Basic Information

Insect: Tinea trinotella
Gene Symbol: Hr39
Assembly: GCA_905220615.1
Location: HG992312.1:12320043-12332694[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.1 1.1e+03 -1.0 4.7 28 179 77 230 66 260 0.51

2 4 0.3 3.3e+03 -2.6 4.8 50 162 240 321 216 343 0.44

3 4 2.9e-08 0.00031 20.5 0.1 1 21 456 476 456 489 0.91

4 4 5.7e-64 6.1e-60 204.0 0.0 156 408 509 773 483 773 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.1	1.1e+03	-1.0	4.7	28	179	77	230	66	260	0.51
2	4	0.3	3.3e+03	-2.6	4.8	50	162	240	321	216	343	0.44
3	4	2.9e-08	0.00031	20.5	0.1	1	21	456	476	456	489	0.91
4	4	5.7e-64	6.1e-60	204.0	0.0	156	408	509	773	483	773	0.84

Sequence Information

Coding Sequence: ATGGCGAGTGAGGGTGAGGCTGTCAAAATTGAAGGTGGCCATGTCTCTGTAACTACTATCAGTATGTCTGGCAATGAAACTAATAACGGTCAATTTTCGTATAGTTCGAGTGGTGTCCGCATCAGTGTGTCATCGGAGCCACCACTTCACGACGAAGACTCTACTGATGCCGAATTGTCCAAGATTGATTTTGCACAACATCAATACGAGGTTAATATGAGAAATAAGAAAAAGCGTCCGTCAAGTGGTGCCCAATGTAGTGAAACACTATCAGCGAGCGAAAGAGAGAGACGTATGTCGTGGGAGGGAGAGCTGTCAGATTCAGAAATGGTTATTGATACTAGTGTCAGTAATGACGACAACAGCAATTCATTTGACTTACAATCGTCGAGGGACTCCATAGACACACTGAGGAATGTCACAATAAAAACTGAGCCCATGAAGATGGAGAATCGTTTGGATGGCTATCAGAGTTTGGATGACCAACATGTTTTGGATCTCAATTATAATACGTCATCGCATCCATTGCAAGCGCATCAACGTAGTCATAGTATGAATAGGATATCAGTTGTGAAAGATAACACGTCATTATTTTCATTGCGGCCTTCCTCACCGACATCGAGCGCCAAATCATTAGTACTAAATTCAGAAGCAAACGTACCAACGTCAATATCGGAAGTGCAAAATTTAACTATAAAAAAGGAAAACAGTGTACTTCAAACACAACTAACTGACGTGAAATGTGAACTATCAACATCGATGGGATTGGATAAATTATCGGGAACGTTACATGGCTCACCTCTGATTGGTCGATTACCACGTGTACTGTCAAGTGCTAGTACTGATTCAGCTGTACATTCCATGTATACACATAGTGTATACAGCAGTCCATCGGCGAGTCCCAGAGCATCACGTCACTATACTCCATCCCTTTCGCGCAACAACAGTGACGCATCGCACTCTTCCTGTTACTCATACAGTTCGGAATTCTCACCCACGCATTCGCCTGTACAGGGTCGTCATCCTCACGGCGTGATATACAGGGATGCAGCCTGTGTTTATCCTCCATCACCAGCTCACGAAGATGATGTAGACCCCAGCGATGATAGGTATCACCATCATCAAGGAATCAGTAGACAACAACTAATTAATAGCCCCTGTCCTATATGTGGAGACAAGATAAGCGGTTTTCACTACGGAATATTTTCATGTGAATCATGCAAAGGTTTCTTCAAGAGGACTGTGCAGAATCGCAAGAATTACATGTGCTTAAGAGGTGGTAATTGCCCAGTCACTGTGACTACTAGAAAGAAATGTCCCGCCTGTCGATTCGAAAAGTGTCTTACGTGCGGAATGAAATTAGAAGCAATAAGAGAAGATCGTACTCGTGGTGGCAGATCAACTTATCAGTGCTCGTATACGTTATCTGGCGCTGCTTCTACTGGCTCATTGCTGTCAGCTCATGCGACAGGCACGTTGAGGCATGCATCAAGTCTTACTTCGGTAAATGGCCCTGGCTCATACAACAGTAGAGGTGAGGCAAGTAACAGACTCACACCAGAAGTACCACCTTTATTACAGGAAATAATGGACGTAGAACATTTATGGCAATACAATGAATCTGAATTAACCCGGCTGGGCAAATCAACGGGCAGCCCTTCCGCAAACCCCTTCCTAGCCGCCAGTGGGATTACAGCGCAAAATTCTAGTCCAGACTTCCTCGCAGACCTCTGCAACATAGCTGATCATAGACTCTATAAGATTGTCAAATGGTGTAAGAGTTTGCCGCTCTTCAAGAATATTTCCATTGACGATCAAATCTGTTTATTAATAAATAGTTGGTGCGAATTACTTGTGCTGTCGTGTTGTTATCGGGGAGTTGCCACCCCTGGAGTGGTGGGGGTGGGGGCTGGCGGGGGGCTTACATTGCAACAAAGTGCCAAATTAGGTTTAACACCGTGCATAGAACGTATGTTGAGCTTCACGGATCATTTGAGAAGGTTAAGGGTAGACAGATACGAGTACGTGGCACTCAAAGTCATCGTTCTGCTCACATCAGATGCATCCGAGCTTCGTGAAACGGAAAAAGTTCGTGCGTCCCAGGAGAAGGCTCTGGCAGCTTTACAGACATACACGGCAACACATTCACCAGACACACCGGCGAAGTTTGGCGAACTCCTACTACGGATACCCGAGCTGCAACGAACCTGCCAGTTCTTCATGCAAGTCGGCAAAGAAATGTTGAATCCATCAAACAAGAATAAAGACAACGATGGTCCAAGCTTCAATCTTTTAATGGAACTCCTAAGAGGTGATCACTGA
Protein Sequence: MASEGEAVKIEGGHVSVTTISMSGNETNNGQFSYSSSGVRISVSSEPPLHDEDSTDAELSKIDFAQHQYEVNMRNKKKRPSSGAQCSETLSASERERRMSWEGELSDSEMVIDTSVSNDDNSNSFDLQSSRDSIDTLRNVTIKTEPMKMENRLDGYQSLDDQHVLDLNYNTSSHPLQAHQRSHSMNRISVVKDNTSLFSLRPSSPTSSAKSLVLNSEANVPTSISEVQNLTIKKENSVLQTQLTDVKCELSTSMGLDKLSGTLHGSPLIGRLPRVLSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHGVIYRDAACVYPPSPAHEDDVDPSDDRYHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVTTRKKCPACRFEKCLTCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHATGTLRHASSLTSVNGPGSYNSRGEASNRLTPEVPPLLQEIMDVEHLWQYNESELTRLGKSTGSPSANPFLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVATPGVVGVGAGGGLTLQQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDASELRETEKVRASQEKALAALQTYTATHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPSNKNKDNDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01386822;
90% Identity: iTF_01453355;
80% Identity: iTF_01452450;