Basic Information

Insect: Timema shepardi
Gene Symbol: -
Assembly: GCA_902151425.1
Location: CABFVX010000162.1:243767-252756[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 30 0.00036 0.097 15.6 0.1 2 23 11 32 10 32 0.96

2 30 0.00022 0.06 16.2 4.3 1 23 38 60 38 60 0.97

3 30 0.001 0.28 14.1 0.3 1 23 66 88 66 88 0.98

4 30 1.6e-07 4.4e-05 26.1 1.2 1 23 94 116 94 116 0.98

5 30 3.9e-05 0.01 18.6 5.2 1 23 121 143 121 143 0.98

6 30 1.2e-05 0.0033 20.2 0.6 1 23 152 174 152 174 0.98

7 30 2.6e-06 0.00071 22.3 0.2 1 23 180 202 180 202 0.98

8 30 5.2e-06 0.0014 21.3 0.8 1 23 208 230 208 230 0.98

9 30 4.5e-07 0.00012 24.7 3.3 1 23 236 258 236 258 0.97

10 30 0.0002 0.054 16.4 1.2 1 21 264 284 264 286 0.95

11 30 6.3e-05 0.017 17.9 2.1 2 23 329 350 328 350 0.96

12 30 0.0053 1.5 11.9 6.9 1 23 356 378 356 378 0.98

13 30 0.37 1e+02 6.1 2.7 1 23 384 406 384 406 0.93

14 30 0.0018 0.48 13.4 1.9 1 23 413 435 413 435 0.97

15 30 5e-06 0.0014 21.4 0.7 1 23 441 463 441 463 0.98

16 30 4.2e-06 0.0011 21.6 1.4 1 23 468 490 468 490 0.98

17 30 0.018 4.9 10.2 1.9 1 20 497 516 497 518 0.92

18 30 2e-06 0.00053 22.7 0.3 1 23 525 547 525 547 0.98

19 30 3.6e-05 0.0097 18.7 1.3 1 23 553 575 553 575 0.98

20 30 9.1e-06 0.0025 20.6 0.4 1 21 581 601 581 602 0.95

21 30 0.011 2.9 10.9 0.4 2 23 694 715 693 715 0.96

22 30 0.029 7.7 9.6 3.3 1 23 720 742 720 742 0.97

23 30 0.03 8.1 9.5 0.5 1 23 748 770 748 770 0.98

24 30 0.00029 0.078 15.8 1.3 2 23 777 798 776 798 0.97

25 30 0.52 1.4e+02 5.6 0.6 1 23 804 827 804 827 0.94

26 30 4.9e-06 0.0013 21.4 1.7 1 23 834 856 834 856 0.96

27 30 0.00033 0.089 15.7 0.2 1 23 861 883 861 883 0.96

28 30 9.7e-05 0.026 17.3 1.6 1 23 889 911 889 911 0.96

29 30 1.4e-06 0.00039 23.1 0.8 1 23 917 939 917 939 0.96

30 30 0.00023 0.062 16.2 2.0 1 23 945 967 945 967 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	30	0.00036	0.097	15.6	0.1	2	23	11	32	10	32	0.96
2	30	0.00022	0.06	16.2	4.3	1	23	38	60	38	60	0.97
3	30	0.001	0.28	14.1	0.3	1	23	66	88	66	88	0.98
4	30	1.6e-07	4.4e-05	26.1	1.2	1	23	94	116	94	116	0.98
5	30	3.9e-05	0.01	18.6	5.2	1	23	121	143	121	143	0.98
6	30	1.2e-05	0.0033	20.2	0.6	1	23	152	174	152	174	0.98
7	30	2.6e-06	0.00071	22.3	0.2	1	23	180	202	180	202	0.98
8	30	5.2e-06	0.0014	21.3	0.8	1	23	208	230	208	230	0.98
9	30	4.5e-07	0.00012	24.7	3.3	1	23	236	258	236	258	0.97
10	30	0.0002	0.054	16.4	1.2	1	21	264	284	264	286	0.95
11	30	6.3e-05	0.017	17.9	2.1	2	23	329	350	328	350	0.96
12	30	0.0053	1.5	11.9	6.9	1	23	356	378	356	378	0.98
13	30	0.37	1e+02	6.1	2.7	1	23	384	406	384	406	0.93
14	30	0.0018	0.48	13.4	1.9	1	23	413	435	413	435	0.97
15	30	5e-06	0.0014	21.4	0.7	1	23	441	463	441	463	0.98
16	30	4.2e-06	0.0011	21.6	1.4	1	23	468	490	468	490	0.98
17	30	0.018	4.9	10.2	1.9	1	20	497	516	497	518	0.92
18	30	2e-06	0.00053	22.7	0.3	1	23	525	547	525	547	0.98
19	30	3.6e-05	0.0097	18.7	1.3	1	23	553	575	553	575	0.98
20	30	9.1e-06	0.0025	20.6	0.4	1	21	581	601	581	602	0.95
21	30	0.011	2.9	10.9	0.4	2	23	694	715	693	715	0.96
22	30	0.029	7.7	9.6	3.3	1	23	720	742	720	742	0.97
23	30	0.03	8.1	9.5	0.5	1	23	748	770	748	770	0.98
24	30	0.00029	0.078	15.8	1.3	2	23	777	798	776	798	0.97
25	30	0.52	1.4e+02	5.6	0.6	1	23	804	827	804	827	0.94
26	30	4.9e-06	0.0013	21.4	1.7	1	23	834	856	834	856	0.96
27	30	0.00033	0.089	15.7	0.2	1	23	861	883	861	883	0.96
28	30	9.7e-05	0.026	17.3	1.6	1	23	889	911	889	911	0.96
29	30	1.4e-06	0.00039	23.1	0.8	1	23	917	939	917	939	0.96
30	30	0.00023	0.062	16.2	2.0	1	23	945	967	945	967	0.98

Sequence Information

Coding Sequence: ATGAAAACACACGTATCAAACAAAGCGCTGATTTGCAAAAGCTGCGATAAAGTGTTCACCGCCGTTAGTCTCTTGGTGAAGCACATGGCGAGTCACACGACAGATAGGCCCTTTCCTTGCGACCTCTGTCGGAAAACTTTCAAACGCAAACATGAACTCGTTAGCCACAAGAAGCAACACGAAGGCGTCAAAGATTTTGTTTGTGACATTTGCAGCTATGCGACAGGCCATAAAGCCTCGCTTGCCGTGCACATTAAGAGACACACGTGCGAAGCTCAATTCCCCTGCAACGTCTGCAACCGAAGTTTCTACACAAATTCACAACTTCAGAACCATATAAACACTCATTACGGAAAAAAGCATCAGTGCGAGTTTTGCGGCAAGTCGTTCATCCATAAGTACAACATGTTAATCCACCAGAAATCCCACGACCCGTCGAGAGACGTAAGGAAATTCCCGTGCGAGATTTGCGGCAAAACCTATCAGCGCAGAAACAAACTCATGATGCACATTCGTCTGCACATGGGAGAGATGCGCTACATATGTGACATATGTGGAAAAAGTGTGACGAGCAGTACGTCCTTGGAGACTCACCGAAGGGTCCACACCGGTGAGAAACCATTCATCTGCGACCTTTGCGGGAAAGCGTTCAACTCGAACAACTATCTGCGGGTCCACAAGCGTTCTCACACCGGAGAAAAACCTCACATGTGTAAACAGTGTGGGAAATCATTCACTCAGCGCTCCACGCTTGTTGTGCATATGAGGTACCATACTGGTCAGCGACCATACGAGTGTCTCATGTGTGACAAGAGATTTGTTACGAGGACCTTGTTGAATATTCATCAGAAATGTCATGAgtgtTCACCACAATACGGTGGTGAGTGGTGGAATGAAGGTTTGTGCACATCTCCCGAGTCTCCGAGAGCCATAAAGGGGGGGCCACCACTCATAGAAGGTCCGGGGAAAAAATCCGAAACCTTGGAATGTGACACGTGCGGCAAGAGGTGTAAGAGTAAAGCCAACCTTAATTTACACTCGAGAGTTCACGACCCTTCGAAACATCACAAGTGTAAAACTTGcgataaaatatttctggatAAGCACCATCTCGCAAGGCACACGGCCACCCACAGCAAGGAGAGGCCGTACGCATGCGACGTCTGCGACAAAACCTACAAGTGTCCTTTCAGGCTATCGAGTCATAAAAAAGGTCACTGCGAGAAGAAAAAACCCCACGTGTGCGATATCTGTGACTACTCGACAATCTACAGGTACTATCTGGAAATCCACAAAAAAAGGCATGCGTCTGATTTTACGTTCAAGTGTGATCTGTGCGGGAAAGGTTATTACACCGCTACAGATCTTAAAAGGCATCGAATGATCCATGACGGGAGTAAACACACATGTGACGTATGCGGTAAAGAGTTTACGATGGATAAAAACCTGAAAGACCATATGAGGATCCATAAATCCAACAGAAGGCGTTTCAACTGCGCACTTTGCggtaaaagctatttttatacTAGCCAATTAAATGTGCACAACTGCACCAAAGGAGAGGCTGTCAGATACGTCTGTGATGTTTGCGGAAAAACCTTGACGAGTGCGTCGTCCCTTCAGAGCCACCGCCGGCTACACACAGGGGAGAAACCGTTCATGTGTGACATCTGTCTCAAGTCCTTCAACACGGCCACTTACTTGCGCATACACAAGCGCTCACACACGGGAGAGAAGCCCCACGTGTGCGGCCAGTGCGGCAAGTCTTTCACCCAGCGCTCGACGCTTGTCGTTCACTACAGGTGGATGACAGGGAATTATGGTGACCTCACTGaacaattaagaaatatttcacCAGATGTATCATCAGATCACCAAAGTCTTCTGAGGCATTCCCGCAAATCGCTGGTAAAGGATCCTCAGGAGTTAACGGTTAGATGTAAAACAGCGGAACGTAAAGGCTCAAACTATTTTAAGGAtccaataataaatcaaaattcaGATCCTTCTAAAATGACCACACATAATCAGCCGAACAGTCTACATATGAAGAAACCTCATGGCACCAAAGGCCCGCTCATTTGCGACACATGCGGTAAGTTGTTCCCGTCCGTCAAGAGATTGAACATGCACAGGAAGATCCACACCGACATCCGTTACACTTGCGACATTTGCCTCAAGACTTATAAAAGTATCAGCATGTTTTATACCCACAAGAAATTCCACAAGAGTTTGAAAACGTACGATTGTGACGTGTGCGACTACCGTACTCCTTGGAAAGGGAATATGAACAATCATCGCAGGAGACATTTCGGTGAGACTAAAGTTACCTGTGACATGTGCGATAAAGGGTTCTACAACAAGTGTGATTTGGAAGAGCACAAAAATATCCACACAGGgaacaaaccttttaaatgcgACACATGCGAGTCGCCGTTTTGGTCCAAAAGGAGTCTGTGGGATCATAAAAAAGCGCAGCACAATTCAAACTTAAAAGAGTTCAAATGCACTCAATGCGGCAAAAGCTTTGTTTTCAAGAGCCGGCTAAACAGGCACTTGGAGGCCCACCGGGGGAAACGTTTCATGTGCGACATCTGCGGGAAATCCGTGACGTCGGACCAGTCTCTGAGGGCCCACAAAACCATCCACACGGACGAGAAGAAGTTCCTTTGTGACGTCTGCTCAAAGGCGTtcaacacaacacaatcctTAAAACTTCACAGGCGTACGCATACGGGCGAAAAGCCGTACCTGTGCAAGGAATGTGGCAAGGCGTTCACCCAGCGCTCGACGCTTGTTGTCCACACCCGTTACCACTCTGGGGAACGCCCATACATCTGTCACCTATGTTCCAAAGGTTTTGTTGCAAAGACCCACTTGAATGCTCACATTGAAAAACACAGCTGA
Protein Sequence: MKTHVSNKALICKSCDKVFTAVSLLVKHMASHTTDRPFPCDLCRKTFKRKHELVSHKKQHEGVKDFVCDICSYATGHKASLAVHIKRHTCEAQFPCNVCNRSFYTNSQLQNHINTHYGKKHQCEFCGKSFIHKYNMLIHQKSHDPSRDVRKFPCEICGKTYQRRNKLMMHIRLHMGEMRYICDICGKSVTSSTSLETHRRVHTGEKPFICDLCGKAFNSNNYLRVHKRSHTGEKPHMCKQCGKSFTQRSTLVVHMRYHTGQRPYECLMCDKRFVTRTLLNIHQKCHECSPQYGGEWWNEGLCTSPESPRAIKGGPPLIEGPGKKSETLECDTCGKRCKSKANLNLHSRVHDPSKHHKCKTCDKIFLDKHHLARHTATHSKERPYACDVCDKTYKCPFRLSSHKKGHCEKKKPHVCDICDYSTIYRYYLEIHKKRHASDFTFKCDLCGKGYYTATDLKRHRMIHDGSKHTCDVCGKEFTMDKNLKDHMRIHKSNRRRFNCALCGKSYFYTSQLNVHNCTKGEAVRYVCDVCGKTLTSASSLQSHRRLHTGEKPFMCDICLKSFNTATYLRIHKRSHTGEKPHVCGQCGKSFTQRSTLVVHYRWMTGNYGDLTEQLRNISPDVSSDHQSLLRHSRKSLVKDPQELTVRCKTAERKGSNYFKDPIINQNSDPSKMTTHNQPNSLHMKKPHGTKGPLICDTCGKLFPSVKRLNMHRKIHTDIRYTCDICLKTYKSISMFYTHKKFHKSLKTYDCDVCDYRTPWKGNMNNHRRRHFGETKVTCDMCDKGFYNKCDLEEHKNIHTGNKPFKCDTCESPFWSKRSLWDHKKAQHNSNLKEFKCTQCGKSFVFKSRLNRHLEAHRGKRFMCDICGKSVTSDQSLRAHKTIHTDEKKFLCDVCSKAFNTTQSLKLHRRTHTGEKPYLCKECGKAFTQRSTLVVHTRYHSGERPYICHLCSKGFVAKTHLNAHIEKHS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448778;
90% Identity: iTF_01448778;
80% Identity: -