Tcom017746.1
Basic Information
- Insect
- Timandra comae
- Gene Symbol
- -
- Assembly
- GCA_958496195.1
- Location
- OY292372.1:3040147-3049686[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 3.9e-05 0.0035 18.3 6.9 1 23 187 209 187 209 0.98 2 13 5.5e-06 0.0005 21.0 0.5 3 23 223 243 222 243 0.98 3 13 4.6e-05 0.0041 18.1 2.1 2 23 252 273 252 273 0.98 4 13 0.00029 0.026 15.6 2.1 1 23 279 301 279 301 0.98 5 13 1.4e-05 0.0012 19.7 3.0 1 23 307 329 307 329 0.98 6 13 1.5e-05 0.0014 19.6 8.4 2 23 336 357 335 357 0.97 7 13 1.5e-05 0.0013 19.6 0.7 1 23 363 385 363 385 0.98 8 13 9.7e-06 0.00087 20.2 1.6 1 23 391 413 391 413 0.99 9 13 0.00036 0.032 15.3 1.3 1 23 419 441 419 441 0.98 10 13 0.00011 0.0099 16.9 1.9 1 23 447 469 447 469 0.98 11 13 2.4e-05 0.0022 19.0 0.9 1 23 475 497 475 497 0.98 12 13 2.1e-06 0.00019 22.3 1.3 1 23 503 525 503 525 0.99 13 13 9.2e-05 0.0082 17.1 3.1 1 23 594 616 594 616 0.99
Sequence Information
- Coding Sequence
- ATGGCTGGAACTAGCGTGAATGTGAACAAAATGCGGAATATAAAGATGGATAAAGTATGTAGAGCTTGTCTGGAGATAAAAAGGGATATGAGACCTTTATTCGAGCAACTGATGGCCACTATGTTGATGGGCATTTCGAAAGTGCAGGTGGCAGTGGGCGACGGACTACCATCCCAGCTGTGCCTGCAGTGCGTCCACCAGATATCGCGGTGCCATGCCTTCAGAGAACTCGTGGAGCGAAACGACGCCATACTCCGCGAGCACGCCAACTACTTGGCAGACGAGGCGCTCAAGAAGGACAAAATTCTAGAAATGCAGTACATGGAAGTCCCGTTAGCAAACCCTAACCAAATCCTGGAAGGGTTCTTCGATACTCCAACCGAAATAGAGTCTATTGCTAAACCGGAGGAGAGTACGGAACAGAACTTTGAaaagCCAGCCGCAGAACAACAAATCACATCGAAAGATGACGGCGACGCGGATGCCTTAAATTCTGACGAGGAGAACTACCTTCAAATGGTGGTGTTCCAAGCCACGGCTACCGTATCTCCTGGTAGGCACGTATGCAATCTTTGTCACAAGGAGTTCAAGCACGCCCGATGGCTAAAGCAACACATGAGGTCTCACACCAACTGGATAAAAGCTAACTGCAAGAAGCCACCCATGTGTACTATTTGCGAAAGGACTTTCAAGGGTCCCGGAATGCTGAAATTGCACATGCGTACCCACGAGCAGAGACCACCAAAGCAGCCGACCTGTTCAGTTTGCCAACGCACGTTCCCTACCAAGACGCTCCTATACAGACACAGACAGACTCACTTTGAGCAGAAGACCCATCAGTGCACAGTTTGCGAGAAGAGGTTCTTCAGTGGGTATGCGCTGAGATCTCACATGGCGCGTCATAGAGGCGAAAGACCTTACGTCTGCTCCAATTGCCACAAGAGCTTCTACAACCCCACTGATTTGAAGGTTCATTTCCGTCTGCACACCGGCGAGAAGCCTTTGAAATGCAGCGAATGCAACAAAACGTTCCGTCGCCACTCCACGCTGTGCCAGCATATGAAGAAGCATCGCGGCATCAGGAATCACGTGTGCAATGTCTGCAATAAAGGATTCTATGAAGTTTCTAAATTGAATGCGCATATGAGAGTGCATACAGGTGAACGTCCCTACGAGTGCCAGTTCTGTTCCCGTCGTTTCGCGCAACAATCTGCGTTGATCTACCACCGACGGACGCACACGGGCGAGAAGCCTTACTCTTGCAAACTGTGCACGGCCAAGTTCACAACCTCATCGGCCAGGAACAACCATATGGTCACACATACTGGGAATAAGAgGTTCGTCTGTCCAGTATGTTTCAAAGGCTGCACCTCCCGCAGTGAGTTGCGAGTCCACACCAGTAAGCACACGGGCGAGAAACTGTTTGAATGCGAGACGTGTTCTCAGAGGTTCAGTTCGGCGTCGTACCTCGCAGTGCATCGCCGGTACCACACGGGCGAGAGGAAATACCAGTGCAACGTTTGTGGGAAAGGTTACATAGAATCAAATTCTTTTAAGAAACACATGAAGACTCACGAATCTAAGTCAGATGACAGCTCAGAGACCAATCAGGAACAAGCGCATAAAAATGATTCACATACAGATGACACACAGGACGCAGTTAATGAAGATCATAATGACCAAGGGCAAGCGGAAGAGATGTCAGTCCAATCCCAAGGCCAGTCTCACCAAGTCCAAGAGCAGTCTCCGTCGCCGGCCGAAGCGCCCCAACAGAAACGCTACAAGTGCGGCATTTGCGTCAAAACGTACATGTACCTACATAGCCTCAAGAAGCATATGTTGACACATATTCcccaacaacaacaacaacaacaacagcaGCAACAGCAAATGCAGCAACATCAacaacagcagcagcagcagcagcaacaacaacaacaacagcaAGCAGTCCAACAGACAGTGCAGGTCACGCAGTCGGCTCAACAGCACATTCAGCAACAGCAATTACAGCAGTTGCAACAACAACAGCTGCAACAGCAAGTGCTGCAAGTCGGCAGCGTGCAGCAGTTGACGGTACCGATACACGCACAGCAATTGCCGCAGAGTATCACTGTTAATGGTGTACAGCCGGGCCAGCACACGTACCCGGTGATATCGTCGGTGCAGTCTCTCCAGCTCCAACAAACACAACAGGTTAACACGCAGCCGCAACAACTGCACGTTCAAACGATACAGATACATCCGCAGCAACAACATCAGCCGATACAAATTCATgcGGTTGGAGTCCAACAAGTTCAACAACAGCAGTTGCACGTCGCTACGTCTAGTTGTCAGACAATGTTACCCAATATTTTGCAGCTTCAACCAGCGACGGTGGTGTCCGGTCTAAGCCAACAAGACTTGAGCGGCGTCGCTCATCGCATTATATTGCAACCGCAAACCGCTACACCACACCCCGCTGTATATACCATACATCATTGA
- Protein Sequence
- MAGTSVNVNKMRNIKMDKVCRACLEIKRDMRPLFEQLMATMLMGISKVQVAVGDGLPSQLCLQCVHQISRCHAFRELVERNDAILREHANYLADEALKKDKILEMQYMEVPLANPNQILEGFFDTPTEIESIAKPEESTEQNFEKPAAEQQITSKDDGDADALNSDEENYLQMVVFQATATVSPGRHVCNLCHKEFKHARWLKQHMRSHTNWIKANCKKPPMCTICERTFKGPGMLKLHMRTHEQRPPKQPTCSVCQRTFPTKTLLYRHRQTHFEQKTHQCTVCEKRFFSGYALRSHMARHRGERPYVCSNCHKSFYNPTDLKVHFRLHTGEKPLKCSECNKTFRRHSTLCQHMKKHRGIRNHVCNVCNKGFYEVSKLNAHMRVHTGERPYECQFCSRRFAQQSALIYHRRTHTGEKPYSCKLCTAKFTTSSARNNHMVTHTGNKRFVCPVCFKGCTSRSELRVHTSKHTGEKLFECETCSQRFSSASYLAVHRRYHTGERKYQCNVCGKGYIESNSFKKHMKTHESKSDDSSETNQEQAHKNDSHTDDTQDAVNEDHNDQGQAEEMSVQSQGQSHQVQEQSPSPAEAPQQKRYKCGICVKTYMYLHSLKKHMLTHIPQQQQQQQQQQQQMQQHQQQQQQQQQQQQQQQAVQQTVQVTQSAQQHIQQQQLQQLQQQQLQQQVLQVGSVQQLTVPIHAQQLPQSITVNGVQPGQHTYPVISSVQSLQLQQTQQVNTQPQQLHVQTIQIHPQQQHQPIQIHAVGVQQVQQQQLHVATSSCQTMLPNILQLQPATVVSGLSQQDLSGVAHRIILQPQTATPHPAVYTIHH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00406942;
- 90% Identity
- -
- 80% Identity
- -