Basic Information

Gene Symbol
RREB1
Assembly
GCA_011636605.1
Location
VBVP01002007.1:2637-21845[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 1.2e-05 0.0017 19.3 0.7 1 23 41 63 41 63 0.97
2 15 0.00014 0.019 16.0 0.1 1 23 77 99 77 99 0.98
3 15 4.7e-05 0.0064 17.4 4.2 1 21 105 125 105 128 0.95
4 15 0.0061 0.84 10.8 0.0 3 23 225 246 223 246 0.96
5 15 0.0047 0.64 11.1 3.7 2 23 252 274 252 274 0.96
6 15 0.15 20 6.5 0.2 1 23 501 523 501 523 0.96
7 15 4.7e-05 0.0064 17.4 0.3 1 23 532 554 532 554 0.98
8 15 0.0035 0.47 11.6 3.1 1 23 560 583 560 583 0.96
9 15 0.00039 0.053 14.5 3.1 1 23 954 977 954 977 0.97
10 15 0.00058 0.078 14.0 0.1 2 23 1246 1267 1245 1267 0.97
11 15 1.7 2.4e+02 3.1 11.1 1 23 1273 1296 1273 1296 0.97
12 15 0.036 4.9 8.4 3.2 1 23 1340 1364 1340 1364 0.96
13 15 2.5 3.4e+02 2.6 2.1 1 23 1444 1467 1444 1467 0.95
14 15 0.0092 1.2 10.2 0.4 2 23 1520 1541 1519 1541 0.94
15 15 0.0022 0.29 12.2 5.2 1 23 1547 1569 1547 1569 0.98

Sequence Information

Coding Sequence
ATGGATTACTCGAAGAAAGTGACTGGATCCAAGAATGGACCCGATCAGGAACAGGAAAACGAAACGCAAATTGATGCTGCATCGCCATCATCAAGCGTTGAATTGTCGGAGAATGGCACGCATCCATGCCCGACGTGTCCAGCGGTATTTTCCAGTTCCCACGAACTGACGAATCATCTGCGCGGCCATAATTCACCTCGCAGCACGGACTGCAGCGGCGAGGAGGACTACAGCTGCGGCGTATGCAATAAGGTGCTCAGCTCGGCGAGCTCGCTGGACCGGCACGTGCTGGTGCATTCGGGCGAGCGGCCGTTCAAGTGCAAGTACTGCGACATGTCGTTCACGACGAACGGCAACATGAACCGACACGTGAGGTGCACCCATCGGATGGTGTCGCCGAACAGCTGCACAGATTCCGAGGGCAGCAGCGGCTCGGAGAGACCGGCAGCGACGAGCCAGGATGAGTATAACAACAACGAGATAGCCACGCGCAACTCGCCAGACCTGATCGACGATCAGCTACCGTCGCCCAGCGGCAATCGTGCGAACAAGCGGAAGTGCCCGGACGAGGACATCAGCGACATGGAGGAGCAAAGGAGGCACAAGATTCTCCTGAACAACACCAAGATGACGATCAGGTGTCGGCCGGAGGACGAGCTGAAGACCTTCGGCTGTCCGATCTGCGGTCAGGACTTTGCGAGCAGCGCGATTCTCGAGTCCCATATGGAGCGCGTGCACCCAGGCTCCCCGGCAACGTGCGAGACCTGCAACCAATCGTTCAAGAATCATCGCGCGCTGAACCTTCATCGTTCGATGAGACATTACAAGAAGAATCCAGAGGGTAGCAACAGCCGTAGCCTGCGCAACACCGTGGACGGTTTCAGGGATCTGACGTTCATCGACTTCTCGTCCATCAAGTTCCCGACGATCGCTCGGGCGATGTGCGAGCGCGAGCTGCACCGGCCGGCCTCCGGCGAAGCCAACAGATTCCAGTGTATGAAGTGCTTGCACGCGTTCCCCTGCAGACAAGCCCAGCTGGCCCACGAGAAGGAATGCAAAGGCCCCTACAAGAACAAGAGAAACAGCAACGACAACAACAATAACAACGACATCAGTACCAACAACAATCTCGAAACGGAGCTGGATGACCCGAGTCCGCAGCCCGACGATCCCAAGACGAAGCGCGAGATCTTCTTCGCTGTGCTGGATCTGCAGAACAAGTCCTTGGCGCACGAGATGAAGGAGCCGCGGGAATCGAGCGAGATCAAGGAGCCAAAGGAGACTAAAGATCTAGCGGATATCCCGAGCATCCTGTCTGTCAGTCTAAACGGACTGCAGACCTTTCCTCGGTCGGACGCGAGTACGCCCGAGAACAACATCAAGTTCAACCCGAACGTTAGCTCTTCAGGTTCCTCGGGCACCTGTTCGTCCGAGTACAACGAAGAGGAGGCGCAGGACGCTTTCACTGCGGAATTTCGGAAAATGAAGCTGAAGGGCGAGTTCCCTTGTAGATTGTGCACATCCGTGTTCCCCAATTTGCGGGCGCTGAAGGGGCACAATCGCGCGCATATGAACGTAGAACCAGGTATGTCGTATCCGTGCAATATGTGTCCGTTCACCAGCACTGATAAGGGCGCTCTGATGAAGCACCTGCGATCGCACAACGGCGATCGTCCGTTTGAGTGCTCTCTTTGCAATTATGCGTTCACCACCAAAGCAAATTGCGAGAGGCACGTAAAGAATCGTCACGGGATGATCAGCAAGGAGGACGTTAAGAACGCACTCATCTATCACCCGAGCGAGGACTCGACAAACGAAAACATCGAAAGGAGCTCGCCCAGAGTCGTCAGAGAAGATGTGCGGAAGACGCTTATTTATCCGAATGAACGCGAGGAGATTCCCCAACAACAGATACATTATCCGTCTATAGCGGTGGATTGTAACCCCGGACCGTCAAACGTCCGCGCCGAGATGCTGATGAATCGCTATGATAAATCAGACGCGTTCGCCAGAGTGAAGATGCAGGCTCTCAATCTCGTGAAAAAAAGCGCCGACGAAGTAGGCTTGTCGCACGATCTGATCGTGAAAGCTAATTATTCGAAgctcgacgacgacgtcgagtCGGGATCATCGGACGGCAGCGTGTCTCTAGTCAGTGATACCAAAACAGATACACACCAAAGAATTCAAGCTAGTCCGATCAACCTGACGAAGCCCTCGACGAGCTCCGGTTTGAGCTCGGCGGGGGAGGACGCTCCGTTGGACCTGTCCATGGATGTGTTGGATCTGAGCAGGAAGCGAAAAAGGGAAAGCGAGGATTCCAGCTTGCAGGAGGAGAAGCGGTTTAAGACCAATCAGCAGGAATTGTATGCCACAAACCCAGCGCTGCTGCTGACCCAGGCCTTACTGAACAGAGCGCGCGAGAGCTCGCCGACAACGTCGCTGGAGACGCTTTACGCGAATACTATCTACCGCAATTTTGGCACATTAACTAGTGCCGGTATGATACCGCCGTACTTTCTCGGTCCTCACATGTTCAGCCAGGAACTGGCCGCGAAGGGTAGACTGCAGAAGGAGCTGGTTAGAGGTTTGCAGTTGACCGGCGGTGGCACACTCTCGGTTGATCCGTCGCTGCCCAGCACTAGTTACACGGCGTATTCGCAATCGAGGGATACTCCGCAAACCTCGAACGAGCAGAATGCCTACGCGAACCTGATAAGCGCGCAAATGACCAACCAGGTCCCGCCGAGTCGCGAGAAGACGGACAGCATCTCGTCGAACGATCCCGTGAAGATGGTGCTCAAGAACGGAGTACTGATTCCCAAGCAAAAGCAGCGCAGATACCGAACCGAGAGGCCATTCACCTGCGAGCACTGCACGGCGAGATTCACGTTACGCAGCAACATGGAACGGCACATCAAGCAACAGCATCCGCAGTACTGGAGCCAAAGACCCCGTGGCGGACACTCGACCAGAGGCAGACCGCCCGCGAGTCATCCGACTATGGTACAGAATCCGTCAACGTCGCAGGTGGCACAGTCGTACTCGAGCATTCTCCCAAGCGTCGACACGCCGGGGATCACGTCAACGGACTACGGCACGCATCCCATCTCGGAGGAGGTGAAATACGCGATTCTGGCGCAACAGCTGAAGGCCAACAAAATGGATGACAATGATTCGGACGACGAGATGGTAATAGACGAGGAATCGGCCGATCGGGAGGCTCAGGAGCCGCAAGCTCTGCGCGAACCTGGCACAAGCTTACTGAGAGACCAGTTGGAGGGCAGCGAGAGTGTCAAAGACATTGTCATAAAGACGGAAACAGTCGAGTCCGCGGAGGAGACCTTGAAGGAAACTCCCGACGAGCAGACCGCACGAAGTAACATCGACAGCGTCAATTCGGAAGAATCCACGGCTGCCGAAGGCAAGTCAGTGCGCGCTGAAGAAACGACCGTGACCGAGTCCGCCGAGCGGGAGCAAGGCAAGCTCGAGGACGGAACGCCCGATCTCGCGAGCGTCTCGAAGCTCTTGGACAACGCGTCGCAGCAATATCAACAATTCCAGCCACAATACCTGAGTGATGAGGAGGGCCCTGTTGCGTCGACCAGCGGCAACAATTCCGGCAGCGAGAAGTCCGACTCCATGAACTCGTTGAACTCCGGGAACGACTCCCCGACGaccaagaagaagaagaagaaaaagaagtcgGCGTACTCGATGGCGCCGAACCGCGTCGTCTGTCCATACTGCGAGCGCCAGTTCCCGTGGACCTCGTCGCTGAGACGGCACATCCTCACCCACACCGGCCAGAAGCCGTATCAGTGCGTCCACTGCTCGCATCACTTCACCACCAAGTCCAATTGCGACCGCCACCTGCTGAGGAAGCATAAGGCGAAGGCGAACAAGATGCGCCGTGCCAGGAACTCATCCTCGCCCGACGTCCAGGTGGTcgccagcagcagcagcagcagcaacggcAGCAACACGTTCTCCATGAGGAACGTGCCCGAGAGGCCGTTCAAATGCCATCAGTGCCCGAGCTCGACGTTCGCCACGTTGGGTAACTTAAAGAAGCATCGGTCGAGCAAGCACCGCAAGAATGCGTCCAGATCGGAATCCAGCGATCAGCAGAACAGTCCGCCGCAATGTACCGCGCAGAACGACCAGAGCGATTACGAAAGTCGCTCGTCGAGCATGTCCGACAATATGGAGAACACGTCGCCCGCCGTCGCGGTCGCGAAACCGACTTCTAACGTGTCCCCCTCGATAAACGATGCCACTAGGTCGCGCAAATCGCCAAGACTGTCGCCGAGTCCCGGCGACGTACCTTTCAAGTGTTACCTGTGCGACAGTGGTTTTTCGGAACGCCAGGATTGCTTGGATCACATTAAGATGAATCACAAGCGCTCGTATGAGATGCTGAAGGCCAAGGGCGCCCTCGATATGGCATCCATGAACATAGACGCGACCGAAGATCAGATATTAGCGTCGCAGCAGCATCACAGCGACGGAGAGGAGAAGAAGGGCCGTTTTCCCGACTACAGCAACAGAAAGGTTGTGTGCGCTTTCTGCATGAGACGATTTTGGTCCGCGGAGGATCTCCGGCGTCACATGAGGACCCACACGGGCGAGAGGCCGTTCGAATGCGACATCTGCACCAGGAAGTTCACGCTCAAGCACAGCATGCTGCGTCATCGCAAGAAGCACGAGTCGGTGGAGTCCGTCATGTATGTAGGCAACAGCGGCGACGAAGAGAACTCGCCCGCGCAGCTGCCGACGATAACCCCCAGGAGCCAGCAGCACTCGCCGATCTCCACCAACACCAGCAGGCCCCGTACCCAAGATAGAATCTCCCTGCCGACCGTCGCGGCGGTCGCAACGGCGGACGCGGCACCCTGCGCCCTGATGCGGTACAATCACTACGATAACATGGCCACCCTCACCGGCAGAATGGCAAACGACGGTCCTCAGGGCGCCGCTCCAGCCCCCTTGCCTTCTCCCCCGCCCCCCGCCGAAGTACCCAGCGAGGACAACGACCTGATCTCCAATTTGCTGGGGATACGCGAGAAAGGTTTGCTCGACAAGGTCCTTCTGAGCTCGGCGGACGACGCGGCGAAGTTGTTGGGAGTCAATCACAGCGAGTGA
Protein Sequence
MDYSKKVTGSKNGPDQEQENETQIDAASPSSSVELSENGTHPCPTCPAVFSSSHELTNHLRGHNSPRSTDCSGEEDYSCGVCNKVLSSASSLDRHVLVHSGERPFKCKYCDMSFTTNGNMNRHVRCTHRMVSPNSCTDSEGSSGSERPAATSQDEYNNNEIATRNSPDLIDDQLPSPSGNRANKRKCPDEDISDMEEQRRHKILLNNTKMTIRCRPEDELKTFGCPICGQDFASSAILESHMERVHPGSPATCETCNQSFKNHRALNLHRSMRHYKKNPEGSNSRSLRNTVDGFRDLTFIDFSSIKFPTIARAMCERELHRPASGEANRFQCMKCLHAFPCRQAQLAHEKECKGPYKNKRNSNDNNNNNDISTNNNLETELDDPSPQPDDPKTKREIFFAVLDLQNKSLAHEMKEPRESSEIKEPKETKDLADIPSILSVSLNGLQTFPRSDASTPENNIKFNPNVSSSGSSGTCSSEYNEEEAQDAFTAEFRKMKLKGEFPCRLCTSVFPNLRALKGHNRAHMNVEPGMSYPCNMCPFTSTDKGALMKHLRSHNGDRPFECSLCNYAFTTKANCERHVKNRHGMISKEDVKNALIYHPSEDSTNENIERSSPRVVREDVRKTLIYPNEREEIPQQQIHYPSIAVDCNPGPSNVRAEMLMNRYDKSDAFARVKMQALNLVKKSADEVGLSHDLIVKANYSKLDDDVESGSSDGSVSLVSDTKTDTHQRIQASPINLTKPSTSSGLSSAGEDAPLDLSMDVLDLSRKRKRESEDSSLQEEKRFKTNQQELYATNPALLLTQALLNRARESSPTTSLETLYANTIYRNFGTLTSAGMIPPYFLGPHMFSQELAAKGRLQKELVRGLQLTGGGTLSVDPSLPSTSYTAYSQSRDTPQTSNEQNAYANLISAQMTNQVPPSREKTDSISSNDPVKMVLKNGVLIPKQKQRRYRTERPFTCEHCTARFTLRSNMERHIKQQHPQYWSQRPRGGHSTRGRPPASHPTMVQNPSTSQVAQSYSSILPSVDTPGITSTDYGTHPISEEVKYAILAQQLKANKMDDNDSDDEMVIDEESADREAQEPQALREPGTSLLRDQLEGSESVKDIVIKTETVESAEETLKETPDEQTARSNIDSVNSEESTAAEGKSVRAEETTVTESAEREQGKLEDGTPDLASVSKLLDNASQQYQQFQPQYLSDEEGPVASTSGNNSGSEKSDSMNSLNSGNDSPTTKKKKKKKKSAYSMAPNRVVCPYCERQFPWTSSLRRHILTHTGQKPYQCVHCSHHFTTKSNCDRHLLRKHKAKANKMRRARNSSSPDVQVVASSSSSSNGSNTFSMRNVPERPFKCHQCPSSTFATLGNLKKHRSSKHRKNASRSESSDQQNSPPQCTAQNDQSDYESRSSSMSDNMENTSPAVAVAKPTSNVSPSINDATRSRKSPRLSPSPGDVPFKCYLCDSGFSERQDCLDHIKMNHKRSYEMLKAKGALDMASMNIDATEDQILASQQHHSDGEEKKGRFPDYSNRKVVCAFCMRRFWSAEDLRRHMRTHTGERPFECDICTRKFTLKHSMLRHRKKHESVESVMYVGNSGDEENSPAQLPTITPRSQQHSPISTNTSRPRTQDRISLPTVAAVATADAAPCALMRYNHYDNMATLTGRMANDGPQGAAPAPLPSPPPPAEVPSEDNDLISNLLGIREKGLLDKVLLSSADDAAKLLGVNHSE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01016049;
90% Identity
iTF_01355659;
80% Identity
-