVFTRGHIATVRARLESSAMTGDEGTLALMQMAARLESGGLSGSGDLHNAFLRPQLAGNGECTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01452160; iTF_01494885; iTF_01495287; iTF_00923990; iTF_00923438; iTF_01451293; iTF_01451790;
90% Identity: iTF_01451293;
80% Identity: iTF_01452160;