Tcom003921.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Timandra comae
Gene Symbol
Hr39
Assembly
GCA_958496195.1
Location
OY292356.1:2694838-2709325[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 3 2.8e+04 -6.2 6.4 116 160 260 304 131 338 0.62
2 3 4.5e-08 0.00042 20.5 0.1 1 20 435 454 435 462 0.91
3 3 8.6e-66 8e-62 210.6 0.0 148 408 484 753 464 753 0.84

Sequence Information

Coding Sequence
ATGTCGAGCGAAGGAGAGCCTGTCAAAGTGGAGGGGGGACACGTGTCAGTCACAACGATCAGCATGTCAGGGCCGGAGACCAGTAATGGTCAGTTCTCGTACAGTTCGAGCGGGATCCGCATCAGCGTTTCTTCGGAGCCCCACGACGAGGACTCCACTGACGCTGAGATCTCTAAAATTGATTTCACCCAAcatcagtatgagGTGAACATGCGTAACAAAAAGAAGCGTTCCCTGAGCGGGGCTCAGTACGAGAACCCGAACGATCGCGAGAGGCCGATGTCGTGGGAAGGGGAGCTCTCCGACTCGGAAATGGTCATCGATACCAGCATTAATAACGATGAAAACAGCAACTCATTAGACCTGCAATCGTCCCGGGATTCCATAGACACGCTCCGCAATGTGACCATAAAGACGGAACCGATGAAGAATGACTCGCTACAGACCATGGATGACCAGAGGGTACTGGACTTGAAGTACTCAGTGCCTTTACAGCAACACCAACGAAGTCTTAGTATGAATAGGATACCTCTCCTCTCCGACAACATTCCTCTATCCCTGCCCCGTCGCCCGTCGTCCCCGACCAGCAGTGCGAAGTCGCTCGCTCTCTCAGACCACGGGACGATGCCGCTGCAGACCTCTTTGGGAGAAGTGCAGAACTTGACTATCAAGAAGGAGACGATGGCTGAGCTAAAATGCGAGCCGTCCGGCCTAGACAAGTTGATAGGCCAGCACGGGTCTCCATTACTGGGGCGCCTGGCGCGCGTCCAGTCCAGTGCCAGCACTGACTCCGCAGTACATTCCATGTATACACACAGTGTGTACAGCAGCCCGTCGGCCAGTCCGCGCGGGTCGCGTCACTTCACGCCCTCTCTCTCTAGAAACAACAGCGACGCGTCACACTCCTCATGCTACTCGTATAGCTCCGAGTTCTCACCTACACATTCGCCTGTtcagGGTCGTCACCCCCACGTCCTGTACCGCGAGGCGCCGGCGGTGTACCCCGCGTCGCCCGCGCACGACGACGACGCGGACACTGACGACCGCCTGCATCACCACCAGGGGATCAGCCGGCAGCAGCTGATTAATAGCCCCTGTCCAATCTGCGGCGACAAAATCAGCGGGTTCCATTACGGTATATTCTCATGCGAGTCTTGTAAGGGATTCTTCAAGAGGACCGTCCAGAACCGCAAGAACTACATGTGTTTGAGAGGCGGCAACTGTCCTGTCACTGTCGCTACGAGGAAGAAGTGTCCGGCTTGTAGGTTTGACAAGTGCTTGGGATGTGGGATGAAGTTGGAAGCAATAAGAGAAGACCGAACTCGAGGTGGCAGGTCCACGTACCAATGTTCGTACACGCTCTCCGGCGCCGCGTCCACTGGCTCGCTACTGTCCGCGCATGTACCGACCACATTACGGCATGCTTCCAGTCTTACTAGTGTTAACGGTCCAGGATCATACAACAGTAGAGGGGAGTCGAGTAACAGTCGGTTAACGCCCGACATACCTCCATTattacaaGAAATAATGGACGTAGAACACCTCTGGCAGTACAACGAATCCGAACTTAATCGCCTCGGTAAGAGCCCGGGGAGTCCTTCAGCCAACCCTCTGCTGGCCGCGAGCGGGATCACGGCGCAGAACTCGAGTCCCGACTTCCTGGCCGACCTGTGTAATATAGCCGACCACAGGCTGTACAAGATAGTGAAATGGTGCAAGAGCTTGCCCTTGTTCAAGAATATTTCGATAGACGACCAGATCTGCCTGCTGATAAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGGGTGAGCACGCCGGGCGAGGTGCGCGTCGGCGGCGGCCGCGGGATCACGCTGCATCAGAGTGCCAAGTTGGGTCTAACGCCGTGTATAGAGAGGATGCTGAGCTTCACCGACCACTTGAGGAGGTTGCGGGTCGACCGGTACGAGTACGTCGCGTTAAAAGTCATCGTACTGCTCACTTCAGACGCTCCCGAGCTTCGTGAAGCTGAGAAAGTACGTGCGTCCCAAGAGAAAGCCCTAGCGGCACTACAGGCTTACATCGCGACGCACTCCCCGCAGACACCCGCCAAGTTTGGAGAGCTTTTACTACGCATTCCCGAATTACAGCGGACTTGTCAgTTCTTCATGCAAGTCGGCAAAGAGATGCTGAACCCAGCGAATAAGAATAAAGATGGCGAGGCGCCGAGCTTCAATCTTCTCATGGAACTTTTGAGAGGAGACCATTGA
Protein Sequence
MSSEGEPVKVEGGHVSVTTISMSGPETSNGQFSYSSSGIRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRNKKKRSLSGAQYENPNDRERPMSWEGELSDSEMVIDTSINNDENSNSLDLQSSRDSIDTLRNVTIKTEPMKNDSLQTMDDQRVLDLKYSVPLQQHQRSLSMNRIPLLSDNIPLSLPRRPSSPTSSAKSLALSDHGTMPLQTSLGEVQNLTIKKETMAELKCEPSGLDKLIGQHGSPLLGRLARVQSSASTDSAVHSMYTHSVYSSPSASPRGSRHFTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVLYREAPAVYPASPAHDDDADTDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHVPTTLRHASSLTSVNGPGSYNSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELNRLGKSPGSPSANPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYIATHSPQTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKNKDGEAPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00033911;
90% Identity
iTF_00806824;
80% Identity
iTF_01444003;