Basic Information

Insect: Timema genevievae
Gene Symbol: -
Assembly: GCA_902155825.1
Location: CABFWO010003210.1:51029-62660[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 29 1e-05 0.0019 20.5 2.4 1 23 57 79 57 79 0.97

2 29 0.00017 0.031 16.7 2.5 1 23 85 107 85 107 0.97

3 29 0.00015 0.028 16.8 1.7 1 23 113 135 113 135 0.97

4 29 3.3e-06 0.00061 22.0 1.0 1 23 141 163 141 163 0.98

5 29 4.8e-06 0.00089 21.5 0.7 1 23 169 191 169 191 0.98

6 29 0.0011 0.21 14.1 4.4 1 23 201 223 201 223 0.98

7 29 0.00043 0.081 15.4 0.2 2 23 230 251 229 251 0.96

8 29 1e-06 0.0002 23.6 0.5 1 23 257 279 257 279 0.98

9 29 4.4e-06 0.00082 21.6 1.3 1 23 285 307 285 307 0.97

10 29 1.1 2.1e+02 4.6 0.7 2 23 358 379 357 379 0.95

11 29 0.0035 0.66 12.5 0.0 5 23 390 408 389 408 0.96

12 29 0.0039 0.73 12.4 2.2 1 23 452 474 452 474 0.98

13 29 0.46 87 5.8 2.1 1 23 480 502 480 502 0.92

14 29 4.5e-06 0.00085 21.6 4.2 1 23 508 530 508 530 0.98

15 29 0.00068 0.13 14.8 2.3 1 23 540 562 540 562 0.97

16 29 2.7e-05 0.0051 19.1 0.3 1 23 568 590 568 590 0.98

17 29 1.7e-07 3.2e-05 26.1 1.7 1 23 596 618 596 618 0.99

18 29 8e-06 0.0015 20.8 0.9 1 23 624 646 624 646 0.99

19 29 0.00027 0.051 16.0 4.6 1 23 652 674 652 674 0.98

20 29 0.00077 0.14 14.6 0.5 1 19 719 737 719 739 0.96

21 29 0.021 4 10.1 5.5 1 23 747 769 747 769 0.97

22 29 0.87 1.6e+02 5.0 0.5 3 23 775 795 775 795 0.97

23 29 0.08 15 8.2 0.7 2 23 802 823 801 823 0.89

24 29 9e-07 0.00017 23.8 2.2 1 23 829 851 829 851 0.98

25 29 0.14 26 7.5 1.2 1 23 861 883 861 883 0.90

26 29 0.00085 0.16 14.4 0.1 1 23 889 911 889 911 0.97

27 29 6.9e-06 0.0013 21.0 0.6 1 23 917 939 917 939 0.98

28 29 0.00014 0.027 16.9 0.8 1 23 945 967 945 967 0.98

29 29 4.3e-05 0.0081 18.5 2.4 1 23 973 995 973 995 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	29	1e-05	0.0019	20.5	2.4	1	23	57	79	57	79	0.97
2	29	0.00017	0.031	16.7	2.5	1	23	85	107	85	107	0.97
3	29	0.00015	0.028	16.8	1.7	1	23	113	135	113	135	0.97
4	29	3.3e-06	0.00061	22.0	1.0	1	23	141	163	141	163	0.98
5	29	4.8e-06	0.00089	21.5	0.7	1	23	169	191	169	191	0.98
6	29	0.0011	0.21	14.1	4.4	1	23	201	223	201	223	0.98
7	29	0.00043	0.081	15.4	0.2	2	23	230	251	229	251	0.96
8	29	1e-06	0.0002	23.6	0.5	1	23	257	279	257	279	0.98
9	29	4.4e-06	0.00082	21.6	1.3	1	23	285	307	285	307	0.97
10	29	1.1	2.1e+02	4.6	0.7	2	23	358	379	357	379	0.95
11	29	0.0035	0.66	12.5	0.0	5	23	390	408	389	408	0.96
12	29	0.0039	0.73	12.4	2.2	1	23	452	474	452	474	0.98
13	29	0.46	87	5.8	2.1	1	23	480	502	480	502	0.92
14	29	4.5e-06	0.00085	21.6	4.2	1	23	508	530	508	530	0.98
15	29	0.00068	0.13	14.8	2.3	1	23	540	562	540	562	0.97
16	29	2.7e-05	0.0051	19.1	0.3	1	23	568	590	568	590	0.98
17	29	1.7e-07	3.2e-05	26.1	1.7	1	23	596	618	596	618	0.99
18	29	8e-06	0.0015	20.8	0.9	1	23	624	646	624	646	0.99
19	29	0.00027	0.051	16.0	4.6	1	23	652	674	652	674	0.98
20	29	0.00077	0.14	14.6	0.5	1	19	719	737	719	739	0.96
21	29	0.021	4	10.1	5.5	1	23	747	769	747	769	0.97
22	29	0.87	1.6e+02	5.0	0.5	3	23	775	795	775	795	0.97
23	29	0.08	15	8.2	0.7	2	23	802	823	801	823	0.89
24	29	9e-07	0.00017	23.8	2.2	1	23	829	851	829	851	0.98
25	29	0.14	26	7.5	1.2	1	23	861	883	861	883	0.90
26	29	0.00085	0.16	14.4	0.1	1	23	889	911	889	911	0.97
27	29	6.9e-06	0.0013	21.0	0.6	1	23	917	939	917	939	0.98
28	29	0.00014	0.027	16.9	0.8	1	23	945	967	945	967	0.98
29	29	4.3e-05	0.0081	18.5	2.4	1	23	973	995	973	995	0.99

Sequence Information

Coding Sequence: ATGCAAGACAAGATAAAAAGTGTAGTCAGAAACTCAAGTCGATACACCACAAAGGACGATACCGTGGATACACAGAAGTACTGCTCACCATCGGATGGTGTTAAGCTTATATCTGATCGAATTGGATTATCGGTAAGCCTGAGGAGTGGTACAGGCGATGTACCCAATTACAACTGCGGAATATGTGGGAAAGTATGCGTGTCCAAGGGCCACCTTAAAAGACATCAGGTGTCGCACACAGACGATAGACCGTACCACTGCGACATTTGCGACCGCAACTACAAACGGGCCTTCGAGTTACGCAAACACAAAGAGATCCACACGGGAGAAATGGACCACGTCTGCGACATTTGCGGCTATGCCACCTTCCGCAAGTCGAACCTTCTTGTGCACAAGAAGAGACACTTAAATGATTACAAGTTCAAATGCGACACTTGCGGCAAAGGGTATTATTCCAACACCGAGCTCCAGCGTCACATGACCATACATACCGGTGAACGCCCCTTCCAATGTGACGTGTGTGGCCGGGCGTACCCGTACAAGAGTAACTTAGCGACCCACAAGAAAAAGCACAAcccaaattataaaaacaacttaaagTATCAGTGCGAGTTTTGTGGCAAAACGTTTCTCCACAACAATTCGTTGCGTATCCACAGGAAGTATCATCTCGGGGAAAACCAATTGATGTGCGATGTTTGCGGGAAAACCCTCTCTGGTGTAGACTCGCTTAGGACTCATCGGCGGATACACACTGGAGAGAAGCCATTCTCTTGTGACCTTTGCGGTAAGGAGTTCAGTAAACCCGACTATCTGAAGGTTCATCGGCGAATCCACACTGGAGAGAAGCCTCACCCTTGCGGCGAATGTGGCAAATCATTCACTCAGCTCTCCACGCTCTCTGTTCACAAGAGGAATCACTCCGGACTCAAACCGTACCAGTGTCAGATGTTCAAAATCATTTCGGTAAAAACTGAAGGAAAGGCAGGCTCAAAGGGGAAACCTATAAAGATACCTCAAGATCGCAACTCACTATCGAAGCGCAAGCGATCCAACAGAAAAGATCCGTTGAAGTGCGTGTCTTGTCCCTCGAGTTTCACTACGTTTATCCGGTACAAGGAACATGTAATGTCTCACTCGAGCGGTGCTGTCGCGATGGTGTATGATGTTTGCGGGGAGAATTTCAGCAACCCGGCCGGGTTGATCTGGCATCGCAGGTTGCATAGCGCTAGTAGAGGTAGAACTACTAAAACACCTACCCCGTGTGAAGCCCCAGAGCCAAGTAATTCCTCACAAAGAGCTACACATCCGACGGTGAGAGACCCGCGAAGAAGGGCCATAGGACTGAAACGGCACACGTGCGATATTTGCGGCTATTCCAGCAAGAGCAAGTCCTTTGTAGCCATGCACAGGAAGATGCACTACAACGAATACAAGTTCTACTGCAGGATATGCTCTAAAGGATACAACTCGGTTAAGTTACTTCACGACCACGAGTTTCTACACACCGGCGTCAAAGCTTTCCAATGTGACCAGTGCGGGAAAAGGTTTTCTTCCAGGCACAATTTAGAATCTCATAAAAAGCTTCACATACAAGATTTTGTGGATAACCCTAATTTCTATTGCGAATTTTGTGGCAAGAGTTTCCTGTACAGCAAGTCTTTGAGGAGGCACCGAGACATTCATTTGGGGGAGAATAAATTTGAATGTGATATATGTGGTAAGATGCTGAACTCTAAGGAGTATATGAAGGTTCACTTGCGAATACACAAAGGAGATAAACCTTATGTTTGTGATATGTGCGGTAAGGCCTTTGTCACGAACAAGCACTTGACGATTCATCGACGCACGCACACGGGGGAAAAGCTCTATACCTGCGGGGTGTGCAACAAGTCATTCACGCAGGTTGGGTACTTGACGATCCACAAACGCTCACATACGGGCGAGAGGCCGTACCACTGTGATGCTTGCGGAAAAGACTTTGCCTCCAAATGTCAGCTAAACTCTCATCGAAGAACTCATTTAAGCGTCAAGTTAAAACATGtacataataatttacctaAAGTACGGAAATGGAAGAGAGTCTCCACTGCGCCAGCAAATGTCCTGGGTTCTTCTATAGACACCCCTAGCGATTGGGGCAGGATCAAGATCTATAAATGCAACGTTTGCGGTAAAATCTGTAAGACCCTGGCCCTTCTCAGGGAGCACGCATACTGTCACGTCACTGAGAGGTCCTTTTCTTGTGACTTGTGCAACAAGAAGTTCAAATCAAAGAAACGCATTCACAACCACAGGCAagttcactttaaaaaacactGGTGTGATATCTGTGGGTATACCTCCGAGAAGAAAGTGTACATAGACACTCACAAAAAAatgcattataatatttacaaccTCTACTGCGGCACATGTTCGAAAGGTTTCAATACCGAGAAGTTGCTTCATATACACGAAGGGCTACATACCGGGGTGAAGCCTTTCAAATGTGATGAATGTGAGaaagcgttcacttctaaatataatttattgaaacacaAGAGACTTCACGACCCCACGTACATAAACAGTCCAAAATACTACTGTGAGTTTTGTGATAAATCTTTCCTGTACGTTACTGTGCTGAACAAGCACAGGAGCGCCCATCTTGGCGAGAACAGGTTCGAATGTGACCTGTGCGGGAAGGTCGTCAACTCAAAGGCGTCCATTAGAACTCACTTGCAGGCTCACAGTGGAGAGAAGCCCTTTGTCTGTGATGTGTGCGGCAAGACGTTTTTGACAAACAAGAACTTGGTGGTGCATAGACGGACGCATACGGGGGAAAAGTTGTACTCTTGCAGCATGTGTGAAATGTCGTTCACACAGGTTGGCTATTTGAACATCCACAAACGCTCACATACGGGCGAGCGGCCATACCGCTGCGATGCGTGCGGAAAGGACTTCGCTTCTAAGTGTCAGCTGAACTCTCACCAGAAAATGCACACCGGTGTCATGTGA
Protein Sequence: MQDKIKSVVRNSSRYTTKDDTVDTQKYCSPSDGVKLISDRIGLSVSLRSGTGDVPNYNCGICGKVCVSKGHLKRHQVSHTDDRPYHCDICDRNYKRAFELRKHKEIHTGEMDHVCDICGYATFRKSNLLVHKKRHLNDYKFKCDTCGKGYYSNTELQRHMTIHTGERPFQCDVCGRAYPYKSNLATHKKKHNPNYKNNLKYQCEFCGKTFLHNNSLRIHRKYHLGENQLMCDVCGKTLSGVDSLRTHRRIHTGEKPFSCDLCGKEFSKPDYLKVHRRIHTGEKPHPCGECGKSFTQLSTLSVHKRNHSGLKPYQCQMFKIISVKTEGKAGSKGKPIKIPQDRNSLSKRKRSNRKDPLKCVSCPSSFTTFIRYKEHVMSHSSGAVAMVYDVCGENFSNPAGLIWHRRLHSASRGRTTKTPTPCEAPEPSNSSQRATHPTVRDPRRRAIGLKRHTCDICGYSSKSKSFVAMHRKMHYNEYKFYCRICSKGYNSVKLLHDHEFLHTGVKAFQCDQCGKRFSSRHNLESHKKLHIQDFVDNPNFYCEFCGKSFLYSKSLRRHRDIHLGENKFECDICGKMLNSKEYMKVHLRIHKGDKPYVCDMCGKAFVTNKHLTIHRRTHTGEKLYTCGVCNKSFTQVGYLTIHKRSHTGERPYHCDACGKDFASKCQLNSHRRTHLSVKLKHVHNNLPKVRKWKRVSTAPANVLGSSIDTPSDWGRIKIYKCNVCGKICKTLALLREHAYCHVTERSFSCDLCNKKFKSKKRIHNHRQVHFKKHWCDICGYTSEKKVYIDTHKKMHYNIYNLYCGTCSKGFNTEKLLHIHEGLHTGVKPFKCDECEKAFTSKYNLLKHKRLHDPTYINSPKYYCEFCDKSFLYVTVLNKHRSAHLGENRFECDLCGKVVNSKASIRTHLQAHSGEKPFVCDVCGKTFLTNKNLVVHRRTHTGEKLYSCSMCEMSFTQVGYLNIHKRSHTGERPYRCDACGKDFASKCQLNSHQKMHTGVM*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01444983;
90% Identity: iTF_01444983;
80% Identity: -