Basic Information

Insect: Teleiodes luculella
Gene Symbol: ccdc124-b
Assembly: GCA_948473455.1
Location: OX419583.1:2108218-2110247[-]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 8.9 7.6e+03 -2.0 10.0 28 63 27 63 15 69 0.86

2 3 4.8 4.1e+03 -1.2 0.1 24 45 94 115 92 116 0.80

3 3 8.4e-08 7.1e-05 23.7 0.4 2 40 164 202 163 207 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	8.9	7.6e+03	-2.0	10.0	28	63	27	63	15	69	0.86
2	3	4.8	4.1e+03	-1.2	0.1	24	45	94	115	92	116	0.80
3	3	8.4e-08	7.1e-05	23.7	0.4	2	40	164	202	163	207	0.94

Sequence Information

Coding Sequence: ATGCCGAAAAAATTCCAAGGAGAGAATAGCAAAGCGGTGGCTGCGCGCGAGAGAAAAGAGGCGCAGAAAGTGGAGAAAGAACAGCAGCTAAAGAAGATGGTAGAAGATGCTGAATGGCACGACGATGACGACAAATTAAAGAAAAAACAACAGAAAAAGGATGAACAAGAAAAGAAGCGATTGGAACAGCTCCAGAAAAAAGCAGAAGCTAAAGCGTTGTTGGAGAAGGAATTAGAATCTATAAACAAAGTGTCCAAGACCGCCAAGGCTCCTCCTCCGCCAAAGATCACCCGAGCGCAGATCACACAGATGAAGGAGAAGACTGTCAAAGCAGAACCTGAGAAACCTGTGCCAGCACGAGTGGTCGTGGAAGAACCACCTCTGGAGGAGAATCTCAACAGGATACAGCTGGATGGAGAGGTGGCACAGTCTGTGGACGAGGCTTTAGCTATACTCACTGACAAATCCGATGTCGACCGGCATCCAGAGAAACGACAGAAGGCTGCATACACAGCGTTCGAAGAAGCCAACCTCCCGCGAATCAAAGCAGAGAACCCCACCTTACGGCTGTCGCAGCTCAAACAAATGCTCCGGAAAGAGTGGCTTAAATCACCTCAAAACCCTCTCAACCAGAAGACGCAGTGA
Protein Sequence: MPKKFQGENSKAVAARERKEAQKVEKEQQLKKMVEDAEWHDDDDKLKKKQQKKDEQEKKRLEQLQKKAEAKALLEKELESINKVSKTAKAPPPPKITRAQITQMKEKTVKAEPEKPVPARVVVEEPPLEENLNRIQLDGEVAQSVDEALAILTDKSDVDRHPEKRQKAAYTAFEEANLPRIKAENPTLRLSQLKQMLRKEWLKSPQNPLNQKTQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00256919;
90% Identity: iTF_01403436;
80% Identity: -