Basic Information

Insect: Tetanocera ferruginea
Gene Symbol: Hr39
Assembly: GCA_958299015.1
Location: OY282641.1:41442447-41448628[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.17 2.7e+03 -1.2 0.6 134 189 26 81 9 105 0.62

2 3 0.67 1.1e+04 -3.2 5.4 50 129 276 360 208 428 0.55

3 3 1.2e-91 1.9e-87 295.8 8.8 1 408 539 896 539 896 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.17	2.7e+03	-1.2	0.6	134	189	26	81	9	105	0.62
2	3	0.67	1.1e+04	-3.2	5.4	50	129	276	360	208	428	0.55
3	3	1.2e-91	1.9e-87	295.8	8.8	1	408	539	896	539	896	0.85

Sequence Information

Coding Sequence: atgtcaacaatTAAGGCTGAAAATGCGCCACATGGTGGTGGCGCAACAgtaacaaccacaacaacaccATCAAATGTCACGCCCTTCAGCGCCAACATATGCAGCAGCAGTGTTGGTAGCCCATTTCAATTGCCGCACAATGTGAGTAGCAACAATGTCAACGCTGCAACCACAACCACGCGTAACAACGTTTCAGTGACGAACATAAAATGTGAAGCCGACGATTTGCGCATGTGTACGAGCACCACAACTACGACTGGTGCCATGAATGGCAATTTAGTGCCGGTAATAGCAAGCGGTAGCAGCTACTTCAATGGTGGCCATGGTGTTATTAATCATGGTGGCATAAGAATACCTGTGCCGAAAGCTGAAGATTCCGATTCGGAAGCAGAACTGACAAACATTGAAAATCTCAAAGTTACGCGAAGAACGTGCGGCAGCGCAGCTGAAACAACTGGCAACTCCGCGTTGCCTGGAGTCACATCCAATCATAACAAGAATGGACCACGCCCCATGTCGTGGGAGGGCGAACTCTCTGAGCCAGAGACAACGGAAACAGATCTAATGGAAACTGAAAACTCCGTGAGCAACGACAAGCATTATGGAGCGGGTATGGCCACAGGCTTAACGGTCATTAAAAGTGAGGCCACTACCACAACGCCACCCACGGCGCCACCCCCCTCGTCGTTTCAGCATGGCATCAAGCCTGAAATTGAACAAATATCAGTTGAACTTATATCGCCCTACGCTAAAGTGAAGCTGGCCGCCCAGCACAGTCAGCCGCAAAGCGATCCCATCAACCTCAAATATGAACCCGGCCTTGATACAAGCGCTACAGCGCCAGCGTTAAATTCACCACTGCTGGCGCGCAACAAGTCCACCGGCAACTTATTGCCCGCCAATCCTTCGCCCGATTCCGCCATTCATTCCGTTTACACGCATAGTTCGCCCAGCCAGTCGCCATTGACGTCGCGTCATGCTCCCTACACGCCATCGCTTAGCCGCAATAACAGCGACGCTTCGCACAGCTCCTGCTACTCATATAGCTCCGAATTCAGTCCCACACACTCGCCCATTCAGGGGCGGCACTCAGCGGCTGCCGCTGCAGCTGCGGCGGCGGCTGCTGCCTATGCCGGTTATAATGGCGCTTCGCTGCATCACTCCGTCTTGTATCGACCGGTTACGCTAGACAACAACAGTAGCCCGGGTGGCCCACTGACAGCGGCAATGAATGGCAGCGAAGCGCCACACAATCTCAGCAGCAACAGTCGATCTCGTCCCTGTCTGCCTGAAGATATGCAGCTAGATGGcaccagcaacagcagcagcgttGGTGGCAACGCTGGTGCCTCCTCCGATGCGCTCTCCTCACCGGGCATCTCACGGCAACAACTAATCAATTCGCCCTGTCCCATATGTGGCGACAAGATATCCGGTTTCCACTATGGCATATTTTCGTGTGAGTCTTGCAAAGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAAAACTATGTGTGTGTGCGTGGTGGTCCCTGTCCCGTTAGCATATCGACGCGCAAAAAGTGTCCTGCCTGTCGCTTCGAAAAATGCCTGCAGAAGGGTATGAAGCTTGAGGCCATACGTGAAGATCGCACACGTGGTGGACGCTCGACATACCAGTGCTCATACACGCTACCCAACTCCATGCTGAGTCCACTCTTGAGTCCCGAACAACAGAACACCGCATCAGCAGCTGCTGGTGGCATTGGTGGCCAACACCAACAGCAACGCGTTGCTATGTTAAATACAAATGGTGCCAACTCTTACATCACCATCAAAACAGAGCAAGGTGAACATGCAGTCTTGAATGGCGGCTCACAGGCGCGTACAGCTAACAGCATTCCGGTGCTGCTACAGGAAATCATGGATGTTGAACATCTCTGGCAATACAATGAAGCCGAGCTGGCGCGCCTTAATCAACCGCTCAGTACTTCTGCTACCGCCTCCACTCCAGCTTCCGCTACCAGCGCTTCACATCACTCCCCTTCCGCCAGTTCCAATCCCATCTCTACTAATCCACTGCTGGCCAGTGCTGGTCTCTCTTCAAATGGCGAGAATGCAAATCCCGATCTAATTGCGCATCTCTGCAATGTTGCCGATCATCGTCTGTACAAGATTGTCAAATGGTGCAAGAGTCTGCCACTCTTTAAGAATATTTCGATCGACGATCAAATTTGCCTGCTCATCAATTCGTGGTGCGAACTGTTGCTCTTCTCTTGTTGTTTTCGTTCAGTCGATACACCAGGAGAGATACAAATGTCGCAAGGCAAAAAGATTTCCTTGGCACAAGCAAAATCAAGCGGTTTGCAGGCCTGCATTGAACGAATGCTTAACCTGACGGATCACTTGAGGCGTCTGCGTGTCGATCGTTATGAATATGTTGCCATGAAAGTAATTGTGCTGTTGCAATCAGATACTTCTGAACTGCAGGAGCCGGTGAAGGTGCGTGAATGCCAAGAAAAGGCATTGCAAAGCCTTCAAGCCTATACGCTGGCACATTATCCGGATGCACCTTCCAAGTTTGGCGAGCTGCTGCTACGCATACCCGATTTGCAGCGCACGTGTCAgCTGGGCAAAGAGATGCTTACAATCAAGTCACGCGATGGTGGCGACTTCAATTTACTCATGGAACTGCTGCGTGGAGAACATTGA
Protein Sequence: MSTIKAENAPHGGGATVTTTTTPSNVTPFSANICSSSVGSPFQLPHNVSSNNVNAATTTTRNNVSVTNIKCEADDLRMCTSTTTTTGAMNGNLVPVIASGSSYFNGGHGVINHGGIRIPVPKAEDSDSEAELTNIENLKVTRRTCGSAAETTGNSALPGVTSNHNKNGPRPMSWEGELSEPETTETDLMETENSVSNDKHYGAGMATGLTVIKSEATTTTPPTAPPPSSFQHGIKPEIEQISVELISPYAKVKLAAQHSQPQSDPINLKYEPGLDTSATAPALNSPLLARNKSTGNLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSAAAAAAAAAAAAYAGYNGASLHHSVLYRPVTLDNNSSPGGPLTAAMNGSEAPHNLSSNSRSRPCLPEDMQLDGTSNSSSVGGNAGASSDALSSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPEQQNTASAAAGGIGGQHQQQRVAMLNTNGANSYITIKTEQGEHAVLNGGSQARTANSIPVLLQEIMDVEHLWQYNEAELARLNQPLSTSATASTPASATSASHHSPSASSNPISTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIQMSQGKKISLAQAKSSGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTSELQEPVKVRECQEKALQSLQAYTLAHYPDAPSKFGELLLRIPDLQRTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01181191; iTF_01181236; iTF_01415104;
90% Identity: iTF_01181236;
80% Identity: iTF_01415104;