Basic Information

Insect: Thalpophila matura
Gene Symbol: Hr39
Assembly: GCA_948465475.1
Location: OX419179.1:17152964-17176325[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 4 2.3e+04 -5.5 8.4 106 191 252 338 170 365 0.53

2 3 6.2e-08 0.00035 20.4 0.1 1 20 442 461 442 468 0.91

3 3 5.9e-65 3.4e-61 208.3 0.0 150 408 493 760 467 760 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	4	2.3e+04	-5.5	8.4	106	191	252	338	170	365	0.53
2	3	6.2e-08	0.00035	20.4	0.1	1	20	442	461	442	468	0.91
3	3	5.9e-65	3.4e-61	208.3	0.0	150	408	493	760	467	760	0.85

Sequence Information

Coding Sequence: ATGGTGATGAGCACCGCGATGAGCAGTGAGGGCGACGCGGTGAAGGTGGAGGGGGGACACGTGTCTGTCACCACTATCAGCATGTCGGGCCCGGAGACCAGTAACGGACAGTTCTCGTACAGTTCGAGCGGCGTACGCATCAGTGTGTCTTCAGTGCCTCATGATGAAGACTCCACCGACGCCGAGATCTCCAAAATCGACTTCACACAACATCAATACGAGGTAAATATGCGTAACAAGAAGAAGCGTTCATCGAGCGGTGCGCACGAAGTATCCAGCAATGAGCGCGAAAGACCCATGTCCTGGGAGGGGGAGCTCTCCGACTCAGAGATGGTCATAGACACCAGTGTTAACAATGACGAGAACAGCAGCTCCCTGGACTTGCAGTCGTCCAGGGACTCGATCGACACGCTCCGCAACGTCAGCATCAAGACGGAGCCCGTCAGCGAGGGCTTCCAGAGCGTGGACGAGCGGGTGCTGGACCTGAAGTACAGCGCGCCGCTGCAGCCGCACCAGCGGAGTCTGAGCATGAACAGGATATCAGTGCTAACAGACGGCACATCGCTCTCTCTAGCGAGGCGGCCGTCCTCTCCGACCAGCAGTGCCAAGTCCCTCGCGCTCAGCGACCAGGGCTCCGCCCACATGCCTCACACTGGACTCGATCAAGTACAGAACCTGACCATCAAGAAGGAGACGCAGTTGTCTGAGTTGAAATGCGAGCAGTCAGTGGGCATGGACAAGCTGATCGGCGCGCTGCACAGCTCCCCGCTGCTGGGCCGCCTGCCGCGCGTGCAGTCCAGCGCCAGCACCGACTCCGCGGTACACTCCATGTACACGCACAGCGTATACAGCAGCCCGTCGGCGAGCCCCCGCGCGTCGCGGCACTACACGCCGTCGCTGTCGCGCAACAACAGCGATGCGTCGCACTCCTCCTGCTACTCGTACAGCTCAGAGTTCTCGCCCACGCACTCGCCCGTACAGGGTCGCCACCCTCACGTGATGTACCGCGAGGCCGCAGCGGCGTATGACGGCACACACGACGACGAGCCCGACGCGCCGGAGGACCGGCTGCACCACCACCAGGGCATCAGCAGGCAACAGCTGATCAACAGTCCGTGTCCAATCTGCGGCGACAAAATCAGCGGGTTCCACTACGGCATATTCTCTTGCGAATCCTGCAAGGGTTTCTTCAAGCGAACAGTTCAGAACCGCAAGAACTACATGTGCTTGAGGGGGGGCAACTGTCCCGTCACCGTCACCACGAGGAAAAAGTGCCCAGCGTGCCGGTTCGACAAGTGCTTGGGATGTGGGATGAAGCTTGAAGCTATAAGGGAAGACCGCACCCGCGGCGGGCGCTCCACGTACCAGTGCTCGTACACGCTGTCGGGCGCGGCGTCCACCGGCTCGCTGCTGTCCGCGCACGCGCCCACCACGCTGCGGCACGCCTCCAGCCTTACTTGTGTAAACGGTCCCGGGTCGTATAGTAGCAGAGGGGAATCCAGTAACAGCCAAGTAACGCCAGAAATACCGCCGTTATTGCAGGAAATAATGGACGTGGAACATCTGTGGCAGTACAACGAGTCCGAACTGAGTAGGCTGGGCAAGTCCACCGGCAGCCCGTCCGCCAACCCGCTGCTGGCCGCCAGCGGGATCACCGCGCACAACTCCAGCCCCGACTTCCTGGCCGACCTGTGCAACATAGCCGACCATCGGCTGTACAAGATCGTCAAATGGTGCAAGAGTTTGCCGCTCTTTAAGAATATTTCGATCGACGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGTTGCTGGTGCTGTCGTGTTGCTACCGCGGCGTGAGCACGCCGGGCGAGGTGCGCGTCGGCGGAGGTCGCGGCATCACGCTGCATCAGAGCGCTAAGTTGGGTCTGACGCCGTGTATAGAGCGCATGCTGAGCTTCACCGACCACTTGAGGAGGCTACGAGTGGACCGATACGAATACGTAGCGCTCAAAGTTATCGTACTACTCACTTCAGACGCGCCGGACCTGCGCGAAGTGGAGAAGGTACGAGCTTCCCAGGAGAAGGCGCTAGCAGCACTGCAGGCGTACATCGCGACGCACTCGCCCGGCACCCCCGCCAAGTTCGGGGAACTGCTGCTGCGCATACCTGAGCTGCAGAGGACTTGTCAGTTCTTCATGCAGGTCGGCAAAGAAATGCTGAACCCAGCCAATAAAAGCAAAGATGGCGACGGACCTAGCTTCAATTTGCTCATGGAACTGTTGCGCGGCGACCACTGA
Protein Sequence: MVMSTAMSSEGDAVKVEGGHVSVTTISMSGPETSNGQFSYSSSGVRISVSSVPHDEDSTDAEISKIDFTQHQYEVNMRNKKKRSSSGAHEVSSNERERPMSWEGELSDSEMVIDTSVNNDENSSSLDLQSSRDSIDTLRNVSIKTEPVSEGFQSVDERVLDLKYSAPLQPHQRSLSMNRISVLTDGTSLSLARRPSSPTSSAKSLALSDQGSAHMPHTGLDQVQNLTIKKETQLSELKCEQSVGMDKLIGALHSSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRASRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVMYREAAAAYDGTHDDEPDAPEDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVTTRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPTTLRHASSLTCVNGPGSYSSRGESSNSQVTPEIPPLLQEIMDVEHLWQYNESELSRLGKSTGSPSANPLLAASGITAHNSSPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLHQSAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLREVEKVRASQEKALAALQAYIATHSPGTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00042698;
90% Identity: iTF_01076559;
80% Identity: iTF_01425208;