Tmat002545.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Thalpophila matura
Gene Symbol
-
Assembly
GCA_948465475.1
Location
OX419185.1:12033652-12038848[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.63 43 5.2 0.0 8 21 71 84 70 85 0.86
2 7 0.35 24 6.0 0.2 3 21 158 176 158 177 0.93
3 7 0.00033 0.023 15.5 0.0 1 23 197 219 197 219 0.95
4 7 0.00089 0.061 14.1 0.5 1 23 225 247 225 247 0.99
5 7 3.2e-07 2.2e-05 25.0 2.2 1 23 253 276 253 276 0.97
6 7 3.4e-06 0.00023 21.7 3.4 1 23 282 305 282 305 0.95
7 7 0.092 6.3 7.8 0.4 2 19 312 329 311 330 0.83

Sequence Information

Coding Sequence
ATGACTTCTCTTTTATTACTTAAGTCAATGCTGTTTGCAAATGCTCTCCAAAAGAGTAAAAAGAAGAAGAACAAGATCAAAAAAACCCCTAAAATAAAGAAATTAAGCCACAGTATGTGCAGGATATGCAATGACGAAAAAGGAGATATTCCGATATTCAACAATTTTGTACAACCCAATATTCCTGAAGAAATACATAATTTTTCTGGTATTACTTTAACTAATTCAGACAATCTATCAAAACACATGTGTCAAAGCTGCTTGGACCTGTTAAATGGATGTATAATGTTCAGAGAAATGTGTCAGAGGTCTAACAAACAGATGATTGAAATACCCATAAAGACAGAATATAATCAAGACTGTCAGAATTATGAAGAGGATCATTATGCTAAAGCAGATAGTGAAGACTCTTATAACATTCCATCACCAACATTTTCTGTGGATAACTCTGAACTTCTTTCTCTCTGGGGGTGCTCTACCTGTGGTGAAGAATTCCATGTTATGGCTACCTACAGCAGACATATAATCAAGTGCAATGCCCAATCAAGTGATGTGCCCAAACCACCAGAGGAAATAACTAAGAGGAAGTTCCTATGTGACATCTGTGGAAAGACTGCATTTTCTAATGCCAGTCTTCTTGTTCATATGGCCATCCACGAAAATGTGTTTCCTTTCAAATGCGACGTGTGTCCGTACCAAGGTCGAACAATGGATCTGCTGAAGGTACACAAGAGATCCCATTTGGTTGATAAACCGTTCAAATGCACACAATGTCCTAAGGCAACAACTACGTCAAGTAATCTTGCTAAGCATATGCGACATGTTCATAGCACTACAAGACCGTTTAAGTGTACTTATTGTGACAAGGCTTTCTCATACCAACATGACATGAAAAGGCATGTAAAAGATATTCATTTAAGGCAAGGCACCGTGGAATGCGATATCTGCTATAAGAAGTTTAATACTAAGAAAATTTTACAGGGTCACAAATGGAAAATTCACAAGATTAAAGGCGAACGACAGGGTCGTCTGCCGTCGTACTTACAATGTCAAATGGAAGAGCCAAATAATGAAAACAACATTAATGACAACACGAATAACTGTGATCCTAATTATTGA
Protein Sequence
MTSLLLLKSMLFANALQKSKKKKNKIKKTPKIKKLSHSMCRICNDEKGDIPIFNNFVQPNIPEEIHNFSGITLTNSDNLSKHMCQSCLDLLNGCIMFREMCQRSNKQMIEIPIKTEYNQDCQNYEEDHYAKADSEDSYNIPSPTFSVDNSELLSLWGCSTCGEEFHVMATYSRHIIKCNAQSSDVPKPPEEITKRKFLCDICGKTAFSNASLLVHMAIHENVFPFKCDVCPYQGRTMDLLKVHKRSHLVDKPFKCTQCPKATTTSSNLAKHMRHVHSTTRPFKCTYCDKAFSYQHDMKRHVKDIHLRQGTVECDICYKKFNTKKILQGHKWKIHKIKGERQGRLPSYLQCQMEEPNNENNINDNTNNCDPNY