Basic Information

Insect: Pycnomerus fuliginosus
Gene Symbol: ZFHX3
Assembly: GCA_963924575.1
Location: OZ004618.1:27721216-27750239[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 7 4.1e+02 2.6 0.2 1 22 31 52 31 54 0.80

2 16 0.0012 0.069 14.5 0.4 1 23 65 88 65 88 0.96

3 16 1.9 1.1e+02 4.4 3.2 2 21 171 190 171 194 0.87

4 16 0.41 24 6.5 1.3 3 23 208 231 206 231 0.86

5 16 0.0087 0.51 11.8 1.6 1 23 249 271 249 271 0.97

6 16 0.0019 0.11 13.9 0.7 2 23 278 300 277 300 0.94

7 16 0.0005 0.029 15.7 3.1 1 23 407 431 407 431 0.92

8 16 0.015 0.87 11.1 0.6 1 22 451 472 451 475 0.89

9 16 0.003 0.17 13.3 0.2 1 23 524 548 524 548 0.93

10 16 0.0027 0.16 13.4 0.1 2 21 612 631 611 632 0.94

11 16 0.88 51 5.5 2.5 2 19 746 763 745 768 0.90

12 16 0.00032 0.019 16.3 2.5 1 23 1340 1362 1340 1362 0.99

13 16 0.0014 0.081 14.3 0.3 1 23 1455 1477 1455 1477 0.98

14 16 0.017 1 10.8 0.4 2 23 1624 1646 1623 1646 0.96

15 16 1.1 62 5.2 3.2 3 23 1901 1923 1899 1923 0.89

16 16 0.86 50 5.5 0.1 1 21 2088 2108 2088 2109 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	7	4.1e+02	2.6	0.2	1	22	31	52	31	54	0.80
2	16	0.0012	0.069	14.5	0.4	1	23	65	88	65	88	0.96
3	16	1.9	1.1e+02	4.4	3.2	2	21	171	190	171	194	0.87
4	16	0.41	24	6.5	1.3	3	23	208	231	206	231	0.86
5	16	0.0087	0.51	11.8	1.6	1	23	249	271	249	271	0.97
6	16	0.0019	0.11	13.9	0.7	2	23	278	300	277	300	0.94
7	16	0.0005	0.029	15.7	3.1	1	23	407	431	407	431	0.92
8	16	0.015	0.87	11.1	0.6	1	22	451	472	451	475	0.89
9	16	0.003	0.17	13.3	0.2	1	23	524	548	524	548	0.93
10	16	0.0027	0.16	13.4	0.1	2	21	612	631	611	632	0.94
11	16	0.88	51	5.5	2.5	2	19	746	763	745	768	0.90
12	16	0.00032	0.019	16.3	2.5	1	23	1340	1362	1340	1362	0.99
13	16	0.0014	0.081	14.3	0.3	1	23	1455	1477	1455	1477	0.98
14	16	0.017	1	10.8	0.4	2	23	1624	1646	1623	1646	0.96
15	16	1.1	62	5.2	3.2	3	23	1901	1923	1899	1923	0.89
16	16	0.86	50	5.5	0.1	1	21	2088	2108	2088	2109	0.94

Sequence Information

Coding Sequence: ATGAGTCAGCTGGACACGGGGAAGGAGAGCGTCAAGACGGAACCCCGAGAAGACAACGAAGACTTAAACACTTCAGAAGGGCCCCTGCAACACGTTTGTCCTTACTGTGAATACAGCAGCGATTCTGAAATGAGAATACAGGCTCACGTTCTGGCGCAGCATGGCAGCAACAGCGCTTCCATGGAGCAAGTGTTCCAATGTCCTCTATGTCAAGATTCTTTCAAAGAACGGTCTAGTCTAGAGAGGCACGTTATGCAAATTCATTCGGTGAATAGTGAGGGCTTGCAGCGACTATTGATGCTCGTAGATCAGAGCCATTGGTTGAATCAAGCGTCGAGAACTCCGACGCCGAACAACTCCAGTCATCAACAAAGCCAGATAGTGTCGCCTACCTCTGTGTCTTCCAAAGATTCGAATAAGTTAGAAAAGAGCGACGCCAGCAACACAGAGGCTGATAGAGATTTGATGTCGCCATCAGCGAGTGAGGATAACTCTGAACTAGAAGCGGAAAGATGTAGCACGTGTTTTAAAACGTTCAAAAATATAGACGAGTTGTGTTTTCATCAAAACGAAACGGGGCATTTAGAAGTCAAGCAAACACCTAGCGGGCCGGGTTACCTGTGCTGGAAGAAGGGCTGCAATCAATTTTTTCCGACGGCCCACTCGTTGCAGATGCATTTCAAAGATATCCATGCAAGAAATTCCATCAGCAACATGTCAGTGTCGGAAAAGCACGTTTATAAGTATAGATGCAACCAGTGTTCGTTAGCCTTTAAAACTTTAGAAAAATTGCAATTACATTCTCAATATCATATGATTAGAGACGCAACGAAATGTGTTTTGTGCGGTCGAAGTTTTCGATCTTTAGTGGCTCTTCATAAACACGTCGAAAGCGTTCATTCCGAGTTGACCGATGAGGAATTGAGCGCTTACAAGCAAAGTCTGATGAATAATCCGTTGTTGTTGGCGGGTCTACAGGGGCAAGTCCTGGACAGCTCGACCAACGATATATTAAAGAAGGAATCGCTGACGAACGACGACATGGAAACTGCGGATTGCGACGACAGCAAAGAATTAAACACCAGTCATGATGATAGCAATCAAAATGACGGAGAAAATTCAGACGACAGTATTATATACAAAGATCAACAGTTCCTAGAAGATTACCTGAACAGTCAAGCAATAGCCGAAGATAGTTACAACGATCCAAACAGAAAATACAAATGTCACCGCTGCAAGGTAGCTTTTACAAGACAAAGCTATTTGACCGCTCATAACAAAACCCTTTTGCACCGGAAGGGCGAGAAACTAAGCTATCCTATGGAGAAGTACCTGGACCCAAATCGGCCTTATAAATGTGACGTTTGTAAAGAAAGTTTCacgcaaaaaaatattttactagTCCATTATAATTCTGTTAGTCACCTACATAAATTAAAGCGGGCAATGCAAGAgcaacaaaataataataacaacCCGGCTGTGAGTCCGGTAATGGGAAATCAATCAACACACAATTTAAGTTTAACGCCGAAAAGTACTTCATCCGAAGAAGACGATAAGAAAAGGTACCGCTGTAATATTTGTAAAGTGGCTTATACGCAAGGAAGTACGCTGGACATTCACATGAGGAGTGTTTTGCATCAGACGAGGGCAAGTAAGCTGCAAGATTTAGCGATGACCGGTCAGATAGACTTATCGAAACCGTTGATCGAGCAACCCGATGCCTTGCAGTCTCCGAAACAAAGTAGCCCTGTCCCAGGTGGTGGGGAAAAGACGTCCCCCACCCCACCATCACCTGGTCTCAATACAGCAGGTAGTCAAGGGATGATGAGCTGTCCCAAATGCGGTGCCCTTTTTAGTTCGCAAGATCAGTTGAGTGCACACCAGCAACTCTATTGCATGTTCGCCACACCGATGGCGATATTTCAATCTGGGCAAGAGCCCTGCCAGGCTAAAAGTCCTCCACCTGGCGAGCAAGATGACTCGATATTGAAATTGAACATACCTAAAAGAACGGGCTCGCACATGTACAAACATTTACTGGAGAGTTTTGGATTCGATCTCGTTATGCAATATAATGAAAGCCACCAGCGGCGCCAGCGACAACGTGAAGCAGAAGAGAAGGCGCGAACACAGTCGAATTCGCCGCCGCCGCAGCCGACGGAATCAGAGCAGCCCGAGCCCAAAGCTGAGGACGACGTAGAAAGCACCTTACCAGAAGTAAGTAGATCAACGTGCCAACATTGCAATAAAGAGTTCTCTAGTGTGTGGGTGTTAAAATCTCACTGTGAAGAAGTACATAAAGATTTAGTGCCACTAGAATTCTTAGAAAAGTATGCTCAACAGTTCAAAAACGAATACGAAAAGAAAACCGTGGTCGTGACGGCGGCGACATCTTCCACGCTAAACAGCAATCCACGTGTCACGACACCGGGTGCGCCAACCACCACCACCTCTACGAGTCCCGGTGCTGACGGTACTCCCGAAAAAGAAGATGACTCGAAAGATGCCTTGCATTCCAAATTAAACCTACAGACACCCCCTGAAGCCGCATCAACGGCTCCCTCGACTCCAACGTCGTCGACAACACCCGCCAGCAGCACAGATTCTTTACCGGCCAATATTCAAGCCATGATCGCACAGAGCATGGCCCAAAATCCGATGGCTCTCGCACAACAAATGACTGAAATGCAAGCAGCCTTTAACGTTATGCAATTACAACAACTCAATTTTAATCCAATGATGCAAATGATGGGGATGGGCCTACCTTTGGGCCTCAACGCTCTTGCCGCGATGAATCTTCAGCCGCCTCTTGTTCCACTTATGATGCCACCCCCACCTTATGATTCAATGTCGCAATACGGGCCTCAAGATCAGCAAGCAATGATGGCCAAACAACAGGCCCTAATGCAGCAACAAGCGGCTGTTAACGCTGCTGCAAATCAGAAGCGAGCAAGAACGCGGATTACCGACGACCAATTGAAAATTTTGCGTGCACATTTCGATATAAACAACTCACCATCTGAAGAACAGATCCACGAGATGGCATCGCAAAGCGGTCTTCCACCTAAAGTCATAAAGCATTGGTTCAGAAATACTCTGTTTAAAGAAAGACAACGAAACAAAGACAGTCCTTACAATTTCAACAACCCGCCTTCGACTACGCTTAACTTGGAAGAATATGAAAAGACTGGTGAAGCTAAAGTTATGCCCTTAAATAGTTCCGGAAGTAGTACTGAAGATAACGCAAAACATCCTAAAAGTTCACCACCTCCACCTCCCACGGAAATTAAAACAGAATTGAAAGAAGAACCAATAGATGAAACTTGCATCAAAATTTCAATGGAACCGGATAAAATTCAAGAGCCAATCGACGAAAAGCCTAATATCTTCAATTTGCTCCCCAGTCTTCAGCCACCCCAAAGTCCAGCTACCTCAGTTGCAAGTTCAGAAAACCTAAATTTATCTCAATCATCGGCACCAACGACACCTAACAGTTTGACCTTAACTTCGATTATTGCGTCACAACTTGGAGATACGTTGACCACCAACACCTCCGCACTTAACATGTCTACCTCCACACATCACGGTCTACCCAGTTCCATGCTGCCGcctccaaaattaaatcaacagaATTTTCCAAATCCCAATAATCTTCAAGCAATGCTGCCCTTAACTCCTAACCGTTGCCTCAGTCCAAGTCGAGAATACAGTAATCCTGGAAGTCAGGGTTCCTGTGGTTCAACTGGCAAACGAGCAAACCGAACACGATTCACGGATTATCAGATTAAGGTCTTGCAggagttttttgaaaacaatGCGTATCCGAAAGATGATGATTTGGAATATCTATCAAAGCTCCTCAACTTAAGCCCCAGGGTTATAGTGGTTTGGTTTCAAAATGCCAGACAAAAAGCTCGGAAAGTCTATGAAAATCAGCCTGCAGCTGAACCAGCGCCGGGTATTGCAGATGAGGCGGGTACAAATAGATTTCAAAGAACCCCTGGTTTAAATTATcaatgcaaaaaatgtcttcTTGTGTTCCAAAGATATTACGAATTAATCAGACATCAAAAAACGCATTGCTTTAAAGAAGAGGATGCAAAAAGATCAGCGCAAGCACAGGCAGCAGCGGCCCAAATCGCTGCAGTTTTAAGTTCTGAAGATTCAAATTCAAGTACAACGGTAGAACAATCTCAACAGCAACAGCAACAGCAACCAATGAATGTTCAAAATAGTCCCCAATTGCAAAACTCTGTCCAGAGCCCCCCAATTCAGTCTAATCAGTCGACAACTCCGACTCCAACAGGGGGCAATTTCCCACCTTCTCCTTCAGGCCAAGACTCAAAAGAAGGAACGTTTCAATGTGATAAATGCAATTTGGTATTTCCAAGGTTTGATCTTTGGCGAGAACATCAGCTAGTTCATATAATGAATCCAAATTTATTTCCAACATATCCTCCAGATTCTCCCTTCGGGATTTTACAGCAACATGCACAACTCCAACAACTAAATGCCAATCTGGGGGATATTTCGAAAACAAATCCCGCTCAAAATATTCAACATCCTCTAATGAATATGTTAAATAATGTTGCTGGACAGAAAAGAAAAATGGATGAATTTGACGCTGAAAGTGATGCTTCAGATCAACCGAAAGATAAGCGATTGCGAACAACAATTTTACCGGAGCAATTGGATTATCTCtaccaaaaatatcaaattgaAAGCAATCCTTCGAGAAAAATGTTAGAGAACATTGCTAGAGAAGTTGGTTTGAAGAAGAGGGTCGTCCAAGTTTGGTTTCAAAACACTAGGGCTCGCGAAAGAAAAGGCCAGTTTCGAGCTCACGCCCAAGTAATTAATAAACGCTGTCCATTTTGCCCAGCTTTGTTTAAAGTTAAATCTGCCCTAGAATCTCATTTAACGACGAAGCATGCTGCAAGAGGTGAAGTCAACATCGATGCTCTCCCAGATGAAGAAGTAAGTCTTGAATCTTCACCAAGCCTCAGCTCCGGAGGTGACAACAAATTCCAACAAAATCCAAACATGATGCCTCCGTTATTTCCCACGTTGCATCCAGAGATGGAGAATTCGATCAAGAAGTATTATGAAGAAAGCATGAAGAGGTATATTAATGAACTACAAGCCCATGCCTCGTCATCGAATGGTGACAAAAGCGAaattaaaacaatcaaagaAGAAGGCGAGATTCCTCTAGATCTGTCAAAACCAGTGGACTTATCCCGACCGATGAAAGTATCCATGGATCATGAGCGGAATATTTGTGATCCGGGGCCGTTGACTGATTTAAGCGAAAGATCACTTTGTGATGAAAGAAGCGACTCAATGTCCGaaacaacagaaatttttgacGATGAAAGTAATCCAACGTCTCCTGCTAGCAGTACGCAAAGTAACACACAAAGAATGTCTAATAACAGTGGATCTGGAGGAACAAAACGATTTCGAACTCAAATGTCATCAGTTCAAGTAAAAGTTATGAAATCTTTGTTCTCTGATTATAAAACTCCAACAATGGCAGAATGTGAAATGTTAGGTCGAGAAATTGGACTTCCGAAAAGAGTTATACAAGTTTGGTTTCAAAATGCAAGAGCCAAGGAAAAGAAAAGCAAGATCGCTCTACAAAAGGTGTTAGGTACACCAGAAACAGAGAACAATCCAGTTCTACCGGACGATtgcaaattttgtaattttaaataTTCTCATAAATATTCCATCCAAGATCATATTTTTACAAAGAGCCATATCAGTAATGTCAGACTACATCTAGAGAACACGCATAAAGACTTAGAAGCGAATGAGTTCACCGTTCCTCCTCTTCCTGGTGGTTCAGGCTCTGTTACTGCCGATTCCACGACAAATCCTCCgcaaaatttaaataacaaCACACATATGCAACTTCTGCAAATGGCGGGCATGCAAATCCCTAACTCCATCAAAGCCGactctgaagagaattccgaAACGTTGTTTCAACAGCTCTACAACCTGGGAAGTAATGCCAGTTACGGGGTCCAAAATCAGTATATGCACCACTCCATGTTTGGCACGAATGGGGGAGCCGGAGGACTGCTTCTAGATACGGGCTCCGGTCCATCATTCCTCCCGCTGCCTGCTCCGGTGTTGGAGCAAGTAGCGGCGGGCAACTCGGAACCCGGAGTGACGACTCTGAAACTGCCGGATCCTCACCAGAAGCCGACAGATATTAATATCCGCGAAACCGATATCGAAGTTTGTTTCGTATGTAAAAAGTGCCGTTTAGCATTCGCTGGTGAATCACCTCTTTTAGGCCACCAGAGGCAGTGTTACGGTGGTAATCAAGAAAATCGCGGAGCTTTCCGAATAGTTCAGAGCGGTTATGAGTGTAGGGCTTGCAATACCGAACGCTTTAAAAACGTCATCGAGTTAAGGCGCCATTGCGAGTGTGAATCTCACGTGAAAAGTAGTAAAGTAATGAATTCGTCACTGCCGCCCCCATCAGAATCTCCTCTTAGTCACGAAATGGAAGACGTGGTCAATCAAATCACACTGCTGGCAGCCCGGGCTGCTCAAGAAGCGGTGCCTGAGGGCGGCAGAGTGGTCGATTCCAATTCCAACACCTTCTGCCAAGAGAGAAAAGGTCGGTTTTTGACACCCGCCGACGTACCTCAGACTTTGACTAGCGCCGGCCACTGA
Protein Sequence: MSQLDTGKESVKTEPREDNEDLNTSEGPLQHVCPYCEYSSDSEMRIQAHVLAQHGSNSASMEQVFQCPLCQDSFKERSSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTPTPNNSSHQQSQIVSPTSVSSKDSNKLEKSDASNTEADRDLMSPSASEDNSELEAERCSTCFKTFKNIDELCFHQNETGHLEVKQTPSGPGYLCWKKGCNQFFPTAHSLQMHFKDIHARNSISNMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELSAYKQSLMNNPLLLAGLQGQVLDSSTNDILKKESLTNDDMETADCDDSKELNTSHDDSNQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNPAVSPVMGNQSTHNLSLTPKSTSSEEDDKKRYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMTGQIDLSKPLIEQPDALQSPKQSSPVPGGGEKTSPTPPSPGLNTAGSQGMMSCPKCGALFSSQDQLSAHQQLYCMFATPMAIFQSGQEPCQAKSPPPGEQDDSILKLNIPKRTGSHMYKHLLESFGFDLVMQYNESHQRRQRQREAEEKARTQSNSPPPQPTESEQPEPKAEDDVESTLPEVSRSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKTVVVTAATSSTLNSNPRVTTPGAPTTTTSTSPGADGTPEKEDDSKDALHSKLNLQTPPEAASTAPSTPTSSTTPASSTDSLPANIQAMIAQSMAQNPMALAQQMTEMQAAFNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDSMSQYGPQDQQAMMAKQQALMQQQAAVNAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMASQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSTEDNAKHPKSSPPPPPTEIKTELKEEPIDETCIKISMEPDKIQEPIDEKPNIFNLLPSLQPPQSPATSVASSENLNLSQSSAPTTPNSLTLTSIIASQLGDTLTTNTSALNMSTSTHHGLPSSMLPPPKLNQQNFPNPNNLQAMLPLTPNRCLSPSREYSNPGSQGSCGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAAEPAPGIADEAGTNRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQSQQQQQQQPMNVQNSPQLQNSVQSPPIQSNQSTTPTPTGGNFPPSPSGQDSKEGTFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNANLGDISKTNPAQNIQHPLMNMLNNVAGQKRKMDEFDAESDASDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHAARGEVNIDALPDEEVSLESSPSLSSGGDNKFQQNPNMMPPLFPTLHPEMENSIKKYYEESMKRYINELQAHASSSNGDKSEIKTIKEEGEIPLDLSKPVDLSRPMKVSMDHERNICDPGPLTDLSERSLCDERSDSMSETTEIFDDESNPTSPASSTQSNTQRMSNNSGSGGTKRFRTQMSSVQVKVMKSLFSDYKTPTMAECEMLGREIGLPKRVIQVWFQNARAKEKKSKIALQKVLGTPETENNPVLPDDCKFCNFKYSHKYSIQDHIFTKSHISNVRLHLENTHKDLEANEFTVPPLPGGSGSVTADSTTNPPQNLNNNTHMQLLQMAGMQIPNSIKADSEENSETLFQQLYNLGSNASYGVQNQYMHHSMFGTNGGAGGLLLDTGSGPSFLPLPAPVLEQVAAGNSEPGVTTLKLPDPHQKPTDINIRETDIEVCFVCKKCRLAFAGESPLLGHQRQCYGGNQENRGAFRIVQSGYECRACNTERFKNVIELRRHCECESHVKSSKVMNSSLPPPSESPLSHEMEDVVNQITLLAARAAQEAVPEGGRVVDSNSNTFCQERKGRFLTPADVPQTLTSAGH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01277504; iTF_01410253; iTF_01409773;
90% Identity: iTF_01277504;
80% Identity: iTF_01277504;