Basic Information

Insect: Thumatha senex
Gene Symbol: Hr39
Assembly: GCA_948477245.1
Location: OX419726.1:7215862-7237461[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 1.7 2e+04 -4.4 7.8 66 163 214 311 164 328 0.53

2 3 4.8e-08 0.00057 20.4 0.1 1 20 442 461 442 467 0.91

3 3 6.8e-64 8.1e-60 204.3 0.0 153 408 495 760 474 760 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	1.7	2e+04	-4.4	7.8	66	163	214	311	164	328	0.53
2	3	4.8e-08	0.00057	20.4	0.1	1	20	442	461	442	467	0.91
3	3	6.8e-64	8.1e-60	204.3	0.0	153	408	495	760	474	760	0.86

Sequence Information

Coding Sequence: ATGAGTAGCGCAATGACCAGTGAAGGTGACGCGGTTAAGGTGGAGGGGGGACACGTATCTGTCACCACTATCAGCATGTCAGGATCCGAGACAAGTAACGGTCAGTTCTCCTATAGCTCCAGCGGAGTCCGCATCAGTGTTTCTTCCGAGCCCCATGATGAAGACTCCACTGATGCCGAGATCTCCAAAATCGACTTTTCACAACATCAGTACGAGGTTAACATGCGCAACAAGAAGAAGCGATCATCGAGCGGCACGCATTCCGAAGTATCGAATAATGAACGCGAGCGGCCCATGTCATGGGAGGGCGAGTTGTCAGACTCTGAAATGGTCATAGACACCAGTGTTAATAACGATGAAAACAGCAACTCCTTAGATCTTCAATCATCACGAGATTCCATCGACACGCTTCGAAATGTGACCATCAAGGCCGAGCCGATGAAGAACGAGAGCTTTCAAGCAGTGGACGACCGAGTACTGGATTTGAAGTACAGTGTACCGCTACAACCACATCAAAGGAGTCTAAGCATGAACAGGATATCCGTTCTAACTGACGCTACATCGTTGTCCCTATCAAGACGGCCACCATCACCCACGAGCAGTGCCAAATCTTTAGCGTTGAGTGACCAAGGTTCAGCTTCGATGGCGCATTCAGCTTTAGACCAAGTTCATAATCTGATTGTCAAGAAGGAAAGTCAACTTTCTGAACTAAAAAGCGAGCATACAGTTGGAATGGACAAACTGATTGGGGCGTTACATGGATCGCCATTATTGGGCCGGTTACCCCGCGTCCAGTCTAGCGCCAGTACGGACTCAGCTGTCCACTCGATGTACACTCATAGTGTGTACAGTAGTCCGTCCGCCAGTCCGCGAGCTTCGCGCCACTACACGCCGTCTCTCTCTCGCAACAACAGTGATGCATCTCATTCTTCCTGTTACTCCTATAGTTCCGAGTTCTCGCCAACACATTCCCCAGTACAGAGTCGTCACCCTGGACTGCTTTATCGTGAAGCGCCGGCCGCTTACGATACAACACATGATGACGAACCTGATGCACCTGACGACAGGCTACACCATCACCAAGGCATAAGTCGGCAACAACTAATAAATAGTCCGTGTCCAATCTGTGGCGACAAGATCAGCGGCTTCCACTACGGTATATTCTCTTGCGAATCCTGCAAAGGGTTCTTCAAACGTACAGTGCAGAACCGAAAGAACTACATGTGTTTAAGAGGCGGGAACTGCCCGGTCACAGTCACTACCAGGAAGAAATGTCCGGCGTGTCGGTTCGACAAATGTCTTGGGTGTGGGATGAAGCTTGAAGCAATTCGAGAAGATAGAACACGTGGCGGTCGTTCTACGTACCAGTGTTCGTACACGCTGTCCGGCGCCGCGTCCACGGGTTCCTTACTGTCGGCTCACGCGCCTACTACCCTGCGGCACGCCTCTAGTCTCACTTGTGTAAATGGTCCAGCGTCATACAGCCGAGGAGAGTCCAGTAACAGCCAAGTAACGCCCGATATACCACCATTATTACAGGAAATAATGGACGTGGAACATCTATGGCAATACAACGAATCGGAGCTCAGTCGGCTGGGCAAATCGACTTCGGGCAGTCCCTCTGCCAACCCTCTGTTGGCCGCCAGCGGCATCACTGCACACAACTCCAGTCCGGACTTCCTGGCCGATCTGTGCAATATAGCTGACCATAGGTTATATAAGATCGTCAAATGGTGCAAGAGCTTACCGCTGTTTAAGAATATATCTATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGCGTGGGCACGCCGGGTGAAGTGCGCGTGGGCGGCGGCCGCGGCCTCACGCTGCACCAGAGCGCCAAGTTGGGTCTGACACCGTGCATAGAGCGCATGCTAAGTTTTACAGACCATCTGAGGAGGTTGAGAGTCGACAGATACGAATACGTTGCGCTTAAAGTCATCGTTCTTCTCACTTCAGACGCACCGGATCTGCGCGAAGTGGAGAAAGTACGGGCATCTCAGGAGAAGGCGCTAGCGGCGCTTCAGGCGTACATCGCGACACACTCGCCCGCCACCCCCGCCAAGTTCGGAGAGCTGCTGTTGCGCATACCTGAACTGCAGAGGACTTGCCAGTTTTTCATGCAAGTCGGTAAAGAAATGCTGAATCCGGCCAACAAAAGTAAAGATGGTGATGGACCAAGCTTCAATTTGCTCATGGAGCTTCTCCGTGGTGACCACTGA
Protein Sequence: MSSAMTSEGDAVKVEGGHVSVTTISMSGSETSNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFSQHQYEVNMRNKKKRSSSGTHSEVSNNERERPMSWEGELSDSEMVIDTSVNNDENSNSLDLQSSRDSIDTLRNVTIKAEPMKNESFQAVDDRVLDLKYSVPLQPHQRSLSMNRISVLTDATSLSLSRRPPSPTSSAKSLALSDQGSASMAHSALDQVHNLIVKKESQLSELKSEHTVGMDKLIGALHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPGLLYREAPAAYDTTHDDEPDAPDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVTTRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPTTLRHASSLTCVNGPASYSRGESSNSQVTPDIPPLLQEIMDVEHLWQYNESELSRLGKSTSGSPSANPLLAASGITAHNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGTPGEVRVGGGRGLTLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLREVEKVRASQEKALAALQAYIATHSPATPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042698;
90% Identity: iTF_01076559;
80% Identity: iTF_01436212;