Basic Information

Insect: Tenebrio molitor
Gene Symbol: ZFHX3
Assembly: GCA_963966145.1
Location: OZ014538.1:46227519-46236803[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.5 3e+02 2.8 0.2 1 22 63 84 63 86 0.80

2 15 0.0006 0.051 14.6 0.4 1 23 98 121 98 121 0.96

3 15 1.3 1.1e+02 4.2 2.6 2 21 197 216 197 220 0.87

4 15 0.053 4.5 8.5 1.3 1 23 232 257 232 257 0.91

5 15 0.0044 0.37 11.9 1.6 1 23 275 297 275 297 0.97

6 15 0.00095 0.081 14.0 0.7 2 23 304 326 303 326 0.94

7 15 0.00025 0.021 15.8 3.1 1 23 432 456 432 456 0.92

8 15 0.0075 0.64 11.2 0.6 1 22 476 497 476 500 0.89

9 15 0.0015 0.13 13.4 0.2 1 23 549 573 549 573 0.93

10 15 0.012 1 10.5 0.0 2 21 636 655 635 656 0.94

11 15 0.44 38 5.6 2.5 2 19 759 776 758 781 0.90

12 15 0.00016 0.014 16.5 2.5 1 23 1349 1371 1349 1371 0.99

13 15 0.0007 0.059 14.4 0.3 1 23 1463 1485 1463 1485 0.98

14 15 0.0087 0.74 11.0 0.4 2 23 1631 1653 1630 1653 0.96

15 15 0.8 68 4.8 3.6 3 23 1907 1929 1906 1929 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.5	3e+02	2.8	0.2	1	22	63	84	63	86	0.80
2	15	0.0006	0.051	14.6	0.4	1	23	98	121	98	121	0.96
3	15	1.3	1.1e+02	4.2	2.6	2	21	197	216	197	220	0.87
4	15	0.053	4.5	8.5	1.3	1	23	232	257	232	257	0.91
5	15	0.0044	0.37	11.9	1.6	1	23	275	297	275	297	0.97
6	15	0.00095	0.081	14.0	0.7	2	23	304	326	303	326	0.94
7	15	0.00025	0.021	15.8	3.1	1	23	432	456	432	456	0.92
8	15	0.0075	0.64	11.2	0.6	1	22	476	497	476	500	0.89
9	15	0.0015	0.13	13.4	0.2	1	23	549	573	549	573	0.93
10	15	0.012	1	10.5	0.0	2	21	636	655	635	656	0.94
11	15	0.44	38	5.6	2.5	2	19	759	776	758	781	0.90
12	15	0.00016	0.014	16.5	2.5	1	23	1349	1371	1349	1371	0.99
13	15	0.0007	0.059	14.4	0.3	1	23	1463	1485	1463	1485	0.98
14	15	0.0087	0.74	11.0	0.4	2	23	1631	1653	1630	1653	0.96
15	15	0.8	68	4.8	3.6	3	23	1907	1929	1906	1929	0.90

Sequence Information

Coding Sequence: ATGTCAAAAGTAGGAATCGTTCGGTTTCGGTCGGTCTGTCGGCGGCTGATAATTGTGTGTCTGCCCCCAGAGCGGCGGGACAGCGTCAACTCCGAGCTGAGCCAGCTGGAGTCGAGCCGCGACCCCGTGAAAACGGAACCCCGCGAAGACAACGAAGACGGCGCCAACCCCGAGAGCGGCCCCCAGCACGTGTGCCCCTACTGCGAGTACAGCAGCGAGAGCGAGATGCGCATCCAGGCGCACGTCCTCGCCCAGCACGGCACCAGCAGCGCTTCCACCGACGGGCCGGTGTTCCAGTGCCCCCTCTGCCAGGACTCGTTCAAGGAGCGCTCCAGCCTGGAGCGGCACGTGATGCAGATCCACTCGGTGAACAGCGAGGGTCTGCAGCGGCTGCTGATGCTGGTGGACCAGAGCCACTGGCTGAACCGGGCGTCGCGCACCCCCACGCCCAACAACTCGGCCGCCGCCCCCAGCCAGATCGTGTCGCCCACCTCCGTGTCTTCCAAGGACTCGGCCAAGCAGGAGAAGGGCGAGGATGTCGAGATGATGTCGCCCGCCAGCGAGGACAATAACGAGCTGGAAGCGGAGCGCTGCGGGACCTGCTTCAAGACCTTCAAGAACATCGACGAGCTGTGTTTCCACCAGAACGAAACGGGGCACCTGGAGATCAAACAGACGCCGAGCGGGCCGGGGTACGTGTGCTGGAAGAAGGGGTGCAATCAGTTTTTTCCGACGGCGCACTCCCTCCAGATGCACTTCAAGGACGTCCACGCCAAGAACTCCATCAGCAACATGTCGGTCTCGGAAAAGCACGTCTACAAGTACAGGTGCAATCAGTGCTCGCTGGCGTTCAAGACGCTGGAGAAGCTGCAACTGCACTCGCAGTACCACATGATCAGGGACGCCACCAAGTGCGTACTGTGCGGGAGGAGTTTCCGGTCGCTGGTGGCGCTGCACAAGCACGTGGAGAGCGTCCACTCGGACTTGACAGACGAAGAACTGACGGTGTACAAGCAGAGCTTGATGAGCAATCCCCTGCTTCTGGCGGGGCTGCAAGGACAAGTGCTGGACAGTTCCACCaacgatattttaaagaagGAGTCTCTGGCCGGGGAGGAAGAGGCGACAGAGTGCGACGACAGCAAAGAGATCAACACCAGTCACGACGACAGCAATCAAAACGACGGAGAGAACTCGGACGACAGCATCATCTACAAAGACCAACAGTTCCTAGAAGATTACCTGAACAGTCAAGCGATCGCGGAGGACAGCTACAACGATCCCAACAGGAAGTACAAGTGTCACCGGTGCAAAGTCGCCTTCACCAGACAGAGCTACTTGACGGCTCACAACAAAACTCTTTTGCATCGAAAAGGCGAGAAGCTGAGCTACCCAATGGAAAAGTACCTGGACCCAAATAGGCCTTACAAATGCGACGTGTGCAAAGAGAGCTTCACCCAAAAAAACATCCTCCTAGTCCACTACAACTCGGTCAGTCACCTGCACAAGTTGAAGCGCGCCATGCAAGAACAACAGcagaacaacaacaacaatccGGCGGTGTCGCCGGTGATCGGGAGCCAAGCGCAGAACTTGACGCTGACGCCGAAGAGCACCTCCAGCGAAGAGGACGACAAGAAGCGGTACCGGTGCAACATCTGCAAGGTGGCGTACACGCAGGGCAGCACTTTGGATATTCATATGCGCAGCGTGCTGCACCAGACGCGGGCCAGCAAGCTGCAGGACTTGGCGATGACCGGGCAGATAGACCTGTCGAAGCCGCTGATAGAGCAACCGGAGTCGTTGCAGTCTCCGAAACAGAGCAGCCCCTTGCCGGGCGGTGGGGAGAAGACGTCTCCCACCCCTCCGTCGCCCGGCCTCGGCACAGGTAGCCAGGGGATGACGAGCTGTCCCAAATGCGGCGCCCTTTTCGGTTCGCAAGATCAGTTGAGCGCACACCAGCAGCTGTACTGCATGTTCGCGGCGCCGATGGCCATCTTCCAAGCGGCGCAAGAGCCCGGCCAGGCGAAGAGTCCGCCCCCCGACGACGACGCCGTCGTCCGACTGTCAATGCCCAAGAAGACGGGCTCGCACATGTACAAACACCTGCTGGAGAGCTTCGGCTTCGACCTGGTGATGCAATATAATGAGAGCCACCAGCGGCGCCAGCGCCAGGCCGAGGAGAAGGCGAGGACGCCGCCCCCGCCGCCAGAGCAGCCCGAGGCGAAGGCCGAGGACGACGCAGAAAGCACCTTACCAGAAGTAAGTAGATCCACGTGCCAACATTGCAATAAAGAGTTCTCTAGCGTGTGGGTGTTAAAGTCTCACTGTGAAGAAGTACATAAAGATTTAGTGCCACTAGAATTCTTAGAAAAGTATGCTCAACAGTTCAAGAACGAATACGAAAAGAAATCGGTGGTCGTGACGGCGGCGACGTCCTCCACCGTTAACAGCCATCCACGGGTAGCGACGCCCGGGGCGCCCACCACGACGACGTCGTCGAGTCCGGGCGCCGACGCCACGCCGGAAAAAGAGGACGAGTCCAAAGACGCGTTGCACGCCAAACTTAACCAACTTAACCTGCAGACGCCGCCGGAGGCCGCGTCCACGGCGCCGTCGACGCCGACGTCGTCGACGACGCCCGCGAGCAGCACCGACTCGCTGCCAGCCAACATCCAGGCGATGATTGCGCAGAGCATGGCGCAGAACCCGATGGCCTTGGCGCAACAAATGTCAGAAATGCAGGCCGCGTTCAATGTCATGCAATTGCAACAGCTCAACTTCAATCCCATGATGCAAATGATGGGCATGGGCCTGCCCCTCGGGCTAAACGCTCTGGCAGCGATGAACTTACAGCCGCCTCTGGTGCCGCTCATGATGCCGCCGCCTCCATACGACCCCATCTCGCAATTCGGCCCCCAAGACCAGCAGGCCATGATGGCCAAACAACAAGCCATGATGCAGCAACAAGCGGCCGTTAACGCTGCTGCGAACCAGAAGCGCGCAAGAACTCGCATCACCGACGACCAACTGAAGATCCTGCGAGCCCACTTCGACATAAACAACTCACCGTCGGAGGAGCAGATCCACGAGATGGCATCGCAAAGCGGCCTTCCGCCCAAAGTCATAAAGCATTGGTTCAGGAACACGCTGTTCAAAGAAAGACAACGAAACAAAGACAGTCCTTATAATTTCAACAACCCACCCTCGACGACGCTCAATTTGGAGGAGTACGAGAAGACGGGCGAGGCCAAGGTGATGCCGCTCAACAGCTCGGGCAGCAGCACCGAAGACGTGAAGAAGGGCACGCCGCCCCCGATCCAGCCCGAGATCAAGACCGAGATGAAAGAGGAACCAGTTGACGAACACAAATTCGACGAGAAGATGCAAGAACCCATCGACGAGAAACCCAACCTTTTTAACCTGCCCCCAAACCTGCAACCCCCGCAAAGTCCCGCCACTTCAGTCGCCAGCTCGGACAACATCAACATGTCGCAAGCCTCCGCCCCCACCACCCCCAACAACCTCACCCTCACCTCCATCATCGCCTCGCAACTCGGCGACACCCTCACCACCAGCACTCCAGCTCTCAACATGTCCACGTCGTCCTCCCACCACGGACTCGCCAGCCCCATGCTGCCGCCCCCCAAGCTCAACCAACAGAATTTTCCCAACCCCAACAACCTCCAAGCCATGCTGCCCCTGACCCCAAACCGCTGCCTCAGTCCTAGTCGAGAGTACAGCAACCCCAGCAGTCAAAGCTCCTGCGGCTCCACGGGGAAACGAGCGAACCGCACCCGCTTCACCGACTACCAGATCAAAGTCCTGCAGGAGTTTTTCGAGAACAACGCCTACCCCAAAGACGACGATCTCGAGTATCTCTCCAAACTGTTGAATCTCAGTCCACGAGTGATCGTGGTTTGGTTTCAAAACGCGCGGCAAAAGGCCAGGAAAGTGTACGAGAACCAACCAGCAGTGGAACCAGCGCCTGGGATAGGCGACGAGAGCGGGGCCAACAGGTTTCAGAGGACCCCGGGGCTCAACTACCAGTGCAAGAAATGCCTCCTGGTTTTTCAAAGATACTACGAGTTGATCCGCCACCAGAAGACGCATTGCTTCAAAGAGGAGGATGCCAAGAGGAGCGCTCAGGCGCAGGCGGCAGCCGCGCAGATCGCGGCGGTGTTGAGCTCCGAAGACTCGAACTCTAGTACCACCGTGGAGCAGTCGCAGCAGCAACAGCAACAGCCCCAGAACAGCATCCAGCACAGTCCGCAGCTGCAGAACGCGGCGCAGAGCCCCATCCAGCCGAACCCGCCGACGACGCCCACCCCCACCAGCGGCAACTACCCGCCGTCGCCGTCCGCTGGTGATAATAAAGAAGGGACGTTTCAGTGCGACAAATGCAACCTAGTTTTTCCCAGATTCGATCTGTGGCGGGAGCACCAGCTGGTCCACATCATGAACCCCAATTTGTTTCCAACCTACCCCCCAGACTCGCCCTTCGGGATTTTGCAACAGCACGCGCAGCTCCAACAGCTGAACGCGAATCTGGGGGACATCACCAAGACCAACTCGCAAAACATACAACACCCTTTGGTCAACATGTTGAACAACGTGGGGGGGCAAAAGAGGAAACTGGAGGAGTTCGAGGTGGAGAGCGACACCTCCGATCAACCCAAAGACAAAAGGTTGAGGACCACGATCTTGCCCGAACAGTTGGACTATCTGTACCAGAAGTACCAGATCGAGAGCAACCCTTCTAGGAAGATGTTGGAGAACATCGCGAGAGAAGTGGGGTTGAAGAAACGAGTGGTGCAGGTGTGGTTTCAGAACACGAGGGCTAGGGAGCGCAAAGGGCAGTTCAGAGCCCACGCGCAAGTGATCAACAAGAGGTGTCCCTTTTGTCCGGCTCTTTTCAAAGTGAAATCTGCGCTGGAGTCTCATCTGACGACGAAGCATGCTGCCAGGGGTGAGGTCAATATCGACGCGCTCCCAGACGAAGAAGTCAGTTTGGAATCTTCTCCTAGTTTGAGTTCTGGAGGGGACAACAAGTTCCAGCAGAACCCGAATATGATGCCTCCTTTATTTCCGACGCTGCATCCAGAAATGGAGAACTCGATAAAAAAGTACTACGAAGAGAGCATGAAGAGATATATTAGTGAGTTGCAAGCGCACGCGTCCTCCTCCAACGGCGACAAGAGCGAGATCAAATCAGGCAAGGAAGAAGGCGAGATCCCGCTCGATTTGTCGAAACCCGTCGACCTATCCAGACCCATGAAAGTGTCCATGGACCACGAGCGCACCATCTGCGACCCCGGCCCCTTGACGGACCTGAGCGAGAGGTCGCTGTGCGACGAGCGCAGCGACTCCATGTCGGAAACCACCGAGATCTTCGACGACGAGAGCAACCCGACGTCTCCAGCCAGCAGCACCCAAAGCAACACCCACCGCCTGTCCAACACCGGCAGCTCCAGCGGCACCAAGCGATTTCGCACCCAAATGTCCTCCGTACAAGTGAAAGTGATGAAGTCGCTCTTCGGCGACTACAAGACCCCCACGATGGCCGAGTGCGAGATGCTGGGCCGCGAGATCGGCCTGCCGAAACGCGTGGTGCAAGTGTGGTTCCAGAACGCGCGGGCCAAAGAGAAGAAGAGCAAGATCGCGCTGCAGAAGGTGCTGGGCGCCCCGGAATCCGACACTCCGGTCCTGCCCGAAGACTGCAAGTTCTGCAATTTCAAATACTCGCACAAGTACTCCATCCAAGACCACATCTTCACCAAGAGCCACATCGCCAACGTGCGCATGCACCTAGAGAACGCCAGCAAGGAGGCGGGCGAGAGCGAGTTCACGGTGCCGCCGCTCCCGGGGGCCTCCTCGGTCACCGCCGACTCCACCACCAACCCGCCGCAGAACCTCAACAACAACACGCACCTCCAGCTGCTGCAGATGGCCGGGATGCCGGCCCCGACCAAGGGGGACCAGGAGGAGAACTCGGAGACGCTGTTCCAGCAGCTCTACGCCCTCGGCAACAACGCCAACTACGGGGTCCAGAACCAGTACGTGCACCACTCGATGTTCGGCGCCAACGGTGAGTACTCGCTGTAG
Protein Sequence: MSKVGIVRFRSVCRRLIIVCLPPERRDSVNSELSQLESSRDPVKTEPREDNEDGANPESGPQHVCPYCEYSSESEMRIQAHVLAQHGTSSASTDGPVFQCPLCQDSFKERSSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNRASRTPTPNNSAAAPSQIVSPTSVSSKDSAKQEKGEDVEMMSPASEDNNELEAERCGTCFKTFKNIDELCFHQNETGHLEIKQTPSGPGYVCWKKGCNQFFPTAHSLQMHFKDVHAKNSISNMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSDLTDEELTVYKQSLMSNPLLLAGLQGQVLDSSTNDILKKESLAGEEEATECDDSKEINTSHDDSNQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQNNNNNPAVSPVIGSQAQNLTLTPKSTSSEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMTGQIDLSKPLIEQPESLQSPKQSSPLPGGGEKTSPTPPSPGLGTGSQGMTSCPKCGALFGSQDQLSAHQQLYCMFAAPMAIFQAAQEPGQAKSPPPDDDAVVRLSMPKKTGSHMYKHLLESFGFDLVMQYNESHQRRQRQAEEKARTPPPPPEQPEAKAEDDAESTLPEVSRSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKSVVVTAATSSTVNSHPRVATPGAPTTTTSSSPGADATPEKEDESKDALHAKLNQLNLQTPPEAASTAPSTPTSSTTPASSTDSLPANIQAMIAQSMAQNPMALAQQMSEMQAAFNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPISQFGPQDQQAMMAKQQAMMQQQAAVNAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSTEDVKKGTPPPIQPEIKTEMKEEPVDEHKFDEKMQEPIDEKPNLFNLPPNLQPPQSPATSVASSDNINMSQASAPTTPNNLTLTSIIASQLGDTLTTSTPALNMSTSSSHHGLASPMLPPPKLNQQNFPNPNNLQAMLPLTPNRCLSPSREYSNPSSQSSCGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAVEPAPGIGDESGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQSQQQQQQPQNSIQHSPQLQNAAQSPIQPNPPTTPTPTSGNYPPSPSAGDNKEGTFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNANLGDITKTNSQNIQHPLVNMLNNVGGQKRKLEEFEVESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHAARGEVNIDALPDEEVSLESSPSLSSGGDNKFQQNPNMMPPLFPTLHPEMENSIKKYYEESMKRYISELQAHASSSNGDKSEIKSGKEEGEIPLDLSKPVDLSRPMKVSMDHERTICDPGPLTDLSERSLCDERSDSMSETTEIFDDESNPTSPASSTQSNTHRLSNTGSSSGTKRFRTQMSSVQVKVMKSLFGDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKSKIALQKVLGAPESDTPVLPEDCKFCNFKYSHKYSIQDHIFTKSHIANVRMHLENASKEAGESEFTVPPLPGASSVTADSTTNPPQNLNNNTHLQLLQMAGMPAPTKGDQEENSETLFQQLYALGNNANYGVQNQYVHHSMFGANGEYSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01278459;
90% Identity: iTF_01409773;
80% Identity: iTF_01409773;