Basic Information

Insect: Thera obeliscata
Gene Symbol: Hr39
Assembly: GCA_947578465.1
Location: OX387926.1:12573932-12600329[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 3 2.4e+04 -8.2 11.9 97 163 214 310 127 354 0.53

2 4 4.6e-08 0.00037 20.4 0.1 1 21 442 462 442 475 0.91

3 4 1.7e-12 1.4e-08 35.0 0.0 157 238 500 589 470 591 0.67

4 4 7.9e-63 6.3e-59 200.8 0.0 203 408 608 814 596 814 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	3	2.4e+04	-8.2	11.9	97	163	214	310	127	354	0.53
2	4	4.6e-08	0.00037	20.4	0.1	1	21	442	462	442	475	0.91
3	4	1.7e-12	1.4e-08	35.0	0.0	157	238	500	589	470	591	0.67
4	4	7.9e-63	6.3e-59	200.8	0.0	203	408	608	814	596	814	0.94

Sequence Information

Coding Sequence: ATGAATACCGCGATGTCAAGTGACGCGGATGCTGTGAAGGTAGAGGGGGGACACGTCTCCGTCACTACCATAAGCATGTCAGGCCCAGAAACGAGCAATGGTCAATTCTCGTATAGTTCAAGCGGAGTGCGCATCAGTGTGTCTTCGGTGCCACATGACGAAGACTCCACTGATGCCGAAATCTCCAAAATCGACTTCacacaacatcaatatgagGTAAACATGCGTAACAAGCAACAGCGATCGTCCAGCGGAGCTCAGTACGACGGACAGGCCAACGATCGGGAGCGGCCCATGTCCTGGGAAGGCGAGCTCTCTGATTCTGAAATGGTCATCGATACCAATGTCAATAATGATGAAAACAGCAACTCCTTAGATCTGCAGTCCTCTCGAGATTCGATAGACACCCTCCGCAACGTAACGATCAAACAAGAGCCGATGAAGAGCGAAATGTTCCAGAGTTTGGACGATCAGAGGGTACTCGACTTGAAGTTTACGGCGCCATTGCAGCAGCACCAGAGGAGTCATAGTATGAACAGGATACCACTGCTGACCGATTCTCCCCTATCCCTGCCTCGAAGACCGTCGTCGCCCACAAACAGCGCCAAATCCCTCGCGCTCTCAGACCAAGGCTCTATGCCGATGCCGCACTCTTCCATAGGGGAGATACAGAACTTGACTATCAAGAAAGAAACGCTATCAGAGTTAAAATGCGAGCCGTCGCTAGGCATGGAGAAGTTGCTAGGCACAGCCCTCGGCTCGCCTCTCACGGGAAGGATGCAGCGCGTCCAGTCCAGCGCCAGCACTGACTCCGCCGTACATTCCATGTACACACACAGTGTGTACAGCAGTCCGTCAGCCAGCCCGCGAGCGACGCGTCACTACACGCCGTCTCTTTCTCGCAACAACAGCGACGCATCGCACTCTTCCTGTTACTCCTACAGCTCAGAGTTCTCGCCTACACATTCCCCAGTCCAGGGTCGTCACCCTCACGTGGTGTATAGAGAGGCGACGGGCGTGTTCCCCGCGTCGCCGGCGCATGATGAAGACACGGAGACGGACGACAGGCTGCATCATCATCAGGGCATCAGTCGGCAGCAGCTTATCAACAGTCCATGTCCGATATGTGGCGACAAAATCAGCGGGTTCCACTACGGGATATTCTCATGTGAATCCTGCAAGGGGTTCTTTAAGCGAACAGTGCAGAACAGGAAGAACTATATGTGCTTACGAGGCAGCAACTGCCCCGTCACTGTGGCGACCAGGAAGAAATGCCCCGCGTGCCGGTTCGACAAGTGTTTGAACTGTGGGATGCGGTTGGAAGCTATAAGAGAAGACAGAACTCGAGGCGGTAGATCAACGTACCAATGTTCATACACACTATCCGGCGCCGCGTCTACCGGCTCGCTTCTCTCCGCGCATGTACCTACCACACTGCGGCACGCTTCCAGCCTCAACTGCGTGAACGGTCCAGGGTCATACAACAGTCGAGGGGAATCGAGTAACAGTCGACTCACGCCTGATATTCCGCCGTTATTGCAAGAAATAATGGACGTGGAACACCTATGGCAGTACAACGAAACCGAACTGAATCGACTAGGCAAGTCCACTGGTAGTCCGTCCGCCAACCCATTGCTAGCCGCCAGTGGCATCACCGCACAGAACTCAAGCCCGGACTTCCTAGCTGACCTCTGCAATATAGCTGACCATCGCCTTTACAAGATAGTCAAGTGGTGCAAGAGCCTACCCTTGTTCAAGAATATTTCGTCCACTGGTGGTCCGTCCGCCAACCCATTGCTAGCAGCTAGTGGTATCACCGCACAGAACTCAAGCCCGGACTTCCTAGCTGACCTCTGCAATATAGCTGACCATCGCCTTTACAAGATAGTCAAGTGGTGCAAGAGTTTGCCCTTGTTCAAGAATATTTCGATAGACGACCAAATCAACCTGCTAATCAACAGTTGGTGCGAGTTGTTGGTGCTGTCGTGTTGTTACCGCGGCGTCAGTACGCCGGGGGAGGTGCGAGTGGGCGGCGGCAGAGGAATCACGCTGCAGCACGCCACCAAGTTAGGCTTGACGCCGTGCATAGAGAGGATGCTAAGCTTCACAGACCATCTGAGAAGGCTTCGAGTCGACCGATACGAATACGTGGCACTGAAGGTCATCGTTCTCCTCACTTCCGATGCTCCAGATTTGCGTGAATCGGAGAAAGTCCGCGCGTCGCAAGAGAAAGCTCTCGCTGCATTGCAAGCGTACATCGCAGCGCATTCGCCGCAAACACCCGCTAAGTTCGGAGAACTCTTGCTCAGAATCCCGGAGTTGCAGCGGACTTGCCAATTCTTCATGCAAGTCGGCAAAGAGATGCTCAATCCAGCGAACAAGAACAAAGATGGCGAAGGGCCGAGCTTCAATCTACTCATGGAACTACTCAGGGGAGACCATTGA
Protein Sequence: MNTAMSSDADAVKVEGGHVSVTTISMSGPETSNGQFSYSSSGVRISVSSVPHDEDSTDAEISKIDFTQHQYEVNMRNKQQRSSSGAQYDGQANDRERPMSWEGELSDSEMVIDTNVNNDENSNSLDLQSSRDSIDTLRNVTIKQEPMKSEMFQSLDDQRVLDLKFTAPLQQHQRSHSMNRIPLLTDSPLSLPRRPSSPTNSAKSLALSDQGSMPMPHSSIGEIQNLTIKKETLSELKCEPSLGMEKLLGTALGSPLTGRMQRVQSSASTDSAVHSMYTHSVYSSPSASPRATRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVVYREATGVFPASPAHDEDTETDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGSNCPVTVATRKKCPACRFDKCLNCGMRLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHVPTTLRHASSLNCVNGPGSYNSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNETELNRLGKSTGSPSANPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISSTGGPSANPLLAASGITAQNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQINLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLQHATKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLRESEKVRASQEKALAALQAYIAAHSPQTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKNKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01161468;
90% Identity: iTF_01429096;
80% Identity: iTF_01429096;