Basic Information

Insect: Timema monikensis
Gene Symbol: -
Assembly: GCA_902151445.1
Location: CABFVZ010005088.1:3627-11250[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.8 3.7e+02 4.0 0.1 1 13 83 95 83 97 0.86

2 15 5.4e-05 0.011 18.2 0.4 3 23 122 142 120 142 0.96

3 15 0.00015 0.031 16.8 2.4 2 23 150 171 150 171 0.96

4 15 4.6e-07 9.5e-05 24.7 3.2 1 23 177 199 177 199 0.95

5 15 7.3e-07 0.00015 24.1 0.9 1 23 205 227 205 227 0.98

6 15 2.7e-05 0.0056 19.1 0.2 1 23 233 255 233 255 0.99

7 15 5.2e-05 0.011 18.3 1.0 1 23 261 283 261 283 0.96

8 15 0.00053 0.11 15.1 0.1 1 23 289 311 289 311 0.97

9 15 0.0037 0.77 12.4 0.7 1 21 317 337 317 338 0.94

10 15 9.7e-07 0.0002 23.7 1.3 1 23 345 367 345 367 0.99

11 15 1.1e-05 0.0023 20.4 0.9 1 23 373 395 373 395 0.98

12 15 1.6e-05 0.0034 19.8 0.3 1 23 401 423 401 423 0.96

13 15 1.2e-05 0.0025 20.2 1.1 1 23 429 451 429 451 0.96

14 15 3.1e-06 0.00063 22.1 1.2 1 23 457 479 457 479 0.98

15 15 5.6e-08 1.2e-05 27.6 0.1 1 23 485 507 485 507 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.8	3.7e+02	4.0	0.1	1	13	83	95	83	97	0.86
2	15	5.4e-05	0.011	18.2	0.4	3	23	122	142	120	142	0.96
3	15	0.00015	0.031	16.8	2.4	2	23	150	171	150	171	0.96
4	15	4.6e-07	9.5e-05	24.7	3.2	1	23	177	199	177	199	0.95
5	15	7.3e-07	0.00015	24.1	0.9	1	23	205	227	205	227	0.98
6	15	2.7e-05	0.0056	19.1	0.2	1	23	233	255	233	255	0.99
7	15	5.2e-05	0.011	18.3	1.0	1	23	261	283	261	283	0.96
8	15	0.00053	0.11	15.1	0.1	1	23	289	311	289	311	0.97
9	15	0.0037	0.77	12.4	0.7	1	21	317	337	317	338	0.94
10	15	9.7e-07	0.0002	23.7	1.3	1	23	345	367	345	367	0.99
11	15	1.1e-05	0.0023	20.4	0.9	1	23	373	395	373	395	0.98
12	15	1.6e-05	0.0034	19.8	0.3	1	23	401	423	401	423	0.96
13	15	1.2e-05	0.0025	20.2	1.1	1	23	429	451	429	451	0.96
14	15	3.1e-06	0.00063	22.1	1.2	1	23	457	479	457	479	0.98
15	15	5.6e-08	1.2e-05	27.6	0.1	1	23	485	507	485	507	0.98

Sequence Information

Coding Sequence: ATGGATGAATCACATATAGTCGAGAATTCAGTGGAACCTATCGTCTCTATTACTGTCAAAGATGAAATCAAGtgTGAAGAGGGAGGAGATCTGTCATCCCTCATACATTCAACAGTCGGCGACACTGATGACTGGGGGGCGTTTGTTCAGAAGAATCAAGTTGACTCTCAAGATAATAATGGTGCCAAGTGGTTAGGCGAAGTGGTGAAGAAGGTCCAACTGTGGCCCATCAACAAGACCCCAAGACATTCATGCCAAGTGTGCGGCAGGTTCCTGAAGCAATCCGCAGGGGACGCCATCACATGTCGGAGTTGTGCGGGACTCGTCCCACGGCTCAAGGCGAGGACGGCCGGACTGCTCTTCTGTGACCACTGCGGCCGGGGATTCACGGGGAAGGGTCAGCTTGCAATGCATATCAAGGCCCATTCCTCCCGACCTCCTGTGCCCGTGTGCTTGGTTTGTGATAAGACGTACGCCAACTTTACTCAGTTGAAACGCCACCATCGTCTGCACACAGGTGACAGAAGGTTTCTATGTGATATGTGTGGGAAGGCATTCAAGCAAAGCGACCATCTTAAGAGGCATCGGATGAGACACCTAGGAGAGAAACCTCACCAATGTCCCATCTGTGGCCGTGGGTTTGTGGCTCGTGATCACTTGGTTACACACATCCGAACACACAGCGGCGAGCGCCCGTATTCCTGCTCTGAGTGCAACATGCGCTTCCCCACTCGTGGAGGGGTGGTCATACACATGCGGACACATACAGgtgaGAGACCCCACTTTTGTGTGATTTGCGGGAGAAGCTTTGCGTCAATGGCTGGATTAAGGTCTCATCGACGCTCTCACGCAGGCAATAGGACCTTCGACTGCGAAGAGTGCAAAGCAGAGTTCCCTCTGCAGAAGGACCTTAAGATCCATATCATGTCACATCTCGGGATCAACCCTTTCACCTGCGAGACCTGCTCTAAGGTCTTCATAGACTTCACCAAGTTCACGCTCCATCTAGAGACTGGCGAATGTGAGAACGGCTACACATGCGCCCACTGCAACTTGACGTTCATTGACCGCTCGGCACTGGCAAAACATATCAGGAAACATATAGCGGAGAAACCATATGTCTGTGATCTATGCAACAAAGCGTACACGTTCAGGTACCAGTTACGGACACACATCATGGAGCACACTGGTGAAAGGCCGTATGCTTGTCTTGTGTGTGGTAAGACATTTACCGCACAGAGCTCGCTCAAGTCACATTTTATAGTCCATTCAGGTGTGAAGGCTCACGCGTGTGATGTGTGCGGTTTTGCTTTTGCTCGTGCTGCTCACCTTCGCACTCACAAGCGCATCCACACtggtgaaaaaccatttagttgtAACCGCTGTGAAGCAAGCTATAAGAACAGTAGTAGTCTTAAGATCCACATACGAACACACACTGGGGAGAAACCATTCATATGTCCTGAGTGCGGGCGTGCCTTTGCCGTTAGCACCAATCTGAAGGCACATATCAGGACTCACGGGAGCCGGTCTTAA
Protein Sequence: MDESHIVENSVEPIVSITVKDEIKCEEGGDLSSLIHSTVGDTDDWGAFVQKNQVDSQDNNGAKWLGEVVKKVQLWPINKTPRHSCQVCGRFLKQSAGDAITCRSCAGLVPRLKARTAGLLFCDHCGRGFTGKGQLAMHIKAHSSRPPVPVCLVCDKTYANFTQLKRHHRLHTGDRRFLCDMCGKAFKQSDHLKRHRMRHLGEKPHQCPICGRGFVARDHLVTHIRTHSGERPYSCSECNMRFPTRGGVVIHMRTHTGERPHFCVICGRSFASMAGLRSHRRSHAGNRTFDCEECKAEFPLQKDLKIHIMSHLGINPFTCETCSKVFIDFTKFTLHLETGECENGYTCAHCNLTFIDRSALAKHIRKHIAEKPYVCDLCNKAYTFRYQLRTHIMEHTGERPYACLVCGKTFTAQSSLKSHFIVHSGVKAHACDVCGFAFARAAHLRTHKRIHTGEKPFSCNRCEASYKNSSSLKIHIRTHTGEKPFICPECGRAFAVSTNLKAHIRTHGSRS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01447751; iTF_01450794; iTF_01445846; iTF_01449818; iTF_01446811; iTF_01444993;
90% Identity: iTF_01449818;
80% Identity: iTF_01445846;