Tshe003740.1
Basic Information
- Insect
- Timema shepardi
- Gene Symbol
- Gzf1
- Assembly
- GCA_902151425.1
- Location
- CABFVX010000162.1:173865-179816[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 0.21 58 6.8 0.2 2 23 23 44 22 44 0.96 2 21 2.3e-05 0.0062 19.3 1.7 1 23 54 76 54 76 0.97 3 21 1.1e-05 0.0031 20.3 1.6 1 23 82 105 82 105 0.97 4 21 0.13 36 7.5 1.8 1 23 112 134 112 134 0.96 5 21 2.1e-05 0.0058 19.4 1.5 1 23 140 163 140 163 0.98 6 21 8.5e-05 0.023 17.5 0.9 1 23 168 190 168 190 0.98 7 21 1.2e-05 0.0034 20.1 3.8 1 23 198 220 198 220 0.97 8 21 3.2e-07 8.7e-05 25.1 0.4 1 23 226 248 226 248 0.98 9 21 8.1e-05 0.022 17.6 1.5 1 23 254 276 254 276 0.98 10 21 7.1e-07 0.00019 24.0 0.9 1 22 282 303 282 303 0.97 11 21 0.0066 1.8 11.6 1.2 1 23 358 381 358 381 0.95 12 21 3.8e-06 0.001 21.8 1.0 1 23 384 406 384 406 0.98 13 21 4.2e-05 0.011 18.5 2.6 1 23 412 434 412 434 0.98 14 21 0.47 1.3e+02 5.7 3.9 1 23 440 462 440 462 0.97 15 21 0.015 4 10.5 2.7 1 23 468 491 468 491 0.96 16 21 7.7e-05 0.021 17.6 0.5 1 23 496 518 496 518 0.98 17 21 2.8e-06 0.00077 22.1 0.6 1 23 528 550 528 550 0.97 18 21 0.00071 0.19 14.6 4.6 1 23 556 578 556 578 0.98 19 21 6.8e-07 0.00019 24.1 0.6 2 23 585 606 585 606 0.97 20 21 7.3e-06 0.002 20.9 3.9 1 23 612 634 612 634 0.98 21 21 2.5e-06 0.00067 22.4 0.8 1 23 640 662 640 662 0.98
Sequence Information
- Coding Sequence
- atgttaaataataacaaaaccgATGTCGGCGACTCGGTACTACCCTCGGATCTCTTACAGAAGAACAAGTGTCAACTGTGCAGACAAACATTCCTTCTCGAGTCGGAGTTGGCGGCTCACATCCTCAACCACGCGAAGGACCCTGGGACGAGTCCTCGGCACCCCTGCCCTACATGCGGCCAAGTTTTTCCCAAACGCTTCCTGATGAAGCGTCACTTGCGACGTCACGATGACGTCTGGCAGTACAAGTGCGACATCTGCTCCAAGTTCTACAAGTCTAAATACAGTTTAGACGCGCACATGAAGTGGTCACATTCGGGCGAGACAAAGAACCACTCGTGCTCTGTGTGCGGATACAGAGCCTACCACCTATCCGCGATAAGGCAGCACGAGAAGATACACACAGGCGTGTTTGATTACACCTGTGGAGATTGCGGCAGAGGATTCCACACAAAGACCATGTTGAAGTCGCACAGGATAACCGCTCATGACGACGAACCTTTCAAGTGCAATTACTGCGGTAAAATCTACCGTTCCAAGGCAAACCGTGACGAGCATGTGAAAATCCACGACCCGGACTATGTCCACGTTCACCAGTGTGAGCTGTGCGGGAAGACGTTCCACACCAAACCAGAGTTGAAGAAGCACCTGGCGAGACACAGAGGCGACGAGAAGTATGTCTGTGAGGAATGTGGTAAACCGTTCAAGTCCAAGACGACGCTTGTCAACCATACGCGCATACACAGCGGGGACAAACCTTACGTCTGCCTGCTCTGCAGGAAAGCCTTCACCACCTCCTTTTTCCTTAAAACCCACGTTCGCATTCATACTGGTGAGAAACCTTTCTCGTGCGAGATTTGTTCCAAGTCGTTTTCTCAGAAATCTTCCTTGACTGTGCATACCCGgacaGCCGGCATAATCCTTAATTCGTATCAAGACTTACACGATACAAACTTGGCGTGGAGGCCAGATCTTGGTTCGGCGTGGTCGCTAGAGCCCGCCTCTTCTGCGGCGACACAATCCCGCAAGGAGGACACTAAACCGGTGGTGTCGAATGACAGGGGAGGACAGTTTGCGTGCCAGTGGTGTGACAAACAGTGCATGAACGAATACATGATGAGGCGCCACATCAAAGGCGCCCACACTACATACAAATGCCAGTTGTGCGGCAAGGTGTACCCCCAGCGCCGCATGTTGACGCGTCACGCCAAGAGTCACACCGAGCTCAGACCTTTTTCCTGCGAGATCTGCGCCAGAAAGTTCAAGCAGATGTTCGAGTTGAGGAAGCACCAGAAAACCCACACGGGCAACAAGACGTTCGCCTGCCACATCTGCGACTTCTCCGCGTATTACAAATGTGTCTTGAGGGAGCACGTGAAGAAACACAGCAGAGACTTTGGCTATCACTGCGATGAGTGCGACAAAGGTTTCCACACCCCTCAGCAGGTGGACTCGCACAAGATAACCTACCACGGGGCCCAACCTTTCCAGTGCAACGTGTGCGGTAAAACCTACGCCGTGAAGAACAGGCTGAAGGTGCATAAACTGGTTCACAACCCTTCGTTCGTGGCAGAACGCAAGCACCAGTGCGAGGCGTGCGGTAAGACCTACAAGCGCGCCGGCGAGCTCGTGCGCCACATGAACCTTCACACGGGAGAGAACCGATACATGTGCAACGATTGTGGAAAGTGCATGACGAGCAAGTGTTCGCTCAGAGATCACGTAAAGATACACATGGGGGAGAGGCCAGCCGTGTGCGAGATCTGCGGGAAGGCGTTTGTCCGGCACGATTACCTCAAAGTTCATCTGCGCTCTCACACGGGGGAAAAGCCCTATTCCTGCGAGACCTGCAACAAGTCTTTTACCCAGCATTCGTCACTGGTTATTCACCGGCGCTACCATACGGGCCACAGGCCCTACGACTGCTCCGTGTGCAACAAAGGGTTTGTGTCTAAGACCTTGTTGAGGACGCACCAAAGAGTTCATAATCACGGAGTTCTCAATGCAAGATGA
- Protein Sequence
- MLNNNKTDVGDSVLPSDLLQKNKCQLCRQTFLLESELAAHILNHAKDPGTSPRHPCPTCGQVFPKRFLMKRHLRRHDDVWQYKCDICSKFYKSKYSLDAHMKWSHSGETKNHSCSVCGYRAYHLSAIRQHEKIHTGVFDYTCGDCGRGFHTKTMLKSHRITAHDDEPFKCNYCGKIYRSKANRDEHVKIHDPDYVHVHQCELCGKTFHTKPELKKHLARHRGDEKYVCEECGKPFKSKTTLVNHTRIHSGDKPYVCLLCRKAFTTSFFLKTHVRIHTGEKPFSCEICSKSFSQKSSLTVHTRTAGIILNSYQDLHDTNLAWRPDLGSAWSLEPASSAATQSRKEDTKPVVSNDRGGQFACQWCDKQCMNEYMMRRHIKGAHTTYKCQLCGKVYPQRRMLTRHAKSHTELRPFSCEICARKFKQMFELRKHQKTHTGNKTFACHICDFSAYYKCVLREHVKKHSRDFGYHCDECDKGFHTPQQVDSHKITYHGAQPFQCNVCGKTYAVKNRLKVHKLVHNPSFVAERKHQCEACGKTYKRAGELVRHMNLHTGENRYMCNDCGKCMTSKCSLRDHVKIHMGERPAVCEICGKAFVRHDYLKVHLRSHTGEKPYSCETCNKSFTQHSSLVIHRRYHTGHRPYDCSVCNKGFVSKTLLRTHQRVHNHGVLNAR*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01449807;
- 90% Identity
- iTF_01449807;
- 80% Identity
- -