Tgen010809.2
Basic Information
- Insect
- Timema genevievae
- Gene Symbol
- Rfx2
- Assembly
- GCA_902155825.1
- Location
- CABFWO010000562.1:102657-168840[-]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.6e-37 2.9e-33 116.3 0.0 3 78 334 409 332 410 0.97
Sequence Information
- Coding Sequence
- ATGACGACGACACAGCAGCCGGCATTCAGCATGGCGTCATCGGTGGCTCCCGTAGACGTCCAACAGGCAGGCTCAGGGCAAGGTGGTGGGGGTAGGCCCGGTAACCAGCAGCAACCTGGTGGAGGGGTAGCGGGCCTTAGTCCCACTGCGACTGTCACCGTGGTCACCAATCCCTCGCAGGTCCAGGCCATCGTCGCAGCAGCAGCAGCGGCTGCCGCCAACACTGTCACTATTACACCTGTCGGTCATCAATCCTTGCAGCAGAACGGGAGTATCGAAGTGTCCTTAGACAGCCCAGAGGATTCAAACGGTGGTGGTGCTTCCAACGGTAGTGTGGGCAGTGGTGGAGCCTCCCAAGTGACGGCACAAGTGGTAGTTAGCAGCGGCGCGGAGGCTGCAACCGCCGGTGCAGAGCAAGGCGGAGCAGGAGCTGCAACTATTGTCGGCTCTCCTCATTACATCACTGTAACAGAGGGTAACGGTTCAAGGTCATACACAGCCCTCACACCAGTTAACCCTGTTGTAGCAGTGTCGGAAGGAGACGCCGTGGGGACGGACGCAGTGGCGCAAGGGGTGCACCCCACGTACGTGCAGTATGTAGAAGGCTCGGCAGATCAGGCCATCTACGCTGCCACCAATGGACAGATGGCCTACCCAGTATACACGGTGGGGGAGACGGGGACCATGTACACTCCTGCCACCGGCCAGTATTACACCGGCAACTCCACCGCCGTCACCTACAGCCAGGTGGCGGGCAGCCTGGCGCAGGGTGGGGCAGCAGGCCAACTCCTGGCCCAAGGCAATGGAGCCTACCTCATCCAGCAAGGGGTGGATCCTGAAACCGCTCACTCCATCATAGCTGCTCAGAGAGCCTCCCCGCAGACTGTGGCGGCTGATGGCAGTGGTGGGGTGGCGTACATGGTCCCTGGGAACTCAAACCCCTCCTCCATGGATGGTGACGGTCATCCCAGCCTCTCCCATGCCACTCGAGTGTCGCCAGCCACTGTTCAGTGGCTTCTGGAGAACTACGAGACTGCAGAGGGGGTGAGTCTGCCCCGATCCACCTTGTACAACCACTATCTCCGCCACTGTAGTGAACATAAGCTTGACCCAGTCAATGCTGCTTCCTTCGGTAAACTGATTCGCTCCGTGTTCCTCGGCCTGCGCACTCGTCGACTCGGCACCAGGGGAAACTCAAAGTATCACTACTACGGTATTCGCGTGAAGCCGAGTTCCAGTTTGAACCAACTCTCAGAAGATGGCACCTCCCTCTCTTCGAGCCGACAGCAAGGCGGTTCCTCACAAAAACGCTTCAAGTTCCTGCCGGGCTCCGGCCAGAAGATGGAGGGTCAGTATGAACAAGGAGGTGGCGGTAACAACACGTCATCCAATCACTCGAGCTCCGCTTCCCCGCCACAGCATCACCAGTACCTTGGGGACGGGGCTGGGGCtatccctgactttccagagaTTGACTTCTCCCCAGGACTGAGCCTACCTGAGGACTGTACTCTAGAAGATGTGGACACACTGCGGAGTATCTACAGGGAACATTGCGAGGCGTTCCTCGACGCAGTGGTAAACTTGGAGTTTCAGACTGTAGAGAGTTTATGGCGGGAGTTTTGGCGCAGTCAAGATAACAACAATGGGGATGAGTGTGAAGAAGAAAAGTATCTATCCAAAACTAAGCTCTACCTGCTGTGCAAATGTCCTCCTGTGCTGTTGTTTGTTCGTCGGGTAGACTACCTTTTCTACCAGAATCTAGTCGAAGTCCTAATACCAGATGTCCTCAGGCCTATTCCTAGCTCCTTGACGCAAGCCATCCGCAACTTTGCCAAGGGCCTGGAGTCTTGGCTGACTCAAGCCATGCAGGGATGTCCTGAAGAAATGATGCACATCAAGGTGTCTGCAGTGAGTGCCTTCGCTCAGACGCTACGCCGCTACACCTCGCTCAACCACCTAGCCCAGGCAGCTCGTGCTGTACTGCAGAACTCTGCGCAAATCAACCAGATGTTGGTTGACCTCAATCGAGTCGACTTCCACAACGTGCAGGAACAAGCCTCGTGGGTGTGCCAATGCGACGATGATGTAGTGCAGCGTCTTGAAGCAGACTTCAAGGTTACACTGCAGCAGCAGAACTCACTGGAGCAGTGGGCAGCATGGCTCAAAGGGGTTGTCACGCAGATCCTCAAACCCTACGAAGGGAAACCCAACTTTTCCAAAGCTGCCAGACAGTTCTTGCTCAAATGGTCCTTTTACAGCTCTATGGTAATCCGTGACCTGACTTTGAGAAGTGCAGCAAGCTTCGGCTCGTTTCACTTGATCCGACTGTTGTATGATGAGTACATGTTCTTCCTCATAGAGCACCAGGTGGCCCTAGAGACGGGGGAAACGCCCATCGCTGTTATGGGAGAGAAGTTCAATAACAATCCGTCCAGCGTGAGCGGCTACTCTCAGCCGCAAAGCTCGTGTAACGGGGGCATGGCGCTAACCATGGGTCTGCCCATGGAAACTAAGCTTCTCCCAGGAACCACTCTTTTGTTAACAAGTAGCGACGTCGGTCACCACTCTACTACCAAACGACTCAAGATCAGCTAA
- Protein Sequence
- MTTTQQPAFSMASSVAPVDVQQAGSGQGGGGRPGNQQQPGGGVAGLSPTATVTVVTNPSQVQAIVAAAAAAAANTVTITPVGHQSLQQNGSIEVSLDSPEDSNGGGASNGSVGSGGASQVTAQVVVSSGAEAATAGAEQGGAGAATIVGSPHYITVTEGNGSRSYTALTPVNPVVAVSEGDAVGTDAVAQGVHPTYVQYVEGSADQAIYAATNGQMAYPVYTVGETGTMYTPATGQYYTGNSTAVTYSQVAGSLAQGGAAGQLLAQGNGAYLIQQGVDPETAHSIIAAQRASPQTVAADGSGGVAYMVPGNSNPSSMDGDGHPSLSHATRVSPATVQWLLENYETAEGVSLPRSTLYNHYLRHCSEHKLDPVNAASFGKLIRSVFLGLRTRRLGTRGNSKYHYYGIRVKPSSSLNQLSEDGTSLSSSRQQGGSSQKRFKFLPGSGQKMEGQYEQGGGGNNTSSNHSSSASPPQHHQYLGDGAGAIPDFPEIDFSPGLSLPEDCTLEDVDTLRSIYREHCEAFLDAVVNLEFQTVESLWREFWRSQDNNNGDECEEEKYLSKTKLYLLCKCPPVLLFVRRVDYLFYQNLVEVLIPDVLRPIPSSLTQAIRNFAKGLESWLTQAMQGCPEEMMHIKVSAVSAFAQTLRRYTSLNHLAQAARAVLQNSAQINQMLVDLNRVDFHNVQEQASWVCQCDDDVVQRLEADFKVTLQQQNSLEQWAAWLKGVVTQILKPYEGKPNFSKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFFLIEHQVALETGETPIAVMGEKFNNNPSSVSGYSQPQSSCNGGMALTMGLPMETKLLPGTTLLLTSSDVGHHSTTKRLKIS*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01444453;
- 90% Identity
- iTF_01445392;
- 80% Identity
- -