Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 7.8 1.4e+03 -0.9 0.0 26 44 76 94 71 97 0.84

2 10 0.0047 0.85 9.5 0.1 20 46 98 124 89 131 0.82

3 10 2.2 4e+02 0.9 0.0 21 44 127 150 123 157 0.85

4 10 0.092 17 5.3 0.3 22 45 156 179 147 182 0.86

5 10 0.0048 0.88 9.4 0.1 21 46 183 208 179 214 0.86

6 10 3.8e-05 0.007 16.1 0.2 21 46 211 236 207 242 0.86

7 10 0.069 13 5.7 0.0 21 45 239 263 235 267 0.90

8 10 0.022 4.1 7.3 0.1 21 46 267 292 263 298 0.86

9 10 0.055 10 6.0 0.0 21 45 295 319 291 322 0.90

10 10 0.00012 0.022 14.5 0.2 21 44 323 346 319 350 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	7.8	1.4e+03	-0.9	0.0	26	44	76	94	71	97	0.84
2	10	0.0047	0.85	9.5	0.1	20	46	98	124	89	131	0.82
3	10	2.2	4e+02	0.9	0.0	21	44	127	150	123	157	0.85
4	10	0.092	17	5.3	0.3	22	45	156	179	147	182	0.86
5	10	0.0048	0.88	9.4	0.1	21	46	183	208	179	214	0.86
6	10	3.8e-05	0.007	16.1	0.2	21	46	211	236	207	242	0.86
7	10	0.069	13	5.7	0.0	21	45	239	263	235	267	0.90
8	10	0.022	4.1	7.3	0.1	21	46	267	292	263	298	0.86
9	10	0.055	10	6.0	0.0	21	45	295	319	291	322	0.90
10	10	0.00012	0.022	14.5	0.2	21	44	323	346	319	350	0.91

Coding Sequence: ATGGCGTGCATCGGGCAATCTTGCTGGACGTGCGAGAAACTGAACTGCTTGGACCTATCTAAGAGCGTCTTCGTCTTGACGCCAAGTCTGCATTCAAAACCAGATTTGGATCCTGCCTGCCAGTTGCATCCCCTGTGCCAGAAGACTCAACTGCCCAGTGCACTGCAGGTCAAGGGAAGCCACGTCGTTTTGAGCGAATCCTCACCAGGTCCGACCATGGCCAACAAATGCACTGTTTGCGCGAAGGTGTTCCAAAGCTTATCGGCGCTCAAAATGCACCTTCGCTCGCACACTGGGGAGAAACCTTTCAAGTGTACGCTGTGCAGCATGTGCTTCAGTCAGAAGGGCAACCTTCGGAGCCATGTTCGAACCCACACTGGAGAGAAGCCTTTCAAATGTGCGCTGTGCAGCAAGAGCTTCAGTCAGAAGGGCCACCTTCAGAGCCATGTTCGGACCCACACTGGTGAGAAGGCGTTTGAATGCTCCATCTGCAATGTGAAGTTCAGACATGAAACCCACCTTCGGAACCATCTTCGAACCCACACTggtgagaagccttttgaatGCTCTATCTGTAATGCGAAGCTTACCCGTGGAACTTCCCTTCGGAGCCATCTTCGAACCCACACTGGTGAGAAGCCGTTTGAATGCTCCATCTGCAATGTGAAGTTTAGACATGAAGCCAACCTTCGTCGCCATCTTCGAAcccacactggggagaagccttttgaaTGCTCTTTCTGTAATGCGAAGCTTACCCGTGGAACTTCCCTTCGGAGCCATCTTCGAACCCACACTGGAGAGAAGCCGTTGGAATGCTCCGTCTGCAACGTGAAGTTTAGTCATGAAGCCAACCTTCGCAGCCACCTCCGAAcccacactggggagaagccgTTTGAATGCTCCGTCTGCAATGTGAAGTTTGGTCATGGAGCCAACCTTCGCAGCCATCTTCGAACCCACACTggagagaagccttttgagtgcTCTGTCTGCCATGCGAAATTCAGTGTCAGTAGCAACCTTCGTCGGCATGTTCGCAACCACATTGGGGAGGTGGCCTAG
Protein Sequence: MACIGQSCWTCEKLNCLDLSKSVFVLTPSLHSKPDLDPACQLHPLCQKTQLPSALQVKGSHVVLSESSPGPTMANKCTVCAKVFQSLSALKMHLRSHTGEKPFKCTLCSMCFSQKGNLRSHVRTHTGEKPFKCALCSKSFSQKGHLQSHVRTHTGEKAFECSICNVKFRHETHLRNHLRTHTGEKPFECSICNAKLTRGTSLRSHLRTHTGEKPFECSICNVKFRHEANLRRHLRTHTGEKPFECSFCNAKLTRGTSLRSHLRTHTGEKPLECSVCNVKFSHEANLRSHLRTHTGEKPFECSVCNVKFGHGANLRSHLRTHTGEKPFECSVCHAKFSVSSNLRRHVRNHIGEVA

Sequence clustering based on sequence similarity using MMseqs2