Basic Information

Insect: Tillus elongatus
Gene Symbol: Hr39
Assembly: GCA_964006375.1
Location: OZ023262.1:214009128-214057690[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 4.2e-09 0.00041 22.3 0.0 1 28 192 219 192 254 0.76

2 3 0.026 2.5e+03 -0.1 0.0 81 121 244 281 219 307 0.75

3 3 2.4e-74 2.3e-69 237.2 0.2 205 408 320 518 297 518 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	4.2e-09	0.00041	22.3	0.0	1	28	192	219	192	254	0.76
2	3	0.026	2.5e+03	-0.1	0.0	81	121	244	281	219	307	0.75
3	3	2.4e-74	2.3e-69	237.2	0.2	205	408	320	518	297	518	0.96

Sequence Information

Coding Sequence: ATGATGCGCTTGGTACCGGAAAATATTGGTTTAACTGCAATTATAAGGGACCAGTACATTGAAAGGCATACTACTGAATTTGTCAATGAGCTCTATAATCCTGATATAGCTAATCCGATTACAATTATCTGTATTGCGGCCCCTACAGCTATATTCCGAAAGGGTCGCCATATGCACAGTATTCATAGTAGTCCCCTACATCACAATGTATTATATCGTAGTCTGCAGGAAGATCTACCAAGTGCAAACTTCCCACCCGAACATGATTGTCTAGATGACAGTGAGGATAAGACTGGCCTAGTTCATCCAACGGCGGCGTTGACCACCCAGCCCGGCATCTCCCGTCAGCAGCTCATCAACAGTCCCTGTCCAATCTGCGGTGATAAGATATCTGGCTTCCATTACGGCATATTTAGTTGTGAAAGCTGTAAGGGCTTTTTTAAGAGGACAGTACAGAATAGAAAGAACTATGTGTGTTTGCGTGGAGCGGCCTGTCCTGTTACGGTTACAACTAGGAAAAAGTGTCCTGCGTGTAGGTTTGATAAGTGTCTGCAGTGCGGAATGAAGCTAGAAGCTATTAGAGAAGATAGAACTAGAGGCGGCCGTTCAACTTATCAGTGTTCATATTCTCTACCTCCATCACTAACAAACCATGCAGAATTACGGGCTAGTTCAACTGATCTTCGAGGACTGGGTGAATCTCATTTGACTGTCAAATTAGAACCACCTGATTCATCAACACCACATCATAAGAGAGGATCGTTGCCCGGATTCAAAGGTGTCCCATCATTattgcaagagATAATGGATGTGGAGCACCTGTGGCATTATAATGAAAGCGAGCTGCACAAACTGAACACTGAAGGGCATCTGGGTAAAGAAGGATCAAGCGGGGCCGTCCATAACTTATCGAGTCATCCACTGTTAGCAGGAACAGCCTTAGCTGGTTCGACAGACACTAATCCTGATTTTGTTGCAAACTTGTGCAATATTGCTGATCATAGACTGTATAAAATTGTTAAATGGTGCAAGAGTTTGCCTCTCTTTAAGAATATTTCTattgaTGACCAAATTTGTTTGCTTATCAATTCTTGGTGTGAACTGTTGTTGTTTTCTTGTTGTTTTCGTTCGATGAGTACACCTGGAGAAATAAGAGTTTCACTAGGTAAAAGCATTACACTTAGTCAGGCGAGAGATATGGGCATGCAGGCATGCATTGAACGTATGTTGAATTTTACTGAACAGTTGCGAAGACTTAGGGTTGACCAGTATGAATATGTTGCTATGAAGGTTATTGTTTTACTTacatcagACACATCTGAGTTGAAAGAAGCCGAAAAAGTGAGATTATCACAAGAAAAGGCACTCAAAGCTTTACAAGACTACACTTTGACTCATTATCCAGAGAGTCCTGCCAAATTTGGAGAACTGTTACTACGAATTCCAGAACTACAACGAACTTGTCAGGTGGGAAAAGAGATGTTGACAACTAAATCGAAAGACGGAGAAGGACCAAGCTTTAATCTATTGATGGAGTTGCTCAGAGGGGACCATTAG
Protein Sequence: MMRLVPENIGLTAIIRDQYIERHTTEFVNELYNPDIANPITIICIAAPTAIFRKGRHMHSIHSSPLHHNVLYRSLQEDLPSANFPPEHDCLDDSEDKTGLVHPTAALTTQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAACPVTVTTRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLTNHAELRASSTDLRGLGESHLTVKLEPPDSSTPHHKRGSLPGFKGVPSLLQEIMDVEHLWHYNESELHKLNTEGHLGKEGSSGAVHNLSSHPLLAGTALAGSTDTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLSQARDMGMQACIERMLNFTEQLRRLRVDQYEYVAMKVIVLLTSDTSELKEAEKVRLSQEKALKALQDYTLTHYPESPAKFGELLLRIPELQRTCQVGKEMLTTKSKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01296227;
90% Identity: iTF_01442840;
80% Identity: iTF_01442840;