Basic Information

Insect: Timema douglasi
Gene Symbol: -
Assembly: GCA_901482245.1
Location: CABEEJ010000358.1:283094-291313[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.7 4.1e+02 4.0 0.1 1 13 67 79 67 81 0.86

2 15 5.2e-05 0.012 18.2 0.4 3 23 106 126 104 126 0.96

3 15 0.00011 0.027 17.2 2.0 2 23 134 155 134 155 0.96

4 15 4.4e-07 0.0001 24.8 3.2 1 23 161 183 161 183 0.95

5 15 6.9e-07 0.00017 24.1 0.9 1 23 189 211 189 211 0.98

6 15 2.6e-05 0.0062 19.2 0.2 1 23 217 239 217 239 0.99

7 15 4.9e-05 0.012 18.3 1.0 1 23 245 267 245 267 0.96

8 15 0.0004 0.094 15.5 0.1 1 23 273 295 273 295 0.98

9 15 0.0036 0.85 12.5 0.7 1 21 301 321 301 322 0.94

10 15 9.2e-07 0.00022 23.7 1.3 1 23 329 351 329 351 0.99

11 15 1.1e-05 0.0025 20.4 0.9 1 23 357 379 357 379 0.98

12 15 1.7e-05 0.0039 19.8 0.3 1 23 385 407 385 407 0.96

13 15 1.2e-05 0.0028 20.3 1.1 1 23 413 435 413 435 0.96

14 15 2.9e-06 0.0007 22.2 1.2 1 23 441 463 441 463 0.98

15 15 5.4e-08 1.3e-05 27.6 0.1 1 23 469 491 469 491 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.7	4.1e+02	4.0	0.1	1	13	67	79	67	81	0.86
2	15	5.2e-05	0.012	18.2	0.4	3	23	106	126	104	126	0.96
3	15	0.00011	0.027	17.2	2.0	2	23	134	155	134	155	0.96
4	15	4.4e-07	0.0001	24.8	3.2	1	23	161	183	161	183	0.95
5	15	6.9e-07	0.00017	24.1	0.9	1	23	189	211	189	211	0.98
6	15	2.6e-05	0.0062	19.2	0.2	1	23	217	239	217	239	0.99
7	15	4.9e-05	0.012	18.3	1.0	1	23	245	267	245	267	0.96
8	15	0.0004	0.094	15.5	0.1	1	23	273	295	273	295	0.98
9	15	0.0036	0.85	12.5	0.7	1	21	301	321	301	322	0.94
10	15	9.2e-07	0.00022	23.7	1.3	1	23	329	351	329	351	0.99
11	15	1.1e-05	0.0025	20.4	0.9	1	23	357	379	357	379	0.98
12	15	1.7e-05	0.0039	19.8	0.3	1	23	385	407	385	407	0.96
13	15	1.2e-05	0.0028	20.3	1.1	1	23	413	435	413	435	0.96
14	15	2.9e-06	0.0007	22.2	1.2	1	23	441	463	441	463	0.98
15	15	5.4e-08	1.3e-05	27.6	0.1	1	23	469	491	469	491	0.98

Sequence Information

Coding Sequence: ATGCTGAGAAGAAAGTCACAGGAAAAGtgTGAAGAGGGAGATCTGTCATCCCTCATACATTCAACAGTCGGCGACACTGATGGTTGGGGGGCGTTTGTCCAGAAGAATCAAGTTGACTCTCAAGATAGTAATGGTGCCAAGTGGTTAGGCGAAGTGGTGAAGAAGGTCCAACTGTGGCCCATCAACAAGACCCCAAGACATTCATGCCAAGTGTGCGGCAGGTTCCTGAAGCAATCTGCAGGGGACGCCATCACATGTCGGAGCTGTGCGGGACTCGTCCCACGGCTCAAGGCGAGGACGACCGGACTGCTCTTCTGTGACCACTGCGGCCGAGGATTCACGGGGAAGGGTCAGCTTGCAATGCATATCAAGGCCCACTCCTCCCGACCTCCTGTGCCCGTGTGCGTGGTTTGTGATAAGACGTATGCCAACTTTACTCAGCTGAAACGCCACCATCGTCTGCACACAGGTGACAGAAGGTTTCTATGTGATATGTGTGGGAAGGCCTTCAAGCAAAGCGACCATCTTAAGAGGCACCGTATGAGACACCTAGGAGAGAAGCCTCACCAATGTCCCATCTGTGGTCGTGGGTTTGTGGCTCGTGACCACTTGGTTACACACATCCGAACACACAGCGGCGAGCGCCCGTATTCCTGCTCTGAGTGCAACATGCGCTTCCCCACTCGTGGAGGGGTGGTCATACACATGCGGACACATACAGgtGAGAGACCCCACTTTTGTGTGATCTGCGGGAGAAGCTTTGCATCAATGGCTGGATTAAGGTCTCATCGGCGCTCTCACGCAGGCAATAGGACCTTCAACTGCGAAGAGTGCAAGGCGGAGTTCCCTCTGCAGAAGGACCTTAAGATCCATATCATGTCACATCTCGGGATCAACCCTTTCACCTGCGAGACCTGCTCTAAGGTCTTCATAGACTTCACCAAGTTCACGCTCCATCTAGAGACTGGCGAATGTGAGAATGGCTACACATGCGCCCATTGCAACTTGACGTTCATTGACCGCTCGGCACTGGCTAAACATATCAGGAAACATATAGCAGATAAACCATATGTCTGTGATCTGTGCAACAAGGCATACACGTTCAGGTACCAGTTACGGACACACATCATGGAGCACACTGGTGAAAGGCCATATGCTTGTCTTGTGTGTGGTAAGACATTTACCGCACAGAGTTCGCTCAAGTCACATTTTATAATCCATTCAGGTGTAAAGGCTCACGCGTGTGATGTGTGCGGTTTTGCTTTTGCTCGTGCTGCTCACCTTCGTACTCACAAGCGCATCCACACTGGTGAAAAACCTTTTAGTTGTAACCGCTGTGAAGCAAGCTATAAGAACAGTAGTAGTCTTAAGATCCACATACGAACACACACTGGGGAGAAACCATTCATATGTCCTGAGTGCGGGCGTGCCTTTGCCGTTAGCACCAATCTGAAGGCACATATCAGGACTCACGGGAGCCGGTCTTAA
Protein Sequence: MLRRKSQEKCEEGDLSSLIHSTVGDTDGWGAFVQKNQVDSQDSNGAKWLGEVVKKVQLWPINKTPRHSCQVCGRFLKQSAGDAITCRSCAGLVPRLKARTTGLLFCDHCGRGFTGKGQLAMHIKAHSSRPPVPVCVVCDKTYANFTQLKRHHRLHTGDRRFLCDMCGKAFKQSDHLKRHRMRHLGEKPHQCPICGRGFVARDHLVTHIRTHSGERPYSCSECNMRFPTRGGVVIHMRTHTGERPHFCVICGRSFASMAGLRSHRRSHAGNRTFNCEECKAEFPLQKDLKIHIMSHLGINPFTCETCSKVFIDFTKFTLHLETGECENGYTCAHCNLTFIDRSALAKHIRKHIADKPYVCDLCNKAYTFRYQLRTHIMEHTGERPYACLVCGKTFTAQSSLKSHFIIHSGVKAHACDVCGFAFARAAHLRTHKRIHTGEKPFSCNRCEASYKNSSSLKIHIRTHTGEKPFICPECGRAFAVSTNLKAHIRTHGSRS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448785;
90% Identity: iTF_01449818;
80% Identity: -