Tshe048874.1
Basic Information
- Insect
- Timema shepardi
- Gene Symbol
- L
- Assembly
- GCA_902151425.1
- Location
- CABFVX010007717.1:21617-25965[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.038 10 9.2 0.2 3 23 12 32 11 32 0.98 2 17 0.0022 0.59 13.1 0.5 2 23 69 90 68 90 0.95 3 17 0.012 3.3 10.7 0.2 3 23 100 121 98 121 0.93 4 17 0.018 4.9 10.2 0.3 1 23 126 149 126 149 0.92 5 17 7.4 2e+03 2.0 0.4 1 23 156 182 156 183 0.87 6 17 1.6 4.5e+02 4.0 2.4 1 23 200 222 200 222 0.94 7 17 0.061 17 8.5 5.3 1 23 226 248 226 249 0.95 8 17 0.41 1.1e+02 5.9 1.5 3 23 323 345 322 346 0.93 9 17 0.0027 0.73 12.8 4.6 2 23 363 384 362 384 0.96 10 17 0.44 1.2e+02 5.8 0.5 1 23 394 416 394 416 0.94 11 17 2.5 6.9e+02 3.4 0.6 2 23 424 445 423 445 0.95 12 17 3.6 9.7e+02 3.0 0.1 1 13 494 506 494 510 0.87 13 17 0.00044 0.12 15.3 0.0 1 23 542 565 542 565 0.97 14 17 0.14 38 7.4 0.2 1 23 569 591 569 591 0.97 15 17 0.13 37 7.4 1.4 1 23 599 621 599 621 0.96 16 17 0.0032 0.87 12.6 0.2 1 23 629 651 629 651 0.97 17 17 0.52 1.4e+02 5.6 1.7 1 23 658 680 658 680 0.96
Sequence Information
- Coding Sequence
- ATGAATCAATACGACCAGCCGGGCACCCTTCTATGCAACCAATGTGGTGCGGCCTTGCCAGACTTCGAGTCGTTCCGCACCCATCTCAAGTCTCACCTGGAGGAGGCGGGAGGGCTCCGGGGTCTACTTGGGGGCGGGGGCACGGACCTGCTGGCTATGCTCGCCGCCTCCTCCTCGGAACAACGCGTCAAGAGCCCCGCCCTGCCCTGCCCCCACTGTGGCGCCAAGTTCTCCGACCCGGAGGACCATCAACAGCACCTCGCCAGTCACTTCCTGGCCACGGCGACCGAGTACGGCTGCCAGAGCTGCCTCAAGCTGTTCTCCAAGCCCGACGAGCTTCAGAAACACCTCATGGACATCCACGCGCACCATCTCTACCGCTGTTCCCTGTGCAAGGAGATGTTCGACTCCAAGGTGGCCATACAGGTCCACTTCGCTGTGAAGCACAGCAACGAATGCAAGCTGTACCGCTGCACAGCCTGCCCGTTATCCTCAGCAGTGTTCCGCTCGGAGATGGACTTCGGTCTTCACGTCCGGACAATCCACCACCACCCCCCGTCGCCGACCAAACTCCCAGCCTCCGCTCCTCAGCAGCAGTTCCGCTGCTTGTTCTGCCGCCTCAGCTTCCCGACTGAGCACGACATGCAGTTTCACCTGACGGTCCACTCCAAGCAATTCCACTGTCCTTTCTGTCAAGAGGGCTTTCATGTGGAGTTCTTGTTGGACAAACACATGCAGACTCACCATACCACGCAGGTCCTGAGCAGCAGCTCATCGAATGGCGTGGACAACCCGAGTCAACAGAAATCCCCCAAGAGCAAACCTCCAAGTGGCGGCAACCCTTCAAACTCCATGGCGACTATCGGAAATAACAATTCTTCTCTCAACCTTAACAACAACTCCTCTAGAGGCTCCAGCTCTGACAATGGCGTCGCTTCCAAGATACCCGAAAACTCCAAGAACTGCTGCGACATCTGTGACCGGCGTGACTTCGCCGGCGAGTCCGAGCTGACGGCGCACCGGAAGCTGGTCCACCACGTGAAAACCGCTGGCGCCGGTGGGGGTAAGAACGGCGCCGTCAGTCTCCACTGCGCCTACTGCAGCGAGAACTGCAAGTCCAGGACGGAACTGGAGAACCACATGAAGACTCACTCCCAGGGCAGCGGAGGTTCGGGGAAACACAAGTGCAACATCTGCGACGAGCTGTGTCCGTCGGCAGCCATCTTGGCCGAGCACAAGCTGACTCACTGCAAGGTGGTCTCCGGGAGCGTGTGCACGCAGTGCAAGTCTAACCTTGTCAGTGAGGAGCAGTTCTACTCGCACCTACAGCAGCACGGAGGGGGCGGGGCGAACAACTCTACCCACAGCCCTCAACAGGTCGCCTTACCGACGCCATGCGTCGTCTGCAGACAGACGCTGATATCCGACATTGAGGTCCGCATGCACGCCCGGTTCCACCTGAAGAACTCCGAGCCGACCTATCAGTGCTTCCTGTGCCTGAAACAGTTCGAGTCCCAAAACCTGGTGGTGGCCAACGGAGGCCCCCAGGCCTCCACCTACGTGTGCAAGGAGTGCTACCACTGCCACAGTAAGACGTCGCCGTCCCCGGGCCAGGAGCAAGCGTTTAGATGTCCAGAGTGCCAGGTCAAGTTCGAGGCGAGCTCTGCGCTGGAGGCTCATTTAGTGACCGTCCACAAGAAAACCTACCAGTGCATCAAGTGCCAGATAAGTTTCGAGACTGAACGCGAGATCCAGCTTCACGTGGCCACCCACCTGCTGACTGAGGGCAGCAGCCACGAGTGCCACCTGTGTCGCCGCCTGCTGTCCACGCCGCTCAAGTTGCAGGCCCACCTCATAGAGCACACCTTCGCGGGCTGCGGCAGCTTCACCTGCTACCTGTGCAGCGCGGTCTTCACGGCGTCCCAAGGCCTGCAGCAGCACATGCTAGAACACGGCCTGGCGGCCAGGCCTTACGACTGCTCCAGGTGTAGCCTGCGGTTCTTCTTCAGGGCGGAGCTGGACAACCACAGCTACACCCACCTGGAGGAGGCTATGGTCGAAGGTTCCGGGGCGCTAATAGATGGAGGCGACCTGGCGTCCAAGGTAGGTGGATATCTACACCCACCTGGAGGAGGCTATGGTCGAAGGTTCCGGGGCGCTAATAGATGGAGGCGACCTGGCTACCAAGGTAGGTGGATATCTACACCCACCTGGAGGAGGCTATGGTCGAAGGTTCCGGGGCGCTAA
- Protein Sequence
- MNQYDQPGTLLCNQCGAALPDFESFRTHLKSHLEEAGGLRGLLGGGGTDLLAMLAASSSEQRVKSPALPCPHCGAKFSDPEDHQQHLASHFLATATEYGCQSCLKLFSKPDELQKHLMDIHAHHLYRCSLCKEMFDSKVAIQVHFAVKHSNECKLYRCTACPLSSAVFRSEMDFGLHVRTIHHHPPSPTKLPASAPQQQFRCLFCRLSFPTEHDMQFHLTVHSKQFHCPFCQEGFHVEFLLDKHMQTHHTTQVLSSSSSNGVDNPSQQKSPKSKPPSGGNPSNSMATIGNNNSSLNLNNNSSRGSSSDNGVASKIPENSKNCCDICDRRDFAGESELTAHRKLVHHVKTAGAGGGKNGAVSLHCAYCSENCKSRTELENHMKTHSQGSGGSGKHKCNICDELCPSAAILAEHKLTHCKVVSGSVCTQCKSNLVSEEQFYSHLQQHGGGGANNSTHSPQQVALPTPCVVCRQTLISDIEVRMHARFHLKNSEPTYQCFLCLKQFESQNLVVANGGPQASTYVCKECYHCHSKTSPSPGQEQAFRCPECQVKFEASSALEAHLVTVHKKTYQCIKCQISFETEREIQLHVATHLLTEGSSHECHLCRRLLSTPLKLQAHLIEHTFAGCGSFTCYLCSAVFTASQGLQQHMLEHGLAARPYDCSRCSLRFFFRAELDNHSYTHLEEAMVEGSGALIDGGDLASKVGGYLHPPGGGYGRRFRGANRWRRPGYQGRWISTPTWRRLWSKVPGR*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01445204;
- 90% Identity
- iTF_01445204;
- 80% Identity
- -