Tcom002052.1
Basic Information
- Insect
- Timandra comae
- Gene Symbol
- L
- Assembly
- GCA_958496195.1
- Location
- OY292354.1:7197132-7200758[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.51 46 5.4 5.8 1 23 3 25 3 25 0.97 2 15 4.5e-06 0.00041 21.3 5.1 1 23 31 53 31 53 0.99 3 15 1.4e-05 0.0013 19.7 0.1 1 23 59 81 59 81 0.98 4 15 0.92 83 4.6 0.0 10 23 104 118 103 118 0.93 5 15 2.2 2e+02 3.3 0.2 3 23 140 162 138 162 0.79 6 15 0.24 22 6.4 0.0 3 23 220 240 219 240 0.97 7 15 0.12 10 7.4 0.1 2 23 254 275 253 275 0.91 8 15 0.00018 0.016 16.2 0.9 1 23 283 306 283 306 0.94 9 15 0.038 3.4 8.9 0.2 1 22 311 332 311 334 0.89 10 15 0.00037 0.033 15.2 0.1 1 23 388 412 388 413 0.94 11 15 0.00057 0.051 14.7 0.0 2 23 471 492 470 492 0.96 12 15 0.047 4.2 8.6 0.0 1 23 500 522 500 522 0.98 13 15 0.073 6.6 8.0 0.2 1 23 624 646 624 646 0.96 14 15 0.0028 0.25 12.5 0.1 1 20 654 673 654 676 0.95 15 15 6 5.4e+02 2.0 0.1 6 23 687 704 686 704 0.94
Sequence Information
- Coding Sequence
- ATGCCATTTCGGTGCGAATTCTGTTCGAGGCTGTTCAAGCACAAACGCTCTAGAGATCGTCACGTGAAGCTTCATACTGGAGACCGCAAGTACCGGTGTTCTCATTGCGAGTCTGCCTTTTCCAGGAGCGATCATTTGAAGATCCACATGAAGACACATGACAATCAGAAGCCGTTTCAGTGCACCGTATGTAACCGCGGGTACAATACGGCCGCAGCGCTGACAGCTCACATGCAAGGACACAAACGTGAAAGGGAAGGGCGCGAGCCTGATCGACGACGAACTATACGTTGTTTACGGCGAGGAGATTTTCGTAGACCTGACTTGTTACAGGCTCATCTCACAAGTCCGCATGACATAGAAGCACTGACTCAACCGCGACGCGTGGCCTCTCAGCCTCCTCCGACCCTCCTGGCCTGCATGTACTGCACCCGCGATACCTTCACCAGTATGGAACAGCTTCAGTTGCACGTGCGGGCGGCCCACTCTACTCTCCTCAATGGAGATCCATCACTGCAAAACGTGGATCAACCCGCTCCGACCGATCTCAGCCGACGGGAATCCGACATCAGCCGATCAGATGACGAGCCCCCTGCGAAGCGGTCGCGTTTCGGTTCCGGCACACCTCAGGCTACATTGTCACCCAATACGTTACTCTGTAACCAGTGCGATGCGGCACTGCCGGACTTCGAAGCTTTTCGCGCTCACTTGAAAGGGCATCTAGAAGAAGGCGGAGAACTGAGTCGGACGAGTCCCCAGCCCTGCGTGCACTGCGGAGCGACGTTCGCCGACGCGGCCGCGTCCGAGCGTCACCTGACGGCCCACTACCTGGCCGTCTCCTGCGAGTACACCTGCCACAGCTGCGCCAGGAGTTTCGCTTCCCGGGACGACCTGCAAAGCCATCTTCTGGACCTCCACGCCCAGCACCTCTACCGGTGCTCGTTCTGCAAAGAAATATTCGACTCCAAGGCGGCCATTCAGGTCCATTTCGACTTGGCCCACGCCGGCGAGAGCAAGGTGTGGTTGTGCCGCGGGTGTGgtggcgcggcgggcgcgctgCGCTCGGAGGCGGAGGGCGCGGCGCACGTCCGCGCGCGGCACGCGGGCGCGCGCTGCGCGTGCGGCGCGCTGCTCGCAGCCGCGCGCGCCCGGCCCCGCGCCTTCCGCTGCCCCGTGCCCGCCTGCACCGAGGCCTTCGCCGTGCAGTATCTCTTGGAGCGCCATATGCAAGTTCATCACGCTCTTTCGCATCAGGTGATGAACGGTGACTCGACGAGACCGAAACGCGTAGAGAACAACAACGGCACGGAGGGCGAGGGCGCGTGCTCCCCCTGCCCGCCAAGTGGCGAAGCGGGCGCGGTCGGCGCCGGCGCGGACGAGCGGCGGCGCAAGAACGGCGCGGTGGCGCTGCAGTGCGCGTACTGCGGCGAGCGCGCGCGCACGCGGGCCGAGCTGGAGGCGCACACGCGCGCGCACTCGGGGCCCGCCGCCGCGCGACACAAGTGTCTCATCTGCGACGAGGTGCTGCCGTCCGCCGCCGTGCTGGCCGAACACAAACTGACGCATTGCAAGGTGGTAGCGGGCGACGTGTGCTCGCGCTGCCGCGCGCGCCTGCTGTCCGAGGAGTCGTTCCTGGGGCACATGGCGCGGCACCACCCCGCGCTGCCGGCGCCCTGCGTCGTGTGCCGACAGACGCTGGCCTCCGAGGCGGAAGCGAGGCTTCACGCTCGGTTCCATCTCAGGCCAAACGAAGACGAACAACGTTGCGCGATTTGCCTGCGCGCGCTGTCGGAGGGCGAGGGCGGGTCGGGCGCGCGCGCGTGCGCGTCGTGCTACGCGCGCCACGTGCGGCCGCGCGCCGGCGCCGAGCACGAGTGCCGCCTGTGTCGGCGCGCGCTCGGCTCGCCCTCGCGCTTGCAGGCGCACCTCATCGAGCACACGTTTGCCGGCATCGGCGCCTTCACGTGCTACCTGTGCTCGGCCGTGTTCACGAGCGCCGCCGGCCTGCAGCGCCACCTGCCCGAGCACGCGGCCGCGCCGCGCCCCTACGACTGCGCCTGCGGGATGAAGTTCTTCTTCCGCGCGGAGCTCGACAACCACGCGTTCGTGCACCTCGAGCACTCGACGCAGCGCGCCTTCTACGAGGCgtgcgcgcgcggcgcggccggTGCGTGGGCCGCGCTCGCGCCGCCcgacgcgccgcgcgccgcctcaccgcccgcgcccgcccacGTCAAGCGCGAGCCCGACATCAAGGAGGAACGGAACGACGAATACATCGAGGTGGCGtctccgccgccgccgcccgtgAGCCCGGTGCCGCCGGCGGCCAGCccggcgccgccgcccgccgcgccgtcGCCCGCGCCGCTCGTCAAGCTGGAGAAGCCCGACGAAGACTGA
- Protein Sequence
- MPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCSHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTAHMQGHKREREGREPDRRRTIRCLRRGDFRRPDLLQAHLTSPHDIEALTQPRRVASQPPPTLLACMYCTRDTFTSMEQLQLHVRAAHSTLLNGDPSLQNVDQPAPTDLSRRESDISRSDDEPPAKRSRFGSGTPQATLSPNTLLCNQCDAALPDFEAFRAHLKGHLEEGGELSRTSPQPCVHCGATFADAAASERHLTAHYLAVSCEYTCHSCARSFASRDDLQSHLLDLHAQHLYRCSFCKEIFDSKAAIQVHFDLAHAGESKVWLCRGCGGAAGALRSEAEGAAHVRARHAGARCACGALLAAARARPRAFRCPVPACTEAFAVQYLLERHMQVHHALSHQVMNGDSTRPKRVENNNGTEGEGACSPCPPSGEAGAVGAGADERRRKNGAVALQCAYCGERARTRAELEAHTRAHSGPAAARHKCLICDEVLPSAAVLAEHKLTHCKVVAGDVCSRCRARLLSEESFLGHMARHHPALPAPCVVCRQTLASEAEARLHARFHLRPNEDEQRCAICLRALSEGEGGSGARACASCYARHVRPRAGAEHECRLCRRALGSPSRLQAHLIEHTFAGIGAFTCYLCSAVFTSAAGLQRHLPEHAAAPRPYDCACGMKFFFRAELDNHAFVHLEHSTQRAFYEACARGAAGAWAALAPPDAPRAASPPAPAHVKREPDIKEERNDEYIEVASPPPPPVSPVPPAASPAPPPAAPSPAPLVKLEKPDED
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00836866; iTF_00837831; iTF_00834917; iTF_00407007; iTF_00407814;
- 90% Identity
- -
- 80% Identity
- -