Tmol010081.1
Basic Information
- Insect
- Tenebrio molitor
- Gene Symbol
- -
- Assembly
- GCA_963966145.1
- Location
- OZ014541.1:1169925-1172090[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 3.8 3.2e+02 2.7 0.3 1 23 49 71 49 71 0.80 2 18 0.74 63 4.9 2.6 1 23 139 162 139 162 0.89 3 18 0.075 6.4 8.0 5.0 1 23 171 194 171 194 0.98 4 18 0.0063 0.54 11.4 4.6 2 23 237 258 236 258 0.97 5 18 0.00021 0.018 16.1 3.1 1 23 267 290 267 290 0.95 6 18 0.00089 0.076 14.1 1.6 1 23 299 322 299 322 0.95 7 18 6.2 5.3e+02 2.0 2.9 2 23 331 353 330 353 0.92 8 18 0.00061 0.052 14.6 0.9 2 23 363 385 362 385 0.97 9 18 8.9e-05 0.0076 17.2 2.6 1 23 394 417 394 417 0.97 10 18 0.0012 0.1 13.7 2.8 1 23 426 448 426 449 0.95 11 18 0.56 48 5.3 4.9 2 23 464 486 463 486 0.95 12 18 0.0037 0.32 12.1 2.4 2 23 496 518 495 518 0.97 13 18 0.084 7.2 7.9 0.9 2 23 528 550 527 550 0.94 14 18 0.0055 0.47 11.6 3.6 1 23 559 581 559 581 0.96 15 18 0.21 18 6.6 2.0 2 23 597 619 596 619 0.94 16 18 0.056 4.8 8.4 3.6 1 23 628 650 628 650 0.96 17 18 0.31 27 6.1 6.9 1 23 659 682 659 682 0.92 18 18 6.8e-05 0.0058 17.6 6.7 1 23 691 714 691 714 0.96
Sequence Information
- Coding Sequence
- ATGGCAAATTTGGAACATACAGGGATCATCCTGAAATGTGAATGCGGAAGGATTCACGACTGCGACAAATGTCCTTACGTTAGCAGATCACGTTTTTTTCACCAATTTCCATTATTCAGTTGCGAAACAAACTCTCTAGAAAAGTACAACTGCAAAGAGTGCGATTTTGAAACCGATCTTATGATCGTTTTTGATCGACACATCCGAGAACATCGCAGAAAGAGAATCGACGAACAGAAAAATGACCAAGCAGTAAACAGCTACATTTGCCGAGAGTGCTCGTTCGAAACATATTCAGCGTTAATGTGGATCAAACACTCGAATACTTTATGTTTTAAGACGAAAGAAGATTTCGAGAAAGTAACGTTTGGTAAAGAAGCAAAATTGCATCTCTCCACAGAAGACATTCAATGGTTCAGGTGCGACAAATGCAACTATAAGGCAAATCGAAGATACATTTTAAAACGTCACGATCGGATGAAACACACGTCAAATGAAGAAACATCGTGGTTTCGATGTGAACAGTGCgcttacaaaacaaaactgaaatgCTATCTTAAACGTCACATACTAACTCGACACAAATCTGATGAAGATAAGATCCAATGGCTCAGGTGTGACAAGTGCGACTTCACAGCAAAACACAGATGCAGAATGGAGCATCACAAACTGATCAAACACACAACAGACGAAGAAGCTTTGTGGCTACAGTGCAAACAGTGCccttacaaaacaaaactgaaatgCTCTCTCAGACGTCACATGAATCTGCACAAATCCGACGAAGAAGGAACGTGGTTTTACTGCTTCAATTGTGAGTACAGGACTCGGAGGAAAGGAAACTTGAGACGTCACATGTTGCTGAAACACACCACACCCGAAGCTGTGCAGTGGTTTGCTTGTGACAAGTGTCAGTACCAGTCCAAAACCAAAGATGACTTGCAGAAACACGTAAAACTGCGCCATTCAGACGTAGCCATTGAATGGTTGAAGTGTGACAAATGCGATTTCAAAGCAATACAAAGATACAGAATAAAGCATCACAAACTGATCAAACACACATCAGACGAAGAAGTGTTGTGGCTGCAGTGCGAACAGTGCtcttacaaaacaaaactgaaaggTTCTCTCAAACGTCACATAATGACTGTGCACAAATCCGACGAAGAAGCAAACTGGTTTTACTGTTTCAATTGTGAGTACAGGACTCGGAGGAAAGGGAACTTGACACGTCACATGTTGGTAAAACATACCACACCCGAAGCTGTGCAGTGGTTTGCTTGTGACAAGTGTCAGTACCAGTCCAAAACCAAAGACGAATTGAACAAACACGAAAAAGTGCACCATTCAGACGTAGCGGTGAAGATCGAAAAGAAGATAGAATGGTGGAAGTGCGACAAATGCGACTTCAAAGTAAAACAAAGGTACAGAATGAAGCATCACAAACTGATGAAACACACATCAGACGAAGAAGTGTTGTGGCTGCAGTGCGAACAGTGCtcttacaaaacaaaactgaaaggTTCTCTTAAACATCACATAATGACTCTGCACAAATCCGACGAAGAATCAAAGTGGATTTACTGTTTGAATTGTGAGTACAGAACTCAGAGGAAAGGAAACTTTGGACGTCACATGTTGCTGAAACACACCACAACCGAGGCTGCGCAGTGGTTTGCTTGTGACAAGTGTCAGTACcagacaaaaaacaaatacgaCTTGCACAGACACGCAAAACTGCACAATTCAGATATAGCGGTGAAGATCAAAAAGAAGATAGAATGGTGGAAGTGCGACAAATGCGACTTCAAGGCAAGGCAAAGGTGGCGACTGAGGCAACACGAGCGGTTCAAGCACACGCCGAACGAAGAGGGGGTGTGGTTTCAATGTGAGCAGTGCTCATACAAAACAATACGGAAAGACAACCTGAAATGTCACGTGAACCTCCACAAACCCGATGAAGAAGCGGAATGGTTCTACTGCATCAAGTGCGAGCACAGGACGAAGAGTAAGAAGAATCTGAAACATCACATGTTGCTCAAACACACCGCCCCGGAAGCCGTGCGATGGTTCACTTGTGATAAGTGCCAGTGCAAATTTAAGACGAAATCTTACCTGAACAGGCACCAAAAACTCTTGCATTCTTCCAAAGAAGTTCAAGTGTGA
- Protein Sequence
- MANLEHTGIILKCECGRIHDCDKCPYVSRSRFFHQFPLFSCETNSLEKYNCKECDFETDLMIVFDRHIREHRRKRIDEQKNDQAVNSYICRECSFETYSALMWIKHSNTLCFKTKEDFEKVTFGKEAKLHLSTEDIQWFRCDKCNYKANRRYILKRHDRMKHTSNEETSWFRCEQCAYKTKLKCYLKRHILTRHKSDEDKIQWLRCDKCDFTAKHRCRMEHHKLIKHTTDEEALWLQCKQCPYKTKLKCSLRRHMNLHKSDEEGTWFYCFNCEYRTRRKGNLRRHMLLKHTTPEAVQWFACDKCQYQSKTKDDLQKHVKLRHSDVAIEWLKCDKCDFKAIQRYRIKHHKLIKHTSDEEVLWLQCEQCSYKTKLKGSLKRHIMTVHKSDEEANWFYCFNCEYRTRRKGNLTRHMLVKHTTPEAVQWFACDKCQYQSKTKDELNKHEKVHHSDVAVKIEKKIEWWKCDKCDFKVKQRYRMKHHKLMKHTSDEEVLWLQCEQCSYKTKLKGSLKHHIMTLHKSDEESKWIYCLNCEYRTQRKGNFGRHMLLKHTTTEAAQWFACDKCQYQTKNKYDLHRHAKLHNSDIAVKIKKKIEWWKCDKCDFKARQRWRLRQHERFKHTPNEEGVWFQCEQCSYKTIRKDNLKCHVNLHKPDEEAEWFYCIKCEHRTKSKKNLKHHMLLKHTAPEAVRWFTCDKCQCKFKTKSYLNRHQKLLHSSKEVQV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01410300;
- 90% Identity
- -
- 80% Identity
- -