Tacr022338.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tachystola acroxantha
Gene Symbol
egg
Assembly
GCA_963506565.1
Location
OY735897.1:4083094-4118524[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.46 1.7e+03 -0.8 0.1 16 38 1761 1806 1756 1808 0.80
2 2 5.8e-12 2.2e-08 34.1 0.0 4 74 1838 1901 1835 1904 0.87

Sequence Information

Coding Sequence
ATGAGCTCTACAGACCAAGATGAAGGTATTTCTACGTCAAATATAGAGGATGCAGTCGATATTCCTTCTTCTGCATCACAGTTGGACTTTAGAAACGACGACAAGAATCCATCGAAAATTCCTTCAGAAACCAACATAAGTTTAGAGGGTACCGGAGACTGCGTAAGACCAACTAAAAGTGACAATGATGAGCCTAAACAAGGTTCAAATAATACTTTCAAAGAAGATGAAAAAAGAGGTGCTACAGACATAACTATGGGCAACCTTGGAGCTTATGGTAGTATCACTAAGTCTGGTTTGGAAGGCTCTACTATACAACATTCTGATAAGTTAGACAAGACTAATATTGATAAGTCAGATCAGACTAATACTGGTAAGTCAGACCAGACTACTACTTGTAAGTCAGATCAGCCTAATACTGATAAGTCGGACCAGACTGATTCTGATAAAGATATAATCATAAATGATGATAGCAATCCTCAGATGCTTACCGATAAGATACTTGAATGCAAAACTGTAACTAGTCCTACAGCAGACACTAGTAGCGATATTCAAGATGAAGAACTTGTCTTGAAATGGTATGACACTGAATCTGATGAAATGAGCGTGAAATCTAAAACGAATGATGATACCCTTAGCATTACATCAATAAAAggagataaaaataatgaatcaATTGAAACAGATGAAGAATCAATTGATAAGGATCTACTCAAAGCAATTGATACGCAAATATCTCAATTAGATGAAGAAATTACTAACTCACCAGATAAGACAGTTAGCGATgaaataattaatgaaaaagTACCACTTGAAAATACAGAAAAAGACAAAGATTCCACAAATGATAAGGTAATAAAAGCAAATGATAAAGAAATGTCTGCAATTGATGCTGATATACCTAGTGATATGGCTAAAAATGTTGACAAACCCATTATCGATGATAATATTGCCACATCAAGTAAAGTATTGGATGTATTAGTACCACTAAGTCTTACACCTACAGAAATTGACAAAACATCTATGGAAAGTGATGTACTTGAATCAAGTGATGCAGATATAGTCTTAAAATGTGTTGATGAAGATGATAAAGCTGAAGAAAGAGTCCAGGAGTCATTTAAGACTTTAATTGATGAAGTTAATGTAGATAATCCAACAAAGATTGATAAGAGTGATGATGCAAAGTTGATTAATACAGATGTGATTACAGAAAGTGATGCAGAGATATCGCAATTGGATGAAAAGCTCGCTAATTCTCCACATAAGACTACTACTGAGACATTTATTACTACTTCGAGTAAAGAATTTGATGATAAGGTACCACCAAGTCTTGAAAAGACAGAAATAGACAAAACATCCATTAAAGATCATGTAATCAAAGCTATTGATGAAGAAATAGCTACAATTGATGCACAGTTACCTAGTGATACGGTTAAAGATGTTGGCACAGCCATTGCTGATGAAAATATTGCTACCTCAACCAAAGTATTGAATGAAGTGCTATCAACAAATCCTGCAAAGACAGAATCAGACATAAAACTTAAGGAATCTGCTATACCCAAAGTAAAACATCCAGAAACATCTAGAATTGATGAGAAACTTCCTCATTCTGTAGCTAAAGATATTGAAAAGACTGAATTAGACAATAGTATCACAAAAAAAGATATACTTAAAACAATTGAtgcaaaaatattgaaattggacTCAGACCTACCTAGTTCTCCAAATAAATCCATAAATAAAACTACAGATGAGGATATAGTTACTTCTGATAATAAGTTGTTGGAAGAAATTGAACCACCAAGTGTTGCACAAACTGAATTAGATAAAAGTGCAGTGAAAAATGATATACTTGAAGTAACTAATGCTAAATCTCAATTAGATGAAGAACATAACAGTTCTGGAGATAAAGTTCAATTCATTGATGAACCTATAGCTTCAACGAGTAAAGTTTTTGATGAAATTGTACTACCGAAGTTAGAAAAAGATATAAATCCAGCAAAAGATATAGCAGAAGTAATTGATGCCCAAATATCTCAATTAGATGCACATACAGCAGTTAAAGCTAATATTTCTGATAATGCTAAGATTGATGAATCATTTGTAACTGAAGAATCAATGGCTGATACATCTGATGAAGTACCAGAAGTGACTGACAGTCTCGGGCTACTGGCTGAGTCGTCGAGGGTGATAGACCAGGATGACGAGGAACAGGAGACATCGGATCATGACGATGGAGACGATGAAGAGGATTTTGACCCTGATGATGAAAGCAGTAATCAGATGACAGCAGAGCATTCCGAAGACTCTAACGCACAGCATTCCGAGTCAGACGTACCCAGAGACAAACCTAACCTACCGACACATGTAGAGGCCTTAGACGATGCCCAGGACTTCATAGACAACACACCAGAGATAGAGAGTCCAATGGAAGATAGAGACGAGTTTAATTTTGCGATTACTAATGTTGTAAGCGCTGTCGGAGACATCCAAGATGTCTCTGTAGATGTGGAAGATGATATCTGTAATGagattGAAGATACGTTAACTGCTGATGATGACAACATTGAAGATGTTGACATAACCATAGAAGAAAGCACAATTGAAATTGAAGGGACAACTATCGTCGCTGAAGATATAACTATCGTAGCTGAAGATACAACGATTGAACCTAAAGACACAACAATTGAAGCTAAAGACTCAGCTTCCGAGGCTAAAGTCACAACTATCGACGCTAAAGACTCGGTTGTCAAAGCTAAAGACTCGGTTGTCAAAGGTAAAGACTCGGTTGTCAAAGGTAAAGACACAATGATCGAAGCTAAAGACACAGCTATTGAAGCTAAAGACACGACTGTCAAAGCTAAAGATATAACTATCGAAATTAAAGACGCAAGTTTGGAAACTAAAGAGACAGCTGTAGCAAAAACAATTCCTGATACAGAAACAGATCTATTAGACGAGTCGCTGTCAGACGCGGATACTGTCAAGTTGTCAGACACTTCTGACACCGATGAAACCGCTGGGACATATGAGTCGCATAAACTACGGAAGCTGCTCTCGAAAATGTCAGAAGAGAATGAAGAAAAGCAGTCTCCGAGCAAGCAGAAGAAATTGGAGATTGCCAAACCGAATAACGTCGTCAGCATAGTTGACCTAGAGGAGAGCTCGTCTGAGGATGATATCCAAGAGGTCGCGAAGACGCCCGACGAGGTGTCCGATGACGTCACCAATGTCAACATATCCGGTCAAATCGAGATCATGTCGTCCGGCGGTAACACGTCGGACATTACGACCAAGAAAGGCGAGATCGTTATAAGCGGCGTGCCTAAACCACCGCCCATGAAACCTGCGAGATTGAACACTAGTGAGGTGACAATTAAGACTAAAAGGTCTGAGCCAGTCATAGTATATCCTCCAGCGAAAATAAAAAACCTTGAAACTAAGGACAAATTGAAACATATGAGTTTGGAGGTGTTCAATTTGGACTCCGACGAAGAGGGCAGTATACCGGATGATAAAGAGAAGCCCAAAGACAAGTTACCTCACAACAAGTGTGTGAACAGTCAATGCACGAGTGACAACAGCGTGGCGTACTACGCGGCGAACCCCTCCTCGGTGGCGTACTACGATCCTGGCAGGAAGAAGAGGGCCATGATATGCGCGGTGTGCGCGGATAAGTTGGATGCGAGGGCACAGAGACTAATAGAAGGCATACGGAACCTGACTCCACTGCTCTCGCTGGAGATGGGTTCCATACGCCAGGAGCTGGTGGAGATATCGGACTCCGACTCTGATGATGATACCGACAGCCGTGATGGGGAGAAGGACACTATTGGTGTGGAGGGGGCTAGTGTCGTCGAGGAGAAGCTGTCCCGGCTGCTCAACGAGACGTGGCTCAAGTACAAGCTGGACGACAGGCTCAAGGAGGCGCACGACGAGCTCGCCGCAGACATGGAAAGGCTGGAGAAGGAGAGCAAAGAAGTGGACACGATGCTGACCGAGTGTCAAGTAGCTACGGACAAGCTGCGTCACGAGCTGTACACGAGCTTCGAGCGTGAGGGACAACAAATGCCGCCCATTGTCGTGTTCGATACGCCGGACAACGTGTTCACGTGTACCGAGGCTGACCAATTAGCCAACTTAGTTACAGAGGCCAAGGCCAGCAAGCGTCGCCTGTCGTCCCCTAGTGCGAGCGAGACGGCGTCGAAGCGAGCCGCCATCCCGCTCGGCTACGCGCCGCTGGACAATGAGACAATACAGCCTAAGACGACACCTGCGGAGGATAAGGACGTCAAACCCCTGGTTCCAGCTCCGGTACCCTTTATTTCGGACGCGGCTAAAGTGGACGATGACAAAGACATCTCTGTAGTGAACCTGTCAGCCGAGGCCGCTCCCGCGGACCTGCCCCCTCCCGGCGACATCACTCGGCCGCCGCTGCGTGTGGGCATGCAGATCTATGCCATGCGAAACGCGTTCGGTTCCTGGCTACGTGGTAAAGTTGTCGAGTGTACTCCTAAAGGATCTGGTGCTGCGTCTCAGTTCACTCTGTGCCGCGTCCGCTTCGAGAACAAAACGAATAAGAGCGCCTTCAAGCTGCTGCCGGCGCGCTCCCTCGCGTACAGCGAGCCGGCTGAAGTCAGGATGACGATAGGCACACGTCTGATCGCGCTATTCAAGGACACAATGCAGCCGGCGCGCCGCGAGTCCTTCTACTCGGGCGTCGTGTCCGAGGTCCCCAACCCGGTCAATAGCTACAGATATTTAGTCTTCTTCGACGACGGCTACGCGCAATACGTGCACCACAAGGACACCCGTCTAGTGTGCGAGTTCTCCCCGCTGGTGTGGGAGGAGGTGCACCCGTTCTCCCGGGACTTCGTCCGGGAGTACCTGCTGGCGTACCCGGAGAGACCCATGGTCCGGCTGCATACCGGGCAGAGCTTGAAGACCGAATGGAATGGCAAATGGTGGCTATCCCGAGTGGTCCAAGTGGACGCGTCGTTAGTGCACGTGCACTTCCAAGAGGACAACCGCACCGAGTGGATATACCGCGGCTCCACGCGCCTCGCGCCGTTGTATTTAGAACTGCAGGCCGCCGAGAGGCACAGGGCGCGGCCGTTGCCTAGAAACAGGATTCAGAACAAGGTGAACATGCCTTACGTCGAGTACACGCGTTCTGACGAGCTGCCGCCCGTCAAGCCCGCGACTCAGCCACAGACGCACACTCTAGCACAAGCTCAGGCGCAAATTCACGCGCAGTCCCAGCAAGAGGAGTTCCGTCGTCAGCGCTCCGTGGCGAAGAAGTCTACGGGCGCGTCGCAGCCGCctccgcccgcgcccgcgccgcacgcgccgcgcccgcTGCCCATGCCCGTCGGGCCCGTCGACAGCGTACAGAGCAGGGTCGTGTACTATACGCCCAAGAACGCGGTGCGCCCCTACAAGATGGTGCCCCACTCGTGCAGCCCGCGCTGCAAGCGCAACGACGTGCTCGCGCTCAACGACCTCAGGACATACAACCCGCTCGCCAAGCCTCTACTCAGTGGATGGGAGAGACAAATAGTCCGCGTGAAGAGCCTGAAGCAGGTAATGTACCGCGCTCCGTGCGGCCGGCGCCTGCGCAACATGCGCGAGCTGCACCGCTACCTGCGCGCCGTGCACTCGGACATGGGGGTCGACCTGTTCGACTTCGGACCCACCACCAACTGCCTGGCAGAATTCGTGCTCAATAAGTGTATTATTGCCAAGAAGGACCTGTCGAACGGCAAAGAGAACGTGCCCGTTCCCTGCGTGAACTACTACGACAGCTCGCTGCCCGAGTTCTGTTCGTACAACACGGAGCGGACGCCCACAGAGGGCGTGCCGCTCAACCTCGACCCCGACTTCCTGTGCGGATGCGACTGCGCGGACGACTGCGAGGACAAGTCCAAGTGCGCTTGCTGGCAGATGACGCTGGAGGGCGCGCGCACCATCGGCGCTGATAGCCGCCGCGTCGGCTACGTGTACAAGCGGCTGCCGGAGCCGCTCTCATCCGGCATTTATGAGTGCAACTCAAGATGTAAATGCAAGAGCACTTGTCTCAACCGAGTGGCCCAGCATCCCTTACAACTGAAACTACAGGTATTCAAGACGCTGAATCGCGGCTGGGGCATCCGCGCACTCAACGACGTGCCCAAGGGCGCATTCCTGTGCGTCTACGCCGGGAACTTGCTCACTGACGCCACGGCAAACTTGGACGGTCTGAACGAGGGCGACGAGTACCTGGCCGAGCTGGACTACATCGAGGTGGTGGAGCAGATGAAGGAGGGCTACGAGGAGGACATTCCCAACGCGGACAAGAAACTGGACCAGAAGCAAAGCGGCGACGACTCCAGCACCGAGGAGTCGTCTCCATCAGAAGACGAGAGCACCTCATCCAAAAGCAAGAAGGACGACGGCGACTTCGAACCGGGTTACACGTACAGGGTCACGGAGTTCAGCAAGCGTCTTCGCAAGCGAGAAAAGAGCAAGAAAGAGAAGGAAGATGGCGCTTCCGGCGAAAAGAACAAAGATAGCGGTAAAGATAAAGGAGAAGGCGATTGTATCACCATCAGTGATGATGAGGAAGTGAGAGAGCCGTCCCGTTTCATGGCTCAGGCCGGTATGGGGGGTAACCAGTTCATATCTAAGCACAAGTCTGTGCGGTCGTATTTCGGCGAAGACGAGGCGTGCTACATCATGGACGCCAAGGTTCAGGGCAACATCGGCAGGTATCTCAATCATTCGTGTTCCCCCAACGTGTTCGTGCAGAACGTGTTCGTGGACACGCACGACCCGCGCTTCCCGTGGGTCGCGTTCTTCGCGCTGTGGCCCATCCGCGCGGGCACAGAGCTCACGTGGAACTACAACTACGACGTGGGCTCGGTGCCCGGCAAGGTGCTCTACTGCTACTGCGGCGCGGTCAACTGCAGGGGCAGGCTGCTCTAG
Protein Sequence
MSSTDQDEGISTSNIEDAVDIPSSASQLDFRNDDKNPSKIPSETNISLEGTGDCVRPTKSDNDEPKQGSNNTFKEDEKRGATDITMGNLGAYGSITKSGLEGSTIQHSDKLDKTNIDKSDQTNTGKSDQTTTCKSDQPNTDKSDQTDSDKDIIINDDSNPQMLTDKILECKTVTSPTADTSSDIQDEELVLKWYDTESDEMSVKSKTNDDTLSITSIKGDKNNESIETDEESIDKDLLKAIDTQISQLDEEITNSPDKTVSDEIINEKVPLENTEKDKDSTNDKVIKANDKEMSAIDADIPSDMAKNVDKPIIDDNIATSSKVLDVLVPLSLTPTEIDKTSMESDVLESSDADIVLKCVDEDDKAEERVQESFKTLIDEVNVDNPTKIDKSDDAKLINTDVITESDAEISQLDEKLANSPHKTTTETFITTSSKEFDDKVPPSLEKTEIDKTSIKDHVIKAIDEEIATIDAQLPSDTVKDVGTAIADENIATSTKVLNEVLSTNPAKTESDIKLKESAIPKVKHPETSRIDEKLPHSVAKDIEKTELDNSITKKDILKTIDAKILKLDSDLPSSPNKSINKTTDEDIVTSDNKLLEEIEPPSVAQTELDKSAVKNDILEVTNAKSQLDEEHNSSGDKVQFIDEPIASTSKVFDEIVLPKLEKDINPAKDIAEVIDAQISQLDAHTAVKANISDNAKIDESFVTEESMADTSDEVPEVTDSLGLLAESSRVIDQDDEEQETSDHDDGDDEEDFDPDDESSNQMTAEHSEDSNAQHSESDVPRDKPNLPTHVEALDDAQDFIDNTPEIESPMEDRDEFNFAITNVVSAVGDIQDVSVDVEDDICNEIEDTLTADDDNIEDVDITIEESTIEIEGTTIVAEDITIVAEDTTIEPKDTTIEAKDSASEAKVTTIDAKDSVVKAKDSVVKGKDSVVKGKDTMIEAKDTAIEAKDTTVKAKDITIEIKDASLETKETAVAKTIPDTETDLLDESLSDADTVKLSDTSDTDETAGTYESHKLRKLLSKMSEENEEKQSPSKQKKLEIAKPNNVVSIVDLEESSSEDDIQEVAKTPDEVSDDVTNVNISGQIEIMSSGGNTSDITTKKGEIVISGVPKPPPMKPARLNTSEVTIKTKRSEPVIVYPPAKIKNLETKDKLKHMSLEVFNLDSDEEGSIPDDKEKPKDKLPHNKCVNSQCTSDNSVAYYAANPSSVAYYDPGRKKRAMICAVCADKLDARAQRLIEGIRNLTPLLSLEMGSIRQELVEISDSDSDDDTDSRDGEKDTIGVEGASVVEEKLSRLLNETWLKYKLDDRLKEAHDELAADMERLEKESKEVDTMLTECQVATDKLRHELYTSFEREGQQMPPIVVFDTPDNVFTCTEADQLANLVTEAKASKRRLSSPSASETASKRAAIPLGYAPLDNETIQPKTTPAEDKDVKPLVPAPVPFISDAAKVDDDKDISVVNLSAEAAPADLPPPGDITRPPLRVGMQIYAMRNAFGSWLRGKVVECTPKGSGAASQFTLCRVRFENKTNKSAFKLLPARSLAYSEPAEVRMTIGTRLIALFKDTMQPARRESFYSGVVSEVPNPVNSYRYLVFFDDGYAQYVHHKDTRLVCEFSPLVWEEVHPFSRDFVREYLLAYPERPMVRLHTGQSLKTEWNGKWWLSRVVQVDASLVHVHFQEDNRTEWIYRGSTRLAPLYLELQAAERHRARPLPRNRIQNKVNMPYVEYTRSDELPPVKPATQPQTHTLAQAQAQIHAQSQQEEFRRQRSVAKKSTGASQPPPPAPAPHAPRPLPMPVGPVDSVQSRVVYYTPKNAVRPYKMVPHSCSPRCKRNDVLALNDLRTYNPLAKPLLSGWERQIVRVKSLKQVMYRAPCGRRLRNMRELHRYLRAVHSDMGVDLFDFGPTTNCLAEFVLNKCIIAKKDLSNGKENVPVPCVNYYDSSLPEFCSYNTERTPTEGVPLNLDPDFLCGCDCADDCEDKSKCACWQMTLEGARTIGADSRRVGYVYKRLPEPLSSGIYECNSRCKCKSTCLNRVAQHPLQLKLQVFKTLNRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPNADKKLDQKQSGDDSSTEESSPSEDESTSSKSKKDDGDFEPGYTYRVTEFSKRLRKREKSKKEKEDGASGEKNKDSGKDKGEGDCITISDDEEVREPSRFMAQAGMGGNQFISKHKSVRSYFGEDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALWPIRAGTELTWNYNYDVGSVPGKVLYCYCGAVNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-