Tshe003724.1
Basic Information
- Insect
- Timema shepardi
- Gene Symbol
- -
- Assembly
- GCA_902151425.1
- Location
- CABFVX010000162.1:13733-19965[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00019 0.053 16.4 2.6 1 23 301 323 301 323 0.96 2 12 0.00049 0.13 15.1 0.5 2 23 326 348 325 348 0.95 3 12 4.9e-06 0.0013 21.4 1.6 2 23 389 410 388 410 0.97 4 12 0.00046 0.12 15.2 0.2 1 23 416 438 416 438 0.95 5 12 0.00053 0.14 15.0 2.5 1 23 444 466 444 466 0.98 6 12 4.3e-05 0.012 18.4 3.2 1 23 472 494 472 494 0.98 7 12 0.0019 0.51 13.3 2.7 1 23 500 522 500 522 0.96 8 12 2.1e-06 0.00056 22.6 2.1 1 23 530 552 530 552 0.98 9 12 0.002 0.54 13.2 0.2 1 23 558 580 558 580 0.96 10 12 3.1e-05 0.0084 18.9 1.1 1 23 586 608 586 608 0.98 11 12 5.2e-06 0.0014 21.3 0.7 1 23 614 636 614 636 0.98 12 12 1.1e-05 0.0029 20.3 0.9 1 23 642 664 642 665 0.95
Sequence Information
- Coding Sequence
- ATGGCAAAGCTTATTGACCATTTAGCTGTTTTGAAGGATTTATGTCGATTATGTGCAGCTAAAACAACAGTTATAATGGGTCTTCACATATTTGGAAGTGAGGGTGACGTTAGacaattgtataaaaaaataactgctTGTTTGCCAGTGGAGatCGCTCCGACAGATAAACTACCCAAAATGGTCTGTCAAGATTGTGTTACTAAGCTAGATCTTTTGTTCGATTTCCGAGAGAAAAGTATTAAGACTGAAAGCTTACTATCGAGATTATTGAAGGAAAAGGAATCTCTTTCTATGATTGTGGTGgaAAACAATGGAGCGGTGATAACGGAAAATATTGAAGCCGAGCAGCAACTTCATCTTGAACAATGCCAACATGTGTTGaaacagcaacaacaacaacagttTGTTGATCTGAGTCGGCAAGAGGAGGTGTCCTTGTCCCAGCAGGACAACGACGTAGACGTTCAGTCCCTGGGCAGCGTGCAGGTGGAGTCTGAATCTCAGGGGGAAGAACGTGCTCCATCACATAACGTCTCCGAGGTGTCGACGAACGTCAAGTGTGAGCCGGATGTGTTGATCAAGGTGGAGGAGATGGCGAATCTCAACGCGCGGGACAGCGACATCGACACGGAGATCGAGAGCGACTCGGCGAGCGAAGACAGCGAGGGGAACGATGGGGAGGACCACCGGGCGAGCACCCCGCCGGGGGTGGAGCGGGAAGAGGGGGGTGACTATTCGGCTGAGGCGTCAACTAGTCAAGATTTGCAGGGGCTATCCAACTGCGAGGGCGCTGTCAACTCTTACGAAGGAGGAGACAGCTTCATGACACCCGCCACCAATGGTTTACTGCTCCTCTCGTGCCCTCAAAAGACCGAAGGACTGGAACAGGCGACATGGTTCTTTTGCAACATGTGCGGCAAATCCTTCGGTCAGCAGGAGGACTTCCACCTCCACTACGAGAGTCACTGCAACAAGTGCAACTCGTGTGGGGCCCTCTTCACCAACAAAGACGCACTGAAGGCTCACCGGAAGGAGATGCACCCACGGAAGAATGTCAAGCTTGAAAAGGAGATAACGCCGGTGGCGGCGGGCGCGAATGCCGGGAGGAAAGCGGTTCTGAGCTCCTCGGCGGCGGCCAGGAGGAAGAAGTGGGAGCCAAAAGTGTGTTCCGAGTGCGGAAAGCAGTACAGGACTAACTACAAGTTGTCGGAACACATGCGGAAGCACACAGGGGAGCGACCCTTCGCCTGCTCGTCTTGTCCCAAGTCTTTCCGATCCAAGATCGGGCTGGCGCAGCACGAGGCCAAACACACGGGGCAGTACGAGTTCTCGTGTAGCACCTGCGGGAAAGGCTTCCAGTGCAAGTCGTACCTCATCGTCCACCAGCGCGTGCACAGCAACCTTAAGCCGTATCCGTGCCCGACGTGCAGCCGGCACTTTAAGACGAAGCAGTCCCTTCTGGACCACCAGAACCGTCATCTGGGGGTCAAACCGTACCTTTGTGACACGTGTGGACGCCGGTTCATCACCAAGGGGCTATGCAAGTCGCACCAAAGGGTACATTCTGGGAAAGACAACAAGCAGTACCCGTGTATGGTGTGCCACAAGATGTTTGTGAGCAAGTCGTATCTCACCACACACCTGCGCATACATACAGGAGAGAAGCCCTACATGTGTGAGGTGTGCGGTAAGGGCTTCCTGACACGTGTGGACCTGCGCATTCACTCCACCATGCACACCGGTGAGAAGAGCTTTGTGTGCGAGTGGTGTGGGAAGGCATTCGCCCGCCGGGACGCTCTGCGCTGTCACCGGCGCAGCCACACGGGCGAGCGTCCTTATCGCTGTGACATCTGCGGGCAGTCGTTCACGCAATTCTCCCCGCTCACAATCCACAAGCGCCTGCATACAGGTGAACGCCCCTACCCTTGCGAGATATGTGGTAAGGCGTTCGTCTCGAGGTCGACCATGTCGGCGCACAGCAAGAAACACCATACTTAG
- Protein Sequence
- MAKLIDHLAVLKDLCRLCAAKTTVIMGLHIFGSEGDVRQLYKKITACLPVEIAPTDKLPKMVCQDCVTKLDLLFDFREKSIKTESLLSRLLKEKESLSMIVVENNGAVITENIEAEQQLHLEQCQHVLKQQQQQQFVDLSRQEEVSLSQQDNDVDVQSLGSVQVESESQGEERAPSHNVSEVSTNVKCEPDVLIKVEEMANLNARDSDIDTEIESDSASEDSEGNDGEDHRASTPPGVEREEGGDYSAEASTSQDLQGLSNCEGAVNSYEGGDSFMTPATNGLLLLSCPQKTEGLEQATWFFCNMCGKSFGQQEDFHLHYESHCNKCNSCGALFTNKDALKAHRKEMHPRKNVKLEKEITPVAAGANAGRKAVLSSSAAARRKKWEPKVCSECGKQYRTNYKLSEHMRKHTGERPFACSSCPKSFRSKIGLAQHEAKHTGQYEFSCSTCGKGFQCKSYLIVHQRVHSNLKPYPCPTCSRHFKTKQSLLDHQNRHLGVKPYLCDTCGRRFITKGLCKSHQRVHSGKDNKQYPCMVCHKMFVSKSYLTTHLRIHTGEKPYMCEVCGKGFLTRVDLRIHSTMHTGEKSFVCEWCGKAFARRDALRCHRRSHTGERPYRCDICGQSFTQFSPLTIHKRLHTGERPYPCEICGKAFVSRSTMSAHSKKHHT*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01449841; iTF_01448804; iTF_01447785; iTF_01445036; iTF_01446892; iTF_01445903;
- 90% Identity
- iTF_01446892;
- 80% Identity
- -