Basic Information

Insect: Tiliacea citrago
Gene Symbol: -
Assembly: GCA_963921375.1
Location: OY992790.1:27899661-27900950[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.052 3.8e+02 2.2 0.0 32 50 63 81 58 93 0.86

2 9 0.052 3.8e+02 2.2 0.0 32 50 106 124 101 136 0.86

3 9 0.047 3.4e+02 2.4 0.0 32 50 149 167 144 181 0.85

4 9 0.051 3.7e+02 2.3 0.0 32 50 192 210 186 222 0.86

5 9 0.052 3.8e+02 2.2 0.0 32 50 235 253 230 265 0.86

6 9 0.052 3.8e+02 2.2 0.0 32 50 278 296 273 308 0.86

7 9 0.052 3.8e+02 2.2 0.0 32 50 321 339 316 351 0.86

8 9 0.052 3.8e+02 2.3 0.0 32 50 364 382 359 395 0.86

9 9 0.092 6.7e+02 1.5 0.0 32 47 407 422 402 428 0.87

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.052	3.8e+02	2.2	32	50	63	81	58	93	0.86
2	9	0.052	3.8e+02	2.2	32	50	106	124	101	136	0.86
3	9	0.047	3.4e+02	2.4	32	50	149	167	144	181	0.85
4	9	0.051	3.7e+02	2.3	32	50	192	210	186	222	0.86
5	9	0.052	3.8e+02	2.2	32	50	235	253	230	265	0.86
6	9	0.052	3.8e+02	2.2	32	50	278	296	273	308	0.86
7	9	0.052	3.8e+02	2.2	32	50	321	339	316	351	0.86
8	9	0.052	3.8e+02	2.3	32	50	364	382	359	395	0.86
9	9	0.092	6.7e+02	1.5	32	47	407	422	402	428	0.87

Sequence Information

Coding Sequence: ATGAACGTGATTGATTCAAGCCATCTGACCGTCTCGGGGCCTCCTAATAATGAGATGCAACCTACGTCGTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACTGCCATGTCGCGACACGGTGTACTACGTCCGTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACTGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACTGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCAACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACTGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACTGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACTACGTCCCTATGGGCCACACGGCCATGTCGCGACACGGTGTACCTAACAGTATAGAATAG
Protein Sequence: MNVIDSSHLTVSGPPNNEMQPTSYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHCHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVLRPYGPHGHVATRCTTSLWATRPCRDTVYYVPMGHTAMSRHGVPNSIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -