Basic Information

Insect: Timema cristinae
Gene Symbol: -
Assembly: GCA_002928295.1
Location: CM009477.1:49707759-49712246[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.00076 0.11 14.4 0.1 2 23 11 32 10 32 0.95

2 20 0.00012 0.018 16.9 4.3 1 23 38 60 38 60 0.97

3 20 0.00055 0.08 14.9 0.3 1 23 66 88 66 88 0.98

4 20 8.7e-08 1.3e-05 26.8 1.2 1 23 94 116 94 116 0.98

5 20 2.1e-05 0.0031 19.3 5.2 1 23 121 143 121 143 0.98

6 20 6.6e-06 0.00096 20.9 0.6 1 23 152 174 152 174 0.98

7 20 1.4e-06 0.00021 23.0 0.2 1 23 180 202 180 202 0.98

8 20 1.6e-06 0.00023 22.8 0.8 1 23 208 230 208 230 0.98

9 20 2.4e-07 3.6e-05 25.4 3.3 1 23 236 258 236 258 0.97

10 20 3.4e-05 0.005 18.6 2.1 2 23 305 326 304 326 0.96

11 20 0.0029 0.42 12.6 6.9 1 23 332 354 332 354 0.98

12 20 0.2 29 6.8 2.7 1 23 360 382 360 382 0.93

13 20 0.00097 0.14 14.1 1.9 1 23 389 411 389 411 0.97

14 20 2.7e-06 0.0004 22.1 0.7 1 23 417 439 417 439 0.98

15 20 2.3e-06 0.00033 22.3 1.4 1 23 444 466 444 466 0.98

16 20 0.0099 1.4 10.9 1.9 1 20 473 492 473 494 0.92

17 20 1.1e-06 0.00016 23.4 0.3 1 23 501 523 501 523 0.98

18 20 1.9e-05 0.0028 19.4 1.3 1 23 529 551 529 551 0.98

19 20 1.1e-06 0.00016 23.3 2.8 1 23 557 579 557 579 0.97

20 20 0.00012 0.017 17.0 2.9 3 23 587 607 585 607 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.00076	0.11	14.4	0.1	2	23	11	32	10	32	0.95
2	20	0.00012	0.018	16.9	4.3	1	23	38	60	38	60	0.97
3	20	0.00055	0.08	14.9	0.3	1	23	66	88	66	88	0.98
4	20	8.7e-08	1.3e-05	26.8	1.2	1	23	94	116	94	116	0.98
5	20	2.1e-05	0.0031	19.3	5.2	1	23	121	143	121	143	0.98
6	20	6.6e-06	0.00096	20.9	0.6	1	23	152	174	152	174	0.98
7	20	1.4e-06	0.00021	23.0	0.2	1	23	180	202	180	202	0.98
8	20	1.6e-06	0.00023	22.8	0.8	1	23	208	230	208	230	0.98
9	20	2.4e-07	3.6e-05	25.4	3.3	1	23	236	258	236	258	0.97
10	20	3.4e-05	0.005	18.6	2.1	2	23	305	326	304	326	0.96
11	20	0.0029	0.42	12.6	6.9	1	23	332	354	332	354	0.98
12	20	0.2	29	6.8	2.7	1	23	360	382	360	382	0.93
13	20	0.00097	0.14	14.1	1.9	1	23	389	411	389	411	0.97
14	20	2.7e-06	0.0004	22.1	0.7	1	23	417	439	417	439	0.98
15	20	2.3e-06	0.00033	22.3	1.4	1	23	444	466	444	466	0.98
16	20	0.0099	1.4	10.9	1.9	1	20	473	492	473	494	0.92
17	20	1.1e-06	0.00016	23.4	0.3	1	23	501	523	501	523	0.98
18	20	1.9e-05	0.0028	19.4	1.3	1	23	529	551	529	551	0.98
19	20	1.1e-06	0.00016	23.3	2.8	1	23	557	579	557	579	0.97
20	20	0.00012	0.017	17.0	2.9	3	23	587	607	585	607	0.98

Sequence Information

Coding Sequence: ATGAAAACACATGTATCAAACAAAGCGTTGGTTTGCAAAAGTTGCGATAAAGTGTTCACCGCCGTTAGTCTTTTGGCGAAGCACACGGCGAGTCACACGACAGATAGGCCCTTTCCTTGCGACCTCTGTCGGAAGACTTTCAAACGCAAACATGAACTCGTTAGCCACAAGAAGCAACACGAAGGTGTCAAAGATTTTGTATGTGACATTTGCAGCTATGCGACAGGCCATAAAGCCTCGCTTGCCGTGCACATAAAGAGACACACGTGCGAAGCTCAATTCCCCTGCAACGTCTGCAACCGAAGTTTCTACACAAATTCACAACTTCAGAACCATATAAACACTCACTATGGAAAGAAGCATCAGTGCGAGTTTTGCGGCAAGTCGTTTATCCATAAGTACAACATGTTGATCCACCAGAAATCCCACGACCCGTCGAAAGACATAAGGAAATTCCCATGCGAGATTTGCGGCAAAACTTATCAGCGCAGAAACAAACTCATGATGCACATTCGTCTGCACACGGGAGAGATGCGCTACATATGTGACATATGTGGTAAAAGTGTGACGAGCAGTACGTCCCTGGAGACTCACCGAAGGGTCCACACTGGTGAGAAGCCATTCGTCTGCGACCTTTGTGGGAAAGCGTTCAACTCAAACAACTATCTGAGGGTCCATAAGCGTTCGCACACCGGAGAAAAACCTCACATGTGTAAACAGTGTGGAAAATCATTCACTCAGCGCTCCACACTTGTTGTACATATGAGGTACCATACTGGTCAGCGACCGTGTTCACCACAATATGGTGGTGAGTGGTGGAATGAAGGTTTGTGTACATCTCCCGAGTCTCCAAGACCCATAAAGGGGGGACCCCCACTCATAGAAGGTCCGATAAAAAAATCCGAAACTCTGGAATGCGACACGTGTGGAAAGAGGTGTAAGAGTAAAGCTAACCTTAATTTACACTCGAGAGTTCACGACCCTTCGAAACATCACAAGTGTAAAACTTGcgataaaatatttctggatAAGCACCATCTCGCAAGGCACACGGCCACTCACAACAAAGAGAGGCCGTATGCATGCGATGTCTGCGACAAAACCTACAAGTGTCCTTTCAGGCTATCAAGTCATAAAAAAGGTCACTGCGAGAAGAAAAAACCACACGTGTGCGATATCTGTGACTACTCAACAATCTACAGGTACTATCTGGAAATCCACAAAAAAAGACATGCGTCTGACTTTACGTTCAAGTGTGATCTGTGCGGGAAAGGTTATTATACCGCCACAGATCTTAAAAGGCATAGAATGATCCATGACGGGAGTAAACACACATGTGACGTATGTGGTAAAGAGTTTACAATGGATAAAAACCTGAAAGACCATATGAGGATCCATAAATCCAACAGAAGACGTTTCAACTGCGCACTTTGCggtaaaagctatttttatactAGCCAATTAAATGTGCACAACTGCACCAAAGGAGAGGCTGTCAGATACGTCTGTGATGTTTGCGGGAAAACCTTGACGAGTGCGTCGTCCCTTCAGAGCCACCGCCGGCTACACACAGGGGAGAAACCGTTCATGTGTGATATCTGTCTGAAGTCCTTCAACACGGCCACTTACTTGCGCATACACAAGCGCTCACACACGGGGGAGAAGCCCCACGTGTGCAGTCAGTGCGGCAAGTCTTTCACCCAGCGCTCGACGCTTGTCGTTCACTATAGGTATCATTCAGGGGAGCGCCCTTTTGGGTGCCATGTTTGCTCAAAACGATTTGTCACAAGGACCCTTCTTAACACTcacattaaaaatcataaatga
Protein Sequence: MKTHVSNKALVCKSCDKVFTAVSLLAKHTASHTTDRPFPCDLCRKTFKRKHELVSHKKQHEGVKDFVCDICSYATGHKASLAVHIKRHTCEAQFPCNVCNRSFYTNSQLQNHINTHYGKKHQCEFCGKSFIHKYNMLIHQKSHDPSKDIRKFPCEICGKTYQRRNKLMMHIRLHTGEMRYICDICGKSVTSSTSLETHRRVHTGEKPFVCDLCGKAFNSNNYLRVHKRSHTGEKPHMCKQCGKSFTQRSTLVVHMRYHTGQRPCSPQYGGEWWNEGLCTSPESPRPIKGGPPLIEGPIKKSETLECDTCGKRCKSKANLNLHSRVHDPSKHHKCKTCDKIFLDKHHLARHTATHNKERPYACDVCDKTYKCPFRLSSHKKGHCEKKKPHVCDICDYSTIYRYYLEIHKKRHASDFTFKCDLCGKGYYTATDLKRHRMIHDGSKHTCDVCGKEFTMDKNLKDHMRIHKSNRRRFNCALCGKSYFYTSQLNVHNCTKGEAVRYVCDVCGKTLTSASSLQSHRRLHTGEKPFMCDICLKSFNTATYLRIHKRSHTGEKPHVCSQCGKSFTQRSTLVVHYRYHSGERPFGCHVCSKRFVTRTLLNTHIKNHK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01447745;
90% Identity: iTF_01447745;
80% Identity: -