Basic Information

Gene Symbol
-
Assembly
GCA_033459515.1
Location
CM065936.1:10570134-10578989[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.0044 0.28 12.0 1.1 3 23 207 228 206 228 0.96
2 23 0.17 11 7.0 0.3 1 22 608 629 608 629 0.95
3 23 0.94 61 4.7 0.3 1 23 671 694 671 694 0.92
4 23 0.0019 0.12 13.1 1.8 3 21 705 723 705 724 0.96
5 23 1.2 74 4.4 0.1 2 23 732 754 731 754 0.89
6 23 1.3 87 4.2 0.2 3 23 775 796 773 796 0.92
7 23 0.00096 0.062 14.1 1.9 1 23 802 825 802 825 0.96
8 23 0.099 6.4 7.7 0.0 1 23 851 874 851 874 0.90
9 23 0.0043 0.28 12.0 3.5 1 23 879 901 879 901 0.97
10 23 0.014 0.88 10.4 0.2 1 23 907 930 907 930 0.95
11 23 0.0008 0.051 14.3 1.2 1 23 943 965 943 965 0.98
12 23 0.0042 0.27 12.0 4.3 1 23 1014 1037 1014 1037 0.96
13 23 0.0036 0.23 12.3 1.8 1 23 1097 1120 1097 1120 0.97
14 23 0.0016 0.1 13.4 1.5 2 23 1144 1166 1143 1166 0.95
15 23 0.078 5 8.1 0.2 2 23 1172 1194 1171 1194 0.95
16 23 0.0079 0.5 11.2 0.2 1 21 1238 1258 1238 1259 0.95
17 23 0.00098 0.063 14.1 0.6 1 23 1269 1291 1269 1291 0.93
18 23 8.9e-05 0.0057 17.3 0.3 2 23 1379 1401 1379 1401 0.93
19 23 2.6e-07 1.7e-05 25.3 1.4 3 23 1408 1428 1407 1428 0.98
20 23 0.097 6.2 7.8 1.4 1 23 1446 1468 1446 1469 0.96
21 23 0.15 9.4 7.2 0.0 1 23 1489 1511 1489 1511 0.97
22 23 0.0095 0.61 10.9 0.4 1 23 1517 1540 1517 1540 0.95
23 23 1.9e-05 0.0012 19.4 0.5 1 23 1548 1571 1548 1571 0.96

Sequence Information

Coding Sequence
atgagtGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGATTTACTGCCGATTTTTCCTACCACCAGTTCCGATGACTCGGAACCTCCCGTCCTCGCTTCGAAAATCAAGGATTGCGTGTCCATACAGataacCGAAAATGACGACTTGCCGACAAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGGCATGTATTCAAGAGTGTGTGTGAAAGGACTCAAAACAAACTACAGTCTCTGATTAATAAAGATGGCAGCCAACTAGAAGAGGTGAAAATAAAGAGTGAGCCATTGTCTGATGAGGCCTATGATGATGGAGTGGTCATTGATGGAGCATACCATGACCATGAGAACGCCACATCAAGTAAAATGCAGCCAGAAGGGCCCCCAATCTTGGCGTCGCTGGGGCTCACGCCGAGGAGTGATAAGGGCATGGAGAGTGAAAAAGACGAAGAAGACGACGACGAGGAGGAGATGACTGAATCTGCTCAATCGTACTCCAAGGTAGCGAACATGCCCGAAGTGTCCATCACCGTGATGCGGCCTTCAGGAGAAACCCTACACGCGCGGCAAGGTATCCAACAGTTAGCCTCCAAAGATTGTCTCGTCTGCGGCAGAACCTACAGGTACTCCCATAATGCCAGGCGACACGAACTCACCGCTCACAGTTTCGATAGGTACACAAATAAAGTTACTAATAAGAAGTCTCACATGCGACTACAACCTAAACTGAGACCCAACCCATTTAATCCTAAAGCAAGATTAATGCCAAATCCTATTAGCCACAAAATGCAATTTATACCTAAGAATATACCGGCTAAAATTACACCACAGAAAGTTATTACCCCACCGAAACCCATACCTATAAAGACAGCAAAAGCTCCACAAAATAACCTGCCGTATCCACTTCGAATTAAAGCGCTTAAGGATCTACAAATAAAGAAGAAAGAAccgcaaatattaaaaacattgcttACCACAAAACCGGAAGTTTTAGTATCAGAACCAGAAATTATAAATTCCGGCCCAGAGAGTCCGGAGACATTGATATCTGAACCGGAAATTGCGTCATTCCAAGTAGAAACTATTTTGTCCGAACCGGATCCCGAGGCTTACGACCATCACCAGGGCGACGATGAAGCGGATGGTGATATGCACAATAATCAGAATCAAAATTACGACACTGTCGATATGGATTCTGagaatgaaattgaaattgcCAGACAACGAGAAAATCATCATGATGGTGACGAACAAAGTGAAATGCATGATGATGATAATCACATGGATGGCGGTCACAGTGATAACGACAAAGACCAGAATGATGAGACAGTTGACAGTCAAGATAACATGGTCATCGATGAGAGCGCAGATATCAAAACCGAGGAATATGACGGCGATGACTGTGAAAAAGGTCATGAAGATAGAGATCATGAAGAAAACGAAATGAATCATGACGAAAATGACGAGGATGACGAAGACATGCCGCCGATAGGTATAGCACCTGTTGTAGAAATAAACGAAGATCTCCAAGGTAATTCATACAATAGTGAACTTAACGAagaggaagaagaagaagaaatggATGAAACGGGTGACCCTAATGACACCATCGACGACTCCATGAAGGAACTTGACCCTGACAAATTGTATGTCACGAAAACACAAAGGGACTTTATCATGAAGTACCGCGACGTCATTGAGCAAATCAACACGAAGCGATGCTTGTGCTGTGATCGAGAACACCCGCGAAGGAAAGCCGTTATTCAGCATTTACAGAAAAATGGGCACAAGGTCCCCAAACATACGTGTTATAATTGCGTCATAACCTTCGGTCATATTGGCGCTCTACTTAGCCACATGAGATCGAATTCCTGTACAGATCtctggaaaataatttacaacgaAAATGGAATCACCGACGATTTGGTTTTGGAAGATGAGCCAAAGGACAACAAAGTCCAGTATAAGGATATTTTCAACGCGAGGTCATATGCTTGCAAGCTGTGTCCGGCTAAATTCCagctaaaacaatttataatgaaacataTGCTAGATGTTCATGAAGACGGACAGTCCAGAGTGCCCCTTGGTTGCGTCCACTGTCGAGCCAGATTCAAGGATAAGAGTTTACTAAAGAAACATATACGTAACGGCGAGTGCACGGTGTATATATCCTGCGATTTGTGTTCCGAGAAATTTGGAAATATGCAGGATTTCAATGACCACGCCTTGGCGGTCCACGCCGGCAGCTTTGATCAGTCTGACAACGCTAGTAAGTGTGTCGACGGCCGGCCGACAGACTGTCCTCTATGTGGCAAAAAGAACAGCAACTATCCAATATTAGTAAAGCATTTGAAAACAGTGCACAATGAAGAGAAACCTCATTACTGCCAGCATTGTGACGCTAAGTACGAGCAAGCTGCCGACCTCAACAAACACATTTACACAGAGCATTCTGACAGGACGTTGGGCATACAGAGTAACGAGCCCGACATGTCTCTCGTCAAAGAGGAGGCTGAGGAATACCACTATTCGTGTACAGAATGCAACGCTATCTTCGAGACAGTGGACGCGTGGACCGATCACCAAGTGGCGGAGCACAACCAGGTGGCGCACCACTGCGACCAGTGCGACAAGAAGTTCCTGCGGCCGTCGGAGCTCGCCGAACATAAGAACACTCATCTGCGAGTCAAATTCTATCCGTGCAGCGTCTGTTCCAACTCGTACAGCACCCCACAGAAACTCTCCGAACACGTACAACAAGCCCATCCCGGTGTGAGATCGTTGTCTAACACGGAGTCCGAATTTTATTGCGAGATATGTATCAGATCATTCAAGAGTCGTCAAGCGTATTCCAATCATATGCGTATTCACGCGAAGGTTCCCACCACTAATAGAAAACCGGGTGACCCGAAAGGTTTTGCGCCGCAAATTATCGGAAAGCCCATCAAACAGTTTTCGATGATGCAGCCTGGGTTTGTTTCATTCAAGCCGAGTTATAACGTTCCTAATGCTCCTTACTGTTGCGATTTGTGCGGCAAAGGATTCATGCACAAAAAGAACATTTGGAAACATAAGAAGGTGTTACATGCTGATATTTTGAAAGATCGAAATGACAGCGAAGAAAATACTATGCAAGCGTCAACCGAAGAGGAAGAATTTAATACTGAAGAAAATGGCACCGGTTTGTCGACGCCGCAATTTAATAGTTTCAATTTTACCAACTTCACAAGTAATTCCCAACAATCACAGTCGGACGGCTTTCCTTACTCGTGTGAGCTGTGCTATCAGCGCTTCCCGCTGCGCAGTAGCTTATGGAAACATAAACGGAACAAGCATGGTATCATAAGTTCTTTCGATGGCTCTGAGGGTCAATCGCAACCGTCAGGTGACGGTAGCAGTAGGTCCAGTTGTACAATTTGCAAAATAACCTTTGCGGACAAGAAATCCTATTACAGACACAGAAAGAACGTCCACAAATCCTCCGTGCAAATGTGCAAATTATGTGGAAAACCACTCAACTCTACGTTGGAGCTGTACGAGCATTTAAAATCGGCTCACGCACAGGAACTATTGGGCTATAATGCAAACCAAGGTTCGAGTAAATCTCAAGAACCTACACAAGAAATGGAACCGGAGTACGATAACGACCAGGAGGCCGTTGACCCGAGCGTCGATTATCAAGCTAGATATCCTTGCGACACTTGTGGTAAACAGTTCGTCGGATTGCTCGCTTTGCAAAACCATCAATGTATCAATCAACTCCCAAGTCAACCGCAAACGTTTGATTGCGAAATTTGTCACAAGAGTTACACGTCCATTGCGGCTTTGAAGAGTCATCGCGGTTGGCATTTACGCTCACCGGACGGCAAGGCGGCCGCCAATAATTCCGGTTTATGGATGCCCCAGCACAAGGTGACGAACAAAATAAGCAAATACGAGGTCGTGGATCCCTCGCAGTTAGCTCGAGTCACGCACTCGACACCCGCCTCCGTCGCCAAGAGAAGATTACCGCCCGAAGTCGAGGTGACAGTGGTCAATCCGAACAAGAAATTGCGGTCCGACGACTCCATAGAAATGGAGCAGCACAGTTCCAGCGCCCTCGAAGACAGATACTGCACCATTTGCGACAAAGAGTTCACCAAACGCGCCGCATACCAGCGACACATGGACGAGGTCCACCAGCCCAACTCCGTGTTCTGTCCCGTCTGCGACAAGAGTTTCACGCGGAAGTCGACGCTGCTGGTGCACATGAAGAAGCATTACGAAGGCGGCGAGGGCAGTTCGTCGACGGCGATGATGGACGAGGACTCGTACTCGTGCGACCTGTGCAGCGCGCAGTGCGACAGCGCGGCGGGGCTGCGCGCGCACCGCTCGCGGCACCACGCCTCCGACTCGGGCGACTCGGACGACGGCGCCGTGCCCGCGCAGCAGCCCGGCGAGTTCACGTGCGCGCAGTGCGGCGACGGCGTGGCCACGCCCCGCGACCTCATCGCGCACCGCACCATGCACTCCACGCCCACCAAGTTCTTCTGCAACATCTGCAAGGTGTACTTCGCCCGGGCCATCGACCTGTCCTCGCACACGCGCGCGCGACACTCCGACAACGACAAGGTGTTCTTCCCCTGCTCCATGTGCGACCGCTCCTACATGAACAAGAAGAGTTTACAGAGACACATCGAGATGGCGCACTGA
Protein Sequence
MSVNYDRVCRLCLSSRGDLLPIFPTTSSDDSEPPVLASKIKDCVSIQITENDDLPTNVCRKCMDNVNNWHVFKSVCERTQNKLQSLINKDGSQLEEVKIKSEPLSDEAYDDGVVIDGAYHDHENATSSKMQPEGPPILASLGLTPRSDKGMESEKDEEDDDEEEMTESAQSYSKVANMPEVSITVMRPSGETLHARQGIQQLASKDCLVCGRTYRYSHNARRHELTAHSFDRYTNKVTNKKSHMRLQPKLRPNPFNPKARLMPNPISHKMQFIPKNIPAKITPQKVITPPKPIPIKTAKAPQNNLPYPLRIKALKDLQIKKKEPQILKTLLTTKPEVLVSEPEIINSGPESPETLISEPEIASFQVETILSEPDPEAYDHHQGDDEADGDMHNNQNQNYDTVDMDSENEIEIARQRENHHDGDEQSEMHDDDNHMDGGHSDNDKDQNDETVDSQDNMVIDESADIKTEEYDGDDCEKGHEDRDHEENEMNHDENDEDDEDMPPIGIAPVVEINEDLQGNSYNSELNEEEEEEEMDETGDPNDTIDDSMKELDPDKLYVTKTQRDFIMKYRDVIEQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTDLWKIIYNENGITDDLVLEDEPKDNKVQYKDIFNARSYACKLCPAKFQLKQFIMKHMLDVHEDGQSRVPLGCVHCRARFKDKSLLKKHIRNGECTVYISCDLCSEKFGNMQDFNDHALAVHAGSFDQSDNASKCVDGRPTDCPLCGKKNSNYPILVKHLKTVHNEEKPHYCQHCDAKYEQAADLNKHIYTEHSDRTLGIQSNEPDMSLVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCDKKFLRPSELAEHKNTHLRVKFYPCSVCSNSYSTPQKLSEHVQQAHPGVRSLSNTESEFYCEICIRSFKSRQAYSNHMRIHAKVPTTNRKPGDPKGFAPQIIGKPIKQFSMMQPGFVSFKPSYNVPNAPYCCDLCGKGFMHKKNIWKHKKVLHADILKDRNDSEENTMQASTEEEEFNTEENGTGLSTPQFNSFNFTNFTSNSQQSQSDGFPYSCELCYQRFPLRSSLWKHKRNKHGIISSFDGSEGQSQPSGDGSSRSSCTICKITFADKKSYYRHRKNVHKSSVQMCKLCGKPLNSTLELYEHLKSAHAQELLGYNANQGSSKSQEPTQEMEPEYDNDQEAVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQLPSQPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTNKISKYEVVDPSQLARVTHSTPASVAKRRLPPEVEVTVVNPNKKLRSDDSIEMEQHSSSALEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLVHMKKHYEGGEGSSSTAMMDEDSYSCDLCSAQCDSAAGLRAHRSRHHASDSGDSDDGAVPAQQPGEFTCAQCGDGVATPRDLIAHRTMHSTPTKFFCNICKVYFARAIDLSSHTRARHSDNDKVFFPCSMCDRSYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00429234;
80% Identity
-