Tang001886.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tetragonisca angustula
Gene Symbol
btbd6b
Assembly
GCA_036937485.2
Location
JAWNGG010000012.1:1867482-1873084[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.7e-07 8e-05 23.2 0.0 26 109 98 184 75 185 0.87

Sequence Information

Coding Sequence
ATGACAGTCACACACAACAATGGCGACAGCTCACGATGCGCTCGCACCGAGCCTGAAAGGGCACGACAAAAGGTTCGGGAGGGTGTACGGAATCGAATTTACTCGAGGACCATAATCCTGCCGGTAATAGCGCGGAACTCGTCGAAAGAGCACGCGATCCTTCGAAACTCCACGGAAGATATGTCTCAAGTTCCTCTTATCGCCACCGAGGAGAACACGATGGAATCCTCCATTTGTAACATGGTGATTCTCGagGCTGGTTTACCTGGAGACACGTGGAGGTACTGCGTAGAAAGGGAACAACTGGCTGAAAGGTCGGAATGGTTCCGTGCGATGCTCGTGGGCCCTTTAGCACCTGCACCAAGCGATCCTCCACCCGTGCTGAAACTGCAACACATAGAGAAAAGAGCTTTCGATTATTTGCTCAGATACGTTCTCGACGAGCcgatcaattttcaatctgTGACTACAGCTCGTGCAACCCTCGACGCGGCTCATCAGTATCTCTGTCCAGAATTGGCAAGGCTCGCCGTTGAATACCTCGAAAGGAATTTGAACTCGAACACCGTGCTTGAAATCTACCAGGGCCTCAGTCTTTACGCGAACTATGTAACTTCCGCTTTCAACTCACCCACGGCTCCTCCGGCTCCTGGTGACGATGCTGGCGAAATAGCCGCAGTCTGCACGCGACTTCTCCTGACTTGCCTGGACGTGATCGACTCGGAACCGGAGGCGATTTTCAGCCAGGAATACTTTGAAGAGTTGAGCTGCGCCGAGGTGGAAGAACTGGCGTGCCGTGACACTCTGAGGTTGAACAACGAGTCGATATTGTTCCACGCGTTGGACAGGTGGGCCGCGTCCAAGTGCAGAAGAAACGGAGTCGAGCCATCAGCCAGCAACAAGAGATCCGCACTTTCGGACGATGTTTGGTACAGTGTTCGATATTCCCTCATGACTGACAGAGAGTTCATCGAGGGACCTATGGCGAGTGGGATCCTATCTAGCGAGGAGTCGGCTTACATCGTTGCTAGAATTCTGGGGCATCAGAAAGGAGAGGAGGTTCGTAGTTCGGTAAATGGACCATTGCCTAGACTAACCAATAATCCAAGGATCGATGTGAGAATGTACGAGGACCAAAGCTGCAGAATGTCGAAATCAGGGAAGAAAGAGTGCCAGGACAATCGGaagaacagaagaaaagaatgcGTGAATCAGGGACAGAGGACCTGCGCGAGAATCGGCAACTGTCTCGTGCGAGTTCTCGCCTGTATTTTCGACTGA
Protein Sequence
MTVTHNNGDSSRCARTEPERARQKVREGVRNRIYSRTIILPVIARNSSKEHAILRNSTEDMSQVPLIATEENTMESSICNMVILEAGLPGDTWRYCVEREQLAERSEWFRAMLVGPLAPAPSDPPPVLKLQHIEKRAFDYLLRYVLDEPINFQSVTTARATLDAAHQYLCPELARLAVEYLERNLNSNTVLEIYQGLSLYANYVTSAFNSPTAPPAPGDDAGEIAAVCTRLLLTCLDVIDSEPEAIFSQEYFEELSCAEVEELACRDTLRLNNESILFHALDRWAASKCRRNGVEPSASNKRSALSDDVWYSVRYSLMTDREFIEGPMASGILSSEESAYIVARILGHQKGEEVRSSVNGPLPRLTNNPRIDVRMYEDQSCRMSKSGKKECQDNRKNRRKECVNQGQRTCARIGNCLVRVLACIFD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00734066; iTF_01420387; iTF_01418467; iTF_01419118; iTF_01419760; iTF_00873918; iTF_00140717; iTF_00142579; iTF_00141333; iTF_01539735; iTF_00141950; iTF_00676147; iTF_00983711;
90% Identity
iTF_01420387; iTF_01418467; iTF_01419118; iTF_01419760; iTF_00873918;
80% Identity
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