Tmol009085.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tenebrio molitor
Gene Symbol
KEAP1
Assembly
GCA_963966145.1
Location
OZ014540.1:25182163-25184944[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 3.4e-33 1.2e-30 106.5 0.0 3 109 60 164 58 165 0.95

Sequence Information

Coding Sequence
ATGATTTCGATGGACGACGACTGTTGGCCCGCCGATTTAGACTATAGAATGGACGGGGACGAGGACAGCTACTGCAGCAAGTCGCACTCGCGCCAAAATGGCGTCCACGTGTCCGACCTGGGCGACATGAGCTTCATGATGTTGGACTACATCAAGGAAGCGATGAAGGCCATGGACATGATGCGGGGTCATCAAATGCTGACCGATATCACTCTGGAAGTCGGCCACGAAGTGTTCTACGCCCACCGAGTGGTCCTCGCCGCCGCCAGTCCCTATTTCAAAGCGATGTTCACCGGCGGTTTGAAGGAGTGCGAGATGACGCGGATCCCTCTGCAAGGAGTCTCCGCCACCGCCATGGCCAGACTGATCCACTTCATGTACACAGGAAGGATCAGAGTGACGGAGAACACCGTGTGCCAATTGTTACCCGCCGCGACAATGCTACAAGTGACGAACGTAATACAAGCCTGCTGTGATTTTTTAGAAAGACAATTAGACCCTAGCAACGCGATCGGCATCGCCAGCTTCGCCGAGCAGCACGGCTGCATCGAGCTGTGCAAGAAGGCCAACCAGTACATTGAACGCCACTTCTGTCAGATCTGCCAAGAAGAAGAGTTTCTTCAACTGAACGCACTCCAGTTGATCACGTTGATCAAGAAAGACGAACTGAACGTCCAAGACGAGAAGGAGGTCTACAACGCGGTGCTCAAGTGGGTCAGGCACGACGAGGAGAACAGACACAAGAAGATGGAGCACATATTGAGCGCGGTCAGGTGCCAGTTTCTGCCACCCAAGTTCCTCAACGATCAGATGACCAACTGCGAGGTCATCAAGAAGGCGCCGGCCTGCAGGGAATACTTAGCTAGAATATTTAAGGATCTGACATTACACATACGTACCGTTGTCAAAGAAAGGACGCCGAATATACCGAGAGTGATATACATCGCGGGTGGGTACTACAGACAATCTCTCGACGTCTTAGAAGGTTACAATATCGACGACAAGACGTGGCACAAGCTGGACAGTCTGACAGTACCAAGATCTGGACTAGGAGGAGCTTTTCTAAAAGGGACTTTCTATGCAGTGGGGGGACGAAACAACGCCCCCGGTAACAGTTACGATTCGGACTGGGTCGACAAGTACAACCCTGTCAAAGACCAATGGCGACCTTGTAGTCCCATGTCCGTACCAAGAAACCGAGTGGGGGTGGCAGTAATGGACGGTTTACTGTACGCAGTCGGGGGTAGCGAAGGTTCCAAGTACCACAACAGCGTAGAATGTTACGACCCCGATCTGGACCGATGGACGACCATCAAAGCGATGCACTTCAAGCGGCTGGCCGTGGGGGTGGCAGTAGTCAACCGCCTCCTCTACGCGATCGGCGGCTACGACGGCGTGCAGAGACACAACAGCGCCGAGTGCTACCACCCCGAGAACAACGCCTGGGCGATGATAGCCCCGATGCACACCCAACGGAGCGGCGCGGGGGTGGCGGCGATCAACCAGTACATCTACGTGGTGGGAGGGTACGACGGCTCCAAACAGTTGAACACGGTGGAGAGGTACGACACGGAGAAAGACGTGTGGGAGTACGTGGCGAGCATGAAGATCGCGAGGAGTGCGCTCAGCGTGACGGTTCTCGACTGCAAGATCTACGCGATGGGTGGCTACAACGGACAGGATTTCTTAGCCAACGTGGAGATCTACGACCCGTTGAGGGACGTATGGGAGGACGGGGAACCGCTCACTTCGGGGCGGTCAGGTCACACGAGTGCGGTTTGTTATCAGCCGCCGTGTACGCAGAAGTGCAGGATTTTGTCGCAGTTCAGTAACAGTTCGTGCTCGACGTCATCTTCCGCGATCAAGTAA
Protein Sequence
MISMDDDCWPADLDYRMDGDEDSYCSKSHSRQNGVHVSDLGDMSFMMLDYIKEAMKAMDMMRGHQMLTDITLEVGHEVFYAHRVVLAAASPYFKAMFTGGLKECEMTRIPLQGVSATAMARLIHFMYTGRIRVTENTVCQLLPAATMLQVTNVIQACCDFLERQLDPSNAIGIASFAEQHGCIELCKKANQYIERHFCQICQEEEFLQLNALQLITLIKKDELNVQDEKEVYNAVLKWVRHDEENRHKKMEHILSAVRCQFLPPKFLNDQMTNCEVIKKAPACREYLARIFKDLTLHIRTVVKERTPNIPRVIYIAGGYYRQSLDVLEGYNIDDKTWHKLDSLTVPRSGLGGAFLKGTFYAVGGRNNAPGNSYDSDWVDKYNPVKDQWRPCSPMSVPRNRVGVAVMDGLLYAVGGSEGSKYHNSVECYDPDLDRWTTIKAMHFKRLAVGVAVVNRLLYAIGGYDGVQRHNSAECYHPENNAWAMIAPMHTQRSGAGVAAINQYIYVVGGYDGSKQLNTVERYDTEKDVWEYVASMKIARSALSVTVLDCKIYAMGGYNGQDFLANVEIYDPLRDVWEDGEPLTSGRSGHTSAVCYQPPCTQKCRILSQFSNSSCSTSSSAIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00904182;
90% Identity
iTF_01480232; iTF_00415209; iTF_00852937; iTF_00870668; iTF_01481009; iTF_00753074; iTF_01568114; iTF_00639641; iTF_01311643; iTF_00078698; iTF_01329905; iTF_01283509; iTF_00813812; iTF_01022320; iTF_00841941; iTF_01366426; iTF_00814496; iTF_00987232; iTF_01278266;
80% Identity
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