Ttri025892.1
Basic Information
- Insect
- Therioaphis trifolii
- Gene Symbol
- topi
- Assembly
- GCA_027580255.1
- Location
- CM050411.1:34912020-34916897[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.015 2.2 10.2 0.3 2 23 334 356 333 356 0.93 2 14 0.13 19 7.2 0.1 2 21 389 408 388 411 0.86 3 14 0.16 24 6.9 0.6 3 23 418 439 417 439 0.95 4 14 2.6e-05 0.0039 18.9 5.3 2 23 442 463 441 463 0.97 5 14 6.3e-05 0.0093 17.7 0.5 1 23 469 491 469 491 0.95 6 14 0.0013 0.19 13.5 3.5 1 23 497 520 497 520 0.97 7 14 0.01 1.5 10.7 1.3 5 23 532 550 529 550 0.96 8 14 7.6e-05 0.011 17.4 3.2 2 23 556 578 555 578 0.97 9 14 0.15 23 7.0 2.3 2 23 594 614 593 614 0.96 10 14 4.1e-06 0.00061 21.4 1.4 1 22 620 641 620 642 0.92 11 14 0.0097 1.4 10.8 2.2 1 23 650 672 650 672 0.99 12 14 0.00046 0.067 15.0 5.4 1 23 678 700 678 700 0.97 13 14 2.1e-06 0.0003 22.3 4.5 1 23 707 729 707 729 0.99 14 14 0.0014 0.21 13.4 10.2 1 23 735 757 735 758 0.95
Sequence Information
- Coding Sequence
- ATGAATCAAGAGTCTCAATCATGTTGTCCAGTTTGCACATTGTACTTACGACCAGGAATATCCCTTCCTGCCCATTTGAATACACATCCAAAAAAACACGTTATAAAAGCTTTGTTGACACTAGCCAGTCAGGCGTCAATTGTTCCCAAATCCCTAGATTTAGAAGAACAAACAGAAGAAATCCTCTCAGATGACAGTAGTTCATCTTCGGTGACATCTCGTCATTCGAATGTCTTTCATATTCAGGATGAAGCGAATAACACTGATAGAAATGACAGAAATAGTCCAAATAATTGTCCGTCGCCAAAAAGCCAAAACAGTATGGCACTTTCGGACCTTAGACAAGATCTTGAAGATAATCTAGAGGACGATATTGATATTGATGATAACAATGTTAATTTTGAAGATGATTATCCTCCAGAATTTGAAGAAGACCAACAAGAAGGTAGTTGTAGTTTTCATGGAGAATCAAATGAATCAACTCAACATCGTGAGCACTCTGAAGAAACTGGGTCGTCCATGACAGAACATTTTAATGATCCATTTCAATCAAATGGCAATTTAATAGAAGATGGAGAATACATGTCACGTTATTTTTATTCTAGTGAAAATGCTCGTATATCACATACTGATCCAGATCCTCAGCTTAATCCTCCTCAATATAGTACTCTTACTACCATGGAACTTCACCCAGAGTATTTATCTTCAAACAATCAAGAACATCAGTTAACATTAGATATCCAAACCGATGAACTTATGCCAGCTCATGGAGAGTTATCTGGTCAAGAGAGTTTAGAACCTCCGGAACCAATACTAGCTTCCATATGGACTATGAAAAGTATTGATGAGTCCCAGCCACATAGTAGCACTGCATGGGATGATGCCGTTCACGAAGTTAGTACTGCTGCTAGAAACTTAATGTCCCTAAAAAACCGAGAAGAGATCCCTAAAGAAGAGATAATAGAAAAAAAAGAATTGAAACCATTGATAGGAAAATTAATTTGTCCATATTGTAAATTAAAATTCAATGATGTGAAGACACGTAAAGCACATATACAGGAAGAGCATAAAAATGAAGAAGGTGTGAAGAAAGGATTAATGTATATAAGACCTATGTCAACTAAAATAGAGGAAGGAGTGGATGACTCTCAGTTTCTAAAAGTAGAATGTAGCATTTGTGGTCAAGGATTTGAAGATTACATGAAAATGACATTGCATTTCATTGATTCTCATAAAGATAAGAATAATTTATGTCAAACATGTAATACGGTTTTTCCTATGGTAACAGAATTTAGAGATCATATACTACACGTCCATCCATTGAAATGTAGTTTCTGTGGAAAAACATTCCATTCTCAATTTAATTTGACTACTCATTTGAAACGTCATCTTCAAATTAAGCCATATCTCTGTGATCAATGCAATAAGTCTTTTGTTAGTCGAGTCAGACTTCAAGATCACATGAATGGTCATCTTAATATAAAACCATACAACTGTACTCGTTGCGATCTCGCTTTTAGGTGTAGAGCTAATTTAAATAGTCATATGCGTAAACAACATCAGTCTACTGGCACTCCTAAAGATTTTTATTGTCACTGTGGAGAGGTATTTACATCTTTGAAAAAACTTGCATGGCACAAGGAAACTCATGAAGTAAAACCTAAACAATGTCAGTGGTGTTCGGAACGTTTTGTACACTCAACATCATTGACTAGACACATACGACGTTCTCATGATCCATCATATTTACCAACAAAAGAACGTGACAATGAAAACATGACCTGTCACATTTGTAACAGTACATTTTTACGTAAATCTTTTGCCACTCATATGCTTATCCACAAGGATTTGAGACCTTATTCGTGCAATATATGTAACCGTTCATTTCGTACAAAATGGAATTTAAGAATGCACCAATGGACTCATATGTCACGAACGCATAAACCTTTTAAATGTACCCAGTGTAAAAGTGCATTTTATCTCAAACATGAATGGGAAGCGCATGTCCGTTCCCACAATGGTGTTCGTCCATTTACATGCAATGAATGTGGCAAACAATTTATCAGGAAAAAACATTGTATGAGACATATGGCAGAACATGAGGAAGGAAATCGTTCATATGAGTGTAAAGAGTGCGGCAAAAAATTTCATCGTAGTTACTATCTGACAGATCACTTAAAAACGCACACCGGCGTGAAGCCTCATACATGTCATATATGTGGTAAAACCACTAGTTCTAAGTCTAATCATAACAAACACGTTCGTACGCACCATGCAAGAGAATCGGTGAATACCGAGGGTTAA
- Protein Sequence
- MNQESQSCCPVCTLYLRPGISLPAHLNTHPKKHVIKALLTLASQASIVPKSLDLEEQTEEILSDDSSSSSVTSRHSNVFHIQDEANNTDRNDRNSPNNCPSPKSQNSMALSDLRQDLEDNLEDDIDIDDNNVNFEDDYPPEFEEDQQEGSCSFHGESNESTQHREHSEETGSSMTEHFNDPFQSNGNLIEDGEYMSRYFYSSENARISHTDPDPQLNPPQYSTLTTMELHPEYLSSNNQEHQLTLDIQTDELMPAHGELSGQESLEPPEPILASIWTMKSIDESQPHSSTAWDDAVHEVSTAARNLMSLKNREEIPKEEIIEKKELKPLIGKLICPYCKLKFNDVKTRKAHIQEEHKNEEGVKKGLMYIRPMSTKIEEGVDDSQFLKVECSICGQGFEDYMKMTLHFIDSHKDKNNLCQTCNTVFPMVTEFRDHILHVHPLKCSFCGKTFHSQFNLTTHLKRHLQIKPYLCDQCNKSFVSRVRLQDHMNGHLNIKPYNCTRCDLAFRCRANLNSHMRKQHQSTGTPKDFYCHCGEVFTSLKKLAWHKETHEVKPKQCQWCSERFVHSTSLTRHIRRSHDPSYLPTKERDNENMTCHICNSTFLRKSFATHMLIHKDLRPYSCNICNRSFRTKWNLRMHQWTHMSRTHKPFKCTQCKSAFYLKHEWEAHVRSHNGVRPFTCNECGKQFIRKKHCMRHMAEHEEGNRSYECKECGKKFHRSYYLTDHLKTHTGVKPHTCHICGKTTSSKSNHNKHVRTHHARESVNTEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01347462;
- 90% Identity
- -
- 80% Identity
- -