Tpel004692.1
Basic Information
- Insect
- Tinea pellionella
- Gene Symbol
- ZEB2
- Assembly
- GCA_948150575.1
- Location
- OX411257.1:8651598-8653163[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0039 0.22 12.1 0.2 2 23 140 161 139 161 0.97 2 13 8.2e-06 0.00046 20.5 0.6 1 23 167 189 167 189 0.97 3 13 0.062 3.4 8.3 0.5 2 23 204 225 203 225 0.95 4 13 7.4e-05 0.0041 17.5 1.4 1 23 231 254 231 254 0.90 5 13 1.2e-05 0.00064 20.0 0.4 1 23 261 283 261 283 0.97 6 13 0.00045 0.025 15.0 3.2 1 21 289 309 289 311 0.93 7 13 0.0043 0.24 11.9 5.8 1 23 317 339 317 339 0.95 8 13 0.00058 0.032 14.7 4.9 1 23 345 367 345 367 0.98 9 13 1.9 1.1e+02 3.6 1.8 2 23 373 395 372 395 0.93 10 13 0.0004 0.022 15.2 0.9 5 23 401 419 399 419 0.97 11 13 0.0058 0.32 11.5 0.4 1 22 425 446 425 448 0.90 12 13 0.002 0.11 13.0 0.1 1 23 454 479 454 479 0.95 13 13 0.0012 0.068 13.6 7.1 1 23 485 508 485 508 0.95
Sequence Information
- Coding Sequence
- ATGGAGCCGAAAATATGTCGAACTTGTCTTCGTGATAATGGGTGTATTTCTTTATTTAGCGAATCCGATGAGACAAAAATTAGTGCCAAAATAATGCGTCTGACCGGTATCATAATAGATAAATATGACGGCCTACCCGCTCATATCTGCACGTCTTGCGAATCTGAACTGAATGTAGCTTGTAATTATATAAACAAATGCCAAGAGTCCGAGAAGATTTTACGCGAGAAGGATGACCCCATCGTCGACTTTGACAATAAACGCATCATAATTAAAGTTGAACAAACGGATGATGGTGATTTATTGCAGTCCTCTGATGAACGGGACGATTCAGAGGAACCACCTGTAAAAAAAGTGAAGCTGGAAACTAAAAGAAAGTCTTTGCAATCTCGTAGAAAAAGAGTAGAATCAAAAATAACATGTGAATTATGCGGACAGAGGGTGGTTTGCCAATCTGCATTAGCGGTACACATGAGAGTGCACACGGGCGAGAAGCCATTCGAATGTGAAAGATGCGATAAGAAGTTCGCCACCAAGTCACAAGTTAAGATACATCTCAATGCGCATCTCAAAATACGTGACAAACTAAAGAAACGACCCAAGAAGATCGAATGCCTCCAATGCGGTAAACTATGCCAGGGTCCCTCCGCATTGAAAACACATTCACTGTCGCACAGCGGAGAGAGACCCTTCCAGTGTACAAAATGTCCTAAACAATTCAGATACCAGGGCGGATTGAAGAATCACTTCGAGGCTAACCACTGCGTGAGAGAGAGAAAGTACATATGCGACTACTGTGGTGTTAAGTTCTATTCAAAAGCTACGCTCATTCGTCACCTCTATATACATACTGATTTCAAACCATATTTGTGCACCCGCTGCCCGCAGAGGTTCAGGCAGCAGTCTGCGCTCATCAGACACACGAGATGTCACACGGGCGAGAGGCCGTACTCGTGTAAAACATGCGGGAAGAGCTTCCCTTGCAACAGCAGCTTACGACATCACAGCGTGAAGCACAGCGATGAAGCTAATTATAAATGTGAACAATGCGGAAAGATGTTTAAATCTAAAGAGAGACTTCGTTGTCACACAAAAGTACACAATCATAAGAGTTTAGTGTGCAACTGTTGCGGCATGCAGTTCACATGGAAGGGGTGTCTGGACGCTCATGTGAGACGGGTGCATTCCGAGAGATCCGGTCATTGTGAAGTATGCTTCAAACAGGTCTCCGATCTGGAAGTGCACATGAGGAAACACACGGGAGAGAAGCCGTATCCGTGTGACGTGTGCGACAGTGCGTTCAGCACGGCCTTGAGCCTCAAACTACATAAGACTTTCAAGCACACGGAAGGTGGAAAATATGAGTGCGCCTATAGCGGTTGTGATAAAACATTCCCCATTCCCTCGATGTTGGAATACCACGTATTGAAATATCACACACACAGCACTCCTCACGTCTGCAAACATTGTAATAAAGGTTTCTTCCGCTTGTGTGATCTCAATAGACATTTGAAAGCAAATCATTCTATCTTAGAAGATAATATAAAAAATTCTCCAAAAGATTAA
- Protein Sequence
- MEPKICRTCLRDNGCISLFSESDETKISAKIMRLTGIIIDKYDGLPAHICTSCESELNVACNYINKCQESEKILREKDDPIVDFDNKRIIIKVEQTDDGDLLQSSDERDDSEEPPVKKVKLETKRKSLQSRRKRVESKITCELCGQRVVCQSALAVHMRVHTGEKPFECERCDKKFATKSQVKIHLNAHLKIRDKLKKRPKKIECLQCGKLCQGPSALKTHSLSHSGERPFQCTKCPKQFRYQGGLKNHFEANHCVRERKYICDYCGVKFYSKATLIRHLYIHTDFKPYLCTRCPQRFRQQSALIRHTRCHTGERPYSCKTCGKSFPCNSSLRHHSVKHSDEANYKCEQCGKMFKSKERLRCHTKVHNHKSLVCNCCGMQFTWKGCLDAHVRRVHSERSGHCEVCFKQVSDLEVHMRKHTGEKPYPCDVCDSAFSTALSLKLHKTFKHTEGGKYECAYSGCDKTFPIPSMLEYHVLKYHTHSTPHVCKHCNKGFFRLCDLNRHLKANHSILEDNIKNSPKD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01453475;
- 90% Identity
- -
- 80% Identity
- -