Tcri008109.1
Basic Information
- Insect
- Timema cristinae
- Gene Symbol
- litaf
- Assembly
- GCA_002928295.1
- Location
- CM009474.1:53367393-53372031[-]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.8 1.5e+04 -2.4 1.6 27 28 19 20 3 42 0.53 2 2 4.2e-27 3.6e-23 82.9 15.4 1 69 120 188 120 189 0.97
Sequence Information
- Coding Sequence
- ATGATGGAACAAGACGTAAAGTGCACTCCCTGTGTCCCCAATCTCTCCAGGATAACTTCAATCCTAGTCCTGTTGCTCCTCGCTACTCTGCCAGCACTGGTGCTCATCAAGTGGTCTAAGGTTCAGGCGCTTGCAACGGACCGGATCACCTGTGTTGGAGAgCCACCAGCGCGCTATCATCGAGGTGTAATCAAGGATCGCTCCCTCAAAGGCCCGCCAGTGGATGCTTATCGCCAGTGGGTGGATAATCGGCCAGTCTGGCCGTGCCCTGAGACGTTGTCCCCACGAGGGTCTCGGGATGTTGATGCACCAAACTGTGTTTTAACTCTTGTTACAGTGAGTTTCGTCGGTCTCGGCCCCCAATCCAGCAGCATCGAGTGTCCGTCCTGTCATCACAGCATACAGACCAGGGTGGAGCACGTCAGCACGACCAGGACCCACCTGATAGCCATCGTGCTCTGTGCTTTCCTgtGTTGGCCTTGCATTTGTGTACCTTACTGCACGGACTCTTGCAGGAATGCCAACCATTACTGTCCGAATTGCAATGCATACATAGGAGCTTATGTCAACTAA
- Protein Sequence
- MMEQDVKCTPCVPNLSRITSILVLLLLATLPALVLIKWSKVQALATDRITCVGEPPARYHRGVIKDRSLKGPPVDAYRQWVDNRPVWPCPETLSPRGSRDVDAPNCVLTLVTVSFVGLGPQSSSIECPSCHHSIQTRVEHVSTTRTHLIAIVLCAFLCWPCICVPYCTDSCRNANHYCPNCNAYIGAYVN*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -