Basic Information

Insect: Thalpophila matura
Gene Symbol: -
Assembly: GCA_948465475.1
Location: OX419185.1:12611823-12638399[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 8e-05 0.0055 17.4 2.2 1 23 425 447 425 447 0.97

2 20 0.0042 0.29 12.0 0.6 1 20 453 472 453 475 0.94

3 20 2.1e-05 0.0014 19.3 5.6 1 23 494 516 494 516 0.98

4 20 9.7e-05 0.0067 17.2 4.1 1 23 522 544 522 544 0.99

5 20 3.7e-05 0.0025 18.5 5.3 1 23 550 572 550 572 0.97

6 20 5.9e-06 0.00041 21.0 7.2 1 23 578 600 578 600 0.97

7 20 7.1e-07 4.9e-05 23.9 2.9 1 23 606 628 606 628 0.97

8 20 0.0001 0.0069 17.1 6.7 1 23 634 656 634 656 0.97

9 20 0.0001 0.0069 17.1 6.5 1 23 662 684 662 684 0.97

10 20 4.9e-07 3.3e-05 24.4 1.9 1 23 690 712 690 712 0.98

11 20 4.9e-05 0.0034 18.1 7.9 1 23 718 740 718 740 0.98

12 20 2.5e-05 0.0017 19.0 6.6 1 23 746 768 746 768 0.98

13 20 2e-06 0.00014 22.5 4.2 1 23 774 796 774 796 0.98

14 20 2.2e-05 0.0015 19.2 5.1 1 23 802 824 802 824 0.96

15 20 2.1e-06 0.00015 22.4 5.0 1 23 830 852 830 852 0.98

16 20 3e-06 0.00021 21.9 6.0 1 23 858 880 858 880 0.98

17 20 5.9e-05 0.004 17.9 7.9 1 23 886 908 886 908 0.97

18 20 1.4e-05 0.00099 19.8 7.7 1 23 914 936 914 936 0.98

19 20 0.00073 0.05 14.4 0.3 1 23 943 965 943 965 0.96

20 20 0.31 21 6.2 5.1 1 23 976 998 976 998 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	8e-05	0.0055	17.4	2.2	1	23	425	447	425	447	0.97
2	20	0.0042	0.29	12.0	0.6	1	20	453	472	453	475	0.94
3	20	2.1e-05	0.0014	19.3	5.6	1	23	494	516	494	516	0.98
4	20	9.7e-05	0.0067	17.2	4.1	1	23	522	544	522	544	0.99
5	20	3.7e-05	0.0025	18.5	5.3	1	23	550	572	550	572	0.97
6	20	5.9e-06	0.00041	21.0	7.2	1	23	578	600	578	600	0.97
7	20	7.1e-07	4.9e-05	23.9	2.9	1	23	606	628	606	628	0.97
8	20	0.0001	0.0069	17.1	6.7	1	23	634	656	634	656	0.97
9	20	0.0001	0.0069	17.1	6.5	1	23	662	684	662	684	0.97
10	20	4.9e-07	3.3e-05	24.4	1.9	1	23	690	712	690	712	0.98
11	20	4.9e-05	0.0034	18.1	7.9	1	23	718	740	718	740	0.98
12	20	2.5e-05	0.0017	19.0	6.6	1	23	746	768	746	768	0.98
13	20	2e-06	0.00014	22.5	4.2	1	23	774	796	774	796	0.98
14	20	2.2e-05	0.0015	19.2	5.1	1	23	802	824	802	824	0.96
15	20	2.1e-06	0.00015	22.4	5.0	1	23	830	852	830	852	0.98
16	20	3e-06	0.00021	21.9	6.0	1	23	858	880	858	880	0.98
17	20	5.9e-05	0.004	17.9	7.9	1	23	886	908	886	908	0.97
18	20	1.4e-05	0.00099	19.8	7.7	1	23	914	936	914	936	0.98
19	20	0.00073	0.05	14.4	0.3	1	23	943	965	943	965	0.96
20	20	0.31	21	6.2	5.1	1	23	976	998	976	998	0.99

Sequence Information

Coding Sequence: ATGAATCAGGATCACCATAGTATGAATACGGGTGGTGGCCAGCCTCCGGGAAGCTCTGAGTCACAGGTCCAAAGAGTGCAAGCCGCACAGCAGCAACAGCAGAATAACTTGCCTGCCACGACGTCTGCTACTGATTTGCGAGTGAACTCGGCAGCAGTAAACGTCGCTTTGTCTAGTGTAGCAAAGTATTGGGTGTTTACAAATTTATTCCCTGGGCCGATACCGCAAGTGTCCGTGTACGGATTGCCTGCTGGCGCCAGGATTGAAAATGGGAAGCCTGTCCAGGATCTTGGTCAAGCTCATGCCAGTATACTGAATGGTGATCCAAATATTATACTTGGGCATCATGCCGGTCAGTCCCAAGTCACAGTATCTGCTGCTGGTGGACAGCAGATACCAGTCTCACAGATCATTGCCACACAGTCCGGACAAACTCATGAAGCTCTTGTGGCCCACAGTCAGCAGGCCGAGCTGGCGGCGGCCCAGGGCGCCGGCAACAATGCGCAGGTGTCAGTTAGTGCTGGCCAGGGCACTCACCAGGTACCCAATAACCGGGTCGAGTTTGTACAACACCATAACATTGATATGGGACACCATACACAACAACACATAATGCAGCAGCAACTCATGGCTTCGGCGCGGCCTGAACACACCAACCAACAGATTCAACTGACGGTAAGCGAGGACGGCATAGTGACGGTGGTGGAGCCGGCGGGAAACAAAATGGTGGACAAGGAAGAGTTACACGAAGCCATCAAGATGCCCAACGACCATACCCTCACCGTGCATCAGTTGCAGCAAATAGTGGGACAACAGGTAATAGACAGCGTAGTACGCATAGAGCAAGCGACCGGTGAGCCGGCGAACATCCTAGTGACCCACAACCCTGACGGCACGACCTCTATCGAAGCCAGTGCCGCGGACCCTTTGATCGTCAAGGACGAGAAAAATTCTAACAAAATAGAGACGGCACAGTTCGCTATACCTACTGAGATAAAGGATATAAAGGGCATAGACTTGAAGAGTGTGGGGGCCATGGGAATGGAAGGTGCTGTGGTGAAGATCTCGGCTGGCGCGTCGGAACACGACCTTCACGCAATGTATAAAGTCAATGTGGAAGATCTCTCACAGCTGCTTGCTTACCATGAAGTGTTCGGAAAACTTAATTCGGAAGGTCAGCAACAACAAGCAAAGGTAATAAGCGAGGTGGAAGTGGACGCAGAAGCGGGCACCAGCGCCGGCATGTCAGAAGCAGAATCCTCACCCGGCCATCACTCGTGCGATATTTGTGGGAAAATATTCCAGTTCCGATACCAACTTATTGTTCATAGGCGTTATCACGGCGAAAGTAAACCATTCACGTGTCAAGTTTGCGGTTCCGCGTTTGCAAATCCTGTCGAATTGTCGAGGCATGGGAAATGTCATCTTGCTGGAGACCCGAACGAAAGACATGCCAAGAGGATGGCGCAAGATAAGCCATATGCTTGCACTACTTGCCACAAAACGTTCTCCCGTAAAGAACATTTGGACAATCACGTTCGAAGTCATACTGGAGAAACTCCTTACAGATGCGAATTCTGCGCGAAGACTTTCACCCGTAAAGAGCACATGGTCAACCACGTACGGAAACATACGGGCGAAACTCCGCACCGATGTGACATTTGCAAGAAGAGTTTCACCAGGAAGGAACACTTCATGAACCACGTCATGTGGCACACAGGTGAAACGCCGCACCATTGTACAATATGCGGAAAGAAGTATACTAGGAAGGAGCATTTAGCGAACCATATGCGATCTCACACAAACGATACTCCGTTTCGATGCGAACTGTGCGGCAAGTCGTTCACGAGAAAGGAACACTTCACCAATCACATACTGTGGCATACGGGGGAAACTCCGCACCGTTGCGACTTCTGTTCGAAGACGTTCACTCGTAAGGAGCATCTCTTGAATCACGTTCGCCAGCACACGGGCGAGTCGCCTCACCGCTGCAACTTCTGCAGCAAATCGTTCACGCGCCGGGAACATCTCGTCAATCACGTGCGGCAACACACAGGGGAAACGCCTTTCCAGTGCGGCTACTGTCCTAAAGCGTTCACGAGGAAGGACCATCTCGTGAATCATGTCCGTCAGCATACAGGGGAATCCCCGCACAAGTGCTCGTTCTGCACAAAATCGTTCACTAGAAAGGAGCACTTGACGAATCACGTGCGACAACACACGGGCGAGTCGCCGCACCGCTGTACTTACTGCGCAAAATCCTTCACGAGGAAGGAACACCTAACCAATCACGTCAGACAGCACACGGGTGAAACGCCACACAAGTGTACGTACTGCCCGCGGGCGTTCGCGCGCAAGGAACACCTCAACAATCACATACGACAACACACCGGCGTCACGCCGCACGCCTGCTCCTACTGCACCAAGAGTTTCACCAGGAAAGAACATCTCGTTAATCACGTTCGGCAACACACGGGCGAGACTCCGTTCAAGTGTACGTACTGTTCAAAGTCGTTCTCTCGTAAGGAGCACCTCACGAACCACGTGAACCTTCACACGGGAGAGACGCCGCATAAATGTCCTTTCTGCACCAAAACATTCTCCAGAAAAGAGCACTTGACCAATCACGTCAGAATTCATACGGGCGAGTCTCCGCACCGCTGCGACTTCTGCCAAAAGACGTTTACGCGCAAGGAGCACCTGACGAATCACCTGAAGCAACACACCGGCGACACGGCGCACGTCTGCAAGGTCTGCTCCAAGCACTTCACAAGGAAAGAACATCTTATCACGCACATGAGGTCGCACAGTTGCGGCGAGCGTCCATTCAGTTGCGGCGAGTGCGGCAAATCTTTCCCGTTGAAAGGCAACCTACTATTCCATGAGCGATCACACAACAAGAACAACGCTAATGCTAATAAACAGTACCGGTGTGAAGTATGCTCTAAGGAGTTCCTCTGTAAAGGCCATTTAGTGACTCATCGGCGCACACACGCGGAATGGGCAGAAGGCGCCGCAAGCGGCGAAACGCCCGCTGAAACAGAAGACTGTACTGACAACAAGTGTATTAAAGTTGAGCCAGAACGAACGGAAAGGAAACATGAAGTCAGGACAACAGTAGAGACGAGACCAGCTGAGAACAATGTTGCACAAACCCAACCAAACACTGCTACTGTAATGATTACCAATAACCAACAAGTGCGTGCTCCGAGCGTAGGCGCGGTGAGCGCGGGCGGTGCGGGCGTGGCGGCCACGTTCGCCCACGGCGTGGCCGCGCAGCACCACGCTGGCGCCAACATCGCGCACCACCCCGTCACCGTCAACTACTAG
Protein Sequence: MNQDHHSMNTGGGQPPGSSESQVQRVQAAQQQQQNNLPATTSATDLRVNSAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPAGARIENGKPVQDLGQAHASILNGDPNIILGHHAGQSQVTVSAAGGQQIPVSQIIATQSGQTHEALVAHSQQAELAAAQGAGNNAQVSVSAGQGTHQVPNNRVEFVQHHNIDMGHHTQQHIMQQQLMASARPEHTNQQIQLTVSEDGIVTVVEPAGNKMVDKEELHEAIKMPNDHTLTVHQLQQIVGQQVIDSVVRIEQATGEPANILVTHNPDGTTSIEASAADPLIVKDEKNSNKIETAQFAIPTEIKDIKGIDLKSVGAMGMEGAVVKISAGASEHDLHAMYKVNVEDLSQLLAYHEVFGKLNSEGQQQQAKVISEVEVDAEAGTSAGMSEAESSPGHHSCDICGKIFQFRYQLIVHRRYHGESKPFTCQVCGSAFANPVELSRHGKCHLAGDPNERHAKRMAQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEFCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCTICGKKYTRKEHLANHMRSHTNDTPFRCELCGKSFTRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTYCAKSFTRKEHLTNHVRQHTGETPHKCTYCPRAFARKEHLNNHIRQHTGVTPHACSYCTKSFTRKEHLVNHVRQHTGETPFKCTYCSKSFSRKEHLTNHVNLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCDFCQKTFTRKEHLTNHLKQHTGDTAHVCKVCSKHFTRKEHLITHMRSHSCGERPFSCGECGKSFPLKGNLLFHERSHNKNNANANKQYRCEVCSKEFLCKGHLVTHRRTHAEWAEGAASGETPAETEDCTDNKCIKVEPERTERKHEVRTTVETRPAENNVAQTQPNTATVMITNNQQVRAPSVGAVSAGGAGVAATFAHGVAAQHHAGANIAHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01030446;
90% Identity: iTF_01247358;
80% Identity: -