Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 4.2 7.7e+02 -0.0 0.0 15 45 94 124 90 131 0.77

2 9 0.51 93 2.9 0.0 21 46 128 153 123 160 0.86

3 9 5.3 9.8e+02 -0.3 0.0 21 46 156 181 148 187 0.78

4 9 0.058 11 5.9 0.0 21 47 184 210 171 216 0.86

5 9 1.5 2.8e+02 1.4 0.0 22 46 213 237 208 243 0.83

6 9 0.1 19 5.1 0.0 21 46 240 265 229 271 0.85

7 9 0.079 14 5.5 0.1 21 45 268 292 264 296 0.90

8 9 0.045 8.3 6.3 0.0 21 45 296 320 292 327 0.86

9 9 0.16 30 4.5 0.0 23 45 326 348 322 351 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	4.2	7.7e+02	-0.0	0.0	15	45	94	124	90	131	0.77
2	9	0.51	93	2.9	0.0	21	46	128	153	123	160	0.86
3	9	5.3	9.8e+02	-0.3	0.0	21	46	156	181	148	187	0.78
4	9	0.058	11	5.9	0.0	21	47	184	210	171	216	0.86
5	9	1.5	2.8e+02	1.4	0.0	22	46	213	237	208	243	0.83
6	9	0.1	19	5.1	0.0	21	46	240	265	229	271	0.85
7	9	0.079	14	5.5	0.1	21	45	268	292	264	296	0.90
8	9	0.045	8.3	6.3	0.0	21	45	296	320	292	327	0.86
9	9	0.16	30	4.5	0.0	23	45	326	348	322	351	0.90

Coding Sequence: ATGTCAGTGCGTTCTCGCACTGGAGCAGCCTTAGATTCGTACACTAGTTGGTGGCGCACTTGGGGCCGTGAAACGCAGCCGCAGTGTTCCCAGCGGTCCCTCGTCGGCTTGCCCGAGGCGGATTACCCGAAGGATTCAGAGAACGAGTCGGTGCGCATCATCCCTTCCTGCACTTTGAGTTCTTCACCAGCTCCAAAGGCCCTCCCTGCCAGGCGCATCATGCCCCTCGAGAGCTCACtgtgcggcgaggtggcggcatcgtcagcggcgccgcgtgttCCACGTGGCAAGCGTGGAGGGCAGCAGGCACTCCACTGTGCAGTCTGCGAGAAGGAGTTCCGATTCAAGAGTGTCCTCCAGGTGCACTTTCGagtccacaccggggagaagcctttcgagtgcacgtTCTGCGGGAAGAAGTTTTCTCATAGTGGAAATCTCAAGTCGCACGTTCGGAcccacactggggagaagcctttcgagagCACAGTTTGCCAGGAGAAGTTCACAGGAAGTGGAATCCTCAGGCAGCATCTTCGGACTCACACCGGAGAGAaacctttcgagtgcacagtttgtaAAAAGAGTTTTACTGCAAGTTGGAGTCTGAGAGACCACCTTCGAACGCACACCGGGGACaagcctttcgagtgtgcAGTTTGCACGAAGAAGTTTACTGCAGGTGGGGTTCTGAGAAAGCACCTTAGAACGCACACAGgtgagaagcctttcgagtgcgcaGTTTGCAAGAAACGTTTTACTGAAGGTGGGGATCTGAGAAAGCACCTTAGAACGCACACAGgtgagaagcctttcgagtgcacagaaTGTCAGCGGAGCTTTACTAGCAGTGGAAATCTCAGAACGCAccttcgcacccacaccggggaaaagcctttcgagtgcacagtttgcaagaaGAGTTTCAATCGAAGTGGAGCTCTCAGAACGCACCTCCTGACTCACACTGGGCACAAGCCTTTCAAGTGCACGGTTTGCAAGAAAAACTTCGCTCTAAGTGGAAATCTCAAGAAGCACCTTCGGACCCACGTCATCGGATAG
Protein Sequence: MSVRSRTGAALDSYTSWWRTWGRETQPQCSQRSLVGLPEADYPKDSENESVRIIPSCTLSSSPAPKALPARRIMPLESSLCGEVAASSAAPRVPRGKRGGQQALHCAVCEKEFRFKSVLQVHFRVHTGEKPFECTFCGKKFSHSGNLKSHVRTHTGEKPFESTVCQEKFTGSGILRQHLRTHTGEKPFECTVCKKSFTASWSLRDHLRTHTGDKPFECAVCTKKFTAGGVLRKHLRTHTGEKPFECAVCKKRFTEGGDLRKHLRTHTGEKPFECTECQRSFTSSGNLRTHLRTHTGEKPFECTVCKKSFNRSGALRTHLLTHTGHKPFKCTVCKKNFALSGNLKKHLRTHVIG

Sequence clustering based on sequence similarity using MMseqs2