Trug005541.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Temnothorax rugatulus
Gene Symbol
KLHL5
Assembly
GCA_035220575.1
Location
JASTWL010000045.1:809271-813365[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.7e-27 9.1e-25 88.4 0.1 3 109 20 124 18 125 0.95

Sequence Information

Coding Sequence
ATGTCATGCGTGTCCATCTCGCCGAAGCACGCGGAAAGTAGCCTCCGAATTATGGAGAGTTATCTGCACAAGCAACAGCTGACAGACGTCACACTGATCGCGGGAAATAAGCGTGTCCCAGCTCATCGATTAGTACTCAGTGCTGGCTTAGAATATTTTGCTGCCATGTTCACAAGCCCTCTGCGAGAATCGGCACAAAATGAAATAGAATTAATGGATGTTGATGGAGATGCTTTATGGGCTTTGGTTCTTTATTGTTATACAGGTTGCATAGAATTGCAGGAAGATACCGTAGAGACTCTACTTGCAACAGCATGTTTGTTACAATTGAATCCAGTTATTAAAGCGTGCTGTCAGTTTCTCGTCAAACAACTTCACCCAAGCAACTGTCTGGGCATACGGATGTTCGCCGATACGCAGGGTTGTTCGGAATTGGTTGAATACGCACACGCGTACACCACCAAACATTTCATGGAAGTTACAAAAAATCAAGAATTCTTACTGCTATCTGCCAATGAAGTTGCCAAGTTACTGGAATCTGAGGATCTTAATGTTCCCTCGGAAGAAACTATCTTTCATgcTTTACTGACTTGGCTGGGACACGATCCAGAAAACAGGAGCAAAGATGCCAGTAAATTATTAGGTTTAGTTAAATTACCATTGCTATCACCCGCGTTTATAGCTGACAATATTGAGAGTAACGAAATGTTCAAAGACCAAAGAATGGTGCAGGAATTAGTAATGGAAGCATTTAAGTATCATTTGCTGCCTGAGCGAAGATCTTTGCTTCAAACAGGCAGAACGAAACCCAGAAAAGCCACTGTGGGTACGTTGTTAGCTGTCGGAGGGATGGACGAAAATAAAGGTGCACCATCTGTAGAGGCATTTTCATTACGCGATAATGCCTGGAGATCTCTAGAATTTTGCGATAAACCCGGGTCAATCATAAACTGTGCAAGATTTGGCGCAGTAGTAGTCGGTGAAAATTTGATTGTCGCGAGCGGTAAAGATTACAGTTATTATGATACATTGGACACAGTAAAATGCTTCAATTTCTCCACTCTTACGTGGAGCACTCTACCACCTATGAATGTTCGTCGACAAGAATTAGGAGTGGCAGTCTTAGGTGGACTTTTATATGCTGTTGGTGGTTATGACGGTTGGAGTTTTCTTGATGCGGTAGAGAGATGGGATCCGGCAACGCGTCAGTGGAGTTCAATATGTCCTATGTCCATACAAAGATCTACAGTCGGTGTAGCTGTGTTAAATGATAAATTGTACGCTGTAGGAGGAAGAAATAGCAGTTCCTGCTTAAATACAGTAGAATGTTACGATGCGCTCAGGAACAAATGGACACCGTGCGCACCTATGTCGAAGAGACGAGACGGCGTAGGCGTAGGAGTAGTGAATGGTTGTCTTTATGCACTCGGTGGTCACGACGCTCCAGCTAGCAATCCCAATCCTAGCAGATTCAACTGTGTAGAAAGATATGATCCTAAAACCGATACATGGACTATGGTTGCGCCAATGAGTGTGCCCCGGAATGCAGTTGGTGTGTGCGAATTAGGTGACCGACTTATGGCCGTGGGAGGACACGACGGCCAACAATATCTCACACTAGTGGAAGCCTACGATCCACATCTCAACGAATGGGAACCTGTTGCTCCTCTTAAGGCTGGCCGTGCGGGACCCTGCGttgttgtaaaaaatttaaCCAATAACAtgtataatagattattcttaCTAAACGATCAGTAA
Protein Sequence
MSCVSISPKHAESSLRIMESYLHKQQLTDVTLIAGNKRVPAHRLVLSAGLEYFAAMFTSPLRESAQNEIELMDVDGDALWALVLYCYTGCIELQEDTVETLLATACLLQLNPVIKACCQFLVKQLHPSNCLGIRMFADTQGCSELVEYAHAYTTKHFMEVTKNQEFLLLSANEVAKLLESEDLNVPSEETIFHALLTWLGHDPENRSKDASKLLGLVKLPLLSPAFIADNIESNEMFKDQRMVQELVMEAFKYHLLPERRSLLQTGRTKPRKATVGTLLAVGGMDENKGAPSVEAFSLRDNAWRSLEFCDKPGSIINCARFGAVVVGENLIVASGKDYSYYDTLDTVKCFNFSTLTWSTLPPMNVRRQELGVAVLGGLLYAVGGYDGWSFLDAVERWDPATRQWSSICPMSIQRSTVGVAVLNDKLYAVGGRNSSSCLNTVECYDALRNKWTPCAPMSKRRDGVGVGVVNGCLYALGGHDAPASNPNPSRFNCVERYDPKTDTWTMVAPMSVPRNAVGVCELGDRLMAVGGHDGQQYLTLVEAYDPHLNEWEPVAPLKAGRAGPCVVVKNLTNNMYNRLFLLNDQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01245317; iTF_01269889; iTF_00109923; iTF_00868963; iTF_00264392; iTF_01087306; iTF_01266955; iTF_01267659; iTF_00730157; iTF_01270605; iTF_00452656; iTF_00867538; iTF_00729427; iTF_00730867; iTF_00769779; iTF_01271315; iTF_00265108; iTF_01268373; iTF_00280663; iTF_00417688; iTF_01254905; iTF_01269148; iTF_00898878; iTF_01077568; iTF_01099328; iTF_01498309; iTF_00963272; iTF_00761057; iTF_00860481; iTF_00862657; iTF_01130913; iTF_00140674; iTF_00295362; iTF_00734018; iTF_01122530; iTF_01419074; iTF_00360291; iTF_00861251; iTF_01255779; iTF_00231396; iTF_00865412; iTF_01169252; iTF_01454276; iTF_00084645; iTF_00214469; iTF_00232677; iTF_01123141; iTF_01419717; iTF_00296902; iTF_00219879; iTF_00676103; iTF_01475559; iTF_00225320; iTF_00762632; iTF_01066344; iTF_01198760; iTF_00118091; iTF_00218507; iTF_00773899; iTF_00964555; iTF_01071083; iTF_01395211; iTF_00184012; iTF_00223276; iTF_00255180; iTF_00754860; iTF_00756748; iTF_00866092; iTF_00142541; iTF_00225997; iTF_00253677; iTF_00763309; iTF_01424461; iTF_00222606; iTF_00303182; iTF_00393678; iTF_00966094; iTF_01067694; iTF_00087279; iTF_01070447; iTF_01421007; iTF_00089680; iTF_00141296; iTF_00963920; iTF_01067024; iTF_01474800; iTF_00228049; iTF_00460913; iTF_00873874; iTF_00228755; iTF_00961907; iTF_01474035; iTF_00085492; iTF_00864724; iTF_00141909; iTF_00226677; iTF_00252917; iTF_00088918; iTF_00306358; iTF_01065654; iTF_00024695; iTF_00229431; iTF_00360983; iTF_00861975; iTF_00864055; iTF_01418423; iTF_00223960; iTF_01538072; iTF_00064569; iTF_00224633; iTF_01069753; iTF_01420345; iTF_00200890; iTF_00227354; iTF_00770458; iTF_01417786; iTF_00298427; iTF_00866779; iTF_00962587; iTF_00676860; iTF_01068380; iTF_00088125; iTF_00183357; iTF_00221982; iTF_00232062; iTF_00221343; iTF_00982367; iTF_01069055; iTF_00215104; iTF_00230112; iTF_00233312; iTF_00297664; iTF_00983040; iTF_01473280; iTF_00182699; iTF_00015460; iTF_00182053; iTF_01477006; iTF_00181392; iTF_01261907; iTF_00016762; iTF_00014814; iTF_00016115; iTF_01405879; iTF_00126081; iTF_00129859; iTF_01407492; iTF_01015941; iTF_00885255; iTF_01228456; iTF_01423017; iTF_00129099; iTF_00126829; iTF_00128334; iTF_01422318; iTF_01423758; iTF_01421648; iTF_01354707; iTF_01476340; iTF_00863350; iTF_01409303; iTF_01520376; iTF_01229116; iTF_01408381; iTF_00765758; iTF_00127583; iTF_00765759; iTF_01355520; iTF_01407494; iTF_01407498; iTF_00215787; iTF_01407499; iTF_01513553; iTF_01233733; iTF_01512901; iTF_01514895; iTF_01232464; iTF_01233075; iTF_01234419; iTF_01514231; iTF_01235098; iTF_01409300; iTF_01409301; iTF_01409305; iTF_00219197; iTF_01405883;
90% Identity
-
80% Identity
-