Basic Information

Insect
Thereva unica
Gene Symbol
-
Assembly
GCA_949987705.1
Location
OX465282.1:29987752-29989866[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.13 36 7.0 2.5 1 23 36 58 36 58 0.96
2 18 0.0062 1.8 11.2 3.6 1 23 157 179 157 179 0.98
3 18 1.4e-07 3.9e-05 25.8 2.6 1 23 185 207 185 207 0.99
4 18 0.00011 0.03 16.7 2.5 1 23 215 237 215 237 0.96
5 18 2.1e-06 0.0006 22.1 1.5 1 23 243 265 243 265 0.98
6 18 0.0031 0.89 12.1 4.1 1 23 273 296 273 296 0.96
7 18 3.2e-05 0.0091 18.4 0.5 1 23 304 328 304 328 0.91
8 18 0.00047 0.14 14.7 1.7 2 23 335 356 334 356 0.95
9 18 0.00051 0.15 14.6 0.5 3 23 366 387 365 387 0.91
10 18 0.0007 0.2 14.2 1.5 1 23 387 409 387 409 0.98
11 18 0.0074 2.1 10.9 3.6 1 23 415 437 415 437 0.97
12 18 0.00041 0.12 14.9 1.2 1 23 439 461 439 461 0.98
13 18 0.11 33 7.2 2.8 1 23 467 490 467 490 0.93
14 18 0.001 0.29 13.7 0.3 1 23 531 554 531 554 0.93
15 18 0.00013 0.038 16.4 3.9 1 23 562 585 562 585 0.96
16 18 0.0032 0.92 12.1 4.6 1 23 593 615 593 615 0.96
17 18 0.00027 0.078 15.4 0.5 1 23 621 644 621 644 0.92
18 18 9.4e-06 0.0027 20.0 3.0 1 23 652 674 652 674 0.98

Sequence Information

Coding Sequence
ATGGATTCTATTAATGCAGAGAGTTGTAGTCTTCTCGCAGAGAAGTATGTAACTTATGATATTGAACCTTGTAAGAAGGAAAAGGAAGCTCTAGGAAATTTGGGTTTTCATTGCGATTTATGCGATGTGGAATTTCAAGATTTAACAAAGCTATTTCAACATAACAAACAGCATCTACAGCACTCTCAAGCCAGCTTCTTAAAACCAGGAAGTAAGTTTAACTTCTGTCCTTTTTGTGTATGTCGCTTTGATGGTCACTTCGATGATATTGAAATCCATAAGACAGAAATTTCATTGCTTTCTTTCTTTGAATGCCGATATTGCTTAGCAAGACCAAAAACATTTGATGAATTGCTTGAGCATTATAAGGATATACATAAAAATCCAACaccatttttcgattttttcataaattcaaGCACATCTTTGCCAggtattaaaatctattcaggtAAGAAAAAGCATCCATTTCAATGTGATATTTGCTTGCGTAATTTTTCAACAAGAGGTTACTTAAAGTGTCATAGAATAACGCATAGTGGTAAGAAACCTTATGAATGTGAGCATTGCAATAAGAAGTTTTCATATCCAACAAACTTGACTGATCACATGAAAGTCCATACAAGACCGGATTCAAGGCCATTCCAATGTAATATGTGCCCTAAGAGATTTTCAAAGAAGCAATCACTTGCATATCATCGGTATTTACATGCTGGCGACAAACCATATATCTGTAAACATTGTCCAAAGAAATTCTCTGCTCCAGAATATTTAAAAAGACACCTGAATGTACATAATGACAGTTCGGATAATCCACACAAATGCAATCGTTGTGGCAAAATATTTGCATGTAGTTACAATGTAAAAAGGCATATAGAAAAAGTTCATGTCAATCCAGGTCCTGTGTCTTATGCTTGTGACTATTGCGACAGGACATTTGAAAAGAGAGTTTACTTAGTAAGGCATCTAAAGAGCTTAGCTCATAACGAACCTAAAAGACTTAAATGTGATCACTGTGAAAAGACTTTTGCCTTTAAGAATTTGCTAGATGATCATATGATATTCCACAGCAATGAAAATTTAGAAATGCCGACTTGTATATACTGCAGTAAGAAATTTAGCAAGCCGGGCTACTTACGTCGACACATAGTTATGAATCATAAGTGTGAATTTTGTCCGAGAATTTATCAAAATCGAACTGCCTTAAACTCACATCGGCGTGAGCATGTCGGACCTGGCCCACACTCTTGTTACTATTGTGATATAAAATGCGCAAACGCCAAGGAATTTGTGAAGCATATTAAGCTACATACGTACAAGTGTGATTTATGCACAGAAACATTCTCAAAAGAAATGGATTTGAATTTACACAGATTTATGCACTCGGGTGAAAAAATGCATGCCTGTAGCATATGCTCTAGCCGTTTCATGCATTCAAATCGCCTACGAGCTCACTTGAAAGATGTCCATGGAGATCTTGAAGGCAGCTTAAGCTTATGGTATGACAATCCAATCCAAAATCAAGATCTTCCACCGCCAGAAGATATTAAAGCAGAACCAGATTACTTAACACTACCCAATGAAACAGGATTTTTTTGCAAGGTGTGCTCCACTAAATTCGAGGACTTAAAAGACTTGCGATTGCATATTATCGAAGCTCATATaaaaaatgaagagaaaacCTTTAAGTGCAGCTACTGTGATCAATCCTTTAAGAAAATGTTTGATTTAAATAAGCACAAAAAAGAATCACACGCTGCAATTGTTGAAAAGCCGCACAAATGTGATATGTGCTCAAAGGAATTCTACAATAAACAAGCATTAAGATATCATAGATATAATCATACTGGTGAGAAGCCATTTCCTTGCGATCAATGTGGAAGGAACTTTACTCGCCCGTATATTTTACAGAAGCATAAGGAGCAGGTTCATACGCCTCCAAGCTTGAGAAGTCATCGATGCAGTTTGTGCCCCAAGAGTTTTGTGTCGAAGTTTTTCTTAGAAAAACATTTGCGAGTCCATAAAATACGAGACGAAAATGGCGGAGTTTGTAAAAGAcagaaacaaaatataaaaaaagtattgataaaaaagaaaaatgatatTTGTTCCTAA
Protein Sequence
MDSINAESCSLLAEKYVTYDIEPCKKEKEALGNLGFHCDLCDVEFQDLTKLFQHNKQHLQHSQASFLKPGSKFNFCPFCVCRFDGHFDDIEIHKTEISLLSFFECRYCLARPKTFDELLEHYKDIHKNPTPFFDFFINSSTSLPGIKIYSGKKKHPFQCDICLRNFSTRGYLKCHRITHSGKKPYECEHCNKKFSYPTNLTDHMKVHTRPDSRPFQCNMCPKRFSKKQSLAYHRYLHAGDKPYICKHCPKKFSAPEYLKRHLNVHNDSSDNPHKCNRCGKIFACSYNVKRHIEKVHVNPGPVSYACDYCDRTFEKRVYLVRHLKSLAHNEPKRLKCDHCEKTFAFKNLLDDHMIFHSNENLEMPTCIYCSKKFSKPGYLRRHIVMNHKCEFCPRIYQNRTALNSHRREHVGPGPHSCYYCDIKCANAKEFVKHIKLHTYKCDLCTETFSKEMDLNLHRFMHSGEKMHACSICSSRFMHSNRLRAHLKDVHGDLEGSLSLWYDNPIQNQDLPPPEDIKAEPDYLTLPNETGFFCKVCSTKFEDLKDLRLHIIEAHIKNEEKTFKCSYCDQSFKKMFDLNKHKKESHAAIVEKPHKCDMCSKEFYNKQALRYHRYNHTGEKPFPCDQCGRNFTRPYILQKHKEQVHTPPSLRSHRCSLCPKSFVSKFFLEKHLRVHKIRDENGGVCKRQKQNIKKVLIKKKNDICS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01431269;
90% Identity
iTF_01431269;
80% Identity
-