Basic Information

Insect: Timema podura
Gene Symbol: Hr39
Assembly: GCA_033556935.1
Location: JAVRXN010000002.1:28152419-28178459[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.21 2.3e+03 -0.5 5.2 71 164 195 283 142 354 0.64

2 3 1.6e-08 0.00017 23.0 0.0 1 43 527 571 527 578 0.76

3 3 1.5e-70 1.7e-66 227.2 1.6 164 408 589 840 575 840 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.21	2.3e+03	-0.5	5.2	71	164	195	283	142	354	0.64
2	3	1.6e-08	0.00017	23.0	0.0	1	43	527	571	527	578	0.76
3	3	1.5e-70	1.7e-66	227.2	1.6	164	408	589	840	575	840	0.86

Sequence Information

Coding Sequence: ATGGAGACTTGGACTGCCGCCGTTGCACATTCCCCGCCCGCCCCCGGCAAGGCGCCGCGCCCCCCGGACACTGGAGGCGGCACCAAGGAGGTCACCTCCGGCTCCGTCACCGTTATCAGCGTGCACGATTCGGAGCTAGGAACCGTGATACCGGACAGTCCGAGATCTACGGATAAGTCTGACCTGTCTGTCATTCGCCCGAGGATGATGGGCAGCTTGACCATGACACCCATCGAGAGAGACAACGAAGATGAAGGCTCAGGCTCTGATGGAGAAGTCAGTAAAATAGACTTCACTGGAGTGAACTTGAGGACTAAAAAGAAACGAGGTACTGAAGGGGACTCTCGGGATGGCTTTGAGGAGCCAGAGAGACCTATGTCTTGGGAGGGTGAACTCTCCGATACCGAGATGAGCATTGCCACTACCGGCAAACAGGACCTTGAAGAGACTTCCATGGAAGGTGTGCAGGTGTGTGGTGTGAACAACAACCACTTGCGGCTGGATGAAGACAAAGCCCATGCCTCACCACTTAGGTTCACAGACTCGGGAATTGTTTTAAACCTCCAGGTGGACCACATTCAAGCAAAGCCCTCAACCCACCAAGTGTCCACCTCCAATAATGGAGGGGTACCTCCACCAACGTCATCGGCGAGTGAACTACCCCTGTTGGTGGATAAGCTGCTGGGCGGCACCGGCAGTTACAATACCCCCTCGCACAGCCCCGTACTCCAACACAGGCACCACCACCCGTTGAAACATGCCGTACCACCGACGCCCAGCCCCGACTCTGCCATTCACTCGGCCTACTCGTATGGCTCACCTGCGCAGAGTCCTGTCACCTCCCGACATGGTAGCAGCCATGGCCTTCCATCGTCAGGATTTAGTTCCCCGTACACTCCTTCGCTGTCGCGCAACAACTCTGATGCTTCCCAGTACGGGGGCTCCCAGCACAGCAGTTGCTATAGCTACTCGTCTGTATCCGTCTCACCAACGCAGTTCTCACCCACGCACTCACCCATCCAGTCCCGGCACATGCACGCGGGCTTCCCCTCGCCTGTGATGCCCCCACGGGGGACCGGTTCTCCTCTACATGCGGGTGTTGTGTATGGGGGATGGGTGTTCACAGGAACCTGTCCGGACTCACAGGCCCTGGGGAGGAGGGAGTCCAGGAGGGAACGACCCCAGACCTCTCGGTCCCACGACTATTCCGAGAATTCGCATGCGAAGAATGCCAGAGGCATGTTAGATGATCGGGAAGGAGGTAGCAGTATTCTAGATGACAAAATGTCTTCCTTGGCAGCTGACTTGGTTCAGCATTCTGCTTTGGCAGCTCCACCCGGTATTTCGCGGCAGCAGCTCATTAATAGCCCTTGTCCTATTTGCGGTGATAAAATCTCTGGTTTCCATTATGGCATCTTTTCATGCGAAAGCTGCAAAGGTTTCTTCAAGAGGACTGTTCAGAATCGCAAGAACTATGTCTGTTTGCGAGGTTCTTTGTGTTCTGTTACAATATCTACCAGGAAAAAGTGCCCTGCATGTCGCTTCGAGAAGTGTCTCAAAATGGGCATGAAACTTGAAGCAATTCGCGAAGACCGCACGCGCGGAGGCCGCAGCACTTATCAGTGCTCTTACACGCTGCCGGCCAGTCTCGTTGCTCCCTCTGGAAGTGACAAGATGTTTGCCCCCTCTGGTGACCCCCAGGTCAAGCTGGAGGCTCCAGATTTGGGGGCGATGGCTGGGAGCAGCTCCCACCTAAACAGCAGGCATCATGAGAAACTTGTCCCTCAATTATTGCAAGAAATAATGGATGTGGAACATTTGTGGCACTACAATGGACAGGAGGCTCATAAGATGTCTGCCAAtaacagtagtagtagtagcagcagcaaTAACAGTGTAAACAATAGCAATAGCAGTAGTTCAAGCAATAACCAAGATTTTGTGTCCATGTGCAATATCGCAGACCATCGGCTCTATCGACTGGTCAAGTGGTGTAAGAGTCTTccgcttttcaaaaatatttcgATTGACGACCAAATATCATTGCTGATCAACGCTTGGTGCGAGCTGCTGCTGTTCTCGTGTTGTTTCCGCTCAATGTCAACACCCGGGGAGATCCGTGTGAGTCTCGGCAAGTCCATAACCTTGGCACAGGCGCGAGAACTGGGGCTTGGCGCCTGCATCGAGAGGATGTTAAACTTCACTGAACACCTTCGCAGACTCAAGGTGGACAAATACGAGTATGTCGCCATGAAGGTCATCGTTTTGCTCACCTCAGATGCCAGTGACttgagggaaagtgaaaaagtAAGAGCGTCCCAAGAGAAGGCTTTGGAAGCATTGCAGCAGTACACGCTTACTCACTATCCGGACATTCCTTCCAAGTTCGGAGAACTACTGCTCAGGATCCCGGAACTACAGAGAACGTGTCAGgttggcAAGGATATGCTGtctgtaaaaaataaagaaggggAAGGCCCAAGTTTCAACTTATTGATGGAGTTACTGAGAGGAGATCATTAA
Protein Sequence: METWTAAVAHSPPAPGKAPRPPDTGGGTKEVTSGSVTVISVHDSELGTVIPDSPRSTDKSDLSVIRPRMMGSLTMTPIERDNEDEGSGSDGEVSKIDFTGVNLRTKKKRGTEGDSRDGFEEPERPMSWEGELSDTEMSIATTGKQDLEETSMEGVQVCGVNNNHLRLDEDKAHASPLRFTDSGIVLNLQVDHIQAKPSTHQVSTSNNGGVPPPTSSASELPLLVDKLLGGTGSYNTPSHSPVLQHRHHHPLKHAVPPTPSPDSAIHSAYSYGSPAQSPVTSRHGSSHGLPSSGFSSPYTPSLSRNNSDASQYGGSQHSSCYSYSSVSVSPTQFSPTHSPIQSRHMHAGFPSPVMPPRGTGSPLHAGVVYGGWVFTGTCPDSQALGRRESRRERPQTSRSHDYSENSHAKNARGMLDDREGGSSILDDKMSSLAADLVQHSALAAPPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSLCSVTISTRKKCPACRFEKCLKMGMKLEAIREDRTRGGRSTYQCSYTLPASLVAPSGSDKMFAPSGDPQVKLEAPDLGAMAGSSSHLNSRHHEKLVPQLLQEIMDVEHLWHYNGQEAHKMSANNSSSSSSSNNSVNNSNSSSSSNNQDFVSMCNIADHRLYRLVKWCKSLPLFKNISIDDQISLLINAWCELLLFSCCFRSMSTPGEIRVSLGKSITLAQARELGLGACIERMLNFTEHLRRLKVDKYEYVAMKVIVLLTSDASDLRESEKVRASQEKALEALQQYTLTHYPDIPSKFGELLLRIPELQRTCQVGKDMLSVKNKEGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448615;
90% Identity: iTF_01448615;
80% Identity: iTF_01449686;