Basic Information

Insect: Teleopsis dalmanni
Gene Symbol: MBD-R2
Assembly: GCA_002237135.5
Location: CM026971.3:105516799-105522714[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.4e-22 2.9e-18 66.6 0.1 3 76 406 477 404 478 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.4e-22	2.9e-18	66.6	0.1	3	76	406	477	404	478	0.93

Sequence Information

Coding Sequence: ATGGGGCGACGCTGCTGCGTAGCTGGCTGCAATTCAACAACACGTCTACCGGAGCACCACGGTGTCACTTACCATTCGTTTCCATTGGATAGCACAATCCGTTCGATTTGGTTACGTAACAGCCGTTTCAGCAACGAGCGACAAATAACAAAAAGCGTTTTGGTGTGCTCGCGCCATTTCCGACGTGCCGATTTTCAACCACAACGCAGTGGCAAATATCTTCTGAAGCCGCGTGTATTTCCAACAGTTTTTCCATGGGGCAGAGTAGACGCCGCGCAAATAGAAGCTGATCTTGAGACAGTGAAAAAGATTAAGCCATCGCAGCATACAAATGCGACCTCAGATAGTGCACCAACCGCTGAAGATGCTACCAAAGCAACCGTTGAGGCAACAGTGGCACAAATTTTAAAGGAGACGGCCACACTTAATGCCGCTGCAGcagcagaaaataaaaatgttttaaacaaaGATGAAAGTGCAAGTACATTGGGCGCAGCTATAAAATTCGAACCGGTCACTGAATTCGTTTCGGGAGCGCGCATTGAAGCACAAGACTTTGATGGTAACTGGCATACCGCGCGTGTAGTTGAAGTTGACAATGATGATCGTGAGGTGTTGATTAAATTTGAACGCACTGGGAAAATCAAGTCTGCTGTTGTTGGTGCTGAAGAATGGATATCAATGAACTCCACGCGTTTACGTCAACGGGCAACAAGTAAACCAGTTCCAGTATTTGAATTGgaagaaaaatgtttagcaCGTTGGTCTGGTCCGCGAAAATTTCCGGGCACAATCAAAAAAGTACTTGGCAATAACGCCTATGAGGTGTTGTTTGACGACGGTTATGTCAAGAATGTGCGAGCTGTGCATATGGTTAAATTAGTAGCAAGTCCTGCCGTTGCTGAAAACGATGTAAAAGCGAGACGTAGCGAGTTAGCTACAACTCAAACCATTACAGCAACTTCGACACCAGTCAAAGCgttgtccacagataaaatatcTAAAGAGGACCCAGCTGAGAAACCCGTCGAAGCAGTAAGACGCTCTACTTCTGCACAAGTTAAGGATTGGCCACTACTTGATATGTCTAAAATTGATTTGGcttcTCTTAACCTACCACAAATACCGCGCGACGGTGAGTGGACCTGTCACTGGGTGAATGATCAACCAATTGGACGTGAAGGTTTTCTAATAGTAGGGGAACATCGCAAGCCCACAGTAATTGTAGACGATTGGCGTTTGCCTTCTGGTTGGGTAAAGCACATGTATCAACGTTCGAATTTATTGGGCAAGTGGGATGTCATACTTGTCTCACCCATCGGCAAGCGTTTCCGTTCGAAAGCggatttgaaacaatttttggaAGAAAAAGGACAAGTTTATAATCCCGATATATATGATTTCAGCATACACAGACGTCGTGCTAAAGATATAAATGCTTATGCCTTTACGCCTGGTTACACACCTCATCAACCATACAAAACAAAAGTGAACACTTCAGCTAATGCAAGTGCTAGCAACACTTCGGATTTGTTGTCAACCTCCGTGACTACTCCAAGTGCTGCACAGTATATTGAAACACCGGTAGCTGGTGCAGCACCACCCGCTGAGCTACTTAACGCAACGGTTGATATAAAATCGGaaactgaagaaaaaaaacCAGATTTATCTACACTAGGACTAAGTTCTGATTCACCTAAAAGGAGCACAATTTTGGAAGATGGTTACGCTTACGTTGGTGGTTTAAAAGTGCAAATTGTTGATAATCTATTTCGTTGTCCTGAAGTGGGCTGTTCCAAGAACTTTCGAAAGGAAAACCATTTACAAATACATATCAAACATTAtcatcaaaatttaacaaaaTTATTGGGTGCTTGCCCAAAAATGCAGGAATTAGCTGAGAAGCGTACACATACACTACCAGATCCCAATGAGCCACAGCCTAAGAACCAAATACCAAATCAGGAGTTTTTTGCAAAAATGCATCAGCAGGACATGCAAAATTCACGTTCCAGAGGTAAGAGCTCGTTTCCTGATTCACCTGATTTGATTGGAGATATTAAAAAGGAAACTACCATGGACTTGaagcaagaaattaaaaatgaaatatctgaTACGGAAAACGTTACATTGGGTTCGATTAACATGGATACAACAATCAATACCACTGCAGATAGTTCAAGTATGTTGCCTTTAAGCTCTGCTGATGACTCGGCTCTAAATGTTTCGAATACTTCAACAAAGCGTTCCCGTTTCTCACCAACCAAACGAGTTTCTGGTGCGCGTAAAAGTAACCGGCAACGTACTACGCGTCGTTATTTGACAGCTGCTCATAGCAGCGGTGCAACTATTCCATCTACTCCTGTTACGTCTGATAATCATTTCGGAGTGTCGGATTTCGAAGAAACTCGTCATTCCTTTAATGCAACTCCGGATGCCAAATTATTAGAGACACGAAAACGCAAGATCATTGCCGCACCAGTTACGCCAATTGATTCGCCAATAACTGCTGATTCCGGTTCGTCTTCGATTCAACATATATCGGCAACGGATCCTGAAGCTATTAACCGTCCTGAATATATCAAAGAAAATGGACAGCTTATTAAAATTGTTCGCATGCGTCAGGAGGAAATTATAAACTGTGTATGTGGTTTTTATGAAGAAGACGGTCTTATGATTCAGTGTGAACTGTGTCTTTGCTGGCAACATGGTTCttgtaatgaaattttcaaagaatCTGAAGTTCCAGAGAAATATATTTGTTCTATATGCCGTAATCCACAACGTGCGCGTGAATCTATGCTTTACAAACACGATCAGGATTGGTTGTATGAAGGTAAACTACCCGTTGGCAATTATCACACTAACTCTGGAAGTATACCAAAGCGCTTTGATTATCTTAAGTTAACACACACACTTACTGGTAATTTGCTTGAGATAAAGGATTTTATACATTCCTTACGTCTTAAAACTAACGTGGCTGGGAATCGTTGTCATCCCAAGTTGTATTTATGGGCTAATAAGTGGGATGATGTTAAAGGCGATGCAGAAGGAAAGGTGAATACTGAAACTAAGCCTGGGGAtgatgacaaaaataatattaaagttgtaGAAGGTTCAGTTAGTACCCCAGCTGTGGCAAATATACCAAACATCCCACAGCCAGAGGCAGCGATTGACACTGATGAATGTCAGCAAAGGTTATTGGAACATATTAAGGTGCAACAATCTAATATCGCTGCTCGCTTGGATTTGATTGAAGCAGACGTTGCTAgaaTTGAAAAAGAAGATGAGCTTGATGAGTTAAAGGGTTCcaatagtaattttaataaagaaatactaGCAACTTTCATAAAAGATATGGAGGCTGTAAGACAACTtgctaaattaaattgtttggaGCACAAGAAAAAAGCAGTGGCAGTATTAAATGCACGccctttataa
Protein Sequence: MGRRCCVAGCNSTTRLPEHHGVTYHSFPLDSTIRSIWLRNSRFSNERQITKSVLVCSRHFRRADFQPQRSGKYLLKPRVFPTVFPWGRVDAAQIEADLETVKKIKPSQHTNATSDSAPTAEDATKATVEATVAQILKETATLNAAAAAENKNVLNKDESASTLGAAIKFEPVTEFVSGARIEAQDFDGNWHTARVVEVDNDDREVLIKFERTGKIKSAVVGAEEWISMNSTRLRQRATSKPVPVFELEEKCLARWSGPRKFPGTIKKVLGNNAYEVLFDDGYVKNVRAVHMVKLVASPAVAENDVKARRSELATTQTITATSTPVKALSTDKISKEDPAEKPVEAVRRSTSAQVKDWPLLDMSKIDLASLNLPQIPRDGEWTCHWVNDQPIGREGFLIVGEHRKPTVIVDDWRLPSGWVKHMYQRSNLLGKWDVILVSPIGKRFRSKADLKQFLEEKGQVYNPDIYDFSIHRRRAKDINAYAFTPGYTPHQPYKTKVNTSANASASNTSDLLSTSVTTPSAAQYIETPVAGAAPPAELLNATVDIKSETEEKKPDLSTLGLSSDSPKRSTILEDGYAYVGGLKVQIVDNLFRCPEVGCSKNFRKENHLQIHIKHYHQNLTKLLGACPKMQELAEKRTHTLPDPNEPQPKNQIPNQEFFAKMHQQDMQNSRSRGKSSFPDSPDLIGDIKKETTMDLKQEIKNEISDTENVTLGSINMDTTINTTADSSSMLPLSSADDSALNVSNTSTKRSRFSPTKRVSGARKSNRQRTTRRYLTAAHSSGATIPSTPVTSDNHFGVSDFEETRHSFNATPDAKLLETRKRKIIAAPVTPIDSPITADSGSSSIQHISATDPEAINRPEYIKENGQLIKIVRMRQEEIINCVCGFYEEDGLMIQCELCLCWQHGSCNEIFKESEVPEKYICSICRNPQRARESMLYKHDQDWLYEGKLPVGNYHTNSGSIPKRFDYLKLTHTLTGNLLEIKDFIHSLRLKTNVAGNRCHPKLYLWANKWDDVKGDAEGKVNTETKPGDDDKNNIKVVEGSVSTPAVANIPNIPQPEAAIDTDECQQRLLEHIKVQQSNIAARLDLIEADVARIEKEDELDELKGSNSNFNKEILATFIKDMEAVRQLAKLNCLEHKKKAVAVLNARPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01404947;
90% Identity: iTF_01404947;
80% Identity: iTF_01404947;