Tlon012205.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Temnothorax longispinosus
Gene Symbol
ken
Assembly
GCA_004794745.1
Location
QBLH01002723.1:572924-574992[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.7e-16 8.8e-14 51.1 0.0 9 97 30 114 25 117 0.93

Sequence Information

Coding Sequence
ATGTATTCTGACGGTCTCTTGACGCTCCATTATGGGAAACATCCAGCGACCTTGGCCGCAGAGGTCGGGGCCTGGTACAGCGGGGACCGTCACGTGGACGTGACACTGGCGTGCGACGATGGGTCCGTCGTGAAGGCCCATCGCGTCGTTTTGGCAGCCGCCAGTCCCCTCTTAGCTAGTCTACTTCGGAATCCTGCCCTGGATCATGTGGTTCACTTATCAGGCGTCCGAAAGGCacaattaaatcatttacTGGAGTTTTTATATAACGGAGAGGCATTGATACCGTCGACAGAGCTTACACCATTGAGGGAGCTCTTCGAGGTTCTGCAGATTAAGTCAGAGCTATTTGAGCCCAATCAACCTCAAACTAGTAACTCTGATCCCGAAAGAATATCAACTCCGCAGCCCTCAGAAGGCCAGGAGAGTTCCAGTTACGAATCCCAATACGATGGCAGACAGTCCAATAATCCCGCGGACTGTTGCTCAGTCCTAATCAAAACGGAAGGCTGCGAAGAGGAACCGGAAGTGGATGTGGAAGGTGTGGAAGGCGAAAGTCTTCTCTCGGATAACAGAGAGAGCAGCATAGAACCTCCCAGAAGAAGGGATAGTTCCGATCCTGTTAATCTCAGTCTCAATTCCGGCACTTCCGTCACAAGCGACAGCTCGCACGATATAATACACAGTAGGTCTGAAAAGCCGATATTTGAGAGGCGAGAATCTCTTGAGGAGGctgaagagaggaagaggcaGCTGGCGGCGCGGCTGGCGTTAGGCTTAGAATCTGGGAAGAGAAAACTCGAGGAGATACCGATCCCACCTGCGGAGGCGTACGTCGTGACGCCTCATCGAAAGCGAAGGCCAGGCTTCCACAATGCACCCGCACAAAATCCGGCCTTCGTGCCCTTTAATCCTGGATTTGAAACGCCAAGAAGGTTACAGGCGCCGCATCCCCTGAGCGTTTCGGCACCACCATATCTGCAGGATAGATCGGTGACACCGCCATCGCATCGACCACCGAGCGCCGATCCGGCGTCAGCAGCGGCACTGGAGCCACCTTGGACTACCTGGACTCTGCCGAGAGctccaccgccgccaccgtcaACGGACGACCCGCCGAAGTCCACTCCTGTTCGAGAATACCGATGCAGCTATTGTGGCAAACAGTTTGGCATGTCGTGGAACTTAAAGACCCATCTTAGAGTGCACACGGGCGAGAAGCCTTTTGCGTGTAGACTTTGCGTTGCCATGTTCAAGCAAAAAGCTCACTTGCTGAAGCACCTTTGCTCGGTGCATCGAGGTGTGATAGCCGCTCCCGACAATACCTTCTCGTGTTGCTTCTGCTCGTCGTCGAACTTCGTCAATCTGCAGGACCTCATCAGGCATCTCTCGGGGCCGCACAATAATCTGCTGCTCAGCAGGAATCTACATCGCGAATTTGCGAATCACGAATAA
Protein Sequence
MYSDGLLTLHYGKHPATLAAEVGAWYSGDRHVDVTLACDDGSVVKAHRVVLAAASPLLASLLRNPALDHVVHLSGVRKAQLNHLLEFLYNGEALIPSTELTPLRELFEVLQIKSELFEPNQPQTSNSDPERISTPQPSEGQESSSYESQYDGRQSNNPADCCSVLIKTEGCEEEPEVDVEGVEGESLLSDNRESSIEPPRRRDSSDPVNLSLNSGTSVTSDSSHDIIHSRSEKPIFERRESLEEAEERKRQLAARLALGLESGKRKLEEIPIPPAEAYVVTPHRKRRPGFHNAPAQNPAFVPFNPGFETPRRLQAPHPLSVSAPPYLQDRSVTPPSHRPPSADPASAAALEPPWTTWTLPRAPPPPPSTDDPPKSTPVREYRCSYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRGVIAAPDNTFSCCFCSSSNFVNLQDLIRHLSGPHNNLLLSRNLHREFANHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01477755;
90% Identity
iTF_01406866; iTF_00181625; iTF_00015041; iTF_00130113; iTF_00417730; iTF_00126116; iTF_00016805; iTF_00016166; iTF_00182727; iTF_00417928; iTF_00129129; iTF_01523690; iTF_01477228; iTF_00014862; iTF_00127822; iTF_00015503; iTF_00182095; iTF_00126865; iTF_00128369; iTF_00016979; iTF_00127091; iTF_00182291; iTF_00015701; iTF_00129365; iTF_00129878; iTF_01477046; iTF_01261944; iTF_01523512; iTF_00128601; iTF_00016346; iTF_00181434; iTF_01477946; iTF_01262107; iTF_01477755; iTF_00126334; iTF_00127614; iTF_00182944; iTF_01405916; iTF_00765796; iTF_01408421; iTF_00385927; iTF_01407786; iTF_01423050; iTF_00885291; iTF_01424011; iTF_01423276; iTF_00766030; iTF_01408686; iTF_01421870; iTF_01407535; iTF_01409583; iTF_01421679; iTF_01422353; iTF_01423795; iTF_00385692; iTF_01409340; iTF_00885533; iTF_01406141; iTF_01422557; iTF_00869254; iTF_00731105; iTF_00868422; iTF_00867815; iTF_01245351; iTF_00729705; iTF_00280683; iTF_00280078; iTF_00264656; iTF_00280304; iTF_00264433; iTF_00868241; iTF_00280788; iTF_00869013; iTF_00730907; iTF_00867582; iTF_00729471; iTF_01245568; iTF_00265316; iTF_00730377; iTF_00730198; iTF_00265151; iTF_01355556; iTF_01355755; iTF_01354957; iTF_01354745; iTF_01077813; iTF_01077604; iTF_01254944; iTF_01016173; iTF_01015977; iTF_01099538; iTF_01099362; iTF_00110165; iTF_00109958; iTF_01520412; iTF_01520613;
80% Identity
iTF_01406866;