Basic Information

Insect: Timema shepardi
Gene Symbol: BAZ2B
Assembly: GCA_902151425.1
Location: CABFVX010000997.1:1-65594[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 5.4e-22 7.9e-18 66.3 0.0 5 76 705 776 703 777 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	5.4e-22	7.9e-18	66.3	0.0	5	76	705	776	703	777	0.90

Sequence Information

Coding Sequence: NCTTATTGGCCAAGGGGTGACTCTGCCTCGAGTGCTGGGAGTAGTGGTGTTCACTCATTGTTCAGTGGAATCCCCGGTGGGTTTGCTAACCACCTTGGGGGCCACCCCTTACCTGGAGCCTTTGCGATGATGAGTGGCAGAGGAGGACCTGGGGGTGGCTATCACCACCCACCCACTACTGCCTCAGGGACATACGGGGGACTAGGCACACTCAGCGTAGCAGCCAGCCAGGCTGCTAGTCTCGGTATCAACCCCACCAGTGCAGCTTGGTGGACAATGGCCTCTCATCTCGCTGCTCAAGACTACCTAGTGAGACTCCAGGCCAGTGGCATGTCGTTCGGGGGCCTCACAGGGGCGGAGTCACTGCTTCCAGGGTATCCTATGCTGGGAGGCCCTCACTCACAACCTCATGCTTCCTCAAGCAAGTCGTCTGGTGGCGGGAAGTCAAGCTCCAAGGCTACCACCACAACAGTTTCCTCATCTATGCCCTCTTCAACAAGTCTGACGAGTAGCAGCTCGCATCGTGAACGAGAGAGGGAGCGAGAGCGAGAAAGGGACAGAGACCGAGAGCGAGACAGGGATAGAGACAGAGAGCGAGAACGAGATAGAGCAGAGAGGGAACGTGAGCGTGAGCGAGATAGGATGGAGAGAGACAGAGAAACGCCCATCCCTGCCACTGCTGGGGCACTCTCACTCCATGCCCCGCCTGGCATCATTAGTGATCCCACCAGCATCTTGGGTGGAGTGCGTCTTCCTCCAGATACAGAGATCATCAAGTACACCTCATCAATTGTAGGACCCAAGATCCCGGGCACCACTAATAGGGGTCGCAAGAAAACCATCTCCTTGGACCCTCCTTCTGTGAGTGTCATGCCCACACACTCCTCCACGGGGCTACTTATAGAAAGAGGTGGCCGCAAGCATTCACGCAGTAGACTAGGGGACCCCATGGATTATCGTGAAACATCTATAGGCGTTTCTTCACTTGATCGAGACCGTGTGGAGGTGATCAAACTCCCTTCTCTTGGTAGCAATGGGGCTATCCCACTCAACATCCCATCGTTTGGGGCAGGGGGCAACCTTTCCGCGTCTACACCAGATAGTGATGCCCCTCTCAACCTTTCTCTGAAACCTCAAGCCAGCGCCAGCAACTTGGCCGAGACGCCAAACAGTAGCATAACCAGCAACAGTAGTGGCACACCTCACATCTCGTCTCTCTCCTCACTTTCTAACATGTCAGCATCGCTCAACACCTCTACACCCACCATACCGGACAGAATATCTCGCCGAAAGCCTGGCCCAAAGCCCCGAAGGGTTATCCAAACATCAACTCCAACATCTATACCCCCGTCTCCCAGCCCATCACTAGCTCAGTTGTTTGCTGCTGCAGACTCTCCCCGGCCATCTAGTGGCAGTGAAGAGAACGATTCTTCTTCGCACAAGGATGGTCGGCCTCGTAACCTTGGCCGAGGCACGTCCAAGCCAAAAAAGAACACAGTAGCTTCTCTGCTGGCGCAGAGCCGTGCACTGGGGATCAAGCCGACACCTGGGCTTGAAGTCTCTCCTTTAAACCACCAGGTGTCTCTGCTGAAGTCCAGCATTCTGTTGGCACAACAACAACAGCAGCAACATTCTTCAGAACAACAACAGGAAATGGACCAGTTGGAACAGTCTCAACCTGAGCAACAAGACAATGACCAACAGCAGGAACAGGAACAGCAACAGCAACAGCAGCAGCATGAACAACAGCCACCAAACAAGGATCAAGATCCTGGCGACAGTGAGGATGGTCGTGTGAGTACTAGTGAGGACGGAGACAGGCGATCTCACAACAACACGCCAGACTCAGCTGACAAGAAGAGGCACCTGGTTGGTATTAGCTCACGGTCCGATGACAACAAGCTGAAGATACGTTCGGTGGAAGGTCTGAGTGAGGACAGCAGTGTGGCAGACGTCAGCACCGACTCTGGGTCAGCATCAGAAGGGGAAGGGGGTCTGCCCAGTGACAGCGAGGAAGGAGACGAGGGACAGCTTTCAGAGTGTGGCACCAAAAGAGAGGGGGACGATGATTCAGGACCCGCAAACAAGAAGCGAAAACTTGAGATTGATGTCCGTGAGATCCGCATCCCCCTGGAACACGGGTGGCGAAGAGAGACCCTAATCAGTGGAGTGAGCAGGATGGGAACCATCAAAGGAGAGGTCAGCTATTTCACTCCCTGCGGTCGCCGCTTCAGGCAGTATCCAGATGTTTTAAGGTTTTTGGAAAAGAACAACATCAGCGACTTGACTAGAGAGAACTTCAGCTTTAGCCCCAAAATCCTTGTAGGAGACTTCCTCCAGCCAACTGGTGGTGATGAGCCTGTCAGGTTGTCAGAGGAACAGGTGGTACGTAGGCTCGAAGAACTGCGTGCTACCAAGAATTATCGACCGCATACCTCTAATGCACACAGAATGGAAGCGGCCAGACTCGCCCAGGAGCAAAAGATTCAACAACAGCTGGAGAAGGAGAAAGCAGCCATGATGGCCAAGGAGGCTAAGAGAGTGGCCAAGGAAGAGGCAGCAAGGCAAAAAGAACATGTCAGGCTACTGAAAGAACAGGAGCGCTGCGAGAGGCAGGAGGCCATCAGGAAAGAGAGGGAACTACGCAATCAGCAGCTTATGGAGGGGAGGAAGAGACTCGCTTTCACGCTTGAACAAAAAATGCACATCATTCGTGAAATCGAGAAGGGCAAAAGCAAATCAGATGTTAGCAGAGAGTTAGGACTAGCCAGTTCGACCGTTGCAACCATTTGGAAAAATCGGGAGAGTGTCTACTCTGCCTATGAAAACAACATACCGAAGAGCGAAACTCCTCCATCCCAACAAAATAACGTAAACGATGATGAGCCCGTGTTGTCCCAAACTGAGACGGCCCGGCGCCGACGCCAGGAGGAGCTGGATAAGCAGCGCCAAGAGGAGCAGCTTCGCAAGCAGCAGGTAACAAACCACCCGCATGTAGTGTTATAA
Protein Sequence: XYWPRGDSASSAGSSGVHSLFSGIPGGFANHLGGHPLPGAFAMMSGRGGPGGGYHHPPTTASGTYGGLGTLSVAASQAASLGINPTSAAWWTMASHLAAQDYLVRLQASGMSFGGLTGAESLLPGYPMLGGPHSQPHASSSKSSGGGKSSSKATTTTVSSSMPSSTSLTSSSSHRERERERERERDRDRERDRDRDRERERDRAERERERERDRMERDRETPIPATAGALSLHAPPGIISDPTSILGGVRLPPDTEIIKYTSSIVGPKIPGTTNRGRKKTISLDPPSVSVMPTHSSTGLLIERGGRKHSRSRLGDPMDYRETSIGVSSLDRDRVEVIKLPSLGSNGAIPLNIPSFGAGGNLSASTPDSDAPLNLSLKPQASASNLAETPNSSITSNSSGTPHISSLSSLSNMSASLNTSTPTIPDRISRRKPGPKPRRVIQTSTPTSIPPSPSPSLAQLFAAADSPRPSSGSEENDSSSHKDGRPRNLGRGTSKPKKNTVASLLAQSRALGIKPTPGLEVSPLNHQVSLLKSSILLAQQQQQQHSSEQQQEMDQLEQSQPEQQDNDQQQEQEQQQQQQQHEQQPPNKDQDPGDSEDGRVSTSEDGDRRSHNNTPDSADKKRHLVGISSRSDDNKLKIRSVEGLSEDSSVADVSTDSGSASEGEGGLPSDSEEGDEGQLSECGTKREGDDDSGPANKKRKLEIDVREIRIPLEHGWRRETLISGVSRMGTIKGEVSYFTPCGRRFRQYPDVLRFLEKNNISDLTRENFSFSPKILVGDFLQPTGGDEPVRLSEEQVVRRLEELRATKNYRPHTSNAHRMEAARLAQEQKIQQQLEKEKAAMMAKEAKRVAKEEAARQKEHVRLLKEQERCERQEAIRKERELRNQQLMEGRKRLAFTLEQKMHIIREIEKGKSKSDVSRELGLASSTVATIWKNRESVYSAYENNIPKSETPPSQQNNVNDDEPVLSQTETARRRRQEELDKQRQEEQLRKQQVTNHPHVVL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448573;
90% Identity: iTF_01448573; iTF_01447583;
80% Identity: -