Basic Information

Gene Symbol
-
Assembly
GCA_030848795.1
Location
JASTWM010000075.1:506791-509559[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 3.8e-05 0.0059 18.3 1.8 1 23 44 66 44 66 0.97
2 17 0.00011 0.016 16.9 1.2 1 23 68 90 68 91 0.96
3 17 0.0014 0.22 13.3 0.7 2 23 126 148 125 148 0.95
4 17 0.0015 0.23 13.2 0.9 3 23 155 176 154 176 0.95
5 17 0.0006 0.094 14.5 0.2 1 23 181 203 181 203 0.99
6 17 0.00062 0.096 14.5 0.9 1 23 212 234 212 234 0.97
7 17 4.7e-05 0.0073 18.0 0.1 1 23 240 262 240 262 0.99
8 17 1.1e-05 0.0017 20.0 0.1 1 23 267 289 267 289 0.98
9 17 0.0051 0.8 11.6 2.6 2 23 375 396 374 396 0.97
10 17 0.00036 0.056 15.2 1.6 1 23 398 421 398 421 0.96
11 17 0.00098 0.15 13.8 1.5 1 23 426 449 426 449 0.97
12 17 0.00022 0.034 15.9 2.1 1 23 455 478 455 478 0.95
13 17 0.0012 0.18 13.6 2.0 2 23 485 507 484 507 0.95
14 17 0.0043 0.66 11.8 0.3 1 23 512 534 512 534 0.96
15 17 0.00067 0.11 14.3 0.5 3 23 542 561 541 561 0.98
16 17 6.1e-06 0.00095 20.8 0.1 1 23 567 589 567 589 0.97
17 17 0.00095 0.15 13.9 0.4 1 23 595 617 595 617 0.97

Sequence Information

Coding Sequence
ATGGAAGGAATCAAGAACGAAGGCATTCGGGGTCCCCATGCATTCTTTATCGAGACATCTCCAAGTATCGCCGAGATAATCAACACGGAGAGCAGTAAAGAAAACAGAAATGTAGTGAGACGCCTGCATTACGCCTGCGACGTTTGCTCGTTCCCCTGTCGGACGAAGGGAAACTTAAGAAAGCACATGCAGCTCCACAAGTACACGTGTAGAACCTGCAACGAGCGGTTCGCCTCGTCGGAGAAGCTGGAACTTCACATGGTCGTGCATCACGGCGAGCCCAAGTACACCTGCAAACTGTGCTACTCCGTCGTGTGGAACAAGCCGGACATGAAGAAGCACTTCCTCGCGAGCCACTTGGATCCTTTCTGCAACACGTGCACCGCCTGCAACAAGGTGTTTCAATCGAAGTACGCTATAGAGAGGCACATGTACAGCCAGCACACGAAACTCTCGGTGGCGTGCACCATTTGTAGACGCGTCTACAACAGTTACCACGCGCTCAAGGCGCACACCAAGCTCATTCACCTGAAGACCGGCTACCAGTGCGAGATCTGCAAGCGGCGTCTCCTCTCCGCGGATTCTCTGGAGGCGCACCTACGACGGCACGAGGGCACGCGAAACATGGACAGCTACATCTGCACAACGTGCGGCGAGACCTTTCTCACGAAAAACAAGCTGAACAAACACGTGACCATCCACGGCGAGATCAATCCCTACGTCTGCCCGGTCTGCCAGAAAGCCTTCGAGAAACGGGCGAATCAGGTGCAACATATTCTGACGCACATGAGTAACGTTTACGCGTGCGACATATGCGGGTTGAGGTACTCGCGAAGGGCTGCCCTGATATGGCACAGGAAAATGCATCCTGGACCGCTCGGTAAACTGCCAGTTATACCCGTGATAGGCATTGTGAGCGAAGTGGATCCGTTGAATGTTGAATCCAATGTCCAGAAACCATTTGTCGGAATCGAATGTGAATGgacgaaaagagaaaaatcgtTAACAGAACATGAAGGACGACCATCGGAAAAGATAAGTGCAAGTCTAACGAGAGAAAAGCTTAGTTCGCGGATCGTAACCGAGGAAAATCGACCGACTAGAAAGAAGACGACGTGCGTGGAGTGCGATCACTGTCGCCGCAAGTTCTTGAAGAAGAGCAACCTCGCCGAGCATCTGAAGCAGCATAGGCACAAATGCGCCGACTGCCCGAAGACCTTCAGCCTTCGGCGTTATCTGGTCTCCCACGTCGAGAAGAATCATCGGCAGCAGATGTACGAGTGTAGCGTGTGCAAGTACAAAAGCAACAACAAAGGTACCCTGAAGAATCACTACATCCGTCTGCACACGAGTAACTACGACTACGCGTGTGACACGTGCGGCAAGCAGTTCAAGATAAAGAAGGCCCTGAATCACCACGTGAAGCAGAATCACAGCGAGGCTCCGCCGATCGTGTGTGACGTCTGCGGTCACTTCAGTAAGAATCTCCACGCCCTCAAGGCTCACATGAAGTACAGGCATTACAAGCCGGAGTTTGTCTGCCGGATATGTCGACGGGGTATGACGACACAGGAGAACTTGGAGCAGCATCTTACGTGGCACGAAACCAGGGAGAAGGTACTCTGTCCGACTTGCGGCAAGAGATTCCGGGGACGCGATCTGGACTCGCACATGAGAGTGCACACCGGGGTGAAGCCGTTCCCCTGCCCAGTCTGCGGAAAGACTTTTCGACGGCAAACTGCTCAAGAGCAGCACGTGTTGATCCACACCGGAAAGAGACCCTACATTTGCGATATTTGCGGTCAAGCGTTCGCTCAAAAGCCCGGTTTAATCTGCCACAGGAAGAGACATCCTGGCCCGCTGCCCCCGCTACCTGTAGTCTCCATCAAGAACATCGTCACGGAATTCACGAAAGAATACGCGACGAAAAACGCAGTCATAAAGATTGAATAA
Protein Sequence
MEGIKNEGIRGPHAFFIETSPSIAEIINTESSKENRNVVRRLHYACDVCSFPCRTKGNLRKHMQLHKYTCRTCNERFASSEKLELHMVVHHGEPKYTCKLCYSVVWNKPDMKKHFLASHLDPFCNTCTACNKVFQSKYAIERHMYSQHTKLSVACTICRRVYNSYHALKAHTKLIHLKTGYQCEICKRRLLSADSLEAHLRRHEGTRNMDSYICTTCGETFLTKNKLNKHVTIHGEINPYVCPVCQKAFEKRANQVQHILTHMSNVYACDICGLRYSRRAALIWHRKMHPGPLGKLPVIPVIGIVSEVDPLNVESNVQKPFVGIECEWTKREKSLTEHEGRPSEKISASLTREKLSSRIVTEENRPTRKKTTCVECDHCRRKFLKKSNLAEHLKQHRHKCADCPKTFSLRRYLVSHVEKNHRQQMYECSVCKYKSNNKGTLKNHYIRLHTSNYDYACDTCGKQFKIKKALNHHVKQNHSEAPPIVCDVCGHFSKNLHALKAHMKYRHYKPEFVCRICRRGMTTQENLEQHLTWHETREKVLCPTCGKRFRGRDLDSHMRVHTGVKPFPCPVCGKTFRRQTAQEQHVLIHTGKRPYICDICGQAFAQKPGLICHRKRHPGPLPPLPVVSIKNIVTEFTKEYATKNAVIKIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01229186;
90% Identity
iTF_01421711;
80% Identity
-