Tdiv020436.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tetrapedia diversipes
Gene Symbol
Trl
Assembly
GCA_033822845.1
Location
JAOPTO010002226.1:509184-511535[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.4e-24 1.3e-21 77.5 0.0 4 98 26 116 23 119 0.94

Sequence Information

Coding Sequence
ATGGGAAGCAGCGGCCAACTGTATAGCCTCTCCTGGGGTGAATTTAGTTCATCATTGGCTTCCGCTGTACAGTTATTAAGAGGTCATGGTGATTTGGTTGATGTTACATTAGCTGCTGGTGGACGCAGTTTTCCTGCACATAAGATAGTCTTATGTGCAGCTAGTCCttttctgttagatttattaaAGAGTACACCATGTCAACATCCAGTAGTTATGTTAGCTGGTATAGGGGCAGATGACTTAGAGTCTTTATTGGAGTTTGTATACAGAGGTGAAGTAAGTGTGGAACCATCTCAGTTACCTTCATTACTTCAAGCTGCTCATTGCCTTTGCATTCATGGCTTAACACCACCTACTATATTAACAGaaAATGGAGAAGAGGTGCCTGTGTCAGCAATACCAACAGCAAATGAAGCTCTATCAAAAGAAACAATTAGTCCATATTTTCCATtaaaacgaagaaagaaaagaagaaaatcttCGTCATCTTCTGGAAAATGGCCACGCAATGCTAGTGCTGCTGATAATGAAAATAGACCTGTAGATGGAAGTGATAATGGTCGGTCAGCTAATTATGATCATAAAAATGAAGACAATACTGAACACGGTGATGATACAGCAGCAAACGATCGGTTGGAATATTCGAATCATCGGAGTTGTCATTCACCACGTGCTCAAGAAGCGCAGCCGGTTACGTCAGAAAATTCTCAAGCAGGACCACATCAAGATCAAATATCGGACAATGAATCGCATCTTCACACTTTAATGCCAATGCAGCCATATTCTCCGCTACATATACCACAATTTCCTGGTCCTTTAAATATGGGCTTTCCTCCTGGTTTACCGCTTCCATTAGTTTCTCAGGGTGCAACTGCTGGAACAGCATCCAATCTTACTGGCAATATGAGTTTATCTAAAATACGTGGTGCATCTGACTGTCCAGGCGTTTGTCCTCTTTGTGGTGCTACGTTGCGACAAGCGAGGAATTTACGTAGACATTTGTTATCGTCTTGCAAATATCGATTTAGTAACAATTCGGTTCAGAGTTCCCCAGCTGATACAATGATGGTAGAGATAAAGCCTGAGGTCGAGTTATCCAGTTATAATGAGCAGACTTTGACGTATGGAACTGATAGTGGAAGCAGTACCTGTGAGCAAATAATCTGTAAGCCCAGTCCACTTCCTTCGCCAACATCGCACACACCGAATGTTGTTTCGTCTCAAAGTAACGTTGCGTCACCGACTATCGCTAGATGA
Protein Sequence
MGSSGQLYSLSWGEFSSSLASAVQLLRGHGDLVDVTLAAGGRSFPAHKIVLCAASPFLLDLLKSTPCQHPVVMLAGIGADDLESLLEFVYRGEVSVEPSQLPSLLQAAHCLCIHGLTPPTILTENGEEVPVSAIPTANEALSKETISPYFPLKRRKKRRKSSSSSGKWPRNASAADNENRPVDGSDNGRSANYDHKNEDNTEHGDDTAANDRLEYSNHRSCHSPRAQEAQPVTSENSQAGPHQDQISDNESHLHTLMPMQPYSPLHIPQFPGPLNMGFPPGLPLPLVSQGATAGTASNLTGNMSLSKIRGASDCPGVCPLCGATLRQARNLRRHLLSSCKYRFSNNSVQSSPADTMMVEIKPEVELSSYNEQTLTYGTDSGSSTCEQIICKPSPLPSPTSHTPNVVSSQSNVASPTIAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00684875;
90% Identity
iTF_01424716; iTF_00215809; iTF_00222209; iTF_00873890; iTF_01419330; iTF_00220931; iTF_00222627; iTF_00226951; iTF_00229703; iTF_01419975; iTF_00228072; iTF_01420360; iTF_01420616; iTF_00224233; iTF_00214698; iTF_00226698; iTF_01418058; iTF_00220683; iTF_00229451; iTF_01418443; iTF_00218092; iTF_00223980; iTF_00227628; iTF_00216749; iTF_00224653; iTF_00982637; iTF_01417805; iTF_00227374; iTF_00228335; iTF_00233583; iTF_00221616; iTF_01421232; iTF_00219217; iTF_00215378; iTF_00219474; iTF_00222866; iTF_00224914; iTF_00233330; iTF_00874130; iTF_00216499; iTF_00225587; iTF_00983315; iTF_01419091; iTF_00217428; iTF_00222004; iTF_00230132; iTF_00230388; iTF_00982388; iTF_00221365; iTF_01419733; iTF_00215126; iTF_00217174; iTF_00217848; iTF_00983064; iTF_00220153; iTF_00231673; iTF_00214490; iTF_00225339; iTF_00231419; iTF_00219900; iTF_01418685; iTF_00223550; iTF_00218527; iTF_00218783; iTF_00226271; iTF_00216064; iTF_00223296; iTF_00226016; iTF_01421024; iTF_01070019; iTF_01069771; iTF_01066618; iTF_01066363; iTF_01539971; iTF_00676372; iTF_00676125; iTF_01539711; iTF_01068648; iTF_01069322; iTF_01070732; iTF_01068397; iTF_01069075; iTF_01070464; iTF_00685103; iTF_00684875; iTF_00140945; iTF_00140689; iTF_00761074; iTF_00761297; iTF_01067959; iTF_01067713; iTF_00118109; iTF_00118358; iTF_01065917; iTF_01065674; iTF_01067040; iTF_01067282; iTF_00228775; iTF_00229031; iTF_00303210; iTF_00303474; iTF_00360584; iTF_00361004; iTF_00360313; iTF_00361280;
80% Identity
iTF_01424716;