Tbar004547.1
Basic Information
- Insect
- Timema bartmani
- Gene Symbol
- -
- Assembly
- GCA_902151455.1
- Location
- CABFWB010000180.1:379584-394663[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.97 2.2e+02 4.8 0.3 1 23 274 297 274 297 0.92 2 17 8.3 1.9e+03 1.8 2.9 1 21 302 325 302 327 0.92 3 17 0.41 91 6.0 0.2 2 20 546 564 545 566 0.91 4 17 0.018 4 10.3 1.4 1 23 572 594 572 594 0.95 5 17 0.00014 0.031 16.9 6.7 1 23 600 622 600 622 0.98 6 17 2.3e-05 0.0052 19.3 1.0 1 23 628 650 628 650 0.97 7 17 0.00049 0.11 15.1 1.3 1 23 655 677 655 677 0.95 8 17 0.5 1.1e+02 5.7 0.3 2 23 687 708 686 708 0.96 9 17 0.0012 0.28 13.9 1.2 1 23 714 738 714 738 0.96 10 17 6.2e-08 1.4e-05 27.4 3.3 1 23 744 766 744 766 0.98 11 17 0.056 13 8.7 0.4 1 23 772 794 772 794 0.97 12 17 0.00011 0.024 17.2 0.4 1 23 807 829 807 829 0.98 13 17 0.01 2.3 11.0 2.2 3 23 837 857 835 857 0.98 14 17 0.0028 0.63 12.8 0.1 1 23 863 885 863 885 0.97 15 17 1.3e-05 0.0028 20.2 0.3 1 23 891 913 891 913 0.96 16 17 2.7e-07 6.1e-05 25.4 0.3 1 23 919 941 919 941 0.99 17 17 9.3e-05 0.021 17.4 2.6 1 23 947 969 947 969 0.98
Sequence Information
- Coding Sequence
- ATGGCAGCGACGTTAGACTTGAATAAGTTGGGTGTAGTCGCTGGTCAACTCTGCCGAGTGTGTGCAAGGTTGAGTCGGAGACTAACACCAATATTTGGTCAAAAGGGGATAGAAATAGATTTAGCAACCAAGATCCACACACATCTCCCTATTATGGTGACCGAAGATGATTTGATGCCTGTGTGCCTGTGTGAACCCTGCATACATAAGCTACAAGTGTGCCATAATCTTGTCAATACATGTCTGGAAGGTGATATAAGACTCAGAAAAATAATGGGATTGCCTATAGAGCAGGAAGTAACTCCTGAACCAGATTGTGAATTAATAGATTTGGAGAAAGAAGAAGATTTGGAGAAAGAAGAACCTTCCGAGGAAGCTGCAACCCCGGAAGATAAAAACCAAGAGACTGAACACAAGCAATTGCAAGAAGAAAGTGATGATGATTTTCTTTGGGAAGAGGACCAGTCTGCCGTTGATGTcaatcctcctcctcctccaccTGACGAAATCAGGCCTCAAAGAGTTGTCAAGAGGGGAAGACCGAGGAAGTATCCGGTCCCTCAAGAAATCAAACAAGTCTGTAATCCTCCACTTGTATTCTACGAGTCTAAACACGCCTTTGATTTGCACATGTTAAACCATTTGGAAGCAGAGGAAGGAGAAATTCGTACCTGTATGAGTGAGGATGCAAACATTGTTGAGCTAACTAATGAGCATATTGATCAATCAAATACATCCTCAAAAAAACATCAAGCTTCAGAGACTCAAAACAGGTTTACTAGAACCGACTTAGAGCCTGCTCCCAACGATGTATTTTCTTACCTGTGTTCATATTGTAAAGAGACACTGATAGGTACTGATATGTTCCTTGCTCATCAATCCCAGATGCATCCAGATAAAGTGTTTACATGCACTATATGTAAGCCCCATGTTGTGTTCTACGAGACTAAAGAGCTGTTTGAGCGACACATGCTTTGTCATCCACAAGAAATCATAGAAAGGGATGATTCATTGGAGGAAAGTGTAATCACAGACCTAGATAAACCAGCAACTGAGGATTATGCTGAGACCTTGCCTACAGGAACTACTGATGAAAATGTATCCGTTTCTATTCCTGATGATGCATCTGATCTTATCACTGCTTCAAATGAAGTTGCTGGCTCTTCTGCCTGTCCTGTTGATGTCTCTACTCTTGTTAAAGATGATTCTGAAAATAACTTCTCTTTTGTTGATGCATCCATTCCTTATCAAGAGAATCCTGTTGACACCTTTACTTTTGCTGATGCAGAAATTCCTGCCATTAAATCTAATGTTACTGATGTTACTACTAGTGATCCAAGCCCTAAGCAACCTGATAACTTGGAAATTACCACTATATTCAATGTTCAAGTTGAAACGCCGAACATTTTACCAGGAATCTCAGAACAGCAAATTAATGCCAATCTCCGTATGAAACTTTCTAAAGAATTTCAAGGTGTAAGCAAAAGTCTTCAGTCTAGAATAATAGAAACTATTCAAAAGATAGCCTCAACAAAGAAATCGAATCAATCAAGACTGGCTTCGAAAAGACCATATAATCTCAAAGTCAAAAAGACTATAATTAAAAGGAAGAGACTTCGCTCCAAGTTTGGTTGGTATTGCCGACAATGTGACCTTAAATTTGATTCGGGGGAAGAATTGGAAACACACAAGAGTTCAAACACTTGCTCCACACACCCTTGTCAGTACTGTGGAAAATTGTTCAACTCGAAGAAAATATTGCTGGAACATGAGCGCCTGCACACCAATGAGCGGCCTTACATGTGTGAATATTGTGGGAAGAATTTCCGCACATGTACATTGTTGCGCACCCATCATAATTCTCACGCCACGAACCAAACCTTTGTGTGTCCGGACTGTGGCAAGAGCTATAACAACAAGGCAAGCTTCCACTACCATGCTGCGACCCACAAAACCCAAGAGTTTCTTTGTGACATCTGTGGGAAGAAGCTAAAACATGCTGGAAGTCTCCGCATCCACAAGCTTAAGCACAGCAACCCAGACGCCTTCAAGCGTGTCTCGTGTGACATATGTGGCAACTTATATGAGAGCAGgTACCGAATGATGGAACATCGGCGTTTGCACACTAACGAACGTCCATACAAATGCACCGAGCCagattgtttcaaaatgttccGTAAGCTGGAGCAACTTCGACAGCACTCAACTGTTCACACAAACCTACGCAAGTTTAAGTGTGATGTATGTGATAAGTCCTTTAAGCGGCGCAGCAATTTGAAGACCCACCGCAAGATCCACTGCCAGGACTACCGCTATAAGTGCAGTGTGTGCTTGCTACCATACAACAGTCTGCGTGAGCTGCTGTCTCATCGCTCTTTACATACCCAAGAGGAACTCAAGCAAGCCAACAAAGAGCCATTCGAATGCCCCGAGTGCAAAAAGATCATGTCGACTAAAGTGTCTTTGCAACAGCATCTGTTAACTCATACCAACTTGGCGCCATTTGGTTGTAATTTTTGCCAGCGGTCGTTTAGGAGCAAAATGTCACGTGACGTCCACCTGCGCACACATACCGGAGAAAAGCCTTTTGCTTGCAAATATTGCGAGGCAAATTTCTCGCTGAATGCGAGTCTTGTGGTTCATGAGCGCATTCACACTGGCGAGAAACCTTTCCCTTGCAATATGTGCGACAAGGCTTTTCGTTCAAAGATCAACCTTATGCAACACTCTATTGTACACTCAGAACTTCGCCCGTATGTTTGCAGTGTTTGTAACCGGGCGTTTCGCAGGCGAGACGGCCTTGAAACACACATGCGTGTTCATACTAACGAGCGACCATATGCTTGTAAATGGTGTGATCGTGCATTCAAGCAAAAGGGTGACTGTAACAAACATatgaacacacattttaaaactactgCGGTGCCAGTGGCTGAAGATACGACGACGTCGTCTGCATATACTTGCCCGTTTtgtatggGGCTTGATTCATACATAGGTAGAATAGTGCAGGCAAAGAAAGCTTTTCATGACGTCATTATTAACCTCAACTAG
- Protein Sequence
- MAATLDLNKLGVVAGQLCRVCARLSRRLTPIFGQKGIEIDLATKIHTHLPIMVTEDDLMPVCLCEPCIHKLQVCHNLVNTCLEGDIRLRKIMGLPIEQEVTPEPDCELIDLEKEEDLEKEEPSEEAATPEDKNQETEHKQLQEESDDDFLWEEDQSAVDVNPPPPPPDEIRPQRVVKRGRPRKYPVPQEIKQVCNPPLVFYESKHAFDLHMLNHLEAEEGEIRTCMSEDANIVELTNEHIDQSNTSSKKHQASETQNRFTRTDLEPAPNDVFSYLCSYCKETLIGTDMFLAHQSQMHPDKVFTCTICKPHVVFYETKELFERHMLCHPQEIIERDDSLEESVITDLDKPATEDYAETLPTGTTDENVSVSIPDDASDLITASNEVAGSSACPVDVSTLVKDDSENNFSFVDASIPYQENPVDTFTFADAEIPAIKSNVTDVTTSDPSPKQPDNLEITTIFNVQVETPNILPGISEQQINANLRMKLSKEFQGVSKSLQSRIIETIQKIASTKKSNQSRLASKRPYNLKVKKTIIKRKRLRSKFGWYCRQCDLKFDSGEELETHKSSNTCSTHPCQYCGKLFNSKKILLEHERLHTNERPYMCEYCGKNFRTCTLLRTHHNSHATNQTFVCPDCGKSYNNKASFHYHAATHKTQEFLCDICGKKLKHAGSLRIHKLKHSNPDAFKRVSCDICGNLYESRYRMMEHRRLHTNERPYKCTEPDCFKMFRKLEQLRQHSTVHTNLRKFKCDVCDKSFKRRSNLKTHRKIHCQDYRYKCSVCLLPYNSLRELLSHRSLHTQEELKQANKEPFECPECKKIMSTKVSLQQHLLTHTNLAPFGCNFCQRSFRSKMSRDVHLRTHTGEKPFACKYCEANFSLNASLVVHERIHTGEKPFPCNMCDKAFRSKINLMQHSIVHSELRPYVCSVCNRAFRRRDGLETHMRVHTNERPYACKWCDRAFKQKGDCNKHMNTHFKTTAVPVAEDTTTSSAYTCPFCMGLDSYIGRIVQAKKAFHDVIINLN*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01447806;
- 90% Identity
- iTF_01448835;
- 80% Identity
- -