Tlon009249.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Temnothorax longispinosus
Gene Symbol
bab2
Assembly
GCA_004794745.1
Location
QBLH01001066.1:300694-306353[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.8e-26 5.4e-24 84.0 0.0 3 104 57 155 55 161 0.91

Sequence Information

Coding Sequence
ATGAGAGAGGAGCAGTGGAGCAGTGAAGTGAAGTGGAGCAGTGTCGCGCTGAGAACGATCGTTTTGCGGCGGACGAGCGATTTTTCACGAGCAGGTAGCAATATGGAAGGTCAACAGTTCTGTTTGCGATggcataattttcaaaatactcTCTTGAGCTCGCTTCCAAAGTTGCTGGATGGAGGTCACCTGACAGACGTTACGCTCAGCGCCGGCGGTAGACACATTCATGCTCACAGAATCATACTCTCGGCTtgtagttattattttaaagaactctttaagGACTTGAACTCCTTGCAACATCCGGTCATTGTGCTACCAGGCATGGAATATGCAAATCTGTGCGCTCTGGTCAAGTTTATGTATAATGGAGAAGTGAATATTTATCAAGAGCAATTACCTGCACTTTTAGCTATGGCTGACACATTGCACATTTGTGGATTAGCTGATATGGCTGGGaaaaattcgAGACAGGATAACGGCTTGTATGTGCAATCGTCAGTAGTGCATCCTCAGGAAAGACTATCGAACGAAGAGATAATAAAGACGGAGTCGAAAGACAATATAACGGCTACTGGATCATCAGAATCGGTATCAGTACCCTTGCCTAAAGTAATGGATAATTTAGAGGATTACGAGCCTAGCAACGATCAAGAAAGTATACCGTATTGCGTTAAGACGAAGCCATATTACTCCATAAATGCGAAGCTAAACCAAAGGGAGAAAACGTCTGTTCCTGTTAACGCGTCTGCTAATAAGTATATCGATAGAGGCTACTCAGAGAATATAGCGGATGAGGCAGCGTCGATCGTGGAGGATCAAGTTACCCCTATAGAAGATGTAAAACCACCGCCAGCCGTGTGGGACGCGAGTTTCAAGTTGCTTACGGCGTCTGCACCCAATAGAACTTCCCAGACTTACAACAAATCCAGTGTCACTTGTCTTATCTGTGGTAAACAATTGAGTAATCAGTACAACTTGCGAGTACACATGGAGACGCATAGCAATAGCTCGTACAGCTGCACATCGTGTTCGCATgtatcgcgatcgcgagacGCACTTAGGAAACACGTGTCCTACAGGCACCCGGTAGCTTCTTCTCAAAAACGTCCACGGTATAATACGTCAAAATCATCAATAATATGA
Protein Sequence
MREEQWSSEVKWSSVALRTIVLRRTSDFSRAGSNMEGQQFCLRWHNFQNTLLSSLPKLLDGGHLTDVTLSAGGRHIHAHRIILSACSYYFKELFKDLNSLQHPVIVLPGMEYANLCALVKFMYNGEVNIYQEQLPALLAMADTLHICGLADMAGKNSRQDNGLYVQSSVVHPQERLSNEEIIKTESKDNITATGSSESVSVPLPKVMDNLEDYEPSNDQESIPYCVKTKPYYSINAKLNQREKTSVPVNASANKYIDRGYSENIADEAASIVEDQVTPIEDVKPPPAVWDASFKLLTASAPNRTSQTYNKSSVTCLICGKQLSNQYNLRVHMETHSNSSYSCTSCSHVSRSRDALRKHVSYRHPVASSQKRPRYNTSKSSII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01409314; iTF_01405892; iTF_01409575; iTF_00766024; iTF_01408396; iTF_00765773; iTF_01406862; iTF_01407507; iTF_00885269; iTF_00885525; iTF_01406134; iTF_01408667; iTF_01407775; iTF_00265121; iTF_00264647; iTF_00264402; iTF_00265312; iTF_00127811; iTF_00129892; iTF_00127079; iTF_00127591; iTF_00126088; iTF_00129356; iTF_00128593; iTF_00129105; iTF_00126324; iTF_00126837; iTF_00128341; iTF_00130103; iTF_00280291; iTF_00729697; iTF_01077579; iTF_01245327; iTF_01077809; iTF_01245556; iTF_00731093; iTF_00280060; iTF_00729439; iTF_00730879; iTF_01229124; iTF_01229377; iTF_01520393; iTF_01520609; iTF_00110157; iTF_00109932; iTF_01355760; iTF_01355536; iTF_00899164; iTF_00898892; iTF_00385919; iTF_00385671; iTF_01354720; iTF_01354965; iTF_01523488; iTF_01523687; iTF_01476579; iTF_01261921; iTF_00016130; iTF_01476357; iTF_01477225; iTF_00182283; iTF_00014829; iTF_00015697; iTF_00016338; iTF_00181619; iTF_00015477; iTF_01262102; iTF_00182071; iTF_00182712; iTF_00015035; iTF_00182939; iTF_01477022; iTF_00181408; iTF_00730373; iTF_01255174; iTF_00730170; iTF_01254911; iTF_00868975; iTF_00867549; iTF_00867805; iTF_00869246; iTF_01015957; iTF_01268389; iTF_01267171; iTF_01268613; iTF_01271334; iTF_01271560; iTF_01269165; iTF_01270127; iTF_01269905; iTF_01267890; iTF_01266969; iTF_01269401; iTF_01267675; iTF_01270830; iTF_01270625; iTF_00417703; iTF_00417923; iTF_01477723; iTF_01477940;
90% Identity
iTF_01015957;
80% Identity
iTF_01405892; iTF_01406862; iTF_01406134;