Basic Information

Gene Symbol
-
Assembly
GCA_958299015.1
Location
OY282643.1:112578151-112586350[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0011 0.19 13.6 0.2 1 23 115 138 115 138 0.95
2 13 0.00018 0.03 16.1 2.2 1 23 143 165 143 166 0.95
3 13 3.4e-06 0.00057 21.6 3.9 2 23 176 198 175 198 0.96
4 13 5.8e-05 0.0097 17.7 8.7 2 23 375 396 374 396 0.98
5 13 0.00033 0.055 15.3 7.3 1 23 402 425 402 425 0.95
6 13 4.5e-05 0.0074 18.0 0.4 1 23 430 453 430 453 0.95
7 13 0.00021 0.034 16.0 6.7 1 23 463 485 463 485 0.98
8 13 0.00069 0.12 14.3 1.1 1 23 490 512 490 512 0.98
9 13 8.9e-08 1.5e-05 26.5 0.4 1 23 518 540 518 540 0.96
10 13 6.9e-07 0.00011 23.7 0.5 1 23 546 568 546 568 0.98
11 13 1e-06 0.00017 23.2 1.7 3 23 576 596 575 596 0.99
12 13 4.6e-07 7.7e-05 24.3 2.4 1 23 602 624 602 624 0.99
13 13 0.0038 0.64 12.0 0.6 1 23 629 652 629 652 0.95

Sequence Information

Coding Sequence
ATGAAAACCGATACTAATTTAGATATGGAACGGATTTGTCGTGTGTGTCTGAAGGGAAACATAGATCTCTATTTGCTATTTGATGAAAATTATGCCCTGAATGGAATTTCCTTACCACAAATATTGACTGAATGTACTATTTATAAGGTGCAGCGGCATGATGAGCTGCCACATCAGATCTGCAGCAGCTGCATGGAAGCGGCAAAGAATGCCTACAGTTTCAAGAAACGCACAGAGCAATCCTATCGCCAGTTAGTTGGGCTTTTAGAAAGTGTTAGCCAAGAACAATTGCTGACTggacaaaaatttgaacagtCAACACAAACCGATAAACTATCCATATATCCATGCGAAATGTGTGATGCAAAATTCTTTGAACCAGAAGATCTACGCAATCATCGTCTTAATTCACACAAGGGCACAAACTTTAAATGCAAAGTATGCGGTCAGAAATTTGCTCGTTTGTATCGTCTCAGAGGTCATATTTCGCTGCATCATCCCGAAGAAGGCTTAACACACGATACTAAGTGCACAGTGTGCGGAAAGCAATTTTCACGTAAAGATCATATGAGGCGTCATTTGAAAAATGTGCATGGAAAGCAAGTACCGACTGTCGAAAGATGCAACAAATCCACTTTAGAGGAACCGGAAATAAACCTAAAGCATGAATTAGACGCTAATCAGCTAACGGAAGGCGTATTGAACGATTCATGCCTTACGAAAAACGAAGCCATCTGGGATAATTATTCCACAAGAGAATCAGATAGCGATGATGACTTCAATGCTACAAATCCCATATCAAGTGACTCTCctgatgatgaaaatgatgagGAAGATGAGAAGCCTTTGAGTCTATTAAATCCAGTCAAACCGGTTTTGAAGGTTGAACCTGCCGATGATGAAATTTGCGCTGAACTAACAACCATAACAGAGCCTATCATattgaagtttgaacaagatgGTGATGGATTTGCCAAGATCTGTGAAAGCACACATGTTGAAGATGCACAAGCAGCTGTGGAAAATGTGAAATTGTCACCAAAGAAAACTACCATTATACGTGAATATCTTGGTGACAAACCAAGTGGTCGTCGGCGTACTTACGTTAAAGATAAAGACAATAAATGCTCTGAATGTCAGCGTGTTTTCTCACGTCACTGTCATCTACAGCGACATATGCTAACGCATACTATGGAAAAACCACATGAATGTACACATTGTTTAAAGCGTTTTACACGCCGTGATCACTTGAAGAATCACGTTGAAAGTCAGCATGGCGACAAGAACTATAAATGCGATCAATGTGATAGCGCATTTCCGCGCAAAGACGCACTGGAACGCCACAAAGCCTCCAAACACAGTGATGGACCAAACCTCAATAAAGTACACAAATGTGAATTCTGTGAGAAATCATTTGTCAGCAAAAACTATTTGCGTAAACATCATCTCATGCACACAGATCGCATTTTTAGTTGTAAGCTTTGCGATGATACCTTTAAAGAGCGTGCTCAATTGAGAGAGCATGAGAAAACACACAATGCTGCgcgcaattatttatgctctATTTGTGGCGAAAGCTTTGCACGCAATGACTATTTGCGTGTACATATGCGCAGGCATACTGGTGAGAAACCATACAAGTGTCAATATTGTGACAAAGGTTTTCCTCGTGCTACTGATTTGAATGTTCATGTGCGTTATCACACAGGCCACAAACCGAATCTCTGTACACTTTGTGGTAAAGGCTTCCATCGTGCCTATAATCTTACCATACACATGCGTACACATACTGGTGAGCGTCCATTCCAATGTGATCACTGTTCGAAAAGTTTTGCTCAAAGCAATGATTTGAAGGCTCATGTGCGTCGTCATACTGGCGAGCGATTTAAATGCAGTCACTGCGATGCAAGTTTCTTGCAATTGTATGGTTTGCGACAACATGCATTGGTAGCACATGGTGTTCAAATTGACACTATAACTGGACGTTTGCAAAAGTTTCCCAAACTTGAGGCAACTCCAGAAGACGTAATGCAAAGAACGTTACAAGTTGCTTTAGAAAATGCCAGAGCTCATCAAGCACAAGAACAGGTGCAACAAGAGATGCAACAGCAAATGCAACAGTTACCATAG
Protein Sequence
MKTDTNLDMERICRVCLKGNIDLYLLFDENYALNGISLPQILTECTIYKVQRHDELPHQICSSCMEAAKNAYSFKKRTEQSYRQLVGLLESVSQEQLLTGQKFEQSTQTDKLSIYPCEMCDAKFFEPEDLRNHRLNSHKGTNFKCKVCGQKFARLYRLRGHISLHHPEEGLTHDTKCTVCGKQFSRKDHMRRHLKNVHGKQVPTVERCNKSTLEEPEINLKHELDANQLTEGVLNDSCLTKNEAIWDNYSTRESDSDDDFNATNPISSDSPDDENDEEDEKPLSLLNPVKPVLKVEPADDEICAELTTITEPIILKFEQDGDGFAKICESTHVEDAQAAVENVKLSPKKTTIIREYLGDKPSGRRRTYVKDKDNKCSECQRVFSRHCHLQRHMLTHTMEKPHECTHCLKRFTRRDHLKNHVESQHGDKNYKCDQCDSAFPRKDALERHKASKHSDGPNLNKVHKCEFCEKSFVSKNYLRKHHLMHTDRIFSCKLCDDTFKERAQLREHEKTHNAARNYLCSICGESFARNDYLRVHMRRHTGEKPYKCQYCDKGFPRATDLNVHVRYHTGHKPNLCTLCGKGFHRAYNLTIHMRTHTGERPFQCDHCSKSFAQSNDLKAHVRRHTGERFKCSHCDASFLQLYGLRQHALVAHGVQIDTITGRLQKFPKLEATPEDVMQRTLQVALENARAHQAQEQVQQEMQQQMQQLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01181324;
90% Identity
iTF_01181324;
80% Identity
-