Basic Information

Insect: Timema douglasi
Gene Symbol: -
Assembly: GCA_901482245.1
Location: CABEEJ010006412.1:11229-27139[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.0002 0.046 16.4 1.6 1 23 602 624 602 624 0.96

2 17 0.0092 2.2 11.2 0.6 2 20 641 659 640 661 0.92

3 17 0.13 31 7.6 0.4 1 10 669 678 669 691 0.88

4 17 0.014 3.3 10.6 3.7 3 23 699 720 698 720 0.95

5 17 0.00055 0.13 15.0 9.6 1 23 726 748 726 748 0.98

6 17 0.0047 1.1 12.1 3.7 1 23 754 776 754 776 0.98

7 17 0.011 2.6 10.9 6.5 1 23 782 804 782 805 0.96

8 17 0.001 0.24 14.2 2.1 1 23 820 842 820 842 0.97

9 17 1.3 3.1e+02 4.4 0.3 1 23 859 882 859 882 0.92

10 17 0.067 16 8.5 0.4 1 23 888 910 888 910 0.98

11 17 0.025 5.8 9.8 0.4 2 23 934 955 933 955 0.96

12 17 0.3 71 6.4 4.8 1 23 961 983 961 983 0.99

13 17 1.8e-06 0.00042 22.9 0.8 1 23 989 1011 989 1011 0.95

14 17 0.041 9.8 9.1 1.2 1 23 1017 1039 1017 1039 0.97

15 17 0.032 7.7 9.4 2.2 1 23 1045 1067 1045 1067 0.96

16 17 1.4e-06 0.00034 23.1 1.2 1 23 1073 1095 1073 1095 0.98

17 17 0.00014 0.034 16.9 0.5 3 23 1103 1123 1102 1123 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.0002	0.046	16.4	1.6	1	23	602	624	602	624	0.96
2	17	0.0092	2.2	11.2	0.6	2	20	641	659	640	661	0.92
3	17	0.13	31	7.6	0.4	1	10	669	678	669	691	0.88
4	17	0.014	3.3	10.6	3.7	3	23	699	720	698	720	0.95
5	17	0.00055	0.13	15.0	9.6	1	23	726	748	726	748	0.98
6	17	0.0047	1.1	12.1	3.7	1	23	754	776	754	776	0.98
7	17	0.011	2.6	10.9	6.5	1	23	782	804	782	805	0.96
8	17	0.001	0.24	14.2	2.1	1	23	820	842	820	842	0.97
9	17	1.3	3.1e+02	4.4	0.3	1	23	859	882	859	882	0.92
10	17	0.067	16	8.5	0.4	1	23	888	910	888	910	0.98
11	17	0.025	5.8	9.8	0.4	2	23	934	955	933	955	0.96
12	17	0.3	71	6.4	4.8	1	23	961	983	961	983	0.99
13	17	1.8e-06	0.00042	22.9	0.8	1	23	989	1011	989	1011	0.95
14	17	0.041	9.8	9.1	1.2	1	23	1017	1039	1017	1039	0.97
15	17	0.032	7.7	9.4	2.2	1	23	1045	1067	1045	1067	0.96
16	17	1.4e-06	0.00034	23.1	1.2	1	23	1073	1095	1073	1095	0.98
17	17	0.00014	0.034	16.9	0.5	3	23	1103	1123	1102	1123	0.95

Sequence Information

Coding Sequence: ATGGATGAATCGGCCGACACTGTCAAGATGGTGTTGAAAAGTGACACCGGGGACTCTGTAACTGTCTGTATGTACCCAGACAACGCTTTCGAAGCGTTCAGCAACAAGTTCCATAACCATCTTGACCTACCGTTGGATTGCCAGTTGAAAGTGGAGGACAGCCATTTCTTGACAAAAGAAAAAGATTCAGAACTGTTGTTTGGTGATCTTAGCCCAAGTCTTGGGTTGATTTCCTCCGTGAGTGATGTCACCGATGTTACATTTGTGAGCACAGATCCGGAGACACACTCTATCACAAGTGATAACAACTTTGTCATGTCACCAGTCCAGCAGTTGGTGTACCCCCAAGATGTGAGGAGCTGCATGAAGCCAGAGGTGTCTTATGACTCGTGTTCACCTGCATGGAGCAAAGTGGTCTCGTTTAGATGTGCGGTTCCAACATGTGTCAATACCAAGGACACCTGGCCCAGGAAGAAGTTCTTCAAGTTCCCCATTGCCAAAGATAGGTGTCATCAGTGGCTGCAGCTTTGCAGGCGGGAAGACCTTCTCGAGGAGCCCAGTGAAATGGTTGGCAGCCTCTATGTTGTGTGTTCAGATCACTTCATTCAAGACCACTTTGTGACGGTGGCTCGTAAAGCTCTGACCAAAATGGCAGTGCCAACAATATTTCCTGCTTCTGACGATATACTGGCAAAACAGTCTGTAAATACCAAAGGTTCAGAAAATGAAAGTATACACTCTGAGGAGAGAGAAGAAGATGACATCGTTGATGATgatgttttttatgtttgtgaTAGTGATACTGGAGATTTAGGAGAGTTAACGGGACTGCAGAAATCATATTTGGACAGGAACAGCAGCAGTTCCGACTCTGAGACGGATGTAGACTCCCTCGGTCAATTGTGCAGACTTTGTGGGTGTGTTTCTGAGGATGCAGCATACATCTACGGCAGCACCGAGGAGGATTTGGGGCTCGCGACCAAGATCAACACCTTGCTGCCAATCATTGTTGAGAAGAGTGACCCACTTCCCAAGCAGGTGTGTATGGACTGCCTCTCTAAATTGAATACCTGCTTTGAGCTAACTAAATCATGTCTCAGGACAGACCGATGGTTGAATCGTTTGAGGAGGAAGAAACTCTTCAGGAGTCATACTTTAATGAAAGTTCATCCTGGAGAAGTTTCTCAGAAAAGTAACAATGGTTTCATAAAACTAGAAGTAACTAATTCCACATCTCTTTGTGAGCAGACAAACAATTCTACCGATgtcaaaaaaaagtatgatgAAGATAACTTTAACAATAGCGCCATTGAAAAGTTGGTTACAAGTTGTTATTCTTGTCCGTTTTGCTCATATGGTACCATGATCATGCAAAAAACTTCATCTCATGATTCAACTTTAGAATGCGGAGACATAAAAACAACAGAGCAAAGTATTAACTCTAGTGACTTACCAAATGATAAATCCACAAAACAAATGTTGAACAAAGACTCTGTTTCCACAAGTGATACAGAAATACATCCTGAGCTACcgaatttattttatgaagtcAGAGATGAGCATGGGAATAAATATGCAATGGTTGAGCCGACACCGAGTTGGTGGAATGAGGATGGTAATATGGGAAACACTGAGATAATAATCCATGCAGTGAACCCAAATAAATTGAGTGAAGAACCATGGTCGACTTTGAATCATGCAGATGAAAATATTGACCGCCATTGCTGCCTCCTCTGTGGCAATAGTTTCCAGACTCTCGAATTGTGCCTGGAGCACAGCAACTCCCACCTAGACACTGAAGGTTTTGTCTGTAACATGTGTCTCCTTCACTTTTCAAACAAATCTGAACTCACCAGTCACATGGATGATCATCGAGCAGACGAGAAACGTCTCTTGAGAGTGGAAGGTTCTAAACGTCTCATTTGCACTGTCTGTGGCAGGAAGTTTAATAACGAGAGGACATGGAAGGCCCACACTTGTGCCAGTGAACCTTCAAAAAAACTGTTCAAGTGCACAGAGTGTAACAAATCTTTCCTTACTGAGGAACGCCTTACATTCCATGGGATTTTGCACAAGCTCAAGCAACCAAACCACTGCGAGAAGTGTGACAGGCAATTTGAACACAGGAGTGCTTTCTACCAACACTGGCGGCTTGTCCATGAAGGTGAAAGACCGTTTTGCTGCCACAAATGTGGCAAAACATTCTACTCTCACTCAAGGCTGGTCACACACCTACGCACCCACTCAGGTGAACGGCCTTATGAGTGTGATGTTTGTCACCATAAGTTTTATGACAATGAGACACTCAAAGGGCACTATGTCACACACATGAACACAAAGCCATTTCAGTGTCATCTCTGTGGGGCTTTTTGTGGCCGCCGAAGTTTATTCAATCAGCATTTGAAAGTTCACCATAGTAGTCCAAATGGCCCCAAGCGGGCCCCGTCCCTCATACATTATTTCTGTAAGTCATGCAACAAGACATTCACGAGTTCCAACGAAGTGTTGACTCACAGAGCTACCCACTGGCACCGAGAAGAAAAAGACAAAAATCGCGAAGATAATCCTGTGACCCATGATTGTGAGTACTGTGGGAATGGTTACTTGTCCATAGCCGAACTGGCAAAACATCGAAAGCTAGAGCATGCGGAAGAAAAGCCGTACGTTTGTAGCATTTGTAGTGAGTTGACCAAGACACTTTACGAAGCAAGGGCGCACAGGAAAAGTCACACAACAGTGTCAAGTGTTTCAGAGGAATCTGGTGGGAACATGAAGGAAGGGGACAAGTACGCATCATTAGTTTGTGAAGAGTGTGGGGCCCAGTGTGAAGGAAGTAGGAAGCTGAAGGCACATTTGAAGCTACACAGGGCGGAGACAGTCTACCAGTGCGGAATGTGCTGCCGGAACTTCCCCAACCACCGGCGGTTGATTCTGCACCAACGCATGCACTCCGGAGAGAAGCCTTACCCTTGTCCAGATTGTGGTAAGAGGTTCTCTCAATCGTCAGCACTGCACACACATTCGTTACTTCACACAGGAGAGAAACCTCACATATGTGATCTGTGTGACGCTACCTTCAGGATCAAGGCGGACAGAGACAACCACCGGCGCACGCATACCGGAGAGAGACCTTACCGCTGCGAGTACTGCTCCAAACAGTTCCGGACGGGCCAGGTGTATTACCAACACCGCATGATCCACACAGGGGAGCGGCGTTTCCCTTGCAATGTTTGTGGCAAGGCGTTCAAACGCTCCCACACACTCGTGGTCCACAAGCGTATCCATACAGGAGAAAAGCCCAATATCTGCGATGTCTGCGGCAAAGGTTTCCGCCAACGAACGGATATGAGGAAACACAGGGCTCTCCATGGCTCGTGA
Protein Sequence: MDESADTVKMVLKSDTGDSVTVCMYPDNAFEAFSNKFHNHLDLPLDCQLKVEDSHFLTKEKDSELLFGDLSPSLGLISSVSDVTDVTFVSTDPETHSITSDNNFVMSPVQQLVYPQDVRSCMKPEVSYDSCSPAWSKVVSFRCAVPTCVNTKDTWPRKKFFKFPIAKDRCHQWLQLCRREDLLEEPSEMVGSLYVVCSDHFIQDHFVTVARKALTKMAVPTIFPASDDILAKQSVNTKGSENESIHSEEREEDDIVDDDVFYVCDSDTGDLGELTGLQKSYLDRNSSSSDSETDVDSLGQLCRLCGCVSEDAAYIYGSTEEDLGLATKINTLLPIIVEKSDPLPKQVCMDCLSKLNTCFELTKSCLRTDRWLNRLRRKKLFRSHTLMKVHPGEVSQKSNNGFIKLEVTNSTSLCEQTNNSTDVKKKYDEDNFNNSAIEKLVTSCYSCPFCSYGTMIMQKTSSHDSTLECGDIKTTEQSINSSDLPNDKSTKQMLNKDSVSTSDTEIHPELPNLFYEVRDEHGNKYAMVEPTPSWWNEDGNMGNTEIIIHAVNPNKLSEEPWSTLNHADENIDRHCCLLCGNSFQTLELCLEHSNSHLDTEGFVCNMCLLHFSNKSELTSHMDDHRADEKRLLRVEGSKRLICTVCGRKFNNERTWKAHTCASEPSKKLFKCTECNKSFLTEERLTFHGILHKLKQPNHCEKCDRQFEHRSAFYQHWRLVHEGERPFCCHKCGKTFYSHSRLVTHLRTHSGERPYECDVCHHKFYDNETLKGHYVTHMNTKPFQCHLCGAFCGRRSLFNQHLKVHHSSPNGPKRAPSLIHYFCKSCNKTFTSSNEVLTHRATHWHREEKDKNREDNPVTHDCEYCGNGYLSIAELAKHRKLEHAEEKPYVCSICSELTKTLYEARAHRKSHTTVSSVSEESGGNMKEGDKYASLVCEECGAQCEGSRKLKAHLKLHRAETVYQCGMCCRNFPNHRRLILHQRMHSGEKPYPCPDCGKRFSQSSALHTHSLLHTGEKPHICDLCDATFRIKADRDNHRRTHTGERPYRCEYCSKQFRTGQVYYQHRMIHTGERRFPCNVCGKAFKRSHTLVVHKRIHTGEKPNICDVCGKGFRQRTDMRKHRALHGS*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448922;
90% Identity: iTF_01450647;
80% Identity: iTF_01446661;