Tgen002616.2
Basic Information
- Insect
- Timema genevievae
- Gene Symbol
- prdm10_2
- Assembly
- GCA_902155825.1
- Location
- CABFWO010000089.1:82346-124635[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0017 0.33 13.5 0.5 2 23 730 751 729 751 0.96 2 11 9.4 1.8e+03 1.7 0.1 14 23 760 769 755 769 0.91 3 11 0.0014 0.26 13.8 3.1 1 23 775 798 775 798 0.97 4 11 0.00029 0.054 15.9 1.9 2 23 848 869 847 869 0.97 5 11 0.00097 0.18 14.3 0.1 1 23 905 927 905 927 0.98 6 11 0.0046 0.86 12.1 1.2 1 23 933 956 933 956 0.95 7 11 0.0085 1.6 11.3 5.7 1 23 961 983 961 983 0.98 8 11 3.8e-05 0.007 18.7 3.7 1 23 989 1012 989 1012 0.94 9 11 0.007 1.3 11.6 1.4 1 23 1047 1070 1047 1070 0.95 10 11 0.00048 0.091 15.2 2.5 1 23 1092 1115 1092 1115 0.96 11 11 0.00091 0.17 14.3 1.8 3 23 1155 1176 1154 1176 0.98
Sequence Information
- Coding Sequence
- ATGGACACCAGCAGTAGTCCCCAGAAGGTACCTGGGGATGAAGACGATCTCGCTGGGGTCATTATACCGAACCAGACCGAGGTAGATCTGAACGATTGGATCCCTGTTGTCAATTCACATCTCGATGCCGACGGAAAAGAGGTGGCGGGGACATCGCGTTTGCTGTTTCTTACGGTGGAGTATGTCGAAGAACCCACCGGAGATTACGGCAACTCTGGCTTCTCTTCGTTTGAGCCAGTCGCATCTTTCTCTCCCCACATCTCATCTTCCTTGTCAGAGTTTGAACAGCGCGTTAGCCCCCTGGACCCAAACATGAGCTCGGCGGCTTGCTACTCCCCAGTGTACACCATCGACCAGAGCCCCACCACTGCGGATGTGAACCAATCATCCAACCCCAGCTCGCCCTTTCAAAACCAAATGGTGGTTCTTCCTAATCCAACCAGTCCCTTAATCTCCTCGTCCACACCTTCAAGTGCCCTCTCTCCATCCGGCCAAACATTTGTCGACACCTCACACTCGACTGTCTCGTTGACAGGCGGCAGAATCATCCATACATATGTCACACACCTTTCCAGTCCTGATTCCACCCTCCCAATCCTGTCGCAGTCCGAGACAGAGGATGGCAAGGGTCTTCTCCAAGAAGTTGAAATGGGAGGGACATTTTATCATGAGAGCCCCACAGGGGGCTCCCCTCACTCTTCTGGCTCGGAGAACTATGTCGTGTCTTCGTCTGGAACTCTGTTGAATGCAATTCCCTCTTCGGCGGCAGACTTCGTGGAAGCTATCTCCATAAATGTGGACGCGTCTCCCCCGGGTGTGGTGGACTCTACCAGCGACTTATTGATGCACAGTTCACAACTTGTTCCGGGAGCAGAGTTCTCCGAGCTGACGGCCGGTGGTACGATGGTCCTGACGAGCCCCAACCAGAAGAGGGATCCAGGTGCCTTGGAGCATTTCCAGGTGGTCATCTCGAGCAGTGACGGAGAGAACATCGCGTACAGTATCGACGGACAGACCACCTACATCAACTCTGCCCAGATCAGAGCGGACTTGCTGAACGCAGCTAGGGCCGGAGCCACCACCTTTGAGGACTTGGAAGCTGTCATCAATCTGTTCAAGTCTCATGGTGTTATAATTGAAGGTGTGGATGAGAGCGAGCTGAGAGGGGAACAGCTTCAAGAGAGTCTCAACATAAACGAAGTGAATCTGGAGTTAACTTCGGAGCCGCCAGAGTTCATCAACTCGACCTTACTCGGGTCTAGCGTCGACTTGGCTATGCGGCGGGAAGTTCATCTGGACCCTGAGATATTAAAGGAAGGTGTAATGGCCAGCCACTCCTTGGAACTCACTAAGGAGTCATTTTGCGAGGACCTACTGATGGAAGGGACATCTTGCGATACGAAACCTATAGACTTGCAAGAAGACAGCAAGGACCTACCGATGGAACAGGCACCTTGCGACGCTATAACGATACACTCGCAAGAAGACAACAAGAACCTCATGGTGGAACAAACCTCTTGCGATGCAGTACCGATACACTCGCAAGATGACAGCAAGAGCATGGAGGCTCTTCGTCGGTCCAAGAGGCTCATCCAAGAGCAGACGACCGTCCAAACTGAAATAAACTGTGAAGACTGCAACAACTCTGCAGACCAGAGCTGCCCCCAACACGCGGTACAGTCCATCTCGGACAAACCAGTTCCTTCTCGGGCATGGGCTACATTACCTGCAACTTACCTGGCTATCAATAAGACGGAGACTCTGAATAACGGGGAGCCAGTGTGGGGGGTGTTTGCACGCAAGACTATCCCCAAGAGGACACAGTTTGGACCAATCAAGGGAGTCTTGTTGAAGGACTCGTGCAGTGCCGTCTGCTCGGAAGAAGTCGGCTCCCAGCAGGTTCGACTTCTTGTCGAAAGCGATGCAGGGGAGATACACTCCCTGGATGTATTTGACGAGAACTTGTCCAACTGGATGAGGTTTGTGCGAGGGGCGGAAACTCTCAAGGAACAGAATATGATCCTCAACCAGCGGGGCTCCTCGCTGTATTTCACGACGACGAGAGTGATTCATCCCAGAGATGAACTGAGGGTGTGGTATAGCTCCTCCTATGCCTCTAAGAGGGGACTCGCCCTTCTCGACAACAGAAAGAAAACTTTAGATGCCGCGGATATGGAGAGCACATGGCCGTGCTTTGAATGTAATGACACATTTTTCACATCTAAAGACTTGCAACGACATCTGAATATTCATGATACAGAAAAGtttccATGCACTTACAGTCTGAAAAAACACCAAATGATGCACACTAGCAACAATCTCCACACTTGCCCTTTTTGCGGGGAAGAGTTCTATTACTTGTATAACAGGAACAGGCACATCAAGAAAAATCACAACAAGCTTTACAAGGACATATCTCCCAAGTCTGGTAACTCCTTGTTCAAGAGAAGGGTGAACAGTAAGGTAAAGTTGATCGACCATGTATCCATCCACGGAAAGGCCAAGATAAAAAGAGGCATCGTCAATCCTGCCAAACCCTGGAAGTGTGAACTTTGTTACAAGTCCTTTGCTACGCAGGACAGGCTACAGCATCACAGGCTGGTCCATGGCTCAGAGGAGTTGAAGCCACTACAGTGCGTCGTCTGTTGTAAGAGGTTCTTAAACAACTCGGCTCTCGCCTGCCATGCCAAGACCCACTCAGaGAAAAAAACTTTCGAGTGTcccatttgtaaattaatatttgagcaTATATTGGAATTGAGAGCTCACGTTCGCATTCATGCAGTTAATGGCTTATTTACATGCCCTCAATGTCATAAGGTGTTTGATGAATACATTCTGATTCGCAAGCACATACAAGCGTTCCACTGTGATCGCAAACATACATGCTCGTACTGTGAAAAACTATTCCATACGTTGGATAAACTCAGAATGCATATGCTCAGGCACTCCGACCACCGTGAGTTCCTATGCGCGCACTGCGGCAAACAGTTCAAACGTAAGGACAAGTTAAAGGAGCACATGACGCGCATGCATTCAGTAGATAGAGAGCTGCGCATGGCTGTTAATACTCCGCGCACCCGAGTCGCCAAGAAATTCATGCCCAAGGTGTCCCCTAACGATTATCACCGGTTCATCTACAAGTGCCACACCTGTCTGGTGGGGTTCAAGCGCAGAGGCATGCTGGTGAATCATCTGGCTAACAGGCACCCCGACGTCAGTCCTGACTCGGTGCCCGAACTAAACCTGCCCATCCTCAAGACTACCAGGGACTATTTCTGCCAGTACTGTGACAAGGTGTACAAGAGCAGTTCAAAACGTAaagtacatattttgaaaaaccaccctggtGCTGAACTACCCATGAGCAATAGAAGAAAGGGTGGGGTGCCAGATATCCCGGGGCTACCCAACCCGACATTTTCCCAGACCGTGGGCAGTGTGACGACTCACCCTCATGGCTGTCCTTGGTGTCACAAGCAGTACGCCTCCAAGGCCAAACTGCTGCAACACCAGAGGAAAAAACACACAGATCTGCTAACACAAACACAGCAGCCGTCGTCTGAAGACGGAGATAAGAATGTGTCCTCCCCTTCAGCCGGCAACCTGGAGGTTGCAGAGTCCGGGACACAGATTCAGCTGCAGCTGCAAGGACTGGATTCGATCAACCTTCTGCCAGGTGACTACCAGATCACGGCCACCCAGGAGGAGCTCAGAGAGTTCCAGGAGTCAGGGTTATTTATCGATGCCTCGCTGCTAAAACGGCCAATAAAGGGTCTTCCAGACGGCTTGTCGGCCGACTTACTGTCGCAAGCCATGTCCGAGCTCAGTCAATCCATAGGCGAGTTCCGCCTGTCCATGGGGACACCCCCCCATGACCACTACTTTAAAATAGTCCACTCTTCCCCGGGCCATATCATGCTAACATCGGCCAGCTCCCTCCCCTCTCCGTCAGAAACCCCTGCCCCCCCTGATTCTGACCCTATTTTGGAAGGATCCTACTCTCCCCCCACTTCATGGGCCAACACCCAAGTCGCTTACACCCCCTACACCGCACGCTGA
- Protein Sequence
- MDTSSSPQKVPGDEDDLAGVIIPNQTEVDLNDWIPVVNSHLDADGKEVAGTSRLLFLTVEYVEEPTGDYGNSGFSSFEPVASFSPHISSSLSEFEQRVSPLDPNMSSAACYSPVYTIDQSPTTADVNQSSNPSSPFQNQMVVLPNPTSPLISSSTPSSALSPSGQTFVDTSHSTVSLTGGRIIHTYVTHLSSPDSTLPILSQSETEDGKGLLQEVEMGGTFYHESPTGGSPHSSGSENYVVSSSGTLLNAIPSSAADFVEAISINVDASPPGVVDSTSDLLMHSSQLVPGAEFSELTAGGTMVLTSPNQKRDPGALEHFQVVISSSDGENIAYSIDGQTTYINSAQIRADLLNAARAGATTFEDLEAVINLFKSHGVIIEGVDESELRGEQLQESLNINEVNLELTSEPPEFINSTLLGSSVDLAMRREVHLDPEILKEGVMASHSLELTKESFCEDLLMEGTSCDTKPIDLQEDSKDLPMEQAPCDAITIHSQEDNKNLMVEQTSCDAVPIHSQDDSKSMEALRRSKRLIQEQTTVQTEINCEDCNNSADQSCPQHAVQSISDKPVPSRAWATLPATYLAINKTETLNNGEPVWGVFARKTIPKRTQFGPIKGVLLKDSCSAVCSEEVGSQQVRLLVESDAGEIHSLDVFDENLSNWMRFVRGAETLKEQNMILNQRGSSLYFTTTRVIHPRDELRVWYSSSYASKRGLALLDNRKKTLDAADMESTWPCFECNDTFFTSKDLQRHLNIHDTEKFPCTYSLKKHQMMHTSNNLHTCPFCGEEFYYLYNRNRHIKKNHNKLYKDISPKSGNSLFKRRVNSKVKLIDHVSIHGKAKIKRGIVNPAKPWKCELCYKSFATQDRLQHHRLVHGSEELKPLQCVVCCKRFLNNSALACHAKTHSEKKTFECPICKLIFEHILELRAHVRIHAVNGLFTCPQCHKVFDEYILIRKHIQAFHCDRKHTCSYCEKLFHTLDKLRMHMLRHSDHREFLCAHCGKQFKRKDKLKEHMTRMHSVDRELRMAVNTPRTRVAKKFMPKVSPNDYHRFIYKCHTCLVGFKRRGMLVNHLANRHPDVSPDSVPELNLPILKTTRDYFCQYCDKVYKSSSKRKVHILKNHPGAELPMSNRRKGGVPDIPGLPNPTFSQTVGSVTTHPHGCPWCHKQYASKAKLLQHQRKKHTDLLTQTQQPSSEDGDKNVSSPSAGNLEVAESGTQIQLQLQGLDSINLLPGDYQITATQEELREFQESGLFIDASLLKRPIKGLPDGLSADLLSQAMSELSQSIGEFRLSMGTPPHDHYFKIVHSSPGHIMLTSASSLPSPSETPAPPDSDPILEGSYSPPTSWANTQVAYTPYTAR*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01445100;
- 90% Identity
- -
- 80% Identity
- -