Basic Information

Gene Symbol
-
Assembly
GCA_011636605.1
Location
VBVP01004622.1:1290-11860[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 32 6.4e-06 0.00087 20.2 1.0 1 23 244 266 244 266 0.98
2 32 0.0092 1.3 10.2 3.7 1 23 289 312 289 312 0.96
3 32 0.00062 0.085 13.9 0.5 2 23 319 341 318 341 0.96
4 32 0.03 4.1 8.6 0.1 1 21 361 381 361 382 0.95
5 32 0.0032 0.44 11.7 0.2 2 23 480 501 479 501 0.95
6 32 0.0064 0.87 10.7 0.5 2 23 508 530 507 530 0.91
7 32 0.00019 0.026 15.5 0.2 1 23 602 625 602 625 0.96
8 32 0.051 7 7.9 2.5 1 23 631 654 631 654 0.95
9 32 0.12 17 6.7 1.5 1 23 667 689 667 689 0.97
10 32 3.5e-05 0.0048 17.8 0.9 3 23 734 755 733 755 0.96
11 32 3 4.1e+02 2.3 0.4 1 23 787 810 787 810 0.92
12 32 0.0048 0.65 11.1 0.8 2 23 817 840 816 840 0.94
13 32 0.92 1.3e+02 3.9 0.0 2 23 849 871 849 871 0.90
14 32 0.026 3.6 8.8 0.0 2 23 878 900 877 900 0.93
15 32 9.1e-05 0.012 16.5 3.2 1 23 908 930 908 930 0.97
16 32 0.019 2.6 9.3 0.8 2 23 966 989 965 989 0.94
17 32 0.00021 0.029 15.4 3.3 1 23 992 1015 992 1015 0.97
18 32 0.0007 0.096 13.7 0.1 2 23 1022 1044 1021 1044 0.95
19 32 0.00093 0.13 13.4 3.9 1 21 1071 1091 1071 1092 0.95
20 32 0.0028 0.37 11.9 1.8 2 23 1106 1127 1105 1128 0.93
21 32 0.37 50 5.2 1.1 1 23 1131 1154 1131 1154 0.94
22 32 0.027 3.7 8.8 2.1 2 23 1161 1184 1160 1184 0.90
23 32 3.1 4.2e+02 2.3 0.2 2 23 1192 1214 1192 1214 0.94
24 32 1.4 1.9e+02 3.3 0.0 2 23 1221 1243 1220 1243 0.91
25 32 0.23 31 5.8 2.7 2 23 1252 1274 1252 1274 0.96
26 32 1.2 1.6e+02 3.6 0.4 2 23 1280 1302 1279 1302 0.91
27 32 0.017 2.3 9.4 0.1 1 23 1364 1387 1364 1387 0.95
28 32 0.00026 0.036 15.1 1.3 1 21 1414 1434 1414 1435 0.95
29 32 0.33 45 5.3 1.9 2 23 1536 1558 1535 1558 0.94
30 32 0.94 1.3e+02 3.9 0.4 2 23 1565 1587 1564 1587 0.94
31 32 0.71 97 4.3 2.5 1 23 1598 1620 1598 1620 0.97
32 32 0.017 2.3 9.4 0.2 1 19 1624 1642 1624 1645 0.94

Sequence Information

Coding Sequence
ATGGCGACGACGTCGACATCGTCATCGACGGCGACAGCAATGGCGACGGAGCCGAGAAAATCTTACGACGAGCTATGTCGCCTGTGTGCCTCCTACGACGCCGTCAGGATGCACATTTTCGGCCAGGAAGGCAAGAATCGTCAGCTCGTCGACAAGATCCAGACGTGCTTGCCGTTCAAGATAATGGAAGATGATTGTTTGCCAAAAGTCCTGTGTTATCGATGCATGTACAACTTGGAAAATTTCTATGACTTTAGGACTGCGTGTGTTAATGCAGCTGCTTGGTTGGAAAGAAATAGGCCGAAGGAAGGCGCGAGCGATGACGGCGCAAATGACAGCGCACAAACCGGCGAGGTGCATGCGGAGCTTCTtaaaggaaaggaaaatatGCCAGTACTTATTCCGGAAGCACCCATAGTCAATCCTAATGCAGCATTAGGTACACCCCCGAGATTAAATTCGGACGGTGAAGCAGATCCCGAGATCGAGGAGATTCTCGACACAAGTGAAGGTACGGATGAAGCTACAGTAATCGACGATTCGGAAGATCGACGATCGGAATATGAGATGGCATATGAGATGGACATGGAGACGAATCCTAGCGACTTTTTGGAAATGACTCCAATGGTAACTGAGGAAAATGAAGAGGAGTGCGGTATGAACAACACGAGCGCCGCGACCACTCAAGATACCGCGGTCTTTTCACATACATCGCAACAACATGAAGTCTACGTCTGTTCTCTCTGCAACAAAGCATTCAGTTCCAAAGGTCACTTATCCCTGCACGCGAGAATTCACGTGGGTGAGGGTGATGTGATTGGCGAAAGAGTAATCACCGACGACCATACTTCGTACCAACGACCGTATCAATGTGATCTTTGTCATAAATCGTATTCCACTGCGAAACACCGCTGGGGACACGTTTCTACGACACATCGGGGACATCCTGCAGTAACGTGTGCATATTGTTCTCGTATATACTCGACGCGATATAATCTCGATGAGCATATAAAATCGCGACACGCTGGTCTACCGCCACCTCCAGAATTATCGGTTCCTCTTTCACGCACCGAAACTCGTTATCAGTGCCAAACATGTCTGATGGTGTATACGGATCTAGCAGATTTCACGGCGCATCGGCAGATATGCATCCAGGAGCAACGTACAGATCTATTGGGGCAAACTGAAGCGCAAAGCAGTAAGATTTTCGCCGACACGTCCGATATCTCGAGCATAGAGTCGGATGACGAAAACAAAGACTTCAAGAACGCCGAGGCTAAATTGGCGAAAAATCCACAATTAACTATATTGAAACAAGCGCTGACTAAAGGAGACAGtttaaaacgaaattttgACGATGATGGCTCGACATCCAGCGGCAAGccgaaaaaaatagttaagtcagAAGAGGGCGAGACGAATCCTCAGAAGAGATGGTATTGTGAATCTTGTCCACAAAGTTTTACATCGGTGGATAGTTTGAAGGAACATGAGATTAGGCATGATGCCGAAAAGccatttatttgcatattgtgCAAGAAAGATTTTGTTTTGAAATCTTCATTAATTAGGCACATTACAACATCACATGGCGTTGATCCTACTCCTATCGTTGACAGTGAAAAGTATCTAAAGGCAACAGTAATGCCTCAGAATTGGAACGATCGAGTGGACACGGTTTACGAGCACATTGAGATAAAGGAACCACCGGAGCTTTCACCGTCACCTGAgataaatttagaaaatgatgACAAAGATTACAAGAATATAGAAATCCACGAGAATATAGAAATTGAAACGGTATTTGTATGTGAGACTTGTAAGAGAGATTTCAATGACCGAGCGTCATTATGGCTACATATACGAGCGATGCATAAAGAATATGCAGCATTTACTTGTGGAGTGTGTTTAAAGATGTGCTTTGATAATACGCAACTTCAAAATCATGTCTACATGTATCACGGAAAATCTAAGCTTTTAATATCGGAACAAAGAAGGTACAGTTGTACGATCTGCGGTAGACAGCATGACTCGAGGAAGAAGCTAATCACTCATGTCTCGATACATAATGTCGATCCTGCCTATGATCCTGCGAGttttgtacaattaaatagtaattattacaatgaaaacTTGAATGGGAATGAAGGAAATGAACAAGTATTAGATTTTGACGGAGAAGATGGTGAGAAGGTCGATTGTTACATTTGTTACAAATCTTTTCCGACTGAGGACCATCTGATACGACATCAGAGAAATGCTCATAAGTCTGACCAGATAGTTTCATTAGATGCTACGGGTAGTGGCAATACTCTTAGTGTCAATGGTAATGGTAATAGAGCGCAGTATCATTTATTCTTTGTTTGCGAGGTATGTGGCAGTTCACATTCGAGTAAATGGGAACGCTGGTTGCATATCAACAATACACACAACAACGAATCTTCTATTAAATGCGAATGGGAGAATTGCGGAAAGATATTCGCGACGAAATCGTTGCGCAATGAGCATCTTCAGCATCACGCGGTACAAGGACCCTCGCCGAATACCTGCGAGATATGTGGAAAATTGTGGCCTACTCGCGTCGATTATTGGAAACACGTGATGGGCGTGCACGCGGACACAGTGCCTCTGATTTGCGGCGTTTGTCTGAAAGTATTTTCCGACGTAATGCAATTGAGCGCACACGTGAAGGCGAAACATTGGCCGCTGACCAGTGGTGATTTCTGTTGTGATATCTGCGGTAGACCCTACTCCAACAAGTCCAAGATGTCCCGGCATCGAAAGATCCATGGCTTGGAGGCTATGGACGCTGTATGCGATAATAGCAGTTTCAATGAAACGACTAATGAATCGGTCAAACCTGATCACAACAATGGCGCGTCGGAAATAGAATTGAGTTGCGACCAGTGCCCGGAACTCAGCTTCACCACCCTGGACAGCTTGTGTAATCATCGACGGATAGCACACAATCTTTTCCCGTGCGACTTGTGCAACAAATGTTACGGCAGAACATCGCACTTGTGGAAGCATGTGAATAGGGTGCACAAGGGACACGCGGATGTGACCTGTCCCTACTGCGCCAAGACAAGTGCGTCAAGGGATCACCTGGCAGCGCATATCGCCAAGATTCATAGGTACCTGCCAGCAATGGGTAAGGATAATCAGAACTGTGTCGCTTCCAAGTCGCTAAGTGTCGAGGACGATGTCTTGCATTATTGCGAGAAATGTAACAAGGGATTCCACAAGCGCTACTTGCTCCGTCGTCACATGAAAGGTTGTCAAAACTACCGTAAAGATCCTGGTGCGTTGTTGACTCGTTGCCGGGCCTGCGAGAGGATATTCAAGGATCGTGCGAGCCTGCAGAAGCACATTGAGAATCATCATAGCACGTATACTTGCCACTTGTGTAACGAAACGATCACTTCCAAGCTAGGTATCATGACACACAACCGCGTCAATCATATGGATCATCCGGACTTGACGTGCGACCATCCAAGTTGTAAAAAACTTTTCCGTACTAAAGAAGATTTGGAATCTCATCGAAAGGATCACAAGTATCATAGCAACCCGAACGTTTGTGACTTCTGCGGTGACACTGTGGAAAATAAACTGAAACTGAAGATGCACGTATTATCGTTGCATCGTAACGAGATCGGCGTTTCCTGCGGTGTCTGCCTCATTCCCATGAAGGACCCCAAAGACTTGAAGAAGCACGTCGAGTCGGAGCACAGCAGCGTTCTTTCCAATCCAAACACGTGTCAGGTGTGCGGCAAGCAATATGCATCCAAGTGGAAGGCCTTTGATCACACGAAGAAATGTCACGGCAAGGTCTTCCTCACGTGCAAACAGTGTTTAGCGGTTTTCACGGATGAAAACGCGATACGCGATCATTACGAACACGTGCACAACGTTCCAAAGGATCAATTAGCCGTTTTCGAATATAGAATGGATATTGGTGCAAAGAGAGAAGGTTACGAGACTCCCGATATTATTGTCAAGGAGGAACCGGATGATATGGAATTCGACGAGGAGATATGTGACGAGAGTTCGAATGACTCTCGTAAACGTAGAAGATCGCCAAACGACACGTACGATTGCGAGATGTGTCCCGAGATCTTTCTCAATTCGGACACTCTCGCCAAGCATTATCAGAACGTCCATAACACCGACCCCGTCCGTATGTTCAAGAAATTCAAAAAGGATAGCGACAGCAAACGCAAGATGAgaaatagaaacaattttgAGTGTAAGAATTGCAAGAAGCAGTTCTCTACCAAAACCCTATTCTGGAATCACATCAATTTATGTACACGGCGAAACTCGATAGGTAGATTTGACATGCCGAATAATGTCCCGACGTCAATTCTGGAGTCCCATCTGAAAAACAATAATCAGATTCCACGAGAAGAACCGCTATCGCTGACGAACGACGCCAACTTGAACATTCCCGATTTCAATCTATTCGAAGACATTAATATGCAATTGTCGGCCCAGAAACCTGTGCCGAATCTTATGCCGTTGTCGCAGATGAAGGCGACGGGTAACGGCAAGTGCTCGAGAAAAGACTCGCGCAAGGTGTACGACGAGTCGACCAATACCGAGTGCACGTGCGAAGTCTGCGGTAAGCAATGGCCCGCCAAGAAACATTTGTGGCAACATCTGATTCGTTTCCATCGCGCCGAAGCTGCCGTTACGTGTGGCGTATGCTTGAAGTTATGTAAATCGTATCAAGATCTGGCCGACCACTTGAAGGCCGAGCATGCCCCTGTCTTGTCGCCAGAGGGCAACAATTTCACTTGTAAGACATGCGGTAGATACCACAACGCGAGAAGCAAATTGTTGTTGCACATGAGCATTCATATCGGGAACTTCCAGTGTCAAAAGTGCCAGCAGGGTTTCGCGAGCGAGGAGAAACTCAACGAGCACGCAACAAGCTGCAATGGTAAGGAATTTGATGATCACGCGGTGGCGGACGAAGATAATGTAAAGAATGATAACGACGAGAAGGGCAGCTTGATCGCCGACGAAACGTCGGTCATCGAGGAAGCCGAAGAAGCGGAGGAAGCGGATTTCGAGTCGGAAGGCGAAGAGAGTAGAGATATCCATGAAGACAATTCAGAAAATAGCGAAGGAGACAATTCGGAAAATAGCGATGATTCGGATAGCGACAGTAATAGCAGTTCGAGCGAGGATGAGAAcgaagaaggagaggaagaggaagaggaaaatgaaaatgaaaatgaaaatgaaaatgaaaatgaaaatgaaaatgaaaatgaaaacgaAAACGAAAATGACAACGAAAATGAGTCTGATACAAGAACCACTAGTAGAGAGACCGGTGATAGTGTGTCGTGTAATTCCgagagcgacgacgacgaatcGGATATGGATGAAACGGAAGTGACGGAAAAGAAAGCGGTACAATTGAGCGATATCGGTAGATTTAGAATACGCGGTGACGGTATTCAAGAGAATGTCAAGAGTCAGAAAACCGATCTTACGTCCGTTACCGCAGCGACAACGATTGCAGAACAAGCTAAACAAAGTAATTTGAATGATCTTTTGATTGCCACTGCATCTGCGAACATGGACAAATTTGAAGCATTTCGTCACGAGGAATCCGCCAAAGCTGCGGCGAGCGACGTAGACTTAtctgatgatgatgatgatgataatgaagACGATGGTGATAATGAAGAAGATGGTGAGGATGAGGATGAGGATGAGGATGAGGATGAAGGTGAAGGTGAAGGTGAAGGTGAAGGTGAAGGTGAAGATGAAGGTGAAGGTGAAGGTGAAGGTGAAGCTGAAGCTGAGGCTGAGGCTGAGGCTGAGGCTGAGGCTGAGTCTGAATCTGAGTCTGAAGCTGAGTTTGAGGCTGACCCTGAGCCTGAGGCTGAGGTTGAGGCTGAGCCTGAGGCTGAGGCTGAGGCTGAGGCTGAGGCTGAGGCTGAGGCTGAGGCTGAGGCTGAAAGTGAGAATGACAATGAGGATGAGGATGAGGATGAGGGTGAAgccgaggaagaggaggaggaagaagaagatgatgaagatgatgatgatgaagaCGATGATGATGGACCGCCTGTTTTAAGTCCAATAATGCCTTTGTTACCGGAAAACGAATCTGAAGAACACAGCGGCACGACGGATCGCACGAGACACAAGCTCAGTCCGATGGTTTCTCTAAGTATGACTAAAGATCTGGAGGAATGCGAAATGCCAAATGACGTAGAGAACGTGTCGAACGCCAATCTTTTCGCGGCTAACAACAATGATTTGCCCGTAACATGGGACGAGAACTTGGATGACAACGGAATCGACAATGGCGATTGCAACTCCGACATGGAAGACAGGGATGTGGAGAAAAACGAAGAGTTTAGTAAGGAGTACAAGATAGAAGTGAACGAGGGTGATGACTTTGAAGAGGATTCCGCGTATGAGAACGTAGTGGATAATAGTAGAGATGGTGATGGGGACAATCAAGTGCACGAGGTGCATAATCTGGACGGTACTGTGTTAATGGTGGCTAATGACGCGGAAGGTAATCACATTTTGATAGAACAGAATGTGTTAGATATCGATAATGAGGACTCTAATGCCGAAGCGGCGCAGTATATTTATCCAGAGACCGCTTACGAAATCGAGGAAGAGGATTACGCGACGCGAAACGAAAGCGACATTATGCAAACGGATGAGGTGCAAGGTATGTCCTATGTTCAAGATACATCGGAGAATGAGGATAGTACGGAGGGTGACGTCGAGGAGAACAGTAGTGACATGCAGCAACAGTAG
Protein Sequence
MATTSTSSSTATAMATEPRKSYDELCRLCASYDAVRMHIFGQEGKNRQLVDKIQTCLPFKIMEDDCLPKVLCYRCMYNLENFYDFRTACVNAAAWLERNRPKEGASDDGANDSAQTGEVHAELLKGKENMPVLIPEAPIVNPNAALGTPPRLNSDGEADPEIEEILDTSEGTDEATVIDDSEDRRSEYEMAYEMDMETNPSDFLEMTPMVTEENEEECGMNNTSAATTQDTAVFSHTSQQHEVYVCSLCNKAFSSKGHLSLHARIHVGEGDVIGERVITDDHTSYQRPYQCDLCHKSYSTAKHRWGHVSTTHRGHPAVTCAYCSRIYSTRYNLDEHIKSRHAGLPPPPELSVPLSRTETRYQCQTCLMVYTDLADFTAHRQICIQEQRTDLLGQTEAQSSKIFADTSDISSIESDDENKDFKNAEAKLAKNPQLTILKQALTKGDSLKRNFDDDGSTSSGKPKKIVKSEEGETNPQKRWYCESCPQSFTSVDSLKEHEIRHDAEKPFICILCKKDFVLKSSLIRHITTSHGVDPTPIVDSEKYLKATVMPQNWNDRVDTVYEHIEIKEPPELSPSPEINLENDDKDYKNIEIHENIEIETVFVCETCKRDFNDRASLWLHIRAMHKEYAAFTCGVCLKMCFDNTQLQNHVYMYHGKSKLLISEQRRYSCTICGRQHDSRKKLITHVSIHNVDPAYDPASFVQLNSNYYNENLNGNEGNEQVLDFDGEDGEKVDCYICYKSFPTEDHLIRHQRNAHKSDQIVSLDATGSGNTLSVNGNGNRAQYHLFFVCEVCGSSHSSKWERWLHINNTHNNESSIKCEWENCGKIFATKSLRNEHLQHHAVQGPSPNTCEICGKLWPTRVDYWKHVMGVHADTVPLICGVCLKVFSDVMQLSAHVKAKHWPLTSGDFCCDICGRPYSNKSKMSRHRKIHGLEAMDAVCDNSSFNETTNESVKPDHNNGASEIELSCDQCPELSFTTLDSLCNHRRIAHNLFPCDLCNKCYGRTSHLWKHVNRVHKGHADVTCPYCAKTSASRDHLAAHIAKIHRYLPAMGKDNQNCVASKSLSVEDDVLHYCEKCNKGFHKRYLLRRHMKGCQNYRKDPGALLTRCRACERIFKDRASLQKHIENHHSTYTCHLCNETITSKLGIMTHNRVNHMDHPDLTCDHPSCKKLFRTKEDLESHRKDHKYHSNPNVCDFCGDTVENKLKLKMHVLSLHRNEIGVSCGVCLIPMKDPKDLKKHVESEHSSVLSNPNTCQVCGKQYASKWKAFDHTKKCHGKVFLTCKQCLAVFTDENAIRDHYEHVHNVPKDQLAVFEYRMDIGAKREGYETPDIIVKEEPDDMEFDEEICDESSNDSRKRRRSPNDTYDCEMCPEIFLNSDTLAKHYQNVHNTDPVRMFKKFKKDSDSKRKMRNRNNFECKNCKKQFSTKTLFWNHINLCTRRNSIGRFDMPNNVPTSILESHLKNNNQIPREEPLSLTNDANLNIPDFNLFEDINMQLSAQKPVPNLMPLSQMKATGNGKCSRKDSRKVYDESTNTECTCEVCGKQWPAKKHLWQHLIRFHRAEAAVTCGVCLKLCKSYQDLADHLKAEHAPVLSPEGNNFTCKTCGRYHNARSKLLLHMSIHIGNFQCQKCQQGFASEEKLNEHATSCNGKEFDDHAVADEDNVKNDNDEKGSLIADETSVIEEAEEAEEADFESEGEESRDIHEDNSENSEGDNSENSDDSDSDSNSSSSEDENEEGEEEEEENENENENENENENENENENENENDNENESDTRTTSRETGDSVSCNSESDDDESDMDETEVTEKKAVQLSDIGRFRIRGDGIQENVKSQKTDLTSVTAATTIAEQAKQSNLNDLLIATASANMDKFEAFRHEESAKAAASDVDLSDDDDDDNEDDGDNEEDGEDEDEDEDEDEGEGEGEGEGEGEDEGEGEGEGEAEAEAEAEAEAEAESESESEAEFEADPEPEAEVEAEPEAEAEAEAEAEAEAEAEAESENDNEDEDEDEGEAEEEEEEEEDDEDDDDEDDDDGPPVLSPIMPLLPENESEEHSGTTDRTRHKLSPMVSLSMTKDLEECEMPNDVENVSNANLFAANNNDLPVTWDENLDDNGIDNGDCNSDMEDRDVEKNEEFSKEYKIEVNEGDDFEEDSAYENVVDNSRDGDGDNQVHEVHNLDGTVLMVANDAEGNHILIEQNVLDIDNEDSNAEAAQYIYPETAYEIEEEDYATRNESDIMQTDEVQGMSYVQDTSENEDSTEGDVEENSSDMQQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01355612;
90% Identity
iTF_01423087;
80% Identity
-